Analysis of Outcomes Using Low-Dose and Early Administration of Recombinant Activated Factor VII in Cardiac Surgery

Annals of Thoracic Surgery

Volumn 102, Issue 1, 2016, Pages 35-40

  Brase, Jason ^a   Finger, Brooke ^a   He, Jianghua ^a   Wirtz, Katy ^a   Stun, Lucy ^a   McMillen, Randy ^a   Flynn, Brigid ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 7A; RECOMBINANT FVIIA; RECOMBINANT PROTEIN;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DEEP VEIN THROMBOSIS; FEMALE; GRAFT OCCLUSION; HEART SURGERY; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; LOW DRUG DOSE; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MORBIDITY; OPERATIVE BLOOD LOSS; PNEUMONIA; POSTOPERATIVE COMPLICATION; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; REOPERATION; SOCIETY OF THORACIC SURGEONS SCORE; SURGICAL INFECTION; SURGICAL MORTALITY; TRANSIENT ISCHEMIC ATTACK; TREATMENT OUTCOME; ADVERSE EFFECTS; BLOOD; DOSE RESPONSE; FOLLOW UP; KANSAS; METABOLISM; MIDDLE AGED; RETROSPECTIVE STUDY; SURVIVAL RATE; TIME FACTOR; TRENDS; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; CARDIAC SURGICAL PROCEDURES; DOSE-RESPONSE RELATIONSHIP, DRUG; FACTOR VII; FACTOR VIIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTENSIVE CARE UNITS; KANSAS; MALE; MIDDLE AGED; MORBIDITY; POSTOPERATIVE HEMORRHAGE; RECOMBINANT PROTEINS; RETROSPECTIVE STUDIES; SURVIVAL RATE; TIME FACTORS; YOUNG ADULT;

EID: 84957900330     PISSN: 00034975     EISSN: 15526259     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2016.01.004     Document Type: Article

References (28)

1. U. Hedner, and W. Kisiel Use of human factor VIIa in the treatment of two hemophilia A patients with high-titer inhibitors J Clin Invest 71 1983 1836 1841
2. U. Hedner, S. Bjoern, S.S. Bernvil, L. Tengborn, and L. Stigendahl Clinical experience with human plasma-derived factor VIIa in patients with hemophilia A and high titer inhibitors Haemostasis 19 1989 335 343
3. A. Mayo, M. Misgav, Y. Kluger, and et al. Recombinant activated factor VII (NovoSeven): addition to replacement therapy in acute, uncontrolled and life-threatening bleeding Vox Sang 87 2004 34 40
4. N.D. Andersen, S.D. Bhattacharya, J.B. Williams, and et al. Intraoperative use of low-dose recombinant activated factor VII during thoracic aortic operations Ann Thorac Surg 93 2012 1921 1928
5. R. Gill, M. Herbertson, A. Vuylsteke, and et al. Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery Circulation 120 2009 21 27
6. A. Alfirevic, A. Duncan, J. You, C. Lober, and E. Soltesz Recombinant factor VII is associated with worse survival in complex cardiac surgical patients Ann Thorac Surg 98 2014 618 624
7. M. Ponschab, G. Landoni, G. Biondi-Zoccai, and et al. Recombinant activated factor VII increases stroke in cardiac surgery: a meta-analysis J Cardiothorac Vasc Anesth 25 2011 804 810
8. A. Zangrillo, A. Mizzi, G. Biondi-Zoccai, and et al. Recombinant activated factor VII in cardiac surgery: a meta-analysis J Cardiothorac Vasc Anesth 23 2009 34 40
9. G. Young, F.E. Shafer, P. Rojas, and S. Seremetis Single 270 microg kg(-1)-dose rFVIIa vs. standard 90 microg kg(-1)-dose rFVIIa and APCC for home treatment of joint bleeds in haemophilia patients with inhibitors: a randomized comparison Haemophilia 14 2008 287 294
10. K. Kavakli, M. Makris, B. Zulfikar, and et al. Home treatment of haemarthroses using a single dose regimen of recombinant activated factor VII in patients with haemophilia and inhibitors: a multi-centre, randomised, double-blind, cross-over trial Thromb Haemost 95 2006 600 605
11. T. Syburra, M. Lachat, M. Genoni, and M.J. Wilhelm Fatal outcome of recombinant factor VIIa in heart transplantation with extracorporeal membrane oxygenation Ann Thorac Surg 89 2010 1643 1645
12. K. Karkouti, W.S. Beattie, D.N. Wijeysundera, and et al. Recombinant factor VIIa for intractable blood loss after cardiac surgery: a propensity score-matched case-control analysis Transfusion 45 2005 26 34
13. E.M. van de Garde, L.J. Bras, R.H. Heijmen, and et al. Low-dose recombinant factor VIIa in the management of uncontrolled postoperative hemorrhage in cardiac surgery patients J Cardiothorac Vasc Anesth 20 2006 573 575
14. A.L. Shroyer, M.E. Plomondon, F.L. Grover, and F.H. Edwards The 1996 coronary artery bypass risk model: The Society of Thoracic Surgeons Adult Cardiac National Database Ann Thorac Surg 67 1999 1205 1208
15. C. Dyke, S. Aronson, W. Dietrich, and et al. Universal definition of perioperative bleeding in adult cardiac surgery J Cardiothorac Vasc Anesth 147 2014 1458 1463
16. G. Montalescot, R. Gallo, H.D. White, and et al. Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention 1-year results from the STEEPLE (SafeTy and efficacy of enoxaparin in percutaneous coronary intervention patients, an international randomized evaluation) trial JACC Cardiovasc Interv 2 2009 1083 1091
17. GRACE Investigators Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: a multinational registry of patients hospitalized with acute coronary syndromes Am Heart J 141 2001 190 199
18. L.L. Saint, R.J. Damiano Jr., P.S. Cuculich, and et al. Incremental risk of the Cox-maze IV procedure for patients with atrial fibrillation undergoing mitral valve surgery J Thorac Cardiovasc Surg 146 2013 1072 1077
19. R. Bellomo, C. Ronco, J.A. Kellum, R.L. Mehta, and P. Palevsky Acute Dialysis Quality Initiative Workgroup. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group Crit Care 8 2004 R204 R212
20. R.L. Mehta, J.A. Kellum, S.V. Shah, and et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury Crit Care 11 2007 R31
21. S. Gelsomino, R. Lorusso, S. Romagnoli, and et al. Treatment of refractory bleeding after cardiac operations with low-dose recombinant activated factor VII (NovoSeven): a propensity score analysis Eur J Cardiothorac Surg 33 2008 64 71
22. K. Karkouti, W.S. Beattie, R. Arellano, and et al. Comprehensive Canadian review of the off-label use of recombinant activated factor VII in cardiac surgery Circulation 118 2008 331 338
23. D.M. Stein, R.P. Dutton, J. O'Connor, M. Alexander, and T.M. Scalea Determinants of futility of administration of recombinant factor VIIa in trauma J Trauma 59 2005 609 615
24. T.A. Drake, J.H. Morrissey, and T.S. Edgington Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis Am J Pathol 134 1989 1087 1097
25. G. Pang, and A. Donaldson Probable right atrial thrombus immediately after recombinant activated factor VII administration Br J Anaesth 99 2007 221 225
26. A.D. Lichtman, V. Carullo, M. Minhaj, and K. Karkouti Case 6 - 2007: massive intraoperative thrombosis and death after recombinant activated factor VII administration J Thorac Cardiovasc Surg 21 2007 897 902
27. A.J. Chapman, A.L. Blount, A.T. Davis, and R.L. Hooker Recombinant factor VIIa (NovoSeven RT) use in high risk cardiac surgery Eur J Cardiothorac Surg 40 2011 1314 1318
28. R. Wynne, M. Botti, D. Copley, and M. Bailey The normative distribution of chest tube drainage volume after coronary artery bypass grafting Heart Lung 36 2007 35 42