Statistical considerations for a trial of Ebola virus disease therapeutics

Clinical Trials

Volumn 13, Issue 1, 2016, Pages 39-48

  Proschan, Michael A ^a   Dodd, Lori E ^a   Price, Dionne ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Barnard's test; Bayesian methods; beta binomial distribution; conditional power; emerging infectious diseases; Fisher's exact test; group sequential monitoring; non informative prior

Indexed keywords

ARTICLE; BARNARD TEST; BAYES THEOREM; CALCULATION; CLINICAL TRIAL (TOPIC); DRUG EFFICACY; DRUG MONITORING; EBOLA HEMORRHAGIC FEVER; FISHER EXACT TEST; HUMAN; HYPOTHESIS; INTERMETHOD COMPARISON; PRIORITY JOURNAL; PROBABILITY; RISK BENEFIT ANALYSIS; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL CONCEPTS; STUDY DESIGN; HEMORRHAGIC FEVER, EBOLA; METHODOLOGY; MORTALITY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL (TOPIC); TREATMENT OUTCOME;

ANTIVIRUS AGENT; MONOCLONAL ANTIBODY; ZMAPP;

ANTIBODIES, MONOCLONAL; ANTIVIRAL AGENTS; BAYES THEOREM; DATA INTERPRETATION, STATISTICAL; HEMORRHAGIC FEVER, EBOLA; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN; TREATMENT OUTCOME;

EID: 84957583391     PISSN: 17407745     EISSN: 17407753     Source Type: Journal    
DOI: 10.1177/1740774515620145     Document Type: Article

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