Opposite Sex Contact and Isolation: A Novel Depression/Anxiety Model

Neuroscience Bulletin

Volumn 32, Issue 1, 2016, Pages 92-98

  Yang, Liu ^b   Shi, Li Jun ^a   Tang, Bei ^a   Han, Qiu Qin ^a   Yu, Jin ^a   Wu, Gen Cheng ^a   Zhang, Yu Qiu ^a  

^a FUDAN UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Anxiety; Depression; Lovelorn; Opposite sex contact; Social isolation; Social stress

Indexed keywords

BINDING PROTEIN; CORTICOSTERONE; CYCLIC AMP; CREB1 PROTEIN, MOUSE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BEHAVIOR DISORDER; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; DISEASE EXACERBATION; FEMALE; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; OPPOSITE SEX CONTACT AND ISOLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SOCIAL AVOIDANCE BEHAVIOR; SOCIAL ISOLATION; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; BLOOD; C57BL MOUSE; DISEASE MODEL; FLUORESCENT ANTIBODY TECHNIQUE; MAZE TEST; METABOLISM; PSYCHOLOGY;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; CORTICOSTERONE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DEPRESSION; DISEASE MODELS, ANIMAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; NUCLEUS ACCUMBENS; SOCIAL ISOLATION;

EID: 84957601862     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-015-0002-9     Document Type: Article

References (20)

1. Han Q, Yang L, Liu Y, Lv N, Yu J, Wu G, et al. Resiliency to social defeat stress relates to the inter-strain social interaction and is influenced by season variation. Neurosci Lett 2014, 561: 13–17.
2. Filova B, Malinova M, Babickova J, Tothova L, Ostatnikova D, Celec P, et al. Effects of testosterone and estradiol on anxiety and depressive-like behavior via a non-genomic pathway. Neurosci Bull 2015, 31: 288–296.
3. Song H, Zou Z, Kou J, Liu Y, Yang L, Zilverstand A, et al. Love-related changes in the brain: a resting-state functional magnetic resonance imaging study. Front Hum Neurosci 2015, 9: 71.
4. Bledsoe AC, Oliver KM, Scholl JL, Forster GL. Anxiety states induced by post-weaning social isolation are mediated by CRF receptors in the dorsal raphe nucleus. Brain Res Bull 2011, 85: 117–122.
5. Chappell AM, Carter E, McCool BA, Weiner JL. Adolescent rearing conditions influence the relationship between initial anxiety-like behavior and ethanol drinking in male Long Evans rats. Alcohol Clin Exp Res 2013, 37 Suppl 1: E394–E403.
6. Hodges TE, McCormick CM. Adolescent and adult male rats habituate to repeated isolation, but only adolescents sensitize to partner unfamiliarity. Horm Behav 2015, 69: 16–30.
7. Barrot M, Wallace DL, Bolanos CA, Graham DL, Perrotti LI, Neve RL, et al. Regulation of anxiety and initiation of sexual behavior by CREB in the nucleus accumbens. Proc Natl Acad Sci USA 2005, 102: 8357–8362.
8. Barrot M, Olivier JD, Perrotti LI, DiLeone RJ, Berton O, Eisch AJ, et al. CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proc Natl Acad Sci USA 2002, 99: 11435–11440.
9. Tenayuca JM, Nazarian A. Hydrocodone and morphine possess similar rewarding effects and reduce ERK and CREB phosphorylation in the nucleus accumbens. Synapse 2012, 66: 918–922.
10. Hou H, Wang C, Jia S, Hu S, Tian M. Brain dopaminergic system changes in drug addiction: a review of positron emission tomography findings. Neurosci Bull 2014, 30: 765–776.
11. Gill KM, Grace AA. Differential effects of acute and repeated stress on hippocampus and amygdala inputs to the nucleus accumbens shell. Int J Neuropsychopharmacol 2013, 16: 2013–2025.
12. Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, et al. Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior. Proc Natl Acad Sci USA 2012, 109: 11360–11365.
13. Vazquez-Roque RA, Ramos B, Tecuatl C, Juarez I, Adame A, de la Cruz F, et al. Chronic administration of the neurotrophic agent cerebrolysin ameliorates the behavioral and morphological changes induced by neonatal ventral hippocampus lesion in a rat model of schizophrenia. J Neurosci Res 2012, 90: 288–306.
14. Belujon P, Grace AA. Critical role of the prefrontal cortex in the regulation of hippocampus-accumbens information flow. J Neurosci 2008, 28: 9797–9805.
15. Lee BR, Ma YY, Huang YH, Wang X, Otaka M, Ishikawa M, et al. Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving. Nat Neurosci 2013, 16: 1644–1651.
16. Terranova ML, Cirulli F, Laviola G. Behavioral and hormonal effects of partner familiarity in periadolescent rat pairs upon novelty exposure. Psychoneuroendocrinology 1999, 24: 639–656.
17. Faraday MM, Blakeman KH, Grunberg NE. Strain and sex alter effects of stress and nicotine on feeding, body weight, and HPA axis hormones. Pharmacol Biochem Behav 2005, 80: 577–589.
18. Lombana K, Middleton N, Coddington E. Suppression of sex behavior by kappa opiates and stress steroids occurs via independent neuroendocrine pathways. Gen Comp Endocrinol 2015, 210: 81–86.
19. Boyd SK, Moore FL. Evidence for GABA involvement in stress-induced inhibition of male amphibian sexual behavior. Horm Behav 1990, 24: 128–138.
20. Moore FL, Miller LJ. Stress-induced inhibition of sexual behavior: corticosterone inhibits courtship behaviors of a male amphibian (Taricha granulosa). Horm Behav 1984, 18: 400–410.