Effects of various antimicrobial stewardship programs on antimicrobial usage and resistance among common gram-negative bacilli causing health care-associated infections: A multicenter comparison

Journal of Microbiology, Immunology and Infection

Volumn 49, Issue 1, 2016, Pages 74-82

  Lai, Chung Chih ^a   Shi, Zhi Yuan ^b,c   Chen, Yen Hsu ^a,d,e   Wang, Fu Der ^c,f  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^f TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Antibiotic consumption; Antibiotic stewardship program; Carbapenem; Gram negative organisms; Multidrug resistant organisms

Indexed keywords

ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE INHIBITOR; CARBAPENEM; CARBAPENEM DERIVATIVE; CEFEPIME; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; PIPERACILLIN PLUS TAZOBACTAM; POLYPEPTIDE ANTIBIOTIC AGENT; QUINOLONE DERIVATIVE; TIGECYCLINE; ANTIINFECTIVE AGENT;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ANTIMICROBIAL STEWARDSHIP PROGRAM; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; DRUG EFFICACY; DRUG USE; GRAM NEGATIVE BACTERIUM; HEALTH PROGRAM; HEALTHCARE ASSOCIATED INFECTION; HOSPITAL; HUMAN; INFECTION CONTROL; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PRESCRIPTION; PSEUDOMONAS AERUGINOSA; RETROSPECTIVE STUDY; TAIWAN; CLINICAL TRIAL; CROSS INFECTION; DRUG EFFECTS; DRUG UTILIZATION; GRAM-NEGATIVE BACTERIAL INFECTIONS; HEALTH CARE POLICY; ISOLATION AND PURIFICATION; MICROBIOLOGY; ORGANIZATIONAL POLICY; PREVALENCE; STANDARDS;

ANTI-BACTERIAL AGENTS; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; DRUG UTILIZATION; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HEALTH POLICY; HOSPITALS; HUMANS; ORGANIZATIONAL POLICY; PREVALENCE; RETROSPECTIVE STUDIES; TAIWAN;

EID: 84958061022     PISSN: 16841182     EISSN: 19959133     Source Type: Journal    
DOI: 10.1016/j.jmii.2015.05.011     Document Type: Article

References (38)

1. Jean S.S., Lee W.S., Bai K.J., Lam C., Hsu C.W., Yu K.W., et al. Relationship between the distribution of cefepime minimum inhibitory concentrations and detection of extended-spectrum β-lactamase production among clinically important Enterobacteriaceae isolates obtained from patients in intensive care units in Taiwan: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) in 2007. J Microbiol Immunol Infect 2015, 48:85-91.
2. Chen I.L., Lee C.H., Su L.H., Tang Y.F., Chang S.J., Liu J.W. Antibiotic consumption and healthcare-associated infections caused by multidrug-resistant gram-negative bacilli at a large medical center in Taiwan from 2002 to 2009: implicating the importance of antibiotic stewardship. PLoS One 2013, 8:e65621.
3. McGowan J.E. Antimicrobial stewardship-the state of the art in 2011: focus on outcome and methods. Infect Control Hosp Epidemiol 2012, 33:331-337.
4. Tseng S.H., Ke Y.F., Chang F.Y. National action plan to combat antimicrobial resistance in Taiwan. J Microbiol Immunol Infect 2014, 47:167-170.
5. Cook P.P., Catrou P.G., Christie J.D., Young P.D., Polk R.E. Reduction in broad-spectrum antimicrobial use associated with no improvement in hospital antibiogram. J Antimicrob Chemother 2004, 53:853-859.
6. Ohl C.A., Dodds Ashley E.S. Antimicrobial stewardship programs in community hospitals: the evidence base and case studies. Clin Infect Dis 2011, 531:S23-S28.
7. Lai C.C., Wang C.Y., Chu C.C., Tan C.K., Lu C.L., Lee Y.C., et al. Correlation between antibiotic consumption and resistance of Gram-negative bacteria causing healthcare-associated infections at a university hospital in Taiwan from 2000 to 2009. J Antimicrob Chemother 2011, 66:1374-1382.
8. Lai C.C., Wang C.Y., Chu C.C., Tan C.K., Lu C.L., Lee Y.L., et al. Correlation between antimicrobial consumption and resistance among Staphylococcus aureus and enterococci causing healthcare-associated infections at a university hospital in Taiwan from 2000 to 2009. Eur J Clin Microbiol Infect Dis 2011, 30:265-271.
9. Troughton J.A., Millar G., Smyth E.T., Doherty L., McMullan R. Ciprofloxacin use and susceptibility of Gram-negative organisms to quinolone and non-quinolone antibiotics. J Antimicrob Chemother 2011, 66:2152-2158.
10. Ho C.M., Ho M.W., Liu Y.C., Toh H.S., Lee Y.L., Liu Y.M., et al. Correlation between carbapenem consumption and resistance to carbapenems among Enterobacteriaceae isolates collected from patients with intra-abdominal infections at five medical centers in Taiwan, 2006-2010. Int J Antimicrob Agents 2012, 40:S24-S28.
11. Cheng A., Tan C.K., Chu C.C., Huang Y.T., Liao C.H., Sheng W.H., et al. Fluoroquinolone use and resistance of Gram-negative bacteria causing healthcare-associated infections at a university hospital in Taiwan from 2000 to 2008. J Infect 2012, 64:618-620.
12. Hsu L.Y., Tan T.Y., Tam V.H., Kwa A., Fisher D.A., Koh T.H., et al. Surveillance and correlation of antibiotic prescription and resistance of Gram-negative bacteria in Singaporean hospitals. Antimicrob Agents Chemother 2010, 54:1173-1178.
13. Weng T.C., Chen Y.H., Lee C.C., Wang C.Y., Lai C.C., Tang H.J., et al. Correlation between fluoroquinolone consumption in hospitals and ciprofloxacin resistance amongst Pseudomonas aeruginosa isolates causing healthcare-associated infections, Taiwan, 2000-2009. Int J Antimicrob Agents 2011, 37:581-584.
14. Polk R.E., Johnson C.K., McClish D., Wenzel R.P., Edmond M.B. Predicting hospital rates of fluoroquinolone-resistant Pseudomonas aeruginosa from fluoroquinolone use in US hospitals and their surrounding communities. Clin Infect Dis 2004, 39:497-503.
15. White R.L., Friedrich L.V., Mihm L.B., Bosso J.A. Assessment of the relationship between antimicrobial usage and susceptibility: differences between the hospital and specific patient-care areas. Clin Infect Dis 2000, 31:16-23.
16. Neuhauser M.M., Weinstein R.A., Rydman R., Danziger L.H., Karam G., Quinn J.P. Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use. JAMA 2003, 289:885-888.
17. Lee Y.J., Liu H.Y., Lin Y.C., Sun K.L., Chun C.L., Hsueh P.R. Fluoroquinolone resistance of Pseudomonas aeruginosa isolates causing nosocomial infection is correlated with levofloxacin but not ciprofloxacin use. Int J Antimicrob Agents 2010, 35:261-264.
18. Monnet D.L., Archibald L.K., Phillips L., Tenover F.C., McGowan J.E., Gaynes R.P. Antimicrobial use and resistance in eight US hospitals: complexities of analysis and modeling. Intensive Care Antimicrobial Resistance Epidemiology Project and National Nosocomial Infections Surveillance System Hospitals. Infect Control Hosp Epidemiol 1998, 19:388-394.
19. Carling P.C., Fung T., Coldiron J.S. Parenteral antibiotic use in acute-care hospitals: a standardized analysis of fourteen institutions. Clin Infect Dis 1999, 29:1189-1196.
20. Tseng S.H., Chien L.J., Chang F.Y. National action plan to eliminate central line-associated bloodstream infections in Taiwan. J Microbiol Immunol Infect 2014, 47:265-267.
21. Horan T.C., Andrus M., Dudeck M.A. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008, 36:309-332.
22. Clinical and Laboratory Standards Institute Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically 2009, Document M07-A8, CLSI, Wayne, PA.
23. Hsueh P.R., Ko W.C., Wu J.J., Lu J.J., Wang F.D., Wu H.Y., et al. Consensus statement on the adherence to Clinical and Laboratory Standards Institute (CLSI) Antimicrobial Susceptibility Testing Guidelines (CLSI-2010 and CLSI-2010-update) for Enterobacteriaceae in clinical microbiology laboratories in Taiwan. J Microbiol Immunol Infect 2010, 43:452-455.
24. Dellit T.H., Owens R.C., McGowan J.E., Gerding D.N., Weinstein R.A., Burke J.P., et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 2007, 44:159-177.
25. LaRosa L.A., Fishman N.O., Lautenbach E., Koppel R.J., Morales K.H., Linkin D.R. Evaluation of antimicrobial therapy orders circumventing an antimicrobial stewardship program: investigating the strategy of "stealth dosing". Infect Control Hosp Epidemiol 2007, 28:551-556.
26. Griffith M., Postelnick M., Scheetz M. Antimicrobial stewardship programs: methods of operation and suggested outcomes. Expert Rev Anti Infect Ther 2012, 10:63-73.
27. Kaki R., Elligsen M., Walker S., Simor A., Palmay L., Daneman N. Impact of antimicrobial stewardship in critical care: a systematic review. J Antimicrob Chemother 2011, 66:1223-1230.
28. Stone S.P., Cooper B.S., Kibbler C.C., Cookson B.D., Roberts J.A., Medley G.F., et al. The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection. J Antimicrob Chemother 2007, 59:833-840.
29. Shardell M., Harris A.D., El-Kamary S.S., Furuno J.P., Miller R.R., Perencevich E.N. Statistical analysis and application of quasi experiments to antimicrobial resistance intervention studies. Clin Infect Dis 2007, 45:901-907.
30. Jarlier V., Trystram D., Brun-Buisson C., Fournier S., Carbonne A., Marty L., et al. Curbing methicillin-resistant Staphylococcus aureus in 38 French hospitals through a 15-year institutional control program. Arch Intern Med 2010, 170:552-559.
31. Lafaurie M., Porcher R., Donay J.L., Touratier S., Molina J.M. Reduction of fluoroquinolone use is associated with a decrease in methicillin-resistant Staphylococcus aureus and fluoroquinolone-resistant Pseudomonas aeruginosa isolation rates: a 10 year study. J Antimicrob Chemother 2012, 67:1010-1015.
32. Gales A.C., Jones R.N., Sader H.S. Contemporary activity of colistin and polymyxin B against a worldwide collection of Gram-negative pathogens: results from the SENTRY Antimicrobial Surveillance Program (2006-09). J Antimicrob Chemother 2011, 66:2070-2074.
33. Su C.H., Wang J.T., Hsiung C.A., Chien L.J., Chi C.L., Yu H.T., et al. Increase of carbapenem-resistant Acinetobacter baumannii infection in acute care hospitals in Taiwan: association with hospital antimicrobial usage. PLoS One 2012, 7:e37788.
34. Ku W.W., Kung C.H., Lee C.H., Tseng C.P., Wu P.F., Kuo S.C., et al. Evolution of carbapenem resistance in Acinetobacter baumannii: an 18-year longitudinal study from a medical center in northern Taiwan. J Microbiol Immunol Infect 2015, 48:57-64.
35. Iosifidis E., Antachopoulos C., Tsivitanidou M., Katragkou A., Farmaki E., Tsiakou M., et al. Differential correlation between rates of antimicrobial drug consumption and prevalence of antimicrobial resistance in a tertiary care hospital in Greece. Infect Control Hosp Epidemiol 2008, 29:615-622.
36. Wenzel R.P., Wong M.T. Managing antibiotic use-impact of infection control. Clin Infect Dis 1999, 28:1126-1127.
37. Turnidge J., Christiansen K. Antibiotic use and resistance-proving the obvious. Lancet 2005, 365:548-549.
38. Liew Y.X., Krishnan P., Yeo C.L., Tan T.Y., Lee S.Y., Lim W.P., et al. Surveillance of broad-spectrum antibiotic prescription in Singaporean hospitals: a 5-year longitudinal study. PLoS One 2011, 6:e28751.