메뉴 건너뛰기




Volumn 28, Issue 8, 2016, Pages 532-539

Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome

Author keywords

5 fluorouracil; chemoradiotherapy; locally advanced rectal cancer; neoadjuvant chemotherapy; oxaliplatin

Indexed keywords

ALBUMIN; CAPECITABINE; CREATININE; ELECTROLYTE; FLUOROURACIL; FOLINIC ACID; HEMOGLOBIN; OXALIPLATIN; ANTINEOPLASTIC AGENT; PLATINUM COMPLEX;

EID: 84957899722     PISSN: 09366555     EISSN: 14332981     Source Type: Journal    
DOI: 10.1016/j.clon.2016.01.014     Document Type: Article
Times cited : (30)

References (28)
  • 1
    • 80155150299 scopus 로고    scopus 로고
    • The current landscape of locally advanced rectal cancer
    • [1] Aklilu, M., Eng, C., The current landscape of locally advanced rectal cancer. Nat Rev Clin Oncol 8 (2011), 649–659.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 649-659
    • Aklilu, M.1    Eng, C.2
  • 2
    • 84893020737 scopus 로고    scopus 로고
    • Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study
    • [2] Bosset, J.F., Calais, G., Mineur, L., et al. Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study. Lancet Oncol 15 (2014), 184–190.
    • (2014) Lancet Oncol , vol.15 , pp. 184-190
    • Bosset, J.F.1    Calais, G.2    Mineur, L.3
  • 3
    • 84871725058 scopus 로고    scopus 로고
    • Clinical outcome of the ACCORD 12/0405 PRODIGE 2 randomized trial in rectal cancer
    • [3] Gerard, J.P., Azria, D., Gourgou-Bourgade, S., et al. Clinical outcome of the ACCORD 12/0405 PRODIGE 2 randomized trial in rectal cancer. J Clin Oncol 30 (2012), 4558–4565.
    • (2012) J Clin Oncol , vol.30 , pp. 4558-4565
    • Gerard, J.P.1    Azria, D.2    Gourgou-Bourgade, S.3
  • 4
    • 84907017989 scopus 로고    scopus 로고
    • Enhancing the efficacy of radiation therapy: premises, promises, and practicality
    • [4] Coleman, C.N., Lawrence, T.S., Kirsch, D.G., Enhancing the efficacy of radiation therapy: premises, promises, and practicality. J Clin Oncol 32 (2014), 2832–2835.
    • (2014) J Clin Oncol , vol.32 , pp. 2832-2835
    • Coleman, C.N.1    Lawrence, T.S.2    Kirsch, D.G.3
  • 5
    • 84874130092 scopus 로고    scopus 로고
    • Pre-operative chemoradiation for non-metastatic locally advanced rectal cancer
    • [5] McCarthy, K., Pearson, K., Fulton, R., et al. Pre-operative chemoradiation for non-metastatic locally advanced rectal cancer. Cochrane Database Syst Rev, 12, 2012, CD008368.
    • (2012) Cochrane Database Syst Rev , vol.12 , pp. CD008368
    • McCarthy, K.1    Pearson, K.2    Fulton, R.3
  • 6
    • 84904760138 scopus 로고    scopus 로고
    • Milestones in the use of combined-modality radiation therapy and chemotherapy
    • [6] Lawrence, T.S., Haffty, B.G., Harris, J.R., Milestones in the use of combined-modality radiation therapy and chemotherapy. J Clin Oncol 32 (2014), 1173–1179.
    • (2014) J Clin Oncol , vol.32 , pp. 1173-1179
    • Lawrence, T.S.1    Haffty, B.G.2    Harris, J.R.3
  • 7
    • 40749149728 scopus 로고    scopus 로고
    • Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial
    • [7] Nordlinger, B., Sorbye, H., Glimelius, B., et al. Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet 371 (2008), 1007–1016.
    • (2008) Lancet , vol.371 , pp. 1007-1016
    • Nordlinger, B.1    Sorbye, H.2    Glimelius, B.3
  • 8
    • 84886719568 scopus 로고    scopus 로고
    • Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial
    • [8] Nordlinger, B., Sorbye, H., Glimelius, B., et al. Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial. Lancet Oncol 14 (2013), 1208–1215.
    • (2013) Lancet Oncol , vol.14 , pp. 1208-1215
    • Nordlinger, B.1    Sorbye, H.2    Glimelius, B.3
  • 9
    • 77950495945 scopus 로고    scopus 로고
    • Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2
    • [9] Gerard, J.P., Azria, D., Gourgou-Bourgade, S., et al. Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2. J Clin Oncol 28 (2010), 1638–1644.
    • (2010) J Clin Oncol , vol.28 , pp. 1638-1644
    • Gerard, J.P.1    Azria, D.2    Gourgou-Bourgade, S.3
  • 10
    • 79960242791 scopus 로고    scopus 로고
    • Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial
    • [10] Aschele, C., Cionini, L., Lonardi, S., et al. Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial. J Clin Oncol 29 (2011), 2773–2780.
    • (2011) J Clin Oncol , vol.29 , pp. 2773-2780
    • Aschele, C.1    Cionini, L.2    Lonardi, S.3
  • 11
    • 84905457749 scopus 로고    scopus 로고
    • Capecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04
    • [11] O'Connell, M.J., Colangelo, L.H., Beart, R.W., et al. Capecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04. J Clin Oncol 32 (2014), 1927–1934.
    • (2014) J Clin Oncol , vol.32 , pp. 1927-1934
    • O'Connell, M.J.1    Colangelo, L.H.2    Beart, R.W.3
  • 12
    • 84863106037 scopus 로고    scopus 로고
    • Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial
    • [12] Rodel, C., Liersch, T., Becker, H., et al. Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial. Lancet Oncol 13 (2012), 679–687.
    • (2012) Lancet Oncol , vol.13 , pp. 679-687
    • Rodel, C.1    Liersch, T.2    Becker, H.3
  • 13
    • 84938211714 scopus 로고    scopus 로고
    • Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial
    • [13] Rodel, C., Graeven, U., Fietkau, R., et al. Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial. Lancet Oncol 16 (2015), 979–989.
    • (2015) Lancet Oncol , vol.16 , pp. 979-989
    • Rodel, C.1    Graeven, U.2    Fietkau, R.3
  • 14
    • 0037406971 scopus 로고    scopus 로고
    • Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison
    • [14] Brown, G., Richards, C.J., Bourne, M.W., et al. Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison. Radiology 227 (2003), 371–377.
    • (2003) Radiology , vol.227 , pp. 371-377
    • Brown, G.1    Richards, C.J.2    Bourne, M.W.3
  • 15
    • 3242717539 scopus 로고    scopus 로고
    • Multicenter phase II study of Nordic fluorouracil and folinic acid bolus schedule combined with oxaliplatin as first-line treatment of metastatic colorectal cancer
    • [15] Sorbye, H., Glimelius, B., Berglund, A., et al. Multicenter phase II study of Nordic fluorouracil and folinic acid bolus schedule combined with oxaliplatin as first-line treatment of metastatic colorectal cancer. J Clin Oncol 22 (2004), 31–38.
    • (2004) J Clin Oncol , vol.22 , pp. 31-38
    • Sorbye, H.1    Glimelius, B.2    Berglund, A.3
  • 16
    • 49249090949 scopus 로고    scopus 로고
    • Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer
    • [16] Braendengen, M., Tveit, K.M., Berglund, A., et al. Randomized phase III study comparing preoperative radiotherapy with chemoradiotherapy in nonresectable rectal cancer. J Clin Oncol 26 (2008), 3687–3694.
    • (2008) J Clin Oncol , vol.26 , pp. 3687-3694
    • Braendengen, M.1    Tveit, K.M.2    Berglund, A.3
  • 17
    • 33750071992 scopus 로고    scopus 로고
    • Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study
    • [17] MERCURY Study Group, Diagnostic accuracy of preoperative magnetic resonance imaging in predicting curative resection of rectal cancer: prospective observational study. Br Med J, 333, 2006, 779.
    • (2006) Br Med J , vol.333 , pp. 779
    • MERCURY Study Group1
  • 18
    • 68149178697 scopus 로고    scopus 로고
    • A uniform residual tumor (R) classification: integration of the R classification and the circumferential margin status
    • [18] Wittekind, C., Compton, C., Quirke, P., et al. A uniform residual tumor (R) classification: integration of the R classification and the circumferential margin status. Cancer 115 (2009), 3483–3488.
    • (2009) Cancer , vol.115 , pp. 3483-3488
    • Wittekind, C.1    Compton, C.2    Quirke, P.3
  • 19
    • 0037083343 scopus 로고    scopus 로고
    • Importance of tumor regression assessment in predicting the outcome in patients with locally advanced rectal carcinoma who are treated with preoperative radiotherapy
    • [19] Bouzourene, H., Bosman, F.T., Seelentag, W., et al. Importance of tumor regression assessment in predicting the outcome in patients with locally advanced rectal carcinoma who are treated with preoperative radiotherapy. Cancer 94 (2002), 1121–1130.
    • (2002) Cancer , vol.94 , pp. 1121-1130
    • Bouzourene, H.1    Bosman, F.T.2    Seelentag, W.3
  • 20
    • 33745622869 scopus 로고    scopus 로고
    • Improved incidence of pT0 downstaged surgical specimens in locally advanced rectal cancer (LARC) treated with induction oxaliplatin plus 5-fluorouracil and preoperative chemoradiation
    • [20] Calvo, F.A., Serrano, F.J., Diaz-Gonzalez, J.A., et al. Improved incidence of pT0 downstaged surgical specimens in locally advanced rectal cancer (LARC) treated with induction oxaliplatin plus 5-fluorouracil and preoperative chemoradiation. Ann Oncol 17 (2006), 1103–1110.
    • (2006) Ann Oncol , vol.17 , pp. 1103-1110
    • Calvo, F.A.1    Serrano, F.J.2    Diaz-Gonzalez, J.A.3
  • 21
    • 33644846344 scopus 로고    scopus 로고
    • Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer
    • [21] Chau, I., Brown, G., Cunningham, D., et al. Neoadjuvant capecitabine and oxaliplatin followed by synchronous chemoradiation and total mesorectal excision in magnetic resonance imaging-defined poor-risk rectal cancer. J Clin Oncol 24 (2006), 668–674.
    • (2006) J Clin Oncol , vol.24 , pp. 668-674
    • Chau, I.1    Brown, G.2    Cunningham, D.3
  • 22
    • 41649097959 scopus 로고    scopus 로고
    • Phase II study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer
    • [22] Koeberle, D., Burkhard, R., von Moos, R., et al. Phase II study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer. Br J Cancer 98 (2008), 1204–1209.
    • (2008) Br J Cancer , vol.98 , pp. 1204-1209
    • Koeberle, D.1    Burkhard, R.2    von Moos, R.3
  • 23
    • 73249132436 scopus 로고    scopus 로고
    • The effect on the small bowel of 5-FU and oxaliplatin in combination with radiation using a microcolony survival assay
    • [23] Gunnlaugsson, A., Nilsson, P., Kjellen, E., et al. The effect on the small bowel of 5-FU and oxaliplatin in combination with radiation using a microcolony survival assay. Radiat Oncol, 4, 2009, 61.
    • (2009) Radiat Oncol , vol.4 , pp. 61
    • Gunnlaugsson, A.1    Nilsson, P.2    Kjellen, E.3
  • 24
    • 77349110719 scopus 로고    scopus 로고
    • Neoadjuvant capecitabine and oxaliplatin before chemoradiotherapy and total mesorectal excision in MRI-defined poor-risk rectal cancer: a phase 2 trial
    • [24] Chua, Y.J., Barbachano, Y., Cunningham, D., et al. Neoadjuvant capecitabine and oxaliplatin before chemoradiotherapy and total mesorectal excision in MRI-defined poor-risk rectal cancer: a phase 2 trial. Lancet Oncol 11 (2010), 241–248.
    • (2010) Lancet Oncol , vol.11 , pp. 241-248
    • Chua, Y.J.1    Barbachano, Y.2    Cunningham, D.3
  • 25
    • 84863743780 scopus 로고    scopus 로고
    • Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C)
    • [25] Dewdney, A., Cunningham, D., Tabernero, J., et al. Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C). J Clin Oncol 30 (2012), 1620–1627.
    • (2012) J Clin Oncol , vol.30 , pp. 1620-1627
    • Dewdney, A.1    Cunningham, D.2    Tabernero, J.3
  • 26
    • 84867137033 scopus 로고    scopus 로고
    • Induction chemotherapy with capecitabine and oxaliplatin followed by chemoradiotherapy before total mesorectal excision in patients with locally advanced rectal cancer
    • [26] Schou, J.V., Larsen, F.O., Rasch, L., et al. Induction chemotherapy with capecitabine and oxaliplatin followed by chemoradiotherapy before total mesorectal excision in patients with locally advanced rectal cancer. Ann Oncol 23 (2012), 2627–2633.
    • (2012) Ann Oncol , vol.23 , pp. 2627-2633
    • Schou, J.V.1    Larsen, F.O.2    Rasch, L.3
  • 27
    • 84860895570 scopus 로고    scopus 로고
    • Diagnostic accuracy of MRI for assessment of T category, lymph node metastases, and circumferential resection margin involvement in patients with rectal cancer: a systematic review and meta-analysis
    • [27] Al-Sukhni, E., Milot, L., Fruitman, M., et al. Diagnostic accuracy of MRI for assessment of T category, lymph node metastases, and circumferential resection margin involvement in patients with rectal cancer: a systematic review and meta-analysis. Ann Surg Oncol 19 (2012), 2212–2223.
    • (2012) Ann Surg Oncol , vol.19 , pp. 2212-2223
    • Al-Sukhni, E.1    Milot, L.2    Fruitman, M.3
  • 28
    • 40249094484 scopus 로고    scopus 로고
    • Inhibitory effects of oxaliplatin in experimental radiation treatment of colorectal carcinoma: does oxaliplatin improve 5-fluorouracil-dependent radiosensitivity?
    • [28] Folkvord, S., Flatmark, K., Seierstad, T., et al. Inhibitory effects of oxaliplatin in experimental radiation treatment of colorectal carcinoma: does oxaliplatin improve 5-fluorouracil-dependent radiosensitivity?. Radiother Oncol 86 (2008), 428–434.
    • (2008) Radiother Oncol , vol.86 , pp. 428-434
    • Folkvord, S.1    Flatmark, K.2    Seierstad, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.