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Volumn 23, Issue 2, 2016, Pages 694-702

Clinicopathologic Analysis of PD-L1 and PD-L2 Expression in Renal Cell Carcinoma: Association with Oncogenic Proteins Status

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; VASCULOTROPIN; CD274 PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; PDCD1LG2 PROTEIN, HUMAN; SCATTER FACTOR RECEPTOR; TUMOR MARKER; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

EID: 84958150013     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-015-4903-7     Document Type: Article
Times cited : (160)

References (30)
  • 1
    • 0033847587 scopus 로고    scopus 로고
    • Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma
    • PID: 10685660
    • Fisher RI, Rosenberg SA, Fyfe G. Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma. Cancer J Sci Am. 2000;6 Suppl 1:S55–7.
    • (2000) Cancer J Sci Am , vol.6 , pp. 55-57
    • Fisher, R.I.1    Rosenberg, S.A.2    Fyfe, G.3
  • 2
    • 16644401873 scopus 로고    scopus 로고
    • Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma
    • PID: 15625368, COI: 1:CAS:528:DC%2BD2MXpslaktw%3D%3D
    • McDermott DF, Regan MM, Clark JI, Flaherty LE, Weiss GR, Logan TF, et al. Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma. J Clin Oncol. 2005;23:133–41.
    • (2005) J Clin Oncol , vol.23 , pp. 133-141
    • McDermott, D.F.1    Regan, M.M.2    Clark, J.I.3    Flaherty, L.E.4    Weiss, G.R.5    Logan, T.F.6
  • 3
    • 77949890945 scopus 로고    scopus 로고
    • Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial
    • PID: 20100962, COI: 1:CAS:528:DC%2BC3cXktF2lt78%3D
    • Sternberg CN, Davis ID, Mardiak J, Szczylik C, Lee E, Wagstaff J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol. 2010;28:1061–8.
    • (2010) J Clin Oncol , vol.28 , pp. 1061-1068
    • Sternberg, C.N.1    Davis, I.D.2    Mardiak, J.3    Szczylik, C.4    Lee, E.5    Wagstaff, J.6
  • 4
    • 62849128369 scopus 로고    scopus 로고
    • Renal cell carcinoma
    • PID: 19269025, COI: 1:CAS:528:DC%2BD1MXjslOltrs%3D
    • Rini BI, Campbell SC, Escudier B. Renal cell carcinoma. Lancet. 2009;373:1119–32.
    • (2009) Lancet , vol.373 , pp. 1119-1132
    • Rini, B.I.1    Campbell, S.C.2    Escudier, B.3
  • 5
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • PID: 22437870, COI: 1:CAS:528:DC%2BC38XksVegtrw%3D
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012;12:252–64.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 6
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • PID: 22658128, COI: 1:CAS:528:DC%2BC38XhtV2rsbnJ
    • Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366:2455–65.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3    Hwu, W.J.4    Topalian, S.L.5    Hwu, P.6
  • 8
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion
    • PID: 12091876, COI: 1:CAS:528:DC%2BD38Xls12msLo%3D
    • Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med. 2002;8:793–800.
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3    Tamura, H.4    Hirano, F.5    Flies, D.B.6
  • 9
    • 84905083767 scopus 로고    scopus 로고
    • PD-1 as an emerging therapeutic target in renal cell carcinoma: current evidence
    • PID: 25114573, COI: 1:CAS:528:DC%2BC2cXhvFaisbfL
    • Tykodi SS. PD-1 as an emerging therapeutic target in renal cell carcinoma: current evidence. Onco Targets Ther. 2014;7:1349–59.
    • (2014) Onco Targets Ther , vol.7 , pp. 1349-1359
    • Tykodi, S.S.1
  • 10
    • 84905982850 scopus 로고    scopus 로고
    • Inducible expression of B7-H1 (PD-L1) and its selective role in tumor site immune modulation
    • PID: 25098285, COI: 1:CAS:528:DC%2BC2cXhtlaks7%2FE
    • Sanmamed MF, Chen L. Inducible expression of B7-H1 (PD-L1) and its selective role in tumor site immune modulation. Cancer J. 2014;20:256–61.
    • (2014) Cancer J , vol.20 , pp. 256-261
    • Sanmamed, M.F.1    Chen, L.2
  • 11
    • 84859158384 scopus 로고    scopus 로고
    • Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
    • PID: 22236695, COI: 1:CAS:528:DC%2BC38XltValu7o%3D
    • Topalian SL, Drake CG, Pardoll DM. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol. 2012;24:207–12.
    • (2012) Curr Opin Immunol , vol.24 , pp. 207-212
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 12
    • 33846852187 scopus 로고    scopus 로고
    • Implications of B7-H1 expression in clear cell carcinoma of the kidney for prognostication and therapy
    • PID: 17255298, COI: 1:CAS:528:DC%2BD2sXoslSqsw%3D%3D
    • Thompson RH, Dong H, Kwon ED. Implications of B7-H1 expression in clear cell carcinoma of the kidney for prognostication and therapy. Clin Cancer Res. 2007;13:709s–15s.
    • (2007) Clin Cancer Res , vol.13 , pp. 709-715
    • Thompson, R.H.1    Dong, H.2    Kwon, E.D.3
  • 13
    • 33645736792 scopus 로고    scopus 로고
    • Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
    • PID: 16585157, COI: 1:CAS:528:DC%2BD28XjtVOkt7w%3D
    • Thompson RH, Kuntz SM, Leibovich BC, Dong H, Lohse CM, Webster WS, et al. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res. 2006;66:3381–5.
    • (2006) Cancer Res , vol.66 , pp. 3381-3385
    • Thompson, R.H.1    Kuntz, S.M.2    Leibovich, B.C.3    Dong, H.4    Lohse, C.M.5    Webster, W.S.6
  • 14
    • 84984919880 scopus 로고    scopus 로고
    • PD-L1 expression in nonclear-cell renal cell carcinoma
    • PID: 25193987, COI: 1:STN:280:DC%2BC2M%2Fos1Ohsg%3D%3D
    • Choueiri TK, Fay AP, Gray KP, Callea M, Ho TH, Albiges L, et al. PD-L1 expression in nonclear-cell renal cell carcinoma. Ann Oncol. 2014;25:2178–84.
    • (2014) Ann Oncol , vol.25 , pp. 2178-2184
    • Choueiri, T.K.1    Fay, A.P.2    Gray, K.P.3    Callea, M.4    Ho, T.H.5    Albiges, L.6
  • 15
    • 77955018897 scopus 로고    scopus 로고
    • PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1
    • PID: 20587542, COI: 1:CAS:528:DC%2BC3cXpt1Oit74%3D
    • Ghiotto M, Gauthier L, Serriari N, Pastor S, Truneh A, Nunès J, et al. PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1. Int Immunol. 2010;22:651–60.
    • (2010) Int Immunol , vol.22 , pp. 651-660
    • Ghiotto, M.1    Gauthier, L.2    Serriari, N.3    Pastor, S.4    Truneh, A.5    Nunès, J.6
  • 16
    • 84890020587 scopus 로고    scopus 로고
    • Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors
    • PID: 24078774, COI: 1:CAS:528:DC%2BC3sXhvV2rtL3J
    • Akbay EA, Koyama S, Carretero J, Altabef A, Tchaicha JH, Christensen C, et al. Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors. Cancer Discov. 2013;3:1355–63.
    • (2013) Cancer Discov , vol.3 , pp. 1355-1363
    • Akbay, E.A.1    Koyama, S.2    Carretero, J.3    Altabef, A.4    Tchaicha, J.H.5    Christensen, C.6
  • 17
    • 33846118474 scopus 로고    scopus 로고
    • Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
    • PID: 17159987, COI: 1:CAS:528:DC%2BD2sXhvFWjtQ%3D%3D
    • Parsa AT, Waldron JS, Panner A, Crane CA, Parney IF, Barry JJ, et al. Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med. 2007;13:84–8.
    • (2007) Nat Med , vol.13 , pp. 84-88
    • Parsa, A.T.1    Waldron, J.S.2    Panner, A.3    Crane, C.A.4    Parney, I.F.5    Barry, J.J.6
  • 18
    • 58549102319 scopus 로고    scopus 로고
    • Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)
    • PID: 19088198, COI: 1:CAS:528:DC%2BD1MXksFSntw%3D%3D
    • Marzec M, Zhang Q, Goradia A, Raghunath PN, Liu X, Paessler M, et al. Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1). Proc Natl Acad Sci U S A. 2008;105:20852–7.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 20852-20857
    • Marzec, M.1    Zhang, Q.2    Goradia, A.3    Raghunath, P.N.4    Liu, X.5    Paessler, M.6
  • 20
    • 67149120530 scopus 로고    scopus 로고
    • Advances and controversies in grading and staging of renal cell carcinoma
    • PID: 19494851
    • Delahunt B. Advances and controversies in grading and staging of renal cell carcinoma. Mod Pathol. 2009;22 Suppl 2:S24–36.
    • (2009) Mod Pathol , vol.22 , pp. 24-36
    • Delahunt, B.1
  • 21
    • 10344220548 scopus 로고    scopus 로고
    • Costimulatory B7-H1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target
    • PID: 15569934, COI: 1:CAS:528:DC%2BD2cXhtFagu7fM
    • Thompson RH, Gillett MD, Cheville JC, Lohse CM, Dong H, Webster WS, et al. Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. Proc Natl Acad Sci U S A. 2004;101:17174–9.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17174-17179
    • Thompson, R.H.1    Gillett, M.D.2    Cheville, J.C.3    Lohse, C.M.4    Dong, H.5    Webster, W.S.6
  • 22
    • 84925969185 scopus 로고    scopus 로고
    • Correlation of PD-L1 tumor expression and treatment outcomes in patients with renal cell carcinoma receiving sunitinib or pazopanib: results from COMPARZ, a randomized controlled trial
    • PID: 25538263, COI: 1:CAS:528:DC%2BC2MXjsF2itLw%3D
    • Choueiri TK, Figueroa DJ, Fay AP, Signoretti S, Liu Y, Gagnon R, et al. Correlation of PD-L1 tumor expression and treatment outcomes in patients with renal cell carcinoma receiving sunitinib or pazopanib: results from COMPARZ, a randomized controlled trial. Clin Cancer Res. 2015;21:1071–7.
    • (2015) Clin Cancer Res , vol.21 , pp. 1071-1077
    • Choueiri, T.K.1    Figueroa, D.J.2    Fay, A.P.3    Signoretti, S.4    Liu, Y.5    Gagnon, R.6
  • 23
    • 27644562256 scopus 로고    scopus 로고
    • Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma
    • PID: 16208700, COI: 1:CAS:528:DC%2BD2MXht1Clu7fP
    • Thompson RH, Gillett MD, Cheville JC, Lohse CM, Dong H, Webster WS, et al. Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma. Cancer. 2005;104:2084–91.
    • (2005) Cancer , vol.104 , pp. 2084-2091
    • Thompson, R.H.1    Gillett, M.D.2    Cheville, J.C.3    Lohse, C.M.4    Dong, H.5    Webster, S.6
  • 24
    • 20244384862 scopus 로고    scopus 로고
    • Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer
    • PID: 15837746, COI: 1:CAS:528:DC%2BD2MXjtlejt7k%3D
    • Ohigashi Y, Sho M, Yamada Y, Tsurui Y, Hamada K, Ikeda N, et al. Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer. Clin Cancer Res. 2005;11:2947–53.
    • (2005) Clin Cancer Res , vol.11 , pp. 2947-2953
    • Ohigashi, Y.1    Sho, M.2    Yamada, Y.3    Tsurui, Y.4    Hamada, K.5    Ikeda, N.6
  • 25
    • 3142721882 scopus 로고    scopus 로고
    • Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity
    • PID: 15256470, COI: 1:CAS:528:DC%2BD2cXls1Omt70%3D
    • Radhakrishnan S, Nguyen LT, Ciric B, Flies D, Van Keulen VP, Tamada K, et al. Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity. Cancer Res. 2004;64:4965–72.
    • (2004) Cancer Res , vol.64 , pp. 4965-4972
    • Radhakrishnan, S.1    Nguyen, L.T.2    Ciric, B.3    Flies, D.4    Van Keulen, V.P.5    Tamada, K.6
  • 27
    • 78649479185 scopus 로고    scopus 로고
    • siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells
    • PID: 20682852, COI: 1:CAS:528:DC%2BC3cXhsFGgtbvM
    • Hobo W, Maas F, Adisty N, de Witte T, Schaap N, van der Voort R, et al. siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells. Blood. 2010;116:4501–11.
    • (2010) Blood , vol.116 , pp. 4501-4511
    • Hobo, W.1    Maas, F.2    Adisty, N.3    de Witte, T.4    Schaap, N.5    van der Voort, R.6
  • 28
    • 84873336707 scopus 로고    scopus 로고
    • The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition
    • PID: 23095323, COI: 1:CAS:528:DC%2BC3sXitVOht7Y%3D
    • Jiang X, Zhou J, Giobbie-Hurder A, Wargo J, Hodi FS. The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3 K inhibition. Clin Cancer Res. 2013;19:598–609.
    • (2013) Clin Cancer Res , vol.19 , pp. 598-609
    • Jiang, X.1    Zhou, J.2    Giobbie-Hurder, A.3    Wargo, J.4    Hodi, F.S.5
  • 29
    • 84899753178 scopus 로고    scopus 로고
    • PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
    • PID: 24778419, COI: 1:CAS:528:DC%2BC2cXotVCjs7w%3D
    • Noman MZ, Desantis G, Janji B, Hasmim M, Karray S, Dessen P, et al. PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation. J Exp Med. 2014;211:781–90.
    • (2014) J Exp Med , vol.211 , pp. 781-790
    • Noman, M.Z.1    Desantis, G.2    Janji, B.3    Hasmim, M.4    Karray, S.5    Dessen, P.6
  • 30
    • 84893872087 scopus 로고    scopus 로고
    • A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells
    • PID: 24336068, COI: 1:CAS:528:DC%2BC2cXhvVSmsr4%3D
    • Barsoum IB, Smallwood CA, Siemens DR, Graham CH. A mechanism of hypoxia-mediated escape from adaptive immunity in cancer cells. Cancer Res. 2014;74:665–74.
    • (2014) Cancer Res , vol.74 , pp. 665-674
    • Barsoum, I.B.1    Smallwood, C.A.2    Siemens, D.R.3    Graham, C.H.4


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