Reducing mortality in HIV-infected infants and achieving the 90-90-90 target through innovative diagnosis approaches

Journal of the International AIDS Society

Volumn 18, Issue , 2015, Pages

  Essajee, Shaffiq ^a   Vojnov, Lara ^b   Penazzato, Martina ^a   Jani, Ilesh ^c   Siberry, George K ^d   Fiscus, Susan A ^e   Markby, Jessica ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

^b CLINTON HEALTH ACCESS INITIATIVE   (United States)

^c INSTITUTO NACIONAL DE SAÚDE   (Mozambique)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Diagnosis; HIV; Infant; Point of care; SMS; Treatment

Indexed keywords

CHILD HEALTH CARE; COST EFFECTIVENESS ANALYSIS; EARLY DIAGNOSIS; HEALTH CARE ACCESS; HEALTH CARE FACILITY; HEALTH CARE SYSTEM; HIV TEST; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; INFANT MORTALITY; INFECTION PREVENTION; INTRAUTERINE INFECTION; LABORATORY TEST; MOBILE PHONE; MOLECULAR DIAGNOSIS; MOLECULAR DIAGNOSTICS; POINT OF CARE TESTING; PREVENTIVE HEALTH SERVICE; PRINTING; PRIORITY JOURNAL; REVIEW; SCALE UP; SYSTEMATIC REVIEW (TOPIC); VERTICAL TRANSMISSION; VIRUS DIAGNOSIS; CHILD; FEMALE; HIV INFECTIONS; MORTALITY;

CHILD; EARLY DIAGNOSIS; FEMALE; HIV INFECTIONS; HUMANS; INFANT;

EID: 84957073843     PISSN: None     EISSN: 17582652     Source Type: Journal    
DOI: 10.7448/IAS.18.7.20299     Document Type: Review

References (20)

1. 90-90-90: An ambitious treatment target to help end the AIDS epidemic. Geneva: UNAIDS [Internet]. 2014 [cited 2015 Sep 4]. Available from: Http: // www.unaids.org/en/resources/documents/2014/90-90-90
2. How AIDS changed everything - MDG6: 15 years, 15 lessons of hope from the AIDS response. Geneva: UNAIDS [Internet]. 2015 [cited 2015 Sep 4]. Available from: Http: //www.unaids.org/en/resources/documents/2015/MDG6-15years- 15lessonsfromtheAIDSresponse
3. Bourne DE, Thompson M, Brody LL, Cotton M, Draper B, Laubscher R, et al. Emergence of a peak in early infant mortality due to HIV/AIDS in South Africa. AIDS. 2009; 23(1): 101-6.
4. Innes S, Lazarus E, Otwombe K, Liberty A, Germanus R, Van Rensburg AJ, et al. Early severe HIV disease precedes early antiretroviral therapy in infants: Are we too late? J Int AIDS Soc. 2014; 17: 18914. doi: Http: //dx.doi.org/10.7448/ IAS.17.1.18914
5. Newell ML, Coovadia H, Cortina-Borja M, Rollins N, Gaillard P, Dabis F. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: A pooled analysis. Lancet. 2004; 364(9441): 1236-43.
6. Sherman GG, Lilian RR, Bhardwaj S, Candy S, Barron P. Laboratory information system data demonstrate successful implementation of the prevention of mother-to-child transmission programme in South Africa. S Afr Med J. 2014; 104(3 Suppl 1): 235-8.
7. World Health Organization. Global update on the health sector response to HIV, 2014. Geneva: World Health Organization; 2014. Update with GARPR 2015.
8. Chatterjee A, Tripathi S, Gass R, Hamunime N, Panha S, Kiyaga C, et al. Implementing services for early infant diagnosis (EID) of HIV: A comparative descriptive analysis of national programs in four countries. BMC Public Health. 2011; 11: 553. doi: Http: //dx.doi.org/10.1186/1471-2458-11-553
9. Sutcliffe CG, van Dijk JH, Hamangaba F, Mayani F, Moss WJ. Turnaround time for early infant HIV diagnosis in rural Zambia: A chart review. PLoS One. 2014; 9(1): E87028. doi: Http: //dx.doi.org/10.1371/journal.pone.0087028
10. Available from: Http: //www.prnewswire.com/news-releases/alere-receivesivd- ce-mark-for-alere-q-hiv-12-detect-assay-for-molecular-diagnosis-of-hiv-at-Thepoint- of-care-300042878.html
11. Available from: Http: //ir.cepheid.com/releasedetail.cfm?ReleaseID-906875
12. Piatek AS, Van Cleeff M, Alexander H, Coggin WL, Rehr M, Van Kampen S, et al. GeneXpert for TB diagnosis: Planned and purposeful implementation. Glob Health Sci Pract. 2013; 1(1): 18-23. doi: Http: //dx.doi.org/10.9745/GHSPD- 12-00004
13. Jani IV, Meggi B, Mabunda N, Vubil A, Sitoe NE, Tobaiwa O, et al. Accurate early infant HIV diagnosis in primary health clinics using a point-of-care nucleic acid test. J Acquir Immune Defic Syndr. 2014; 67(1): E1-4. doi: Http: //dx.doi. org/10.1097/QAI.0000000000000250
14. Hsiao N-Y, Kroon M, Dunning L, Myer L. Evaluation of the Alere q for pointof- care early infant HIV diagnosis in South Africa [CROI Abstract 34]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections. Top Antivir Med. 2015; 23(e-1): 15.
15. Kiyaga C, Sendagire H, Joseph E, McConnell I, Grosz J, Narayan V, et al. Uganda's new national laboratory sample transport system: A successful model for improving access to diagnostic services for early infant HIV diagnosis and other programs. PLoS One. 2013; 8(11): E78609. doi: Http: //dx.doi.org/10.1371/ journal.pone.0078609
16. Vojnov et al. Systematic review manuscript in preparation.
17. Cohn et al. Systematic review manuscript in preparation.
18. Marston M, Becquet R, Zaba B, Moulton LH, Gray G, Coovadia H, et al. Net survival of perinatally and postnatally HIV-infected children: A pooled analysis of individual data from sub-Saharan Africa. Int J Epidemiol. 2011; 40: 385-96. doi: Http: //dx.doi.org/10.1093/ije/dyq255
19. Lilian RR, Kalk E, Bhowan K, Berrie L, Carmona S, Technau K, et al. Early diagnosis of in utero and intrapartum HIV infection in infants prior to 6 weeks of age. J Clin Microbiol. 2012; 50(7): 2373-7. doi: Http: //dx.doi.org/10.1128/ JCM.00431-12
20. Penazzato M, Revill P, Prendergast AJ, Collins IJ, Walker S, Elyanu PJ, et al. Early infant diagnosis of HIV infection in low-income and middle-income countries: Does one size fit all? Lancet Infect Dis. 2014; 14(7): 650-5. doi: Http: //dx.doi.org/10.1016/S1473-3099(13)70262-7