Did the H1N1 vaccine reduce the risk of admission with influenza and pneumonia during the pandemic?

PLoS ONE

Volumn 10, Issue 11, 2015, Pages

  Mahmud, Salaheddin M ^a,b,d   Bozat Emre, Songul ^a,d   Hammond, Gregory ^a   Elliott, Lawrence ^a,b,d   Van Caeseele, Paul ^a,c,d  

^a UNIVERSITY OF MANITOBA   (Canada)

^b WINNIPEG REGIONAL HEALTH AUTHORITY   (Canada)

^c CADHAM PROVINCIAL LABORATORY   (Canada)

^d Manitoba Health   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE; PNEUMOCOCCUS VACCINE; IMMUNOLOGICAL ADJUVANT;

ADOLESCENT; ADULT; AGED; ARTICLE; CANADA; CASE CONTROL STUDY; CHILD; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; INFANT; INFECTION RISK; INFLUENZA; INFLUENZA A; MAJOR CLINICAL STUDY; MALE; MASS IMMUNIZATION; NUMBERS NEEDED TO TREAT; PANDEMIC; PNEUMONIA; RANDOM SAMPLE; REGISTER; RISK REDUCTION; SEASONAL INFLUENZA; IMMUNOLOGY; INFLUENZA A VIRUS (H1N1); INFLUENZA, HUMAN; MANITOBA; MIDDLE AGED; PRESCHOOL CHILD; PREVENTIVE HEALTH SERVICE; RISK; YOUNG ADULT;

ADJUVANTS, IMMUNOLOGIC; ADOLESCENT; ADULT; AGED; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; HOSPITALIZATION; HUMANS; IMMUNIZATION PROGRAMS; INFANT; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA VACCINES; INFLUENZA, HUMAN; MALE; MANITOBA; MIDDLE AGED; PANDEMICS; PATIENT ADMISSION; PNEUMONIA; REGISTRIES; RISK; YOUNG ADULT;

EID: 84957990174     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0142754     Document Type: Article

References (39)

1. Girard MP, Tam JS, Assossou OM, Kieny MP. The 2009 A (H1N1) influenza virus pandemic: A review. Vaccine 2010; 28(31): 4895-902. doi: 10.1016/j.vaccine.2010.05.031 PMID: 20553769
2. Mahmud S, Hammond G, Elliott L, Hilderman T, Kurbis C, Caetano P, et al. Effectiveness of the pandemic H1N1 influenza vaccines against laboratory-confirmed H1N1 infections: Population-based case-control study. Vaccine 2011; 29(45): 7975-81. doi: 10.1016/j.vaccine.2011.08.068 PMID: 21884747
3. Osterholm MT, Kelley NS, Sommer A, Belongia EA. Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis. The Lancet Infectious Diseases 2012; 12(1): 36-44. doi: 10.1016/S1473-3099(11)70295-X PMID: 22032844
4. Jhung MA, Swerdlow D, Olsen SJ, Jernigan D, Biggerstaff M, Kamimoto L, et al. Epidemiology of 2009 Pandemic Influenza A (H1N1) in the United States. Clin Infect Dis 2011; 52(suppl 1): S13-S26. doi: 10.1093/cid/ciq008 PMID: 21342884
5. Singh H, Mahmud SM, Turner D, Xue L, Demers AA, Bernstein CN. Long-term use of statins and risk of colorectal cancer: a population-based study. Am J Gastroenterol 2009; 104(12): 3015-23. doi: 10.1038/ajg.2009.574 PMID: 19809413
6. Roos L, Mustard C, Nicol J, McLerran DF, Malenka DJ, Young TK, et al. Registries and administrative data: organization and accuracy. Med Care 1993; 31(3): 201-12. PMID: 8450678
7. Canadian Institute for Health Information. ICD-10-CA International statistical classification of diseases and related health problems, Tenth Revision: Ottawa, Ontario, Canada, 2009.
8. Canadian Institute for Health Information. Canadian Classification of Health Interventions: Ottawa, Ontario, Canada, 2006.
9. Roberts J, Roos L, Poffenroth L, Poffenroth LA, Hassard TH, Bebchuk JD, Carter AO, et al. Surveillance of vaccine-related adverse events in the first year of life: a Manitoba cohort study. J Clin Epidemiol 1996; 49(1): 51. PMID: 8598511
10. Roberts J, Poffenroth L, Roos L, Bebchuk J, Carter A. Monitoring childhood immunizations: a Canadian approach. Am J Public Health 1994; 84(10): 1666. PMID: 7943493
11. Manitoba H. H1N1 Flu in Manitoba: Manitoba's Response, Lessons Learned. Winnipeg, MB, CAN: Manitoba Health, 2010.
12. Elixhauser A, Steiner C, Harris DR, Coffey RM. Comorbidity measures for use with administrative data. Med Care 1998; 36(1): 8-27. PMID: 9431328
13. Lix L, Yogendran M, Burchill C, Metge C, McKeen N, Moore D, et al. Defining and Validating Chronic Diseases: An Administrative Data Approach. Winnipeg: Manitoba Centre for Health Policy, 2006.
14. Dublin S, Jackson ML, Nelson JC, Weiss NS, Larson EB, Jackson LA. Statin use and risk of community acquired pneumonia in older people: population based case-control study. BMJ 2009; 338: b2137. doi: 10.1136/bmj.b2137 PMID: 19531550
15. Hardy JR, Holford TR, Hall GC, Bracken MB. Strategies for identifying pregnancies in the automated medical records of the General Practice Research Database. Pharmacoepidemiol Drug Saf 2004; 13 (11): 749-59. PMID: 15386720
16. Quan H, Parsons GA, Ghali WA. Validity of information on comorbidity derived rom ICD-9-CCM administrative data. Med Care 2002; 40(8): 675-85. PMID: 12187181
17. Kozyrskyj AL, Mustard CA. Validation of an electronic, population-based prescription database. Ann Pharmacother 1998; 32(11): 1152-7. PMID: 9825079
18. Le Blanc J, Li Y, Bastien N, Forward K, Davidson R, Hatchette T. Switching gears for an influenza pandemic: validation of a duplex reverse transcriptase PCR assay for simultaneous detection and confirmatory identification of pandemic (H1N1) 2009 influenza virus. J Clin Microbiol 2009; 47(12): 3805. doi: 10.1128/JCM.01344-09 PMID: 19794033
19. Bridges CB, Katz JM, Levandowski RA, Cox NJ. Influenza Vaccine (Inactivated). In: Plotkin S, Orenstein W, Offit P. Vaccines: Elsevier, 2008:259-90.
20. Clayton D, Hills M. Statistical models in epidemiology. Oxford; New York: Oxford University Press, 1993.
21. Gilmour H, Hofmann N. H1N1 vaccination. Health Rep Vol. 21: Statistics Canada, Catalogue no. 82-003-XPE, 2010
22. Yin JK, Khandaker G, Rashid H, Heron L, Ridda I, Booy R. Immunogenicity and safety of pandemic influenza A (H1N1) 2009 vaccine: systematic review and meta-analysis. Influenza Other Respir Viruses 2011; 5(5): 299-305. doi: 10.1111/j.1750-2659.2011.00229.x PMID: 21668694
23. Manzoli L, De Vito C, Salanti G, D'Addario M, Villari P, Ioannidis JPA. Meta-Analysis of the Immunogenicity and Tolerability of Pandemic Influenza A 2009 (H1N1) Vaccines. PLoS ONE 2011; 6(9): e24384. doi: 10.1371/journal.pone.0024384 PMID: 21915319
24. Manzoli L, Ioannidis JP, Flacco ME, De Vito C, Villari P. Effectiveness and harms of seasonal and pandemic influenza vaccines in children, adults and elderly: a critical review and re-analysis of 15 metaanalyses. Hum Vaccin Immunother 2012; 8(7): 851-62. doi: 10.4161/hv.19917 PMID: 22777099
25. Simpson CR, Ritchie LD, Robertson C, Sheikh A, McMenamin J. Vaccine effectiveness in pandemic influenza-primary care reporting (VIPER): an observational study to assess the effectiveness of the pandemic influenza A (H1N1)v vaccine. Health Technol Assess 2010; 14(34): 313-46. doi: 10.3310/hta14340-05 PMID: 20630126
26. Emborg HD, Krause TG, Hviid A, Simonsen J, Molbak K. Effectiveness of vaccine against pandemic influenza A/H1N1 among people with underlying chronic diseases: cohort study, Denmark, 2009-10. BMJ 2012; 344: d7901.
27. Steens A, Wijnans EG, Dieleman JP, Sturkenboom MC, van der Sande MA, van der Hoek W. Effectiveness of a MF-59-adjuvanted pandemic influenza vaccine to prevent 2009 A/H1N1 influenza-related hospitalisation; a matched case-control study. BMC Infect Dis 2011; 11: 196. doi: 10.1186/1471-2334-11-196 PMID: 21767348
28. Mahmud SM, Becker M, Keynan Y, Elliot L, Thompson LH, Fowke K, et al. Estimated cumulative incidence of pandemic (H1N1) influenza among pregnant women during the first wave of the 2009 pandemic. CMAJ 2010; 182(14): 1522-4. doi: 10.1503/cmaj.100488 PMID: 20823167
29. Thompson LH, Mahmud SM, Keynan Y, Blanchard JF, Slater J, Dawood M, et al. Serological survey of the novel influenza A H1N1 in inner city Winnipeg, Manitoba, 2009. Canadian Journal of Infectious Diseases and Medical Microbiology 2012; 23(2): 65-70. PMID: 23730311
30. Gilca R, Deceuninck G, De Serres G, Boulianne N, Sauvageau C, Quach C, et al. Effectiveness of pandemic H1N1 vaccine against influenza-related hospitalization in children. Pediatrics 2011; 128(5): e1084-91. doi: 10.1542/peds.2010-3492 PMID: 21987710
31. Hadler JL, Baker TN, Papadouka V, France AM, Zimmerman C, Livingston KA, et al. Effectiveness of 1 dose of 2009 influenza A (H1N1) vaccine at preventing hospitalization with pandemic H1N1 influenza in children aged 7 months-9 years. J Infect Dis 2012; 206(1): 49-55. doi: 10.1093/infdis/jis306 PMID: 22551808
32. Jefferson T, Di Pietrantonj C, Al-Ansary LA, Ferroni E, Thorning S, Thomas RE. Vaccines for preventing influenza in the elderly. The Cochrane database of systematic reviews 2010; (2:): CD004876. doi: 10.1002/14651858.CD004876.pub3 PMID: 20166072
33. Baxter R, Lee J, Fireman B. Evidence of Bias in Studies of Influenza Vaccine Effectiveness in Elderly Patients. J Infect Dis 2010; 201(2): 186-9. doi: 10.1086/649568 PMID: 19995265
34. Fireman B, Lee J, Lewis N, Bembom O, van der Laan M, Baxter R. Influenza Vaccination and Mortality: Differentiating Vaccine Effects From Bias. Am J Epidemiol 2009; 170(5): 650-6. doi: 10.1093/aje/kwp173 PMID: 19625341
35. Wong K, Campitelli MA, Stukel TA, Kwong JC. Estimating influenza vaccine effectiveness in community-dwelling elderly patients using the instrumental variable analysis method. Arch Intern Med 2012; 172(6): 484-91. doi: 10.1001/archinternmed.2011.2038 PMID: 22371873
36. Mahmud SM, Van Caeseele P, Hammond G, Kurbis C, Hilderman T, Elliott L. No Association between 2008-09 Influenza Vaccine and Influenza A (H1N1) pdm09 Virus Infection, Manitoba, Canada, 2009. Emerg Infect Dis 2012; 18(5): 801. doi: 10.3201/eid1805.111596 PMID: 22516189
37. Psaty BM, Koepsell TD, Lin D, Weiss NS, Siscovick DS, Rosendaal FR, et al. Assessment and control for confounding by indication in observational studies. J Am Geriatr Soc 1999; 47(6): 749-54. PMID: 10366179
38. Viboud C, Simonsen L. Does Seasonal Influenza Vaccination Increase the Risk of Illness with the 2009 A/H1N1 Pandemic Virus? PLoS Med 2010; 7(4): e1000259. doi: 10.1371/journal.pmed.1000259 PMID: 20386730
39. Young T, Roos L, Gelskey D. Estimating the burden of disease: comparing administrative data and self-reports. Med Care 1997; 35(9): 932-47. PMID: 9298082