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Volumn 14, Issue 2, 2016, Pages 157-165

Dasabuvir (ABT333) for the treatment of chronic HCV genotype I: A new face of cure, an expert review

Author keywords

3D; ABT 333; ABT 450; Dasabuvir; direct antiviral agents (DAA); HCV; polymerase inhibitor; sustained virological response (SVR)

Indexed keywords

DASABUVIR; DASABUVIR PLUS OMBITASVIR PLUS PARITAPREVIR PLUS RITONAVIR; HEPACIVIRIN INHIBITOR; NONSTRUCTURAL PROTEIN 5B; OMBITASVIR; PARITAPREVIR PLUS RITONAVIR; PEGINTERFERON; PLACEBO; RIBAVIRIN; UNCLASSIFIED DRUG; ABT-333; ANTIVIRUS AGENT; DRUG COMBINATION; INTERFERON; MACROCYCLIC COMPOUND; RITONAVIR; SULFONAMIDE; URACIL;

EID: 84957434752     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/14787210.2016.1120668     Document Type: Article
Times cited : (15)

References (29)
  • 1
    • 79953171086 scopus 로고    scopus 로고
    • Increasing prevalence of HCC and cirrhosis in patients with chronic hepatitis C virus infection
    • Kanwal F, Hoang T, Kramer JR, et al. Increasing prevalence of HCC and cirrhosis in patients with chronic hepatitis C virus infection. Gastroenterology. 2011;140 (4):1182-8
    • (2011) Gastroenterology , vol.140 , Issue.4 , pp. 1182-1188
    • Kanwal, F.1    Hoang, T.2    Kramer, J.R.3
  • 3
    • 84885799512 scopus 로고    scopus 로고
    • HCV-related autoimmune disorders in HCV chronic infection
    • Ferrari SM, Fallahi P, Mancusi C, et al. HCV-related autoimmune disorders in HCV chronic infection. Clin Ter. 2013;164: e305-12
    • (2013) Clin ter , vol.164 , pp. e305-e312
    • Ferrari, S.M.1    Fallahi, P.2    Mancusi, C.3
  • 4
    • 84872221986 scopus 로고    scopus 로고
    • Direct-acting antiviral agents for hepatitis C virus infection
    • Kiser JJ, Flexner C. Direct-acting antiviral agents for hepatitis C virus infection. Annu Rev Pharmacol Toxicol. 2013;53:427-449
    • (2013) Annu Rev Pharmacol Toxicol , vol.53 , pp. 427-449
    • Kiser, J.J.1    Flexner, C.2
  • 5
    • 0034828776 scopus 로고    scopus 로고
    • Myasthenia gravis during low dose IFN alpha therapy for chronic hepatitis C j Interferon
    • Borgia G, Reynauds L, Gentile I, et al. Myasthenia gravis during low dose IFN alpha therapy for chronic hepatitis C. j Interferon. Cytokine Res. 2001;21(7):469-470
    • (2001) Cytokine Res , vol.21 , Issue.7 , pp. 469-470
    • Borgia, G.1    Reynauds, L.2    Gentile, I.3
  • 6
    • 18644362652 scopus 로고    scopus 로고
    • Hemolytic anemia during Pegylated IFN-alpha 2b plus ribavirin treatment for chronic hepatitis C: Ribavirin is not always the culprit
    • Gentile I, Viola C, Reynaud L, et al. Hemolytic anemia during Pegylated IFN-alpha 2b plus ribavirin treatment for chronic hepatitis C: ribavirin is not always the culprit. J Interferon Cytokine Res. 2005;25(5):283-285
    • (2005) J Interferon Cytokine Res , vol.25 , Issue.5 , pp. 283-285
    • Gentile, I.1    Viola, C.2    Reynaud, L.3
  • 7
    • 34548165221 scopus 로고    scopus 로고
    • A case of Pegylated interferon alpha-related diabetic ketoacidosis: Can this complication be avoided?
    • Tosone G, Borgia G, Gentile I, et al A case of Pegylated interferon alpha-related diabetic ketoacidosis: can this complication be avoided?. Acta Diabetol. 2007;44 (3):167-169
    • (2007) Acta Diabetol , vol.44 , Issue.3 , pp. 167-169
    • Tosone, G.1    Borgia, G.2    Gentile, I.3
  • 8
    • 72049091527 scopus 로고    scopus 로고
    • The efficacy and safety of telaprevir-A new protease inhibitor gainst hepatitis C virus
    • Gentile Viola C, Borgia F, et al. The efficacy and safety of telaprevir-A new protease inhibitor gainst hepatitis C virus. Expert Opin Investig Drugs. 2010;19(1):151-159
    • (2010) Expert Opin Investig Drugs , vol.19 , Issue.1 , pp. 151-159
    • Gentile Viola, C.1    Borgia, F.2
  • 9
    • 65449136656 scopus 로고    scopus 로고
    • Diagnosis, management and treatment of hepatitis C: An update
    • Ghany MG, Strader DB, Thomas DL, et al. Diagnosis, management and treatment of hepatitis C: an update. Hepatology. 2009;49(4):1335-1374
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1335-1374
    • Ghany, M.G.1    Strader, D.B.2    Thomas, D.L.3
  • 10
    • 84899651307 scopus 로고    scopus 로고
    • Peg-interferon plus ribavirin with or without boceprevir or telaprevir for HCV Genotype 1: A meta-analysis on the role of response predictors
    • Coppola N, Pisaturo M, Sagnelli C, et al Peg-interferon plus ribavirin with or without boceprevir or telaprevir for HCV Genotype 1: a meta-analysis on the role of response predictors. PLoS ONE. 2014;9:4
    • (2014) PLoS ONE , vol.9 , pp. 4
    • Coppola, N.1    Pisaturo, M.2    Sagnelli, C.3
  • 11
    • 84924408414 scopus 로고    scopus 로고
    • Dasabuvir: A nonnucleoside inhibitor of NS5B for the treatment of Hepatitis C virus infection
    • Gentile I, Buonomo AR, Borgia G. Dasabuvir: a nonnucleoside inhibitor of NS5B for the treatment of Hepatitis C virus infection. Rev Recent Clin Trials. 2014;9:115-123
    • (2014) Rev Recent Clin Trials , vol.9 , pp. 115-123
    • Gentile, I.1    Buonomo, A.R.2    Borgia, G.3
  • 12
    • 84870021542 scopus 로고    scopus 로고
    • Nucleoside/Nucleotide analogue polymerase inhibitors in development
    • Pockros PJ. Nucleoside/Nucleotide analogue polymerase inhibitors in development. Clin Liver Dis. 2013;17:105-110
    • (2013) Clin Liver Dis , vol.17 , pp. 105-110
    • Pockros, P.J.1
  • 13
    • 84890947330 scopus 로고    scopus 로고
    • Novel therapeutic approaches for hepatitis C
    • Au JS, Pockros PJ. Novel therapeutic approaches for hepatitis C. Clin Pharmacol Ther. 2014;95(1):78-88
    • (2014) Clin Pharmacol Ther , vol.95 , Issue.1 , pp. 78-88
    • Au, J.S.1    Pockros, P.J.2
  • 14
    • 84877905656 scopus 로고    scopus 로고
    • Hepatitis C therapy with HCV NS5B polymerase inhibitors
    • Soriano V, Vispo E, Mendoza C, et al Hepatitis C therapy with HCV NS5B polymerase inhibitors. Expert Opin Pharmacother. 2013;14:1161-1170
    • (2013) Expert Opin Pharmacother , vol.14 , pp. 1161-1170
    • Soriano, V.1    Vispo, E.2    Mendoza, C.3
  • 15
    • 81855220325 scopus 로고    scopus 로고
    • The therapeutic approaches for hepatitis C virus: Protease inhibitors and polymerase inhibitors
    • Kwo PY, Vinayek R. The therapeutic approaches for hepatitis C virus: protease inhibitors and polymerase inhibitors. Gut Liver. 2011;5(4):406-417
    • (2011) Gut Liver , vol.5 , Issue.4 , pp. 406-417
    • Kwo, P.Y.1    Vinayek, R.2
  • 16
    • 84881314351 scopus 로고    scopus 로고
    • Novel therapies for hepatitis C-one pill fits all?
    • Manns MP, Von Hahn T. Novel therapies for hepatitis C-one pill fits all?. Nat Rev Drug Discov. 2013;12 (8):595-610
    • (2013) Nat Rev Drug Discov , vol.12 , Issue.8 , pp. 595-610
    • Manns, M.P.1    Von Hahn, T.2
  • 17
    • 84874242508 scopus 로고    scopus 로고
    • Preclinical potency, pharmacokinetic and ADME characterization of ABT-333,a novel non-nucleoside HCV polymerase inhibitor
    • Maring C, Wagner R, Hutchinson D, et al. Preclinical potency, pharmacokinetic and ADME characterization of ABT-333,a novel non-nucleoside HCV polymerase inhibitor. J Hepatol. 2009;50:S347-S
    • (2009) J Hepatol , vol.50 , pp. S347-S
    • Maring, C.1    Wagner, R.2    Hutchinson, D.3
  • 18
    • 84899106124 scopus 로고    scopus 로고
    • Retreatment of HCV with ABT-450/rombitasv and dasabuvir with ribavirin
    • Zeuzem S, Jacobson IM, Baykal T, et al. Retreatment of HCV with ABT-450/rombitasv and dasabuvir with ribavirin. N Engl J Med. 2014;370(17):1604-1614
    • (2014) N Engl J Med , vol.370 , Issue.17 , pp. 1604-1614
    • Zeuzem, S.1    Jacobson, I.M.2    Baykal, T.3
  • 19
    • 75149116931 scopus 로고    scopus 로고
    • Treatment-naïve, HCV genotype 1-infected subjects show significantly greater HCV RNA decreases when treated with 28 days of ABT-333 plus peg interferon and ribavirin compared to peg interferon and ribavirin alone
    • Rodriguez-Torres M, Lawitz E, Cohen D. Treatment-naïve, HCV genotype 1-infected subjects show significantly greater HCV RNA decreases when treated with 28 days of ABT-333 plus peg interferon and ribavirin compared to peg interferon and ribavirin alone. Hepatology. 2009;50(Suppl 4):91A
    • (2009) Hepatology , vol.50 , Issue.4 , pp. 91A
    • Rodriguez-Torres, M.1    Lawitz, E.2    Cohen, D.3
  • 20
    • 84901036125 scopus 로고    scopus 로고
    • ABT-450/r-ombitasvir and Dasabuvir with ribavirin for hepatitis C with cirrhosis
    • Poordad F, Hezode C, Trinh R, et al. ABT-450/r-ombitasvir and Dasabuvir with ribavirin for hepatitis C with cirrhosis. N Engl J Med. 2014;370(21):1973-1982
    • (2014) N Engl J Med , vol.370 , Issue.21 , pp. 1973-1982
    • Poordad, F.1    Hezode, C.2    Trinh, R.3
  • 21
    • 84919360641 scopus 로고    scopus 로고
    • An interferon-free antiviral regimen for HCV after liver transplantation
    • Kwo PY, Mantry PS, Coakley E, et al. An interferon-free antiviral regimen for HCV after liver transplantation. N Engl J Med. 2014;371:2375-2382
    • (2014) N Engl J Med , vol.371 , pp. 2375-2382
    • Kwo, P.Y.1    Mantry, P.S.2    Coakley, E.3
  • 22
    • 84901044326 scopus 로고    scopus 로고
    • ABT-450/r-Ombitasvir and Dasabuvir with or without ribavirin for HCV
    • PEARL III and IV
    • Ferenci P, et al. ABT-450/r-Ombitasvir and Dasabuvir with or without ribavirin for HCV. N Engl J Med. 2014;370(21):1983-1992. PEARL III and IV
    • (2014) N Engl J Med , vol.370 , Issue.21 , pp. 1983-1992
    • Ferenci, P.1
  • 23
    • 84922849776 scopus 로고    scopus 로고
    • PEARL III: 12 weeks of abt-450/r/267 + abt-333 achieved svr in 99% of 419 treatment-naive hcv genotype 1binfected adults with or without ribavirin
    • Ferenci P, Nyberg A, Enayati P, et al. PEARL III: 12 weeks of ABT-450/R/267 + ABT-333 achieved SVR in 99% of 419 treatment-naive HCV genotype 1Binfected adults with or without ribavirin. J Hepatol. 2014;60(1):S527
    • (2014) J Hepatol , vol.60 , Issue.1 , pp. S527
    • Ferenci, P.1    Nyberg, A.2    Enayati, P.3
  • 24
    • 84899068302 scopus 로고    scopus 로고
    • Treatment of HCV with ABT-450/r-Ombitasvir and dasabuvir with ribavirin
    • Feld JJ, Kowdley KV, Coakley E, et al Treatment of HCV with ABT-450/r-Ombitasvir and dasabuvir with ribavirin. N Engl J Med. 2014;370(17):1594-1603
    • (2014) N Engl J Med , vol.370 , Issue.17 , pp. 1594-1603
    • Feld, J.J.1    Kowdley, K.V.2    Coakley, E.3
  • 25
    • 84931582726 scopus 로고    scopus 로고
    • 12-week efficacy and safety of ABT-072 or ABT-333 with Pegylated interferon + ribavirin, following 3-day monotherapy in genotype 1 HCV infected treatment-naive subjects [abstract1329]
    • 17-20 February ; Bangkok, Thailand
    • Gaultier I, Cohen D, Dumas E, et al. 12-week efficacy and safety of ABT-072 or ABT-333 with Pegylated interferon + ribavirin, following 3-day monotherapy in genotype 1 HCV infected treatment-naive subjects [abstract1329]. 21st Conference of the Asian Pacific Association for the Study of the Liver (APASL); 17-20 February2011; Bangkok, Thailand
    • (2011) 21st Conference of the Asian Pacific Association for the Study of the Liver (APASL)
    • Gaultier, I.1    Cohen, D.2    Dumas, E.3
  • 26
    • 84904614498 scopus 로고    scopus 로고
    • In vitro combinatory effect of HCV NS3/4A protease inhibitor ABT-450, NS5A inhibitor ABT-267 and non nucleoside NS5B polymerase inhibitor ABT-333
    • Pilot-Matias T, Koev G, Krishnan P, et al. In vitro combinatory effect of HCV NS3/4A protease inhibitor ABT-450, NS5A inhibitor ABT-267 and non nucleoside NS5B polymerase inhibitor ABT-333. J Hepatol. 2012;56:S338-S38
    • (2012) J Hepatol , vol.56 , pp. S338-S438
    • Pilot-Matias, T.1    Koev, G.2    Krishnan, P.3
  • 27
    • 84922869157 scopus 로고    scopus 로고
    • Safety and efficacy of Ombitasvir-450/r and dasabuvir and ribavirin in HCV/ HIV-1 co-infected patients receiving atazanavir or raltegravir ART regimens
    • Eron JJ, Lalezari J, Slim J, et al. Safety and efficacy of Ombitasvir-450/r and dasabuvir and ribavirin in HCV/ HIV-1 co-infected patients receiving atazanavir or raltegravir ART regimens. J Int AIDS Soc. 2014;17(4 Suppl 3):19500
    • (2014) J Int AIDS Soc , vol.17 , Issue.4 , pp. 19500
    • Eron, J.J.1    Lalezari, J.2    Slim, J.3
  • 28
    • 84871765489 scopus 로고    scopus 로고
    • Exploratory study of oral combination antiviral therapy for hepatitis C
    • Poordad F, Lawitz E, Kowdley KV, et al. Exploratory study of oral combination antiviral therapy for hepatitis C. N Engl J Med. 2013;368(1):45-53
    • (2013) N Engl J Med , vol.368 , Issue.1 , pp. 45-53
    • Poordad, F.1    Lawitz, E.2    Kowdley, K.V.3
  • 29
    • 84892591928 scopus 로고    scopus 로고
    • Phase 2b trial of interferon-free therapy for hepatitis C Virus genotype 1
    • Kowdley KV, Lawitz E, Poordad F, et al. Phase 2b trial of interferon-free therapy for hepatitis C Virus genotype 1. N Engl J Med. 2014;370(3):222-232
    • (2014) N Engl J Med , vol.370 , Issue.3 , pp. 222-232
    • Kowdley, K.V.1    Lawitz, E.2    Poordad, F.3


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