Risk factors for postoperative delirium following hip fracture repair in elderly patients: a systematic review and meta-analysis

Aging Clinical and Experimental Research

Volumn 29, Issue 2, 2017, Pages 115-126

  Yang, Yanjiang ^a   Zhao, Xin ^c   Dong, Tianhua ^a   Yang, Zongyou ^a   Zhang, Qi ^a   Zhang, Yingze ^a,b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b KEY LABORATORY OF BIOMECHANICS OF HEBEI PROVINCE   (China)

^c HEBEI GENERAL HOSPITAL   (China)

Author keywords

Delirium; Elderly patients; Hip fracture; Postoperative; Risk factors

Indexed keywords

MORPHINE;

AGE; AGED; COGNITIVE DEFECT; DRUG USE; HEART FAILURE; HIP FRACTURE; HIP SURGERY; HUMAN; INCIDENCE; INSTITUTIONAL CARE; POSTOPERATIVE DELIRIUM; PREOPERATIVE PERIOD; QUANTITATIVE ANALYSIS; REVIEW; RISK FACTOR; SYSTEMATIC REVIEW; TOTAL HIP PROSTHESIS; ADVERSE EFFECTS; DELIRIUM; HIP FRACTURES; HIP REPLACEMENT; META ANALYSIS; POSTOPERATIVE COMPLICATIONS; PROCEDURES; RISK ASSESSMENT;

AGED; ARTHROPLASTY, REPLACEMENT, HIP; DELIRIUM; HIP FRACTURES; HUMANS; INCIDENCE; POSTOPERATIVE COMPLICATIONS; RISK ADJUSTMENT; RISK FACTORS;

EID: 84957941719     PISSN: 15940667     EISSN: 17208319     Source Type: Journal    
DOI: 10.1007/s40520-016-0541-6     Document Type: Review

References (52)

1. Nie H, Zhao B, Zhang YQ et al (2012) Pain and cognitive dysfunction are the risk factors of delirium in elderly hip fracture Chinese patients. Arch Gerontol Geriatr 54:e172–e174. doi:10.1016/j.archger.2011.09.012
2. Wang NY, Hirao A, Sieber F (2015) Association between intraoperative blood pressure and postoperative delirium in elderly hip fracture patients. PLoS One 10:e0123892. doi:10.1371/journal.pone.0123892
3. Lee KH, Ha YC, Lee YK et al (2011) Frequency, risk factors, and prognosis of prolonged delirium in elderly patients after hip fracture surgery. Clin Orthop Relat Res 469:2612–2620. doi:10.1007/s11999-011-1806-1
4. Marcantonio ER, Flacker JM, Michaels M et al (2000) Delirium is independently associated with poor functional recovery after hip fracture. J Am Geriatr Soc 48:618–624
5. Santana Santos F, Wahlund LO, Varli F et al (2005) Incidence, clinical features and subtypes of delirium in elderly patients treated for hip fractures. Dement Geriatr Cogn Disord 20:231–237. doi:10.1159/000087311
6. Chen XW, Shi JW, Yang PS et al (2014) Preoperative plasma leptin levels predict delirium in elderly patients after hip fracture surgery. Peptides 57:31–35. doi:10.1016/j.peptides.2014.04.016
7. Dolan MM, Hawkes WG, Zimmerman SI et al (2000) Delirium on hospital admission in aged hip fracture patients: prediction of mortality and 2-year functional outcomes. J Gerontol Ser A Biol Sci Med Sci 55:M527–M534
8. Goldenberg G, Kiselev P, Bharathan T et al (2006) Predicting post-operative delirium in elderly patients undergoing surgery for hip fracture. Psychogeriatrics 6:43–48. doi:10.1111/j.1479-8301.2006.00146.x
9. Lee HB, Mears SC, Rosenberg PB et al (2011) Predisposing factors for postoperative delirium after hip fracture repair in individuals with and without dementia. J Am Geriatr Soc 59:2306–2313. doi:10.1111/j.1532-5415.2011.03725.x
10. Meziere A, Paillaud E, Belmin J et al (2013) Delirium in older people after proximal femoral fracture repair: role of a preoperative screening cognitive test. Ann Fr Anesth Reanim 32:e91–e96. doi:10.1016/j.annfar.2013.06.006
11. Muangpaisan W, Wongprikron A, Srinonprasert V et al (2015) Incidence and risk factors of acute delirium in older patients with hip fracture in Siriraj Hospital. J Med Assoc Thail 98:423–430
12. Shen Y, Shen H, Zhang W et al (2013) Risk factors for delirium of elderly patients undergoing hip fracture operation. Natl Med J China 93:3276–3279
13. Wang X, Miao W, Huang G (2008) CHnical investigation of postoperative delirium in elderly hip-surgery patients. Chin J Geriatr 27:99–102
14. Wu D, Hao H, Zhu J et al (2015) Risk factors analysis for postoperative delirium of elderly hip fracture patients. Chin J Geriatr Orthop Rehabil 1:34–38
15. Moerman S, Tuinebreijer WE, de Boo M et al (2012) Validation of the risk model for delirium in hip fracture patients. Gen Hosp Psychiatry 34:153–159. doi:10.1016/j.genhosppsych.2011.11.011
16. Gruber-Baldini AL, Zimmerman S, Morrison RS, Grattan LM et al (2003) Cognitive impairment in hip fracture patients: timing of detection and longitudinal follow-up. J Am Geriatr Soc 51:1227–1236
17. Lundstrom M, Edlund A, Bucht G et al (2003) Dementia after delirium in patients with femoral neck fractures. J Am Geriatr Soc 51:1002–1006
18. DSMIV-RD (2000) Statistical manual of mental disorders, text revision (DSM IV-R). American Psychiatric Association, Washington
19. Inouye SK, van Dyck CH, Alessi CA et al (1990) Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med 113:941–948
20. Stang A (2010) Critical evaluation of the Newcastle–Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25:603–605. doi:10.1007/s10654-010-9491-z
21. Lau J, Ioannidis JP, Schmid CH (1997) Quantitative synthesis in systematic reviews. Ann Intern Med 127:820–826
22. Wei J, Yang TB, Luo W et al (2013) Complications following dorsal versus volar plate fixation of distal radius fracture: a meta-analysis. J Int Med Res 41:265–275. doi:10.1177/0300060513476438
23. Kalisvaart KJ, Vreeswijk R, de Jonghe JF et al (2006) Risk factors and prediction of postoperative delirium in elderly hip-surgery patients: implementation and validation of a medical risk factor model. J Am Geriatr Soc 54:817–822. doi:10.1111/j.1532-5415.2006.00704.x
24. Westhoff D, Witlox J, Koenderman L et al (2013) Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients. J Neuroinflamm 10:122. doi:10.1186/1742-2094-10-122
25. Galanakis P, Bickel H, Gradinger R et al (2001) Acute confusional state in the elderly following hip surgery: incidence, risk factors and complications. Int J Geriatr Psychiatry 16:349–355
26. Juliebo V, Bjoro K, Krogseth M et al (2009) Risk factors for preoperative and postoperative delirium in elderly patients with hip fracture. J Am Geriatr Soc 57:1354–1361. doi:10.1111/j.1532-5415.2009.02377.x
27. Schuurmans MJ, Duursma SA, Shortridge-Baggett LM et al (2003) Elderly patients with a hip fracture: the risk for delirium. Appl Nurs Res (ANR) 16:75–84
28. Duppils GS, Wikblad K (2000) Acute confusional states in patients undergoing hip surgery. a prospective observation study. Gerontology 46:36–43. doi10.1159/000022131
29. Morrison RS, Magaziner J, Gilbert M et al (2003) Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol Ser Biol Sci Med Sci 58:76–81
30. Torbergsen AC, Watne LO, Frihagen F et al (2015) Vitamin deficiency as a risk factor for delirium. Eur Geriatr Med 6:314–318. doi:10.1016/j.eurger.2014.09.002
31. Hu W, Zhou M, Tan Z et al (2014) Analysis on the risk factors of postoperative delirium in aged hip fracture patients. J Trauma Surg 16:324–327
32. Lipowski ZJ (1983) Transient cognitive disorders (delirium, acute confusional states) in the elderly. Am J Psychiatry 140:1426–1436. doi:10.1176/ajp.140.11.1426
33. Cole MG, Ciampi A, Belzile E et al (2009) Persistent delirium in older hospital patients: a systematic review of frequency and prognosis. Age Ageing 38:19–26. doi:10.1093/ageing/afn253
34. Cole MG, McCusker J, Dendukuri N et al (2002) Symptoms of delirium among elderly medical inpatients with or without dementia. J Neuropsychiatry Clin Neurosci 14:167–175. doi:10.1176/jncn.14.2.167
35. Blass JP, Gibson GE (1999) Cerebrometabolic aspects of delirium in relationship to dementia. Dement Geriatr Cogn Disord 10:335–338. doi:10.1159/000017165
36. Folstein MF, Folstein SE, McHugh PR (1975) “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12:189–198
37. Hanson MR, Galvez-Jimenez N (2004) Management of dementia and acute confusional states in the perioperative period. Neurol Clin 22:vii–viii, 413–422. doi:10.1016/j.ncl.2004.01.001
38. Sato N, Sanuki M, Matsumoto C et al (2000) Perioperative temporal profile of cognitive function in elderly patients undergoing hip surgery. J Geriatr Psychiatry Neurol 13:206–209
39. van der Mast RC (1998) Pathophysiology of delirium. J Geriatr Psychiatry Neurol 11:138–145 (discussion 157-138)
40. Owens WD, Felts JA, Spitznagel EL Jr (1978) ASA physical status classifications: a study of consistency of ratings. Anesthesiology 49:239–243
41. Charlson ME, Pompei P, Ales KL et al (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383
42. Mullen JO, Mullen NL (1992) Hip fracture mortality. A prospective, multifactorial study to predict and minimize death risk. Clin Orthop Relat Res 280:214–222
43. Edlund A, Lundstrom M, Brannstrom B et al (2001) Delirium before and after operation for femoral neck fracture. J Am Geriatr Soc 49:1335–1340
44. Dasgupta M, Dumbrell AC (2006) Preoperative risk assessment for delirium after noncardiac surgery: a systematic review. J Am Geriatr Soc 54:1578–1589. doi:10.1111/j.1532-5415.2006.00893.x
45. Tomkins DM, Sellers EM (2001) Addiction and the brain: the role of neurotransmitters in the cause and treatment of drug dependence. Can Med Assoc J (CMAJ) 164:817–821
46. Cowen MS, Lawrence AJ (1999) The role of opioid–dopamine interactions in the induction and maintenance of ethanol consumption. Prog Neuropsychopharmacol Biol Psychiatry 23:1171–1212
47. Gaudreau JD, Gagnon P, Harel F et al (2005) Psychoactive medications and risk of delirium in hospitalized cancer patients. J Clin Oncol 23:6712–6718. doi:10.1200/jco.2005.05.140
48. Dubois MJ, Bergeron N, Dumont M et al (2001) Delirium in an intensive care unit: a study of risk factors. Intensive Care Med 27:1297–1304
49. Vaurio LE, Sands LP, Wang Y et al (2006) Postoperative delirium: the importance of pain and pain management. Anesth Analg 102:1267–1273. doi:10.1213/01.ane.0000199156.59226.af
50. Jankowski CJ, Trenerry MR, Cook DJ et al (2011) Cognitive and functional predictors and sequelae of postoperative delirium in elderly patients undergoing elective joint arthroplasty. Anesth Analg 112:1186–1193. doi:10.1213/ANE.0b013e318211501b
51. Rao SS (2005) Prevention of falls in older patients. Am Fam Phys 72:81–88
52. Williams-Russo P, Urquhart BL, Sharrock NE et al (1992) Post-operative delirium: predictors and prognosis in elderly orthopedic patients. J Am Geriatr Soc 40:759–767