MiRNAs in Urine Extracellular Vesicles as Predictors of Early-Stage Diabetic Nephropathy

Journal of Diabetes Research

Volumn 2016, Issue , 2016, Pages

  Jia, Yijie ^a   Guan, Meiping ^a   Zheng, Zongji ^a   Zhang, Qian ^a   Tang, Chuan ^a   Xu, Wenwei ^a   Xiao, Zhizhou ^a   Wang, Ling ^a   Xue, Yaoming ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; MICRORNA; MICRORNA 192; MICRORNA 194; MICRORNA 215; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CREATININE; MIRN192 MICRORNA, HUMAN; MIRN194 MICRORNA, HUMAN; MIRN215 MICRORNA, HUMAN; TGFB1 PROTEIN, HUMAN;

ADULT; ALBUMINURIA; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; EXOSOME; FEMALE; HUMAN; HUMAN CELL; KIDNEY TUBULE EPITHELIUM; MACROALBUMINURIA; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; ANALYSIS; CASE CONTROL STUDY; COMPLICATION; GLUCOSE BLOOD LEVEL; KIDNEY TUBULE; METABOLISM; MIDDLE AGED; RECEIVER OPERATING CHARACTERISTIC; URINE;

ALBUMINURIA; BIOMARKERS; BLOOD GLUCOSE; CASE-CONTROL STUDIES; CREATININE; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; EXTRACELLULAR VESICLES; FEMALE; HUMANS; KIDNEY TUBULES; MALE; MICRORNAS; MIDDLE AGED; ROC CURVE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84958073604     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2016/7932765     Document Type: Article

References (42)

1. H.-H. Parving, H. Lehnert, J. Brochner-Mortensen, R. Gomis, S. Andersen, and P. Arner, "The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes," The New England Journal of Medicine, vol. 345, no. 12, pp. 870-878, 2001.
2. C. E. Mogensen, C. K. Christensen, and E. Vittinghus, "The stages in diabetic renal disease. With emphasis on the stage of incipient diabetic nephropathy," Diabetes, vol. 32, supplement 2, pp. 64-78, 1983.
3. N. A. Wahab, L. Schaefer, B. S. Weston et al., "Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli," Diabetologia, vol. 48, no. 12, pp. 2650-2660, 2005.
4. G. L. Bakris, "Recognition, pathogenesis, and treatment of different stages of nephropathy in patients with type 2 diabetes mellitus," Mayo Clinic Proceedings, vol. 86, no. 5, pp. 444-456, 2011.
5. Y. K. Kim, "Extracellular microRNAs as biomarkers in human disease," Chonnam Medical Journal, vol. 51, no. 2, pp. 51-57, 2015.
6. B. Zhou, Z. Li, H. Yang, and N. He, "Extracellular miRNAs: origin, function and biomarkers in hepatic diseases," Journal of Biomedical Nanotechnology, vol. 10, no. 10, pp. 2865-2890, 2014.
7. Y. Sun, S. Koo, N. White et al., "Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs," Nucleic Acids Research, vol. 32, no. 22, article e188, 2004.
8. H. W. Z. Khella, M. Bakhet, G. Allo et al., "Mir-192, mir-194 and mir-215: a convergent microrna network suppressing tumor progression in renal cell carcinoma," Carcinogenesis, vol. 34, no. 10, pp. 2231-2239, 2013.
9. J. Mu, Q. Pang, Y.-H. Guo et al., "Functional implications of microrna-215 in TGF-β1-induced phenotypic transition of mesangial cells by targeting CTNNBIP1," PLoS ONE, vol. 8, no. 3, Article ID e58622, 2013.
10. Y. Q. Chen, X. X. Wang, X. M. Yao et al., "Abated microRNA-195 expression protected mesangial cells from apoptosis in early diabetic renal injury in mice," Journal of Nephrology, vol. 25, no. 4, pp. 566-576, 2012.
11. J. Perez-Hernandez and R. Cortes, "Extracellular vesicles as biomarkers of systemic lupus erythematosus," Disease Markers, vol. 2015, Article ID 613536, 7 pages, 2015.
12. A. Lo Cicero, P. D. Stahl, and G. Raposo, "Extracellular vesicles shuffling intercellular messages: for good or for bad," Current Opinion in Cell Biology, vol. 35, pp. 69-77, 2015.
13. J. Qin and Q. Xu, "Functions and applications of exosomes," Acta Poloniae Pharmaceutica - Drug Research, vol. 71, no. 4, pp. 537-543, 2014.
14. M. Salih, R. Zietse, and E. J. Hoorn, "Urinary extracellular vesicles and the kidney: biomarkers and beyond," The American Journal of Physiology - Renal Physiology, vol. 306, no. 11, pp. F1251-F1259, 2014.
15. M. Colombo, G. Raposo, and C. Théry, "Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles," Annual Review of Cell and Developmental Biology, vol. 30, no. 1, pp. 255-289, 2014.
16. L. Musante, D. E. Tataruch, and H. Holthofer, "Use and isolation of urinary exosomes as biomarkers for diabetic nephropathy," Frontiers in Endocrinology, vol. 5, article 149, 2014.
17. L. Musante, D. Tataruch, D. Gu et al., "Proteases and protease inhibitors of urinary extracellular vesicles in diabetic nephropathy," Journal of Diabetes Research, vol. 2015, Article ID 289734, 14 pages, 2015.
18. L.-L. Lv, Y.-H. Cao, H.-F. Ni et al., "MicroRNA-29c in urinary exosome/microvesicle as a biomarker of renal fibrosis," The American Journal of Physiology - Renal Physiology, vol. 305, no. 8, pp. F1220-F1227, 2013.
19. C. Solé, J. Cortés-Hernández, M. L. Felip, M. Vidal, and J. Ordi-Ros, "miR-29c in urinary exosomes as predictor of early renal fibrosis in lupus nephritis," Nephrology Dialysis Transplantation, vol. 30, no. 9, pp. 1488-1496, 2015.
20. H. W. King, M. Z. Michael, and J. M. Gleadle, "Hypoxic enhancement of exosome release by breast cancer cells," BMC Cancer, vol. 12, article 421, 2012.
21. P. S. Mitchell, R. K. Parkin, E. M. Kroh et al., "Circulating microRNAs as stable blood-based markers for cancer detection," Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 30, pp. 10513-10518, 2008.
22. L.-L. Lv, Y.-H. Cao, M.-M. Pan et al., "CD2AP mRNA in urinary exosome as biomarker of kidney disease," Clinica Chimica Acta, vol. 428, pp. 26-31, 2014.
23. C. Eichelser, I. Stückrath, V. Müller et al., "Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients," Oncotarget, vol. 5, no. 20, pp. 9650-9663, 2014.
24. M. Kato and R. Natarajan, "Diabetic nephropathy - emerging epigenetic mechanisms," Nature Reviews Nephrology, vol. 10, no. 9, pp. 517-530, 2014.
25. H. Wu, L. Kong, S. Zhou et al., "The role of micrornas in diabetic nephropathy," Journal of Diabetes Research, vol. 2014, Article ID 920134, 12 pages, 2014.
26. J. Perez-Hernandez, M. J. Forner, C. Pinto et al., "Increased urinary exosomal micrornas in patients with systemic lupus erythematosus," PLoS ONE, vol. 10, no. 9, Article ID e0138618, 2015.
27. S. Saal and S. J. Harvey, "MicroRNAs and the kidney: coming of age," Current Opinion in Nephrology and Hypertension, vol. 18, no. 4, pp. 317-323, 2009.
28. N. Kito, K. Endo, M. Ikesue, H. Weng, and N. Iwai, "miRNA profiles of tubular cells: diagnosis of kidney injury," BioMed Research International, vol. 2015, Article ID 465479, 9 pages, 2015.
29. H. Peng, M. Zhong, W. Zhao et al., "Urinary miR-29 correlates with albuminuria and carotid intima-media thickness in type 2 diabetes patients," PLoS ONE, vol. 8, no. 12, Article ID e82607, 2013.
30. F. Barutta, M. Tricarico, A. Corbelli et al., "Urinary exosomal MicroRNAs in incipient diabetic nephropathy," PLoS ONE, vol. 8, no. 11, Article ID e73798, 2013.
31. C. S. Neal, M. Z. Michael, L. K. Pimlott, T. Y. Yong, J. Y. Z. Li, and J. M. Gleadle, "Circulating microRNA expression is reduced in chronic kidney disease," Nephrology Dialysis Transplantation, vol. 26, no. 11, pp. 3794-3802, 2011.
32. H. Wu, L. Kong, S. Zhou et al., "The role of micrornas in diabetic nephropathy," Journal of Diabetes Research, vol. 2014, Article ID 920134, 12 pages, 2014.
33. Y. Yang, L. Xiao, J. Li, Y. S. Kanwar, F. Liu, and L. Sun, "Urine miRNAs: potential biomarkers for monitoring progression of early stages of diabetic nephropathy," Medical Hypotheses, vol. 81, no. 2, pp. 274-278, 2013.
34. A. Krupa, R. Jenkins, D. D. Luo, A. Lewis, A. Phillips, and D. Fraser, "Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy," Journal of the American Society of Nephrology, vol. 21, no. 3, pp. 438-447, 2010.
35. M. Hanke, K. Hoefig, H. Merz et al., "A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer," Urologic Oncology, vol. 28, no. 6, pp. 655-661, 2010.
36. A. C. Chung and H. Y. Lan, "MicroRNAs in renal fibrosis," Frontiers in Physiology, vol. 6, article 50, 2015.
37. S. Ibrahim and L. Rashed, "Estimation of transforming growth factor-beta 1 as a marker of renal injury in type II diabetes mellitus," Saudi Medical Journal, vol. 28, no. 4, pp. 519-523, 2007.
38. P. Trnka, L. Ivanova, M. J. Hiatt, and D. G. Matsell, "Urinary biomarkers in obstructive nephropathy," Clinical Journal of the American Society of Nephrology, vol. 7, no. 10, pp. 1567-1575, 2012.
39. M. Kato, J. Zhang, M. Wang et al., "MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-β-induced collagen expression via inhibition of E-box repressors," Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 9, pp. 3432-3437, 2007.
40. M. Kato, L. Arce, M. Wang, S. Putta, L. Lanting, and R. Natarajan, "A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells," Kidney International, vol. 80, no. 4, pp. 358-368, 2011.
41. J. Zhang, S. Li, L. Li et al., "Exosome and exosomal microrna: trafficking, sorting, and function," Genomics, Proteomics & Bioinformatics, vol. 13, no. 1, pp. 17-24, 2015.
42. B. Wang, M. Herman-Edelstein, P. Koh et al., "E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-β," Diabetes, vol. 59, no. 7, pp. 1794-1802, 2010.