-
1
-
-
0036238233
-
The aetiology of sporadic adult-onset ataxia
-
Abele M, Burk K, Schols L, Schwartz S, Besenthal I, Dichgans J, Zuhlke C, Riess O, Klockgether T (2002) The aetiology of sporadic adult-onset ataxia. Brain 125:961-968
-
(2002)
Brain
, vol.125
, pp. 961-968
-
-
Abele, M.1
Burk, K.2
Schols, L.3
Schwartz, S.4
Besenthal, I.5
Dichgans, J.6
Zuhlke, C.7
Riess, O.8
Klockgether, T.9
-
2
-
-
84855477917
-
The neuropathology, pathophysiology and genetics of multiple system atrophy
-
Ahmed Z, Asi YT, Sailer A, Lees AJ, Houlden H, Revesz T, Holton JL (2012) The neuropathology, pathophysiology and genetics of multiple system atrophy. Neuropathol Appl Neurobiol 38:4-24
-
(2012)
Neuropathol Appl Neurobiol
, vol.38
, pp. 4-24
-
-
Ahmed, Z.1
Asi, Y.T.2
Sailer, A.3
Lees, A.J.4
Houlden, H.5
Revesz, T.6
Holton, J.L.7
-
3
-
-
79251543343
-
Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice
-
Akundi RS, Huang Z, Eason J, Pandya JD, Zhi L, Cass WA, Sullivan PG, Bueler H (2011) Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice. PLoS One 6:e16038
-
(2011)
Plos One
, vol.6
-
-
Akundi, R.S.1
Huang, Z.2
Eason, J.3
Pandya, J.D.4
Zhi, L.5
Cass, W.A.6
Sullivan, P.G.7
Bueler, H.8
-
4
-
-
70349578343
-
Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy
-
Al-Chalabi A, Durr A, Wood NW, Parkinson MH, Camuzat A, Hulot JS, Morrison KE, Renton A, Sussmuth SD, Landwehrmeyer BG, Ludolph A, Agid Y, Brice A, Leigh PN, Bensimon G (2009) Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy. PLoS One 4:e7114
-
(2009)
Plos One
, vol.4
-
-
Al-Chalabi, A.1
Durr, A.2
Wood, N.W.3
Parkinson, M.H.4
Camuzat, A.5
Hulot, J.S.6
Morrison, K.E.7
Renton, A.8
Sussmuth, S.D.9
Landwehrmeyer, B.G.10
Ludolph, A.11
Agid, Y.12
Brice, A.13
Leigh, P.N.14
Bensimon, G.15
-
5
-
-
0035847186
-
Alpha-synuclein-positive structures in cases with sporadic Alzheimer’s disease: Morphology and its relationship to tau aggregation
-
Arai Y, Yamazaki M, Mori O, Muramatsu H, Asano G, Katayama Y (2001) Alpha-synuclein-positive structures in cases with sporadic Alzheimer’s disease: morphology and its relationship to tau aggregation. Brain Res 888:287-296
-
(2001)
Brain Res
, vol.888
, pp. 287-296
-
-
Arai, Y.1
Yamazaki, M.2
Mori, O.3
Muramatsu, H.4
Asano, G.5
Katayama, Y.6
-
6
-
-
33746894526
-
Spatial topography of the neurofibrillary tangles in cortical and subcortical regions in progressive supranuclear palsy
-
Armstrong RA et al (2006) Spatial topography of the neurofibrillary tangles in cortical and subcortical regions in progressive supranuclear palsy. Park Rel Disord 12:356-362
-
(2006)
Park Rel Disord
, vol.12
, pp. 356-362
-
-
Armstrong, R.A.1
-
7
-
-
33646175559
-
P25alpha immunoreac-tive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy
-
Baker KG, Huang Y, Mc Cann H, Gai WP, Jensen PH, Halliday GM (2006) P25alpha immunoreac-tive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy. Acta Neuropathol 111:193-195
-
(2006)
Acta Neuropathol
, vol.111
, pp. 193-195
-
-
Baker, K.G.1
Huang, Y.2
Mc Cann, H.3
Gai, W.P.4
Jensen, P.H.5
Halliday, G.M.6
-
8
-
-
0028845756
-
Arg296 to Cys296 polymorphism in exon 6 of cytochrome P-450-2D6 (CYP2D6) is not associated with multiple system atrophy
-
Bandmann O, Wenning GK, Quinn NP, Harding AE (1995) Arg296 to Cys296 polymorphism in exon 6 of cytochrome P-450-2D6 (CYP2D6) is not associated with multiple system atrophy. J Neurol Neurosurg Psychiatry 59:557
-
(1995)
J Neurol Neurosurg Psychiatry
, vol.59
, pp. 557
-
-
Bandmann, O.1
Wenning, G.K.2
Quinn, N.P.3
Harding, A.E.4
-
9
-
-
0031454722
-
Multiple-system atrophy is genetically distinct from identified inherited causes of spinocerebellar degeneration
-
Bandmann O, Sweeney MG, Daniel SE, Wenning GK, Quinn N, Marsden CD, Wood NW (1997) Multiple-system atrophy is genetically distinct from identified inherited causes of spinocerebellar degeneration. Neurology 49:1598-1604
-
(1997)
Neurology
, vol.49
, pp. 1598-1604
-
-
Bandmann, O.1
Sweeney, M.G.2
Daniel, S.E.3
Wenning, G.K.4
Quinn, N.5
Marsden, C.D.6
Wood, N.W.7
-
10
-
-
74149094597
-
[11C]-PK11195 PET: Quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson’s disease?
-
Bartels AL, Willemsen AT, Doorduin J, de Vries EF, Dierckx RA, Leenders KL (2010) [11C]-PK11195 PET: quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson’s disease? Parkinsonism Relat Disord 16:57-59
-
(2010)
Parkinsonism Relat Disord
, vol.16
, pp. 57-59
-
-
Bartels, A.L.1
Willemsen, A.T.2
Doorduin, J.3
De Vries, E.F.4
Dierckx, R.A.5
Leenders, K.L.6
-
11
-
-
0028879044
-
Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: Implication of phosphoprotein phosphatase involvement
-
Baum L, Seger R, Woodgett JR, Kawabata S, Maruyama K, Koyama M, Silver J, Saitoh T (1995) Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: implication of phosphoprotein phosphatase involvement. Brain Res Mol Brain Res 34:1-17
-
(1995)
Brain Res Mol Brain Res
, vol.34
, pp. 1-17
-
-
Baum, L.1
Seger, R.2
Woodgett, J.R.3
Kawabata, S.4
Maruyama, K.5
Koyama, M.6
Silver, J.7
Saitoh, T.8
-
12
-
-
84858677969
-
Alpha-synuclein alters toll-like receptor expression
-
Beraud D, Twomey M, Bloom B, Mittereder A, Ton V, Neitzke K, Chasovskikh S, Mhyre TR, Maguire-Zeiss KA (2011) Alpha-synuclein alters toll-like receptor expression. Front Neurosci 5:80
-
(2011)
Front Neurosci
, vol.5
, pp. 80
-
-
Beraud, D.1
Twomey, M.2
Bloom, B.3
Mittereder, A.4
Ton, V.5
Neitzke, K.6
Chasovskikh, S.7
Mhyre, T.R.8
Maguire-Zeiss, K.A.9
-
13
-
-
84874654334
-
Microglial activation and antioxidant responses induced by the Parkinson’s disease protein alpha-synuclein
-
Beraud D, Hathaway HA, Trecki J, Chasovskikh S, Johnson DA, Johnson JA, Federoff HJ, Shimoji M, Mhyre TR, Maguire-Zeiss KA (2013) Microglial activation and antioxidant responses induced by the Parkinson’s disease protein alpha-synuclein. J Neuroimmune Pharmacol 8:94-117
-
(2013)
J Neuroimmune Pharmacol
, vol.8
, pp. 94-117
-
-
Beraud, D.1
Hathaway, H.A.2
Trecki, J.3
Chasovskikh, S.4
Johnson, D.A.5
Johnson, J.A.6
Federoff, H.J.7
Shimoji, M.8
Mhyre, T.R.9
Maguire-Zeiss, K.A.10
-
14
-
-
0029838005
-
Glial and neuronal cytoplasmic inclusions in familial olivopontocerebellar atrophy
-
Berciano J, Ferrer I (1996) Glial and neuronal cytoplasmic inclusions in familial olivopontocerebellar atrophy. Ann Neurol 40:819-820
-
(1996)
Ann Neurol
, vol.40
, pp. 819-820
-
-
Berciano, J.1
Ferrer, I.2
-
15
-
-
20844458601
-
Glial cell cytoplasmic inclusions in SCA2 do not express alpha-synuclein
-
Berciano J, Ferrer I (2005) Glial cell cytoplasmic inclusions in SCA2 do not express alpha-synuclein. J Neurol 252:742-744
-
(2005)
J Neurol
, vol.252
, pp. 742-744
-
-
Berciano, J.1
Ferrer, I.2
-
16
-
-
33644947582
-
Very late-onset Friedreich’s ataxia with minimal GAA1 expansion mimicking multiple system atrophy of cerebellar type
-
Berciano J, Infante J, Garcia A, Polo JM, Volpini V, Combarros O (2005) Very late-onset Friedreich’s ataxia with minimal GAA1 expansion mimicking multiple system atrophy of cerebellar type. Mov Disord 20:1643-1645
-
(2005)
Mov Disord
, vol.20
, pp. 1643-1645
-
-
Berciano, J.1
Infante, J.2
Garcia, A.3
Polo, J.M.4
Volpini, V.5
Combarros, O.6
-
17
-
-
33747769942
-
Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers
-
Beyer K (2006) Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers. Acta Neuropathol 112:237-251
-
(2006)
Acta Neuropathol
, vol.112
, pp. 237-251
-
-
Beyer, K.1
-
18
-
-
35848966786
-
Protein aggregation mechanisms in synucleinopathies: Commonalities and differences
-
Beyer K, Ariza A (2007) Protein aggregation mechanisms in synucleinopathies: commonalities and differences. J Neuropathol Exp Neurol 66:965-974
-
(2007)
J Neuropathol Exp Neurol
, vol.66
, pp. 965-974
-
-
Beyer, K.1
Ariza, A.2
-
19
-
-
79952900675
-
Mutational analysis of parkin and PINK1 in multiple system atrophy
-
Brooks JA, Houlden H, Melchers A, Islam AJ, Ding J, Li A, Paudel R, Revesz T, Holton JL, Wood N, Lees A, Singleton AB, Scholz SW (2011) Mutational analysis of parkin and PINK1 in multiple system atrophy. Neurobiol Aging 32(548):e5-e7
-
(2011)
Neurobiol Aging
, vol.32
, Issue.548
-
-
Brooks, J.A.1
Houlden, H.2
Melchers, A.3
Islam, A.J.4
Ding, J.5
Li, A.6
Paudel, R.7
Revesz, T.8
Holton, J.L.9
Wood, N.10
Lees, A.11
Singleton, A.B.12
Scholz, S.W.13
-
20
-
-
52449117926
-
Research in motion: The enigma of Parkinson’s disease pathology spread. Nat
-
Brundin P, Li JY, Holton JL, Lindvall O, Revesz T (2008) Research in motion: the enigma of Parkinson’s disease pathology spread. Nat Rev Neurosci 9:741-745
-
(2008)
Rev Neurosci
, vol.9
, pp. 741-745
-
-
Brundin, P.1
Li, J.Y.2
Holton, J.L.3
Lindvall, O.4
Revesz, T.5
-
21
-
-
0033813956
-
-
Mov Disord
-
Buervenich S, Sydow O, Carmine A, Zhang Z, Anvret M, Olson L (2000) Alcohol dehydrogenase alleles in Parkinson’s disease. Mov Disord 15:813-818
-
(2000)
Alcohol Dehydrogenase Alleles in Parkinson’s Disease
, vol.15
, pp. 813-818
-
-
Buervenich, S.1
Sydow, O.2
Carmine, A.3
Zhang, Z.4
Anvret, M.5
Olson, L.6
-
22
-
-
0031564828
-
Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer’s disease
-
Cairns NJ, Atkinson PF, Hanger DP, Anderton BH, Daniel SE, Lantos PL (1997) Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer’s disease. Neurosci Lett 230:49-52
-
(1997)
Neurosci Lett
, vol.230
, pp. 49-52
-
-
Cairns, N.J.1
Atkinson, P.F.2
Hanger, D.P.3
Erton, B.H.4
Daniel, S.E.5
Lantos, P.L.6
-
23
-
-
0035163412
-
The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson’s disease
-
Campbell BC, McLean CA, Culvenor JG, Gai WP, Blumbergs PC, Jakala P, Beyreuther K, Masters CL, Li QX (2001) The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson’s disease. J Neurochem 76:87-96
-
(2001)
J Neurochem
, vol.76
, pp. 87-96
-
-
Campbell, B.C.1
Mc Lean, C.A.2
Culvenor, J.G.3
Gai, W.P.4
Blumbergs, P.C.5
Jakala, P.6
Beyreuther, K.7
Masters, C.L.8
Li, Q.X.9
-
24
-
-
4644290985
-
Alpha-synuclein locus duplication as a cause of familial Parkinson’s disease
-
Chartier-Harlin MC, Kachergus J, Roumier C, Mouroux V, Douay X, Lincoln S, Levecque C, Larvor L, Andrieux J, Hulihan M, Waucquier N, Defebvre L, Amouyel P, Farrer M, Destee A (2004) Alpha-synuclein locus duplication as a cause of familial Parkinson’s disease. Lancet 364:1167-1169
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Rieux, J.9
Hulihan, M.10
Waucquier, N.11
Defebvre, L.12
Amouyel, P.13
Farrer, M.14
Destee, A.15
-
25
-
-
4243732903
-
Mutation screening in the a-synuclein gene in MSA
-
Chen R, Forno L, Dimonte D, Chan P, AL E (1999) Mutation screening in the a-synuclein gene in MSA. Parkinsonism Relat Disord 5:S28
-
(1999)
Parkinsonism Relat Disord
, vol.5
-
-
Chen, R.1
Forno, L.2
Dimonte, D.3
Chan, P.4
Al, E.5
-
26
-
-
62449132771
-
Nrf2-Mediated neuroprotection in the MPTP mouse model of Parkinson’s disease: Critical role for the astrocyte
-
Chen PC, Vargas MR, Pani AK, Smeyne RJ, Johnson DA, Kan YW, Johnson JA (2009) Nrf2-Mediated neuroprotection in the MPTP mouse model of Parkinson’s disease: critical role for the astrocyte. Proc Natl Acad Sci U S A 106:2933-2938
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2933-2938
-
-
Chen, P.C.1
Vargas, M.R.2
Pani, A.K.3
Smeyne, R.J.4
Johnson, D.A.5
Kan, Y.W.6
Johnson, J.A.7
-
27
-
-
0041321406
-
Variations in the dopamine beta-hydroxylase gene are not associated with the autonomic disorders, pure autonomic failure, or multiple system atrophy
-
Cho S, Kim CH, Cubells JF, Zabetian CP, Hwang DY, Kim JW, Cohen BM, Biaggioni I, Robertson D, Kim KS (2003) Variations in the dopamine beta-hydroxylase gene are not associated with the autonomic disorders, pure autonomic failure, or multiple system atrophy. Am J Med Genet A 120A:234-236
-
(2003)
Am J Med Genet A
, vol.120A
, pp. 234-236
-
-
Cho, S.1
Kim, C.H.2
Cubells, J.F.3
Zabetian, C.P.4
Hwang, D.Y.5
Kim, J.W.6
Cohen, B.M.7
Biaggioni, I.8
Robertson, D.9
Kim, K.S.10
-
28
-
-
55049083785
-
Spinocerebellar ataxia type 12 was not found in Korean Parkinsonian patients
-
Cho JW, Kim SY, Park SS, Jeon BS (2008) Spinocerebellar ataxia type 12 was not found in Korean Parkinsonian patients. Can J Neurol Sci 35:488-490
-
(2008)
Can J Neurol Sci
, vol.35
, pp. 488-490
-
-
Cho, J.W.1
Kim, S.Y.2
Park, S.S.3
Jeon, B.S.4
-
29
-
-
73449090031
-
The G2019S LRRK2 mutation is rare in Korean patients with Parkinson’s disease and multiple system atrophy
-
Cho JW, Kim SY, Park SS, Jeon BS (2009) The G2019S LRRK2 mutation is rare in Korean patients with Parkinson’s disease and multiple system atrophy. J Clin Neurol 5:29-32
-
(2009)
J Clin Neurol
, vol.5
, pp. 29-32
-
-
Cho, J.W.1
Kim, S.Y.2
Park, S.S.3
Jeon, B.S.4
-
31
-
-
1342347397
-
Interleukin-1A (-889) genetic polymorphism increases the risk of multiple system atrophy
-
Combarros O, Infante J, Llorca J, Berciano J (2003) Interleukin-1A (-889) genetic polymorphism increases the risk of multiple system atrophy. Mov Disord 18:1385-1386
-
(2003)
Mov Disord
, vol.18
, pp. 1385-1386
-
-
Combarros, O.1
Infante, J.2
Llorca, J.3
Berciano, J.4
-
32
-
-
69149089854
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
-
Desplats P, Lee HJ, Bae EJ, Patrick C, Rockenstein E, Crews L, Spencer B, Masliah E, Lee SJ (2009) Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci U S A 106:13010-13015
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13010-13015
-
-
Desplats, P.1
Lee, H.J.2
Bae, E.J.3
Patrick, C.4
Rockenstein, E.5
Crews, L.6
Spencer, B.7
Masliah, E.8
Lee, S.J.9
-
33
-
-
0032833653
-
Widespread alterations of alpha-synuclein in multiple system atrophy
-
Dickson DW, Liu W, Hardy J, Farrer M, Mehta N, Uitti R, Mark M, Zimmerman T, Golbe L, Sage J, Sima A, D’Amato C, Albin R, Gilman S, Yen SH (1999) Widespread alterations of alpha-synuclein in multiple system atrophy. Am J Pathol 155:1241-1251
-
(1999)
Am J Pathol
, vol.155
, pp. 1241-1251
-
-
Dickson, D.W.1
Liu, W.2
Hardy, J.3
Farrer, M.4
Mehta, N.5
Uitti, R.6
Mark, M.7
Zimmerman, T.8
Golbe, L.9
Sage, J.10
Sima, A.11
D’amato, C.12
Albin, R.13
Gilman, S.14
Yen, S.H.15
-
34
-
-
0041912772
-
Regionally specific effects of BDNF on oligodendrocytes
-
Du Y, Fischer TZ, Lee LN, Lercher LD, Dreyfus CF (2003) Regionally specific effects of BDNF on oligodendrocytes. Dev Neurosci 25:116-126
-
(2003)
Dev Neurosci
, vol.25
, pp. 116-126
-
-
Du, Y.1
Fischer, T.Z.2
Lee, L.N.3
Lercher, L.D.4
Dreyfus, C.F.5
-
35
-
-
0033678217
-
Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies
-
Duda JE, Giasson BI, Chen Q, Gur TL, Hurtig HI, Stern MB, Gollomp SM, Ischiropoulos H, Lee VM, Trojanowski JQ (2000a) Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies. Am J Pathol 157:1439-1445
-
(2000)
Am J Pathol
, vol.157
, pp. 1439-1445
-
-
Duda, J.E.1
Giasson, B.I.2
Chen, Q.3
Gur, T.L.4
Hurtig, H.I.5
Stern, M.B.6
Gollomp, S.M.7
Ischiropoulos, H.8
Lee, V.M.9
Trojanowski, J.Q.10
-
36
-
-
0033800039
-
Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy
-
Duda JE, Giasson BI, Gur TL, Montine TJ, Robertson D, Biaggioni I, Hurtig HI, Stern MB, Gollomp SM, Grossman M, Lee VM, Trojanowski JQ (2000b) Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy. J Neuropathol Exp Neurol 59:830-841
-
(2000)
J Neuropathol Exp Neurol
, vol.59
, pp. 830-841
-
-
Duda, J.E.1
Giasson, B.I.2
Gur, T.L.3
Montine, T.J.4
Robertson, D.5
Biaggioni, I.6
Hurtig, H.I.7
Stern, M.B.8
Gollomp, S.M.9
Grossman, M.10
Lee, V.M.11
Trojanowski, J.Q.12
-
37
-
-
14844284632
-
False-positive SCA8 gene test in a patient with pathologically proven multiple system atrophy
-
Factor SA, Qian J, Lava NS, Hubbard JD, Payami H (2005) False-positive SCA8 gene test in a patient with pathologically proven multiple system atrophy. Ann Neurol 57:462-463
-
(2005)
Ann Neurol
, vol.57
, pp. 462-463
-
-
Factor, S.A.1
Qian, J.2
Lava, N.S.3
Hubbard, J.D.4
Payami, H.5
-
38
-
-
79958091447
-
Glial dysfunction in the pathogenesis of alpha-synucleinopathies: Emerging concepts
-
Fellner L, Jellinger KA, Wenning GK, Stefanova N (2011) Glial dysfunction in the pathogenesis of alpha-synucleinopathies: emerging concepts. Acta Neuropathol 121:675-693
-
(2011)
Acta Neuropathol
, vol.121
, pp. 675-693
-
-
Fellner, L.1
Jellinger, K.A.2
Wenning, G.K.3
Stefanova, N.4
-
39
-
-
77954400088
-
Alpha-synuclein mediates alterations in membrane conductance: A potential role for alpha-synuclein oligomers in cell vulnerability
-
Feng LR, Federoff HJ, Vicini S, Maguire-Zeiss KA (2010) Alpha-synuclein mediates alterations in membrane conductance: a potential role for alpha-synuclein oligomers in cell vulnerability. Eur J Neurosci 32:10-17
-
(2010)
Eur J Neurosci
, vol.32
, pp. 10-17
-
-
Feng, L.R.1
Federoff, H.J.2
Vicini, S.3
Maguire-Zeiss, K.A.4
-
40
-
-
26444544352
-
Alpha-synuclein transgenic mice: Relevance to multiple system atrophy
-
Fillon G, Kahle PJ (2005) Alpha-synuclein transgenic mice: relevance to multiple system atrophy. Mov Disord 20(Suppl 12):S64-S66
-
(2005)
Mov Disord
, vol.20
, pp. S64-S66
-
-
Fillon, G.1
Kahle, P.J.2
-
41
-
-
77249133010
-
Prion-like mechanisms in neurodegenerative diseases
-
Frost B, Diamond MI (2010) Prion-like mechanisms in neurodegenerative diseases. Nat Rev Neurosci 11:155-159
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 155-159
-
-
Frost, B.1
Diamond, M.I.2
-
42
-
-
34147109175
-
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication
-
Fuchs J, Nilsson C, Kachergus J, Munz M, Larsson EM, Schule B, Langston JW, Middleton FA, Ross OA, Hulihan M, Gasser T, Farrer MJ (2007) Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication. Neurology 68:916-922
-
(2007)
Neurology
, vol.68
, pp. 916-922
-
-
Fuchs, J.1
Nilsson, C.2
Kachergus, J.3
Munz, M.4
Larsson, E.M.5
Schule, B.6
Langston, J.W.7
Middleton, F.A.8
Ross, O.A.9
Hulihan, M.10
Gasser, T.11
Farrer, M.J.12
-
43
-
-
0036174010
-
Alpha-synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, Goldberg MS, Shen J, Takio K, Iwatsubo T (2002) Alpha-synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol 4:160-164
-
(2002)
Nat Cell Biol
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.S.6
Shen, J.7
Takio, K.8
Iwatsubo, T.9
-
44
-
-
23744514315
-
Alpha-1-antichymotrypsin gene polymorphism and susceptibility to multiple system atrophy (MSA)
-
Furiya Y, Hirano M, Kurumatani N, Nakamuro T, Matsumura R, Futamura N, Ueno S (2005) Alpha-1-antichymotrypsin gene polymorphism and susceptibility to multiple system atrophy (MSA). Brain Res Mol Brain Res 138:178-181
-
(2005)
Brain Res Mol Brain Res
, vol.138
, pp. 178-181
-
-
Furiya, Y.1
Hirano, M.2
Kurumatani, N.3
Nakamuro, T.4
Matsumura, R.5
Futamura, N.6
Ueno, S.7
-
45
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM (2000) Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science 290:985-989
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
46
-
-
0030040304
-
Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions
-
Gilman S, Sima AA, Junck L, Kluin KJ, Koeppe RA, Lohman ME, Little R (1996) Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions. Ann Neurol 39:241-255
-
(1996)
Ann Neurol
, vol.39
, pp. 241-255
-
-
Gilman, S.1
Sima, A.A.2
Junck, L.3
Kluin, K.J.4
Koeppe, R.A.5
Lohman, M.E.6
Little, R.7
-
47
-
-
0033837087
-
Evolution of sporadic olivopontocerebellar atrophy into multiple system atrophy
-
Gilman S, Little R, Johanns J, Heumann M, Kluin KJ, Junck L, Koeppe RA, An H (2000) Evolution of sporadic olivopontocerebellar atrophy into multiple system atrophy. Neurology 55:527-532
-
(2000)
Neurology
, vol.55
, pp. 527-532
-
-
Gilman, S.1
Little, R.2
Johanns, J.3
Heumann, M.4
Kluin, K.J.5
Junck, L.6
Koeppe, R.A.7
An, H.8
-
48
-
-
52449086856
-
Second consensus statement on the diagnosis of multiple system atrophy
-
Gilman S, Wenning GK, Low PA, Brooks DJ, Mathias CJ, Trojanowski JQ, Wood NW, Colosimo C, Durr A, Fowler CJ, Kaufmann H, Klockgether T, Lees A, Poewe W, Quinn N, Revesz T, Robertson D, Sandroni P, Seppi K, Vidailhet M (2008) Second consensus statement on the diagnosis of multiple system atrophy. Neurology 71:670-676
-
(2008)
Neurology
, vol.71
, pp. 670-676
-
-
Gilman, S.1
Wenning, G.K.2
Low, P.A.3
Brooks, D.J.4
Mathias, C.J.5
Trojanowski, J.Q.6
Wood, N.W.7
Colosimo, C.8
Durr, A.9
Fowler, C.J.10
Kaufmann, H.11
Klockgether, T.12
Lees, A.13
Poewe, W.14
Quinn, N.15
Revesz, T.16
Robertson, D.17
Sandroni, P.18
Seppi, K.19
Vidailhet, M.20
more..
-
49
-
-
33748304674
-
Glucocerebrosidase mutations are an important risk factor for Lewy body disorders
-
Goker-Alpan O, Giasson BI, Eblan MJ, Nguyen J, Hurtig HI, Lee VM, Trojanowski JQ, Sidransky E (2006) Glucocerebrosidase mutations are an important risk factor for Lewy body disorders. Neurology 67:908-910
-
(2006)
Neurology
, vol.67
, pp. 908-910
-
-
Goker-Alpan, O.1
Giasson, B.I.2
Eblan, M.J.3
Nguyen, J.4
Hurtig, H.I.5
Lee, V.M.6
Trojanowski, J.Q.7
Sidransky, E.8
-
50
-
-
0034069848
-
Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p
-
Gwinn-Hardy K, Mehta ND, Farrer M, Maraganore D, Muenter M, Yen SH, Hardy J, Dickson DW (2000) Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p. Acta Neuropathol 99:663-672
-
(2000)
Acta Neuropathol
, vol.99
, pp. 663-672
-
-
Gwinn-Hardy, K.1
Mehta, N.D.2
Farrer, M.3
Maraganore, D.4
Muenter, M.5
Yen, S.H.6
Hardy, J.7
Dickson, D.W.8
-
51
-
-
0032951487
-
Multiple system atrophy: The putative causative role of environmental toxins
-
Hanna PA, Jankovic J, Kirkpatrick JB (1999) Multiple system atrophy: the putative causative role of environmental toxins. Arch Neurol 56:90-94
-
(1999)
Arch Neurol
, vol.56
, pp. 90-94
-
-
Hanna, P.A.1
Jankovic, J.2
Kirkpatrick, J.B.3
-
52
-
-
79551519276
-
Alpha-synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
-
Hansen C, Angot E, Bergstrom AL, Steiner JA, Pieri L, Paul G, Outeiro TF, Melki R, Kallunki P, Fog K, Li JY, Brundin P (2011) Alpha-synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J Clin Invest 121:715-725
-
(2011)
J Clin Invest
, vol.121
, pp. 715-725
-
-
Hansen, C.1
Angot, E.2
Bergstrom, A.L.3
Steiner, J.A.4
Pieri, L.5
Paul, G.6
Outeiro, T.F.7
Melki, R.8
Kallunki, P.9
Fog, K.10
Li, J.Y.11
Brundin, P.12
-
53
-
-
34247168008
-
Multiplex families with multiple system atrophy
-
Hara K, Momose Y, Tokiguchi S, Shimohata M, Terajima K, Onodera O, Kakita A, Yamada M, Takahashi H, Hirasawa M, Mizuno Y, Ogata K, Goto J, Kanazawa I, Nishizawa M, Tsuji S (2007) Multiplex families with multiple system atrophy. Arch Neurol 64:545-551
-
(2007)
Arch Neurol
, vol.64
, pp. 545-551
-
-
Hara, K.1
Momose, Y.2
Tokiguchi, S.3
Shimohata, M.4
Terajima, K.5
Onodera, O.6
Kakita, A.7
Yamada, M.8
Takahashi, H.9
Hirasawa, M.10
Mizuno, Y.11
Ogata, K.12
Goto, J.13
Kanazawa, I.14
Nishizawa, M.15
Tsuji, S.16
-
54
-
-
84857008054
-
Microglia in the developing brain: A potential target with lifetime effects
-
Harry GJ, Kraft AD (2012) Microglia in the developing brain: a potential target with lifetime effects. Neurotoxicology 33:191-206
-
(2012)
Neurotoxicology
, vol.33
, pp. 191-206
-
-
Harry, G.J.1
Kraft, A.D.2
-
55
-
-
78649634791
-
Role of TPPP/p25 on alpha-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy
-
Hasegawa T, Baba T, Kobayashi M, Konno M, Sugeno N, Kikuchi A, Itoyama Y, Takeda A (2010) Role of TPPP/p25 on alpha-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy. Neurochem Int 57:857-866
-
(2010)
Neurochem Int
, vol.57
, pp. 857-866
-
-
Hasegawa, T.1
Baba, T.2
Kobayashi, M.3
Konno, M.4
Sugeno, N.5
Kikuchi, A.6
Itoyama, Y.7
Takeda, A.8
-
56
-
-
27844507620
-
UCHL-1 gene in multiple system atrophy: A haplotype tagging approach
-
Healy DG, Abou-Sleiman PM, Quinn N, Ahmadi KR, Ozawa T, Kamm C, Wullner U, Oertel WH, Burk K, Dupont E, Pellecchia MT, Tolosa E, Gasser T, Holton JL, Revesz T, Goldstein DB, Lees AJ, Wood NW (2005) UCHL-1 gene in multiple system atrophy: a haplotype tagging approach. Mov Disord 20:1338-1343
-
(2005)
Mov Disord
, vol.20
, pp. 1338-1343
-
-
Healy, D.G.1
Abou-Sleiman, P.M.2
Quinn, N.3
Ahmadi, K.R.4
Ozawa, T.5
Kamm, C.6
Wullner, U.7
Oertel, W.H.8
Burk, K.9
Dupont, E.10
Pellecchia, M.T.11
Tolosa, E.12
Gasser, T.13
Holton, J.L.14
Revesz, T.15
Goldstein, D.B.16
Lees, A.J.17
Wood, N.W.18
-
57
-
-
79951513184
-
Cerebrospinal fluid from patients with multiple system atrophy promotes in vitro alpha-synuclein fibril formation
-
Hirohata M, Ono K, Morinaga A, Ikeda T, Yamada M (2011) Cerebrospinal fluid from patients with multiple system atrophy promotes in vitro alpha-synuclein fibril formation. Neurosci Lett 491:48-52
-
(2011)
Neurosci Lett
, vol.491
, pp. 48-52
-
-
Hirohata, M.1
Ono, K.2
Morinaga, A.3
Ikeda, T.4
Yamada, M.5
-
58
-
-
0033890821
-
Alpha-synuclein promotes mitochondrial deficit and oxidative stress
-
Hsu LJ, Sagara Y, Arroyo A, Rockenstein E, Sisk A, Mallory M, Wong J, Takenouchi T, Hashimoto M, Masliah E (2000) Alpha-synuclein promotes mitochondrial deficit and oxidative stress. Am J Pathol 157:401-410
-
(2000)
Am J Pathol
, vol.157
, pp. 401-410
-
-
Hsu, L.J.1
Sagara, Y.2
Arroyo, A.3
Rockenstein, E.4
Sisk, A.5
Mallory, M.6
Wong, J.7
Takenouchi, T.8
Hashimoto, M.9
Masliah, E.10
-
59
-
-
81855204961
-
Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation
-
Hybertson BM, Gao B, Bose SK, Mc Cord JM (2011) Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation. Mol Aspects Med 32:234-246
-
(2011)
Mol Aspects Med
, vol.32
, pp. 234-246
-
-
Hybertson, B.M.1
Gao, B.2
Bose, S.K.3
Mc Cord, J.M.4
-
60
-
-
10644256410
-
Interleukin-8, intercellular adhesion molecule-1 and tumour necrosis factor-alpha gene polymorphisms and the risk for multiple system atrophy
-
Infante J, Llorca J, Berciano J, Combarros O (2005) Interleukin-8, intercellular adhesion molecule-1 and tumour necrosis factor-alpha gene polymorphisms and the risk for multiple system atrophy. J Neurol Sci 228:11-13
-
(2005)
J Neurol Sci
, vol.228
, pp. 11-13
-
-
Infante, J.1
Llorca, J.2
Berciano, J.3
Combarros, O.4
-
61
-
-
0030576564
-
Increased tau immunoreactivity in oligodendrocytes following human stroke and head injury
-
Irving EA, Nicoll J, Graham DI, Dewar D (1996) Increased tau immunoreactivity in oligodendrocytes following human stroke and head injury. Neurosci Lett 213:189-192
-
(1996)
Neurosci Lett
, vol.213
, pp. 189-192
-
-
Irving, E.A.1
Nicoll, J.2
Graham, D.I.3
Dewar, D.4
-
62
-
-
0030837090
-
Rapid alteration of tau in oligodendrocytes after focal ischemic injury in the rat: Involvement of free radicals
-
Irving EA, Yatsushiro K, Mc Culloch J, Dewar D (1997) Rapid alteration of tau in oligodendrocytes after focal ischemic injury in the rat: involvement of free radicals. J Cereb Blood Flow Metab 17:612-622
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, pp. 612-622
-
-
Irving, E.A.1
Yatsushiro, K.2
Mc Culloch, J.3
Dewar, D.4
-
63
-
-
0038389681
-
Oxidative modifications of alpha-synuclein
-
Ischiropoulos H (2003) Oxidative modifications of alpha-synuclein. Ann N Y Acad Sci 991:93-100
-
(2003)
Ann N Y Acad Sci
, vol.991
, pp. 93-100
-
-
Ischiropoulos, H.1
-
64
-
-
0028946508
-
A novel cytochrome P-450IID6 (CYPIID6) mutant gene associated with multiple system atrophy
-
Iwahashi K, Miyatake R, Tsuneoka Y, Matsuo Y, Ichikawa Y, Hosokawa K, Sato K, Hayabara T (1995) A novel cytochrome P-450IID6 (CYPIID6) mutant gene associated with multiple system atrophy. J Neurol Neurosurg Psychiatry 58:263-264
-
(1995)
J Neurol Neurosurg Psychiatry
, vol.58
, pp. 263-264
-
-
Iwahashi, K.1
Miyatake, R.2
Tsuneoka, Y.3
Matsuo, Y.4
Ichikawa, Y.5
Hosokawa, K.6
Sato, K.7
Hayabara, T.8
-
65
-
-
77953022133
-
Papp-Lantos inclusions and the pathogenesis of multiple system atrophy: An update
-
Jellinger KA, Lantos PL (2010) Papp-Lantos inclusions and the pathogenesis of multiple system atrophy: an update. Acta Neuropathol 119:657-667
-
(2010)
Acta Neuropathol
, vol.119
, pp. 657-667
-
-
Jellinger, K.A.1
Lantos, P.L.2
-
67
-
-
84855956157
-
Unusual tau in MSA
-
Jellinger K (2012a) Unusual tau in MSA. Neuropathology 32:110-111
-
(2012)
Neuropathology
, vol.32
, pp. 110-111
-
-
Jellinger, K.1
-
68
-
-
84864130246
-
The role of alpha-synuclein in neurodegeneration - an update
-
Jellinger KA (2012b) The role of alpha-synuclein in neurodegeneration - an update. Transl Neurosci 3:75-122
-
(2012)
Transl Neurosci
, vol.3
, pp. 75-122
-
-
Jellinger, K.A.1
-
69
-
-
52449131844
-
Analyses of copy number and mRNA expression level of the alpha-synuclein gene in multiple system atrophy
-
Jin H, Ishikawa K, Tsunemi T, Ishiguro T, Amino T, Mizusawa H (2008) Analyses of copy number and mRNA expression level of the alpha-synuclein gene in multiple system atrophy. J Med Dent Sci 55:145-153
-
(2008)
J Med Dent Sci
, vol.55
, pp. 145-153
-
-
Jin, H.1
Ishikawa, K.2
Tsunemi, T.3
Ishiguro, T.4
Amino, T.5
Mizusawa, H.6
-
70
-
-
0036319473
-
Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice
-
Johnson DA, Andrews GK, Xu W, Johnson JA (2002) Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice. J Neurochem 81:1233-1241
-
(2002)
J Neurochem
, vol.81
, pp. 1233-1241
-
-
Johnson, D.A.1
Rews, G.K.2
Xu, W.3
Johnson, J.A.4
-
71
-
-
0036304315
-
Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes
-
Kahle PJ, Neumann M, Ozmen L, Muller V, Jacobsen H, Spooren W, Fuss B, Mallon B, Macklin WB, Fujiwara H, Hasegawa M, Iwatsubo T, Kretzschmar HA, Haass C (2002) Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes. EMBO Rep 3:583-588
-
(2002)
EMBO Rep
, vol.3
, pp. 583-588
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
Muller, V.4
Jacobsen, H.5
Spooren, W.6
Fuss, B.7
Mallon, B.8
Macklin, W.B.9
Fujiwara, H.10
Hasegawa, M.11
Iwatsubo, T.12
Kretzschmar, H.A.13
Haass, C.14
-
72
-
-
23444442557
-
The fragile X tremor ataxia syndrome in the differential diagnosis of multiple system atrophy: Data from the EMSA Study Group
-
Kamm C, Healy DG, Quinn NP, Wullner U, Moller JC, Schols L, Geser F, Burk K, Borglum AD, Pellecchia MT, Tolosa E, del Sorbo F, Nilsson C, Bandmann O, Sharma M, Mayer P, Gasteiger M, Haworth A, Ozawa T, Lees AJ, Short J, Giunti P, Holinski-Feder E, Illig T, Wichmann HE, Wenning GK, Wood NW, Gasser T (2005) The fragile X tremor ataxia syndrome in the differential diagnosis of multiple system atrophy: data from the EMSA Study Group. Brain 128:1855-1860
-
(2005)
Brain
, vol.128
, pp. 1855-1860
-
-
Kamm, C.1
Healy, D.G.2
Quinn, N.P.3
Wullner, U.4
Moller, J.C.5
Schols, L.6
Geser, F.7
Burk, K.8
Borglum, A.D.9
Pellecchia, M.T.10
Tolosa, E.11
Del Sorbo, F.12
Nilsson, C.13
Bandmann, O.14
Sharma, M.15
Mayer, P.16
Gasteiger, M.17
Haworth, A.18
Ozawa, T.19
Lees, A.J.20
Short, J.21
Giunti, P.22
Holinski-Feder, E.23
Illig, T.24
Wichmann, H.E.25
Wenning, G.K.26
Wood, N.W.27
Gasser, T.28
more..
-
73
-
-
0025999502
-
Argyrophilic ubiquitinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (Multiple system atrophy)
-
Kato S, Nakamura H, Hirano A, Ito H, Llena JF, Yen SH (1991) Argyrophilic ubiquitinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (multiple system atrophy). Acta Neuropathol 82:488-493
-
(1991)
Acta Neuropathol
, vol.82
, pp. 488-493
-
-
Kato, S.1
Nakamura, H.2
Hirano, A.3
Ito, H.4
Llena, J.F.5
Yen, S.H.6
-
74
-
-
27744518721
-
Parkinsonism and nigrostriatal dysfunction are associated with spinocerebellar ataxia type 6 (SCA6)
-
Khan NL, Giunti P, Sweeney MG, Scherfler C, Brien MO, Piccini P, Wood NW, Lees AJ (2005) Parkinsonism and nigrostriatal dysfunction are associated with spinocerebellar ataxia type 6 (SCA6). Mov Disord 20:1115-1119
-
(2005)
Mov Disord
, vol.20
, pp. 1115-1119
-
-
Khan, N.L.1
Giunti, P.2
Sweeney, M.G.3
Scherfler, C.4
Brien, M.O.5
Piccini, P.6
Wood, N.W.7
Lees, A.J.8
-
75
-
-
84885461450
-
Alpha-synucleinopathy associated with G51D SNCA mutation: A link between Parkinson’s disease and multiple system atrophy?
-
Kiely AP, Asi YT, Kara E, Limousin P, Ling H, Lewis P, Proukakis C, Quinn N, Lees AJ, Hardy J, Revesz T, Houlden H, Holton JL (2013) Alpha-synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy? Acta Neuropathol 125:753-769
-
(2013)
Acta Neuropathol
, vol.125
, pp. 753-769
-
-
Kiely, A.P.1
Asi, Y.T.2
Kara, E.3
Limousin, P.4
Ling, H.5
Lewis, P.6
Proukakis, C.7
Quinn, N.8
Lees, A.J.9
Hardy, J.10
Revesz, T.11
Houlden, H.12
Holton, J.L.13
-
76
-
-
40849118624
-
Alpha-synuclein activates stress signaling protein kinases in THP-1 cells and microglia
-
Klegeris A, Pelech S, Giasson BI, Maguire J, Zhang H, McGeer EG, McGeer PL (2008) Alpha-synuclein activates stress signaling protein kinases in THP-1 cells and microglia. Neurobiol Aging 29:739-752
-
(2008)
Neurobiol Aging
, vol.29
, pp. 739-752
-
-
Klegeris, A.1
Pelech, S.2
Giasson, B.I.3
Maguire, J.4
Zhang, H.5
Mc Geer, E.G.6
Mc Geer, P.L.7
-
77
-
-
6844236985
-
The natural history of degenerative ataxia: A retrospective study in 466 patients
-
Klockgether T, Ludtke R, Kramer B, Abele M, Burk K, Schols L, Riess O, Laccone F, Boesch S, Lopes-Cendes I, Brice A, Inzelberg R, Zilber N, Dichgans J (1998) The natural history of degenerative ataxia: a retrospective study in 466 patients. Brain 121(Pt 4):589-600
-
(1998)
Brain
, vol.121
, pp. 589-600
-
-
Klockgether, T.1
Ludtke, R.2
Kramer, B.3
Abele, M.4
Burk, K.5
Schols, L.6
Riess, O.7
Laccone, F.8
Boesch, S.9
Lopes-Cendes, I.10
Brice, A.11
Inzelberg, R.12
Zilber, N.13
Dichgans, J.14
-
78
-
-
43249114934
-
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson’s disease
-
Kordower JH, Chu Y, Hauser RA, Freeman TB, Olanow CW (2008) Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson’s disease. Nat Med 14:504-506
-
(2008)
Nat Med
, vol.14
, pp. 504-506
-
-
Kordower, J.H.1
Chu, Y.2
Hauser, R.A.3
Freeman, T.B.4
Olanow, C.W.5
-
79
-
-
2342556414
-
Fibrillization of alpha-synuclein and tau in familial Parkinson’s disease caused by the A53T alpha-synuclein mutation
-
Kotzbauer PT, Giasson BI, Kravitz AV, Golbe LI, Mark MH, Trojanowski JQ, Lee VM (2004) Fibrillization of alpha-synuclein and tau in familial Parkinson’s disease caused by the A53T alpha-synuclein mutation. Exp Neurol 187:279-288
-
(2004)
Exp Neurol
, vol.187
, pp. 279-288
-
-
Kotzbauer, P.T.1
Giasson, B.I.2
Kravitz, A.V.3
Golbe, L.I.4
Mark, M.H.5
Trojanowski, J.Q.6
Lee, V.M.7
-
80
-
-
84956978978
-
-
Kovacs GG, Laszlo L, Kovacs J, Jensen PH, Lindersson E, Botond G, Molnar T, Perczel A, Hudecz F, Mezo G, Erdei A, Tirian L, Lehotzky A, Gelpi E, Budka H, Ovadi J (2004) Natively unfolded
-
(2004)
Natively Unfolded
-
-
Kovacs, G.G.1
Laszlo, L.2
Kovacs, J.3
Jensen, P.H.4
Lindersson, E.5
Botond, G.6
Molnar, T.7
Perczel, A.8
Hudecz, F.9
Mezo, G.10
Erdei, A.11
Tirian, L.12
Lehotzky, A.13
Gelpi, E.14
Budka, H.15
Ovadi, J.16
-
81
-
-
5144231819
-
-
Neurobiol Dis
-
tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies. Neurobiol Dis 17:155-162
-
Tubulin Polymerization Promoting Protein Tppp/P25 is a Common Marker of Alpha-Synucleinopathies
, vol.17
, pp. 155-162
-
-
Kovacs, G.G.1
Laszlo, L.2
Kovacs, J.3
Jensen, P.H.4
Lindersson, E.5
Botond, G.6
Molnar, T.7
Perczel, A.8
Hudecz, F.9
Mezo, G.10
Erdei, A.11
Tirian, L.12
Lehotzky, A.13
Gelpi, E.14
Budka, H.15
Ovadi, J.16
-
82
-
-
33846558382
-
The brain-specific protein TPPP/p25 in pathological protein deposits of neurodegenerative diseases
-
Kovacs GG, Gelpi E, Lehotzky A, Hoftberger R, Erdei A, Budka H, Ovadi J (2007) The brain-specific protein TPPP/p25 in pathological protein deposits of neurodegenerative diseases. Acta Neuropathol 113:153-161
-
(2007)
Acta Neuropathol
, vol.113
, pp. 153-161
-
-
Kovacs, G.G.1
Gelpi, E.2
Lehotzky, A.3
Hoftberger, R.4
Erdei, A.5
Budka, H.6
Ovadi, J.7
-
83
-
-
34249105775
-
Gene expression changes in postmortem tissue from the rostral pons of multiple system atrophy patients
-
Langerveld AJ, Mihalko D, Delong C, Walburn J, Ide CF (2007) Gene expression changes in postmortem tissue from the rostral pons of multiple system atrophy patients. Mov Disord 22:766-777
-
(2007)
Mov Disord
, vol.22
, pp. 766-777
-
-
Langerveld, A.J.1
Mihalko, D.2
Delong, C.3
Walburn, J.4
Ide, C.F.5
-
84
-
-
0028087201
-
Cellular pathology of multiple system atrophy: A review
-
Lantos PL, Papp MI (1994) Cellular pathology of multiple system atrophy: a review. J Neurol Neurosurg Psychiatry 57:129-133
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 129-133
-
-
Lantos, P.L.1
Papp, M.I.2
-
85
-
-
84864023667
-
Alpha-synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson’s disease
-
Lastres-Becker I, Ulusoy A, Innamorato NG, Sahin G, Rabano A, Kirik D, Cuadrado A (2012) Alpha-synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson’s disease. Hum Mol Genet 21:3173-3192
-
(2012)
Hum Mol Genet
, vol.21
, pp. 3173-3192
-
-
Lastres-Becker, I.1
Ulusoy, A.2
Innamorato, N.G.3
Sahin, G.4
Rabano, A.5
Kirik, D.6
Cuadrado, A.7
-
86
-
-
40749094842
-
Origins and effects of extracellular alpha-synuclein: Implications in Parkinson’s disease
-
Lee SJ (2008) Origins and effects of extracellular alpha-synuclein: implications in Parkinson’s disease. J Mol Neurosci 34:17-22
-
(2008)
J Mol Neurosci
, vol.34
, pp. 17-22
-
-
Lee, S.J.1
-
87
-
-
77950571596
-
Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucle-inopathies
-
Lee HJ, Suk JE, Patrick C, Bae EJ, Cho JH, Rho S, Hwang D, Masliah E, Lee SJ (2010a) Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucle-inopathies. J Biol Chem 285:9262-9272
-
(2010)
J Biol Chem
, vol.285
, pp. 9262-9272
-
-
Lee, H.J.1
Suk, J.E.2
Patrick, C.3
Bae, E.J.4
Cho, J.H.5
Rho, S.6
Hwang, D.7
Masliah, E.8
Lee, S.J.9
-
88
-
-
78649907008
-
Cell-to-cell transmission of nonprion protein aggregates
-
Lee SJ, Desplats P, Sigurdson C, Tsigelny I, Masliah E (2010b) Cell-to-cell transmission of nonprion protein aggregates. Nat Rev Neurol 6:702-706
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 702-706
-
-
Lee, S.J.1
Desplats, P.2
Sigurdson, C.3
Tsigelny, I.4
Masliah, E.5
-
89
-
-
77957260958
-
Tau protein: Relevance to Parkinson’s disease
-
Lei P, Ayton S, Finkelstein DI, Adlard PA, Masters CL, Bush AI (2010) Tau protein: relevance to Parkinson’s disease. Int J Biochem Cell Biol 42:1775-1778
-
(2010)
Int J Biochem Cell Biol
, vol.42
, pp. 1775-1778
-
-
Lei, P.1
Ayton, S.2
Finkelstein, D.I.3
Adlard, P.A.4
Masters, C.L.5
Bush, A.I.6
-
90
-
-
43249110200
-
Lewy bodies in grafted neurons in subjects with Parkinson’s disease suggest host-to-graft disease propagation
-
Li JY, Englund E, Holton JL, Soulet D, Hagell P, Lees AJ, Lashley T, Quinn NP, Rehncrona S, Bjorklund A, Widner H, Revesz T, Lindvall O, Brundin P (2008) Lewy bodies in grafted neurons in subjects with Parkinson’s disease suggest host-to-graft disease propagation. Nat Med 14:501-503
-
(2008)
Nat Med
, vol.14
, pp. 501-503
-
-
Li, J.Y.1
Englund, E.2
Holton, J.L.3
Soulet, D.4
Hagell, P.5
Lees, A.J.6
Lashley, T.7
Quinn, N.P.8
Rehncrona, S.9
Bjorklund, A.10
Widner, H.11
Revesz, T.12
Lindvall, O.13
Brundin, P.14
-
91
-
-
69549106313
-
Clinically probable multiple system atrophy with predominant parkinsonism associated with myotonic dystrophy type 2
-
Lim SY, Wadia P, Wenning GK, Lang AE (2009a) Clinically probable multiple system atrophy with predominant parkinsonism associated with myotonic dystrophy type 2. Mov Disord 24:1407-1409
-
(2009)
Mov Disord
, vol.24
, pp. 1407-1409
-
-
Lim, S.Y.1
Wadia, P.2
Wenning, G.K.3
Lang, A.E.4
-
92
-
-
70349652499
-
White matter hyperintensities in patients with multiple system atrophy
-
Lim TS, Lee PH, Kim HS, Yong SW (2009b) White matter hyperintensities in patients with multiple system atrophy. J Neurol 256:1663-1670
-
(2009)
J Neurol
, vol.256
, pp. 1663-1670
-
-
Lim, T.S.1
Lee, P.H.2
Kim, H.S.3
Yong, S.W.4
-
93
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443:787-795
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
94
-
-
34247117930
-
The SCA17 phenotype can include features of MSA-C, PSP and cognitive impairment
-
Lin IS, Wu RM, Lee-Chen GJ, Shan DE, Gwinn-Hardy K (2007) The SCA17 phenotype can include features of MSA-C, PSP and cognitive impairment. Parkinsonism Relat Disord 13:246-249
-
(2007)
Parkinsonism Relat Disord
, vol.13
, pp. 246-249
-
-
Lin, I.S.1
Wu, R.M.2
Lee-Chen, G.J.3
Shan, D.E.4
Gwinn-Hardy, K.5
-
95
-
-
34547657291
-
Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy
-
Lincoln SJ, Ross OA, Milkovic NM, Dickson DW, Rajput A, Robinson CA, Papapetropoulos S, Mash DC, Farrer MJ (2007) Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy. Parkinsonism Relat Disord 13:340-342
-
(2007)
Parkinsonism Relat Disord
, vol.13
, pp. 340-342
-
-
Lincoln, S.J.1
Ross, O.A.2
Milkovic, N.M.3
Dickson, D.W.4
Rajput, A.5
Robinson, C.A.6
Papapetropoulos, S.7
Mash, D.C.8
Farrer, M.J.9
-
96
-
-
20044383388
-
P25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies
-
Lindersson E, Lundvig D, Petersen C, Madsen P, Nyengaard JR, Hojrup P, Moos T, Otzen D, Gai WP, Blumbergs PC, Jensen PH (2005) p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies. J Biol Chem 280:5703-5715
-
(2005)
J Biol Chem
, vol.280
, pp. 5703-5715
-
-
Lindersson, E.1
Lundvig, D.2
Petersen, C.3
Madsen, P.4
Nyengaard, J.R.5
Hojrup, P.6
Moos, T.7
Otzen, D.8
Gai, W.P.9
Blumbergs, P.C.10
Jensen, P.H.11
-
97
-
-
0031683914
-
Myelin degeneration in multiple system atrophy detected by unique antibodies
-
Matsuo A, Akiguchi I, Lee GC, McGeer EG, McGeer PL, Kimura J (1998) Myelin degeneration in multiple system atrophy detected by unique antibodies. Am J Pathol 153:735-744
-
(1998)
Am J Pathol
, vol.153
, pp. 735-744
-
-
Matsuo, A.1
Akiguchi, I.2
Lee, G.C.3
Mc Geer, E.G.4
Mc Geer, P.L.5
Kimura, J.6
-
98
-
-
79955701611
-
DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
-
Mc Coy MK, Cookson MR (2011) DJ-1 regulation of mitochondrial function and autophagy through oxidative stress. Autophagy 7:531-532
-
(2011)
Autophagy
, vol.7
, pp. 531-532
-
-
Mc Coy, M.K.1
Cookson, M.R.2
-
99
-
-
27744455451
-
Absence of alpha-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia
-
Miller DW, Johnson JM, Solano SM, Hollingsworth ZR, Standaert DG, Young AB (2005) Absence of alpha-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia. J Neural Transm 112:1613-1624
-
(2005)
J Neural Transm
, vol.112
, pp. 1613-1624
-
-
Miller, D.W.1
Johnson, J.M.2
Solano, S.M.3
Hollingsworth, Z.R.4
Standaert, D.G.5
Young, A.B.6
-
101
-
-
0034719060
-
Multiple system atrophy/progressive supranuclear palsy: Alpha-synuclein, synphilin, tau, and APOE
-
Morris HR, Vaughan JR, Datta SR, Bandopadhyay R, Rohan De Silva HA, Schrag A, Cairns NJ, Burn D, Nath U, Lantos PL, Daniel S, Lees AJ, Quinn NP, Wood NW (2000) Multiple system atrophy/progressive supranuclear palsy: alpha-synuclein, synphilin, tau, and APOE. Neurology 55:1918-1920
-
(2000)
Neurology
, vol.55
, pp. 1918-1920
-
-
Morris, H.R.1
Vaughan, J.R.2
Datta, S.R.3
Bandopadhyay, R.4
Rohan De Silva, H.A.5
Schrag, A.6
Cairns, N.J.7
Burn, D.8
Nath, U.9
Lantos, P.L.10
Daniel, S.11
Lees, A.J.12
Quinn, N.P.13
Wood, N.W.14
-
102
-
-
0030610247
-
Expression of microtubule-associated proteins MAP2 and tau in cultured rat brain oligodendrocytes
-
Muller R, Heinrich M, Heck S, Blohm D, Richter-Landsberg C (1997) Expression of microtubule-associated proteins MAP2 and tau in cultured rat brain oligodendrocytes. Cell Tissue Res 288:239-249
-
(1997)
Cell Tissue Res
, vol.288
, pp. 239-249
-
-
Muller, R.1
Heinrich, M.2
Heck, S.3
Blohm, D.4
Richter-Landsberg, C.5
-
103
-
-
79957559199
-
Tau-positive glial cytoplasmic granules in multiple system atrophy
-
Nagaishi M, Yokoo H, Nakazato Y (2011) Tau-positive glial cytoplasmic granules in multiple system atrophy. Neuropathology 31:299-305
-
(2011)
Neuropathology
, vol.31
, pp. 299-305
-
-
Nagaishi, M.1
Yokoo, H.2
Nakazato, Y.3
-
104
-
-
0031842931
-
Cyclin-dependent kinase 5 and mitogen-activated protein kinase in glial cytoplasmic inclusions in multiple system atrophy
-
Nakamura S, Kawamoto Y, Nakano S, Akiguchi I, Kimura J (1998) Cyclin-dependent kinase 5 and mitogen-activated protein kinase in glial cytoplasmic inclusions in multiple system atrophy. J Neuropathol Exp Neurol 57:690-698
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 690-698
-
-
Nakamura, S.1
Kawamoto, Y.2
Nakano, S.3
Akiguchi, I.4
Kimura, J.5
-
105
-
-
0026115598
-
Environmental-occupational risk factors and familial associations in multiple system atrophy: A preliminary investigation
-
Nee LE, Gomez MR, Dambrosia J, Bale S, Eldridge R, Polinsky RJ (1991) Environmental-occupational risk factors and familial associations in multiple system atrophy: a preliminary investigation. Clin Auton Res 1:9-13
-
(1991)
Clin Auton Res
, vol.1
, pp. 9-13
-
-
Nee, L.E.1
Gomez, M.R.2
Dambrosia, J.3
Bale, S.4
Eldridge, R.5
Polinsky, R.J.6
-
106
-
-
0032740464
-
A study of five candidate genes in Parkinson’s disease and related neurodegenerative disorders. European Study Group on Atypical Parkinsonism
-
Nicholl DJ, Bennett P, Hiller L, Bonifati V, Vanacore N, Fabbrini G, Marconi R, Colosimo C, Lamberti P, Stocchi F, Bonuccelli U, Vieregge P, Ramsden DB, Meco G, Williams AC (1999) A study of five candidate genes in Parkinson’s disease and related neurodegenerative disorders. European Study Group on Atypical Parkinsonism. Neurology 53:1415-1421
-
(1999)
Neurology
, vol.53
, pp. 1415-1421
-
-
Nicholl, D.J.1
Bennett, P.2
Hiller, L.3
Bonifati, V.4
Vanacore, N.5
Fabbrini, G.6
Marconi, R.7
Colosimo, C.8
Lamberti, P.9
Stocchi, F.10
Bonuccelli, U.11
Vieregge, P.12
Ramsden, D.B.13
Meco, G.14
Williams, A.C.15
-
107
-
-
33847731846
-
Multiple system atrophy in a patient with the spinocerebellar ataxia 3 gene mutation
-
Nirenberg MJ, Libien J, Vonsattel JP, Fahn S (2007) Multiple system atrophy in a patient with the spinocerebellar ataxia 3 gene mutation. Mov Disord 22:251-254
-
(2007)
Mov Disord
, vol.22
, pp. 251-254
-
-
Nirenberg, M.J.1
Libien, J.2
Vonsattel, J.P.3
Fahn, S.4
-
108
-
-
7044226609
-
A quantitative investigation of neuronal cytoplasmic and intranuclear inclusions in the pontine and inferior olivary nuclei in multiple system atrophy
-
Nishie M, Mori F, Yoshimoto M, Takahashi H, Wakabayashi K (2004) A quantitative investigation of neuronal cytoplasmic and intranuclear inclusions in the pontine and inferior olivary nuclei in multiple system atrophy. Neuropathol Appl Neurobiol 30:546-554
-
(2004)
Neuropathol Appl Neurobiol
, vol.30
, pp. 546-554
-
-
Nishie, M.1
Mori, F.2
Yoshimoto, M.3
Takahashi, H.4
Wakabayashi, K.5
-
109
-
-
0036654040
-
Contribution of the interleukin-1beta gene polymorphism in multiple system atrophy
-
Nishimura M, Kawakami H, Komure O, Maruyama H, Morino H, Izumi Y, Nakamura S, Kaji R, Kuno S (2002) Contribution of the interleukin-1beta gene polymorphism in multiple system atrophy. Mov Disord 17:808-811
-
(2002)
Mov Disord
, vol.17
, pp. 808-811
-
-
Nishimura, M.1
Kawakami, H.2
Komure, O.3
Maruyama, H.4
Morino, H.5
Izumi, Y.6
Nakamura, S.7
Kaji, R.8
Kuno, S.9
-
110
-
-
26444434944
-
Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer’s disease, Parkinson’s disease, and multiple system atrophy
-
Nishimura M, Kuno S, Kaji R, Kawakami H (2005a) Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer’s disease, Parkinson’s disease, and multiple system atrophy. Mov Disord 20:1031-1033
-
(2005)
Mov Disord
, vol.20
, pp. 1031-1033
-
-
Nishimura, M.1
Kuno, S.2
Kaji, R.3
Kawakami, H.4
-
111
-
-
12344255081
-
Influence of a tumor necrosis factor gene polymorphism in Japanese patients with multiple system atrophy
-
Nishimura M, Kuno S, Kaji R, Kawakami H (2005b) Influence of a tumor necrosis factor gene polymorphism in Japanese patients with multiple system atrophy. Neurosci Lett 374:218-221
-
(2005)
Neurosci Lett
, vol.374
, pp. 218-221
-
-
Nishimura, M.1
Kuno, S.2
Kaji, R.3
Kawakami, H.4
-
112
-
-
10244264868
-
TPPP/p25: From unfolded protein to misfolding disease: Prediction and experiments
-
Orosz F, Kovacs GG, Lehotzky A, Olah J, Vincze O, Ovadi J (2004) TPPP/p25: from unfolded protein to misfolding disease: prediction and experiments. Biol Cell 96:701-711
-
(2004)
Biol Cell
, vol.96
, pp. 701-711
-
-
Orosz, F.1
Kovacs, G.G.2
Lehotzky, A.3
Olah, J.4
Vincze, O.5
Ovadi, J.6
-
113
-
-
22444431956
-
Jensen PH (2005) p25alpha is flexible but natively folded and binds tubulin with oligomeric stoichiometry
-
Otzen DE, Lundvig DM, Wimmer R, Nielsen LH, Pedersen JR, Jensen PH (2005) p25alpha is flexible but natively folded and binds tubulin with oligomeric stoichiometry. Protein Sci 14:1396-1409
-
Protein Sci
, vol.14
, pp. 1396-1409
-
-
Otzen, D.E.1
Lundvig, D.M.2
Wimmer, R.3
Nielsen, L.H.4
Pedersen, J.R.5
-
114
-
-
77955366745
-
Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: Implications for Parkinson’s disease pathogenesis and therapies
-
Oueslati A, Fournier M, Lashuel HA (2010) Role of post-translational modifications in modulating the structure, function and toxicity of alpha-synuclein: implications for Parkinson’s disease pathogenesis and therapies. Prog Brain Res 183:115-145
-
(2010)
Prog Brain Res
, vol.183
, pp. 115-145
-
-
Oueslati, A.1
Fournier, M.2
Lashuel, H.A.3
-
115
-
-
67650175319
-
An unstructured protein with destructive potential: TPPP/p25 in neurodegeneration
-
Ovadi J, Orosz F (2009) An unstructured protein with destructive potential: TPPP/p25 in neurodegeneration. Bioessays 31:676-686
-
(2009)
Bioessays
, vol.31
, pp. 676-686
-
-
Ovadi, J.1
Orosz, F.2
-
116
-
-
0033618481
-
No mutation in the entire coding region of the alpha-synuclein gene in pathologically confirmed cases of multiple system atrophy
-
Ozawa T, Takano H, Onodera O, Kobayashi H, Ikeuchi T, Koide R, Okuizumi K, Shimohata T, Wakabayashi K, Takahashi H, Tsuji S (1999) No mutation in the entire coding region of the alpha-synuclein gene in pathologically confirmed cases of multiple system atrophy. Neurosci Lett 270:110-112
-
(1999)
Neurosci Lett
, vol.270
, pp. 110-112
-
-
Ozawa, T.1
Takano, H.2
Onodera, O.3
Kobayashi, H.4
Ikeuchi, T.5
Koide, R.6
Okuizumi, K.7
Shimohata, T.8
Wakabayashi, K.9
Takahashi, H.10
Tsuji, S.11
-
117
-
-
0034890258
-
Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy
-
Ozawa T, Okuizumi K, Ikeuchi T, Wakabayashi K, Takahashi H, Tsuji S (2001a) Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy. Acta Neuropathol 102:188-190
-
(2001)
Acta Neuropathol
, vol.102
, pp. 188-190
-
-
Ozawa, T.1
Okuizumi, K.2
Ikeuchi, T.3
Wakabayashi, K.4
Takahashi, H.5
Tsuji, S.6
-
118
-
-
0034890258
-
Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy
-
Ozawa T, Okuizumi K, Ikeuchi T, Wakabayashi K, Takahashi H, Tsuji S (2001b) Analysis of the expression level of alpha-synuclein mRNA using postmortem brain samples from pathologically confirmed cases of multiple system atrophy. Acta Neuropathol (Berl) 102:188-190
-
(2001)
Acta Neuropathol (Berl)
, vol.102
, pp. 188-190
-
-
Ozawa, T.1
Okuizumi, K.2
Ikeuchi, T.3
Wakabayashi, K.4
Takahashi, H.5
Tsuji, S.6
-
119
-
-
10344260246
-
The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: Clinicopathological correlations
-
Ozawa T, Paviour D, Quinn NP, Josephs KA, Sangha H, Kilford L, Healy DG, Wood NW, Lees AJ, Holton JL, Revesz T (2004) The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. Brain 127:2657-2671
-
(2004)
Brain
, vol.127
, pp. 2657-2671
-
-
Ozawa, T.1
Paviour, D.2
Quinn, N.P.3
Josephs, K.A.4
Sangha, H.5
Kilford, L.6
Healy, D.G.7
Wood, N.W.8
Lees, A.J.9
Holton, J.L.10
Revesz, T.11
-
120
-
-
33645557958
-
The alpha-synuclein gene in multiple system atrophy
-
Ozawa T, Healy DG, Abou-Sleiman PM, Ahmadi KR, Quinn N, Lees AJ, Shaw K, Wullner U, Berciano J, Moller JC, Kamm C, Burk K, Josephs KA, Barone P, Tolosa E, Goldstein DB, Wenning G, Geser F, Holton JL, Gasser T, Revesz T, Wood NW (2006) The alpha-synuclein gene in multiple system atrophy. J Neurol Neurosurg Psychiatry 77:464-467
-
(2006)
J Neurol Neurosurg Psychiatry
, vol.77
, pp. 464-467
-
-
Ozawa, T.1
Healy, D.G.2
Abou-Sleiman, P.M.3
Ahmadi, K.R.4
Quinn, N.5
Lees, A.J.6
Shaw, K.7
Wullner, U.8
Berciano, J.9
Moller, J.C.10
Kamm, C.11
Burk, K.12
Josephs, K.A.13
Barone, P.14
Tolosa, E.15
Goldstein, D.B.16
Wenning, G.17
Geser, F.18
Holton, J.L.19
Gasser, T.20
Revesz, T.21
Wood, N.W.22
more..
-
121
-
-
34247276516
-
G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy
-
Ozelius LJ, Foroud T, May S, Senthil G, Sandroni P, Low PA, Reich S, Colcher A, Stern MB, Ondo WG, Jankovic J, Huang N, Tanner CM, Novak P, Gilman S, Marshall FJ, Wooten GF, Chelimsky TC, Shults CW (2007) G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy. Mov Disord 22:546-549
-
(2007)
Mov Disord
, vol.22
, pp. 546-549
-
-
Ozelius, L.J.1
Foroud, T.2
May, S.3
Senthil, G.4
Sandroni, P.5
Low, P.A.6
Reich, S.7
Colcher, A.8
Stern, M.B.9
Ondo, W.G.10
Jankovic, J.11
Huang, N.12
Tanner, C.M.13
Novak, P.14
Gilman, S.15
Marshall, F.J.16
Wooten, G.F.17
Chelimsky, T.C.18
Shults, C.W.19
-
122
-
-
42449095464
-
Mitochondrial association of alpha-synuclein causes oxidative stress
-
Parihar MS, Parihar A, Fujita M, Hashimoto M, Ghafourifar P (2008) Mitochondrial association of alpha-synuclein causes oxidative stress. Cell Mol Life Sci 65:1272-1284
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1272-1284
-
-
Parihar, M.S.1
Parihar, A.2
Fujita, M.3
Hashimoto, M.4
Ghafourifar, P.5
-
123
-
-
0029065450
-
CYP2D6-debrisoquine hydroxylase gene polymorphism in multiple system atrophy
-
Plante-Bordeneuve V, Bandmann O, Wenning G, Quinn NP, Daniel SE, Harding AE (1995) CYP2D6-debrisoquine hydroxylase gene polymorphism in multiple system atrophy. Mov Disord 10:277-278
-
(1995)
Mov Disord
, vol.10
, pp. 277-278
-
-
Plante-Bordeneuve, V.1
Bandmann, O.2
Wenning, G.3
Quinn, N.P.4
Daniel, S.E.5
Harding, A.E.6
-
124
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, di Iorio G, Golbe LI, Nussbaum RL (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease. Science 276:2045-2047
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
125
-
-
43449090378
-
Nitrated alpha-synuclein and microglial neuroregulatory activities
-
Reynolds AD, Kadiu I, Garg SK, Glanzer JG, Nordgren T, Ciborowski P, Banerjee R, Gendelman HE (2008) Nitrated alpha-synuclein and microglial neuroregulatory activities. J Neuroimmune Pharmacol 3:59-74
-
(2008)
J Neuroimmune Pharmacol
, vol.3
, pp. 59-74
-
-
Reynolds, A.D.1
Kadiu, I.2
Garg, S.K.3
Glanzer, J.G.4
Nordgren, T.5
Ciborowski, P.6
Banerjee, R.7
Gendelman, H.E.8
-
126
-
-
74149088878
-
Alpha-synuclein promotes the recruitment of tau to protein inclusions in oligodendroglial cells: Effects of oxidative and proteolytic stress
-
Riedel M, Goldbaum O, Richter-Landsberg C (2009) Alpha-synuclein promotes the recruitment of tau to protein inclusions in oligodendroglial cells: effects of oxidative and proteolytic stress. J Mol Neurosci 39:226-234
-
(2009)
J Mol Neurosci
, vol.39
, pp. 226-234
-
-
Riedel, M.1
Goldbaum, O.2
Richter-Landsberg, C.3
-
127
-
-
77749339881
-
Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson’s disease
-
Rojo AI, Innamorato NG, Martin-Moreno AM, de Ceballos ML, Yamamoto M, Cuadrado A (2010) Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson’s disease. Glia 58:588-598
-
(2010)
Glia
, vol.58
, pp. 588-598
-
-
Rojo, A.I.1
Innamorato, N.G.2
Martin-Moreno, A.M.3
De Ceballos, M.L.4
Yamamoto, M.5
Cuadrado, A.6
-
128
-
-
32044466285
-
Lrrk2 and Lewy body disease
-
Ross OA, Toft M, Whittle AJ, Johnson JL, Papapetropoulos S, Mash DC, Litvan I, Gordon MF, Wszolek ZK, Farrer MJ, Dickson DW (2006) Lrrk2 and Lewy body disease. Ann Neurol 59:388-393
-
(2006)
Ann Neurol
, vol.59
, pp. 388-393
-
-
Ross, O.A.1
Toft, M.2
Whittle, A.J.3
Johnson, J.L.4
Papapetropoulos, S.5
Mash, D.C.6
Litvan, I.7
Gordon, M.F.8
Wszolek, Z.K.9
Farrer, M.J.10
Dickson, D.W.11
-
129
-
-
77950532431
-
Reply to: SNCA variants are associated with increased risk of multiple system atrophy
-
Ross OA, Vilarino-Güell C, Wszolek ZK, Farrer MJ, Dickson DW (2009) Reply to: SNCA variants are associated with increased risk of multiple system atrophy. Ann Neurol 67:414-415
-
(2009)
Ann Neurol
, vol.67
, pp. 414-415
-
-
Ross, O.A.1
Vilarino-Güell, C.2
Wszolek, Z.K.3
Farrer, M.J.4
Dickson, D.W.5
-
130
-
-
84888873725
-
First genome-wide association study in multiple system atrophy [abstract]
-
Sailer A, Consortium, O. B. O. T. M. G. (2012) First genome-wide association study in multiple system atrophy [abstract]. Mov Disord 27:1425
-
(2012)
Mov Disord
, vol.27
, pp. 1425
-
-
Sailer, A.1
Consortium, O.B.2
-
131
-
-
79958118184
-
Copy number loss of (Src homology 2 domain containing)-transforming protein 2 (SHC2) gene: Discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy
-
Sasaki H, Emi M, Iijima H, Ito N, Sato H, Yabe I, Kato T, Utsumi J, Matsubara K (2011) Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy. Mol Brain 4:24
-
(2011)
Mol Brain
, vol.4
, pp. 24
-
-
Sasaki, H.1
Emi, M.2
Iijima, H.3
Ito, N.4
Sato, H.5
Yabe, I.6
Kato, T.7
Utsumi, J.8
Matsubara, K.9
-
132
-
-
33845216661
-
The ADH1C stop mutation in multiple system atrophy patients and healthy probands in the United Kingdom and Germany
-
Schmitt I, Wullner U, Healy DG, Wood NW, Kolsch H, Heun R (2006) The ADH1C stop mutation in multiple system atrophy patients and healthy probands in the United Kingdom and Germany. Mov Disord 21:2034
-
(2006)
Mov Disord
, vol.21
, pp. 2034
-
-
Schmitt, I.1
Wullner, U.2
Healy, D.G.3
Wood, N.W.4
Kolsch, H.5
Heun, R.6
-
133
-
-
67249139655
-
SNCA variants are associated with increased risk for multiple system atrophy
-
Scholz SW, Houlden H, Schulte C, Sharma M, Li A, Berg D, Melchers A, Paudel R, Gibbs JR, Simon-Sanchez J, Paisan-Ruiz C, Bras J, Ding J, Chen H, Traynor BJ, Arepalli S, Zonozi RR, Revesz T, Holton J, Wood N, Lees A, Oertel W, Wullner U, Goldwurm S, Pellecchia MT, Illig T, Riess O, Fernandez HH, Rodriguez RL, Okun MS, Poewe W, Wenning GK, Hardy JA, Singleton AB, Gasser T, del Sorbo F, Schneider S, Bhatia KP (2009) SNCA variants are associated with increased risk for multiple system atrophy. Ann Neurol 65:610-614
-
(2009)
Ann Neurol
, vol.65
, pp. 610-614
-
-
Scholz, S.W.1
Houlden, H.2
Schulte, C.3
Sharma, M.4
Li, A.5
Berg, D.6
Melchers, A.7
Paudel, R.8
Gibbs, J.R.9
Simon-Sanchez, J.10
Paisan-Ruiz, C.11
Bras, J.12
Ding, J.13
Chen, H.14
Traynor, B.J.15
Arepalli, S.16
Zonozi, R.R.17
Revesz, T.18
Holton, J.19
Wood, N.20
Lees, A.21
Oertel, W.22
Wullner, U.23
Goldwurm, S.24
Pellecchia, M.T.25
Illig, T.26
Riess, O.27
Fernandez, H.H.28
Rodriguez, R.L.29
Okun, M.S.30
Poewe, W.31
Wenning, G.K.32
Hardy, J.A.33
Singleton, A.B.34
Gasser, T.35
Del Sorbo, F.36
Schneider, S.37
Bhatia, K.P.38
more..
-
134
-
-
65249115797
-
Glucocerebrosidase mutations in 108 neuropathologically confirmed cases of multiple system atrophy
-
Segarane B, Li A, Paudel R, Scholz S, Neumann J, Lees A, Revesz T, Hardy J, Mathias CJ, Wood NW, Holton J, Houlden H (2009) Glucocerebrosidase mutations in 108 neuropathologically confirmed cases of multiple system atrophy. Neurology 72:1185-1186
-
(2009)
Neurology
, vol.72
, pp. 1185-1186
-
-
Segarane, B.1
Li, A.2
Paudel, R.3
Scholz, S.4
Neumann, J.5
Lees, A.6
Revesz, T.7
Hardy, J.8
Mathias, C.J.9
Wood, N.W.10
Holton, J.11
Houlden, H.12
-
135
-
-
33744971602
-
Atypical protein kinase C in neurodegenerative disease II: PKCiota/lambda in tauopathies and alpha-synucleinopathies
-
Shao CY, Crary JF, Rao C, Sacktor TC, Mirra SS (2006) Atypical protein kinase C in neurodegenerative disease II: PKCiota/lambda in tauopathies and alpha-synucleinopathies. J Neuropathol Exp Neurol 65:327-335
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 327-335
-
-
Shao, C.Y.1
Crary, J.F.2
Rao, C.3
Sacktor, T.C.4
Mirra, S.S.5
-
136
-
-
43149120875
-
PRNP M129V homozygosity in multiple system atrophy vs. Parkinson’s disease
-
Shibao C, Garland EM, Gamboa A, Vnencak-Jones CL, van Woeltz M, Haines JL, Yu C, Biaggioni I (2008) PRNP M129V homozygosity in multiple system atrophy vs. Parkinson’s disease. Clin Auton Res 18:13-19
-
(2008)
Clin Auton Res
, vol.18
, pp. 13-19
-
-
Shibao, C.1
Garland, E.M.2
Gamboa, A.3
Vnencak-Jones, C.L.4
Van Woeltz, M.5
Haines, J.L.6
Yu, C.7
Biaggioni, I.8
-
137
-
-
27944436033
-
Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: Implications for multiple system atrophy
-
Shults CW, Rockenstein E, Crews L, Adame A, Mante M, Larrea G, Hashimoto M, Song D, Iwatsubo T, Tsuboi K, Masliah E (2005) Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. J Neurosci 25:10689-10699
-
(2005)
J Neurosci
, vol.25
, pp. 10689-10699
-
-
Shults, C.W.1
Rockenstein, E.2
Crews, L.3
Adame, A.4
Mante, M.5
Larrea, G.6
Hashimoto, M.7
Song, D.8
Iwatsubo, T.9
Tsuboi, K.10
Masliah, E.11
-
138
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson’s disease
-
Epub 2009 Nov 15
-
Simon-Sanchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, Paisan-Ruiz C, Lichtner P, Scholz SW, Hernandez DG, Kruger R, Federoff M, Klein C, Goate A, Perlmutter J, Bonin M, Nalls MA, Illig T, Gieger C, Houlden H, Steffens M, Okun MS, Racette BA, Cookson MR, Foote KD, Fernandez HH, Traynor BJ, Schreiber S, Arepalli S, Zonozi R, Gwinn K, van der Brug M, Lopez G, Chanock SJ, Schatzkin A, Park Y, Hollenbeck A, Gao J, Huang X, Wood NW, Lorenz D, Deuschl G, Chen H, Riess O, Hardy JA, Singleton AB, Gasser T (2009) Genome-wide association study reveals genetic risk underlying Parkinson’s disease. Nat Genet 41:1308-1312. Epub 2009 Nov 15
-
(2009)
Nat Genet
, vol.41
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.M.3
Sharma, M.4
Gibbs, J.R.5
Berg, D.6
Paisan-Ruiz, C.7
Lichtner, P.8
Scholz, S.W.9
Hernandez, D.G.10
Kruger, R.11
Federoff, M.12
Klein, C.13
Goate, A.14
Perlmutter, J.15
Bonin, M.16
Nalls, M.A.17
Illig, T.18
Gieger, C.19
Houlden, H.20
Steffens, M.21
Okun, M.S.22
Racette, B.A.23
Cookson, M.R.24
Foote, K.D.25
Fernandez, H.H.26
Traynor, B.J.27
Schreiber, S.28
Arepalli, S.29
Zonozi, R.30
Gwinn, K.31
Van Der Brug, M.32
Lopez, G.33
Chanock, S.J.34
Schatzkin, A.35
Park, Y.36
Hollenbeck, A.37
Gao, J.38
Huang, X.39
Wood, N.W.40
Lorenz, D.41
Deuschl, G.42
Chen, H.43
Riess, O.44
Hardy, J.A.45
Singleton, A.B.46
Gasser, T.47
more..
-
139
-
-
0242300619
-
Alpha-synuclein locus triplication causes Parkinson’s disease
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, Hulihan M, Peuralinna T, Dutra A, Nussbaum R, Lincoln S, Crawley A, Hanson M, Maraganore D, Adler C, Cookson MR, Muenter M, Baptista M, Miller D, Blancato J, Hardy J, Gwinn-Hardy K (2003) Alpha-synuclein locus triplication causes Parkinson’s disease. Science 302:841
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
140
-
-
29144435092
-
Heredity in multiple system atrophy
-
Soma H, Yabe I, Takei A, Fujiki N, Yanagihara T, Sasaki H (2006) Heredity in multiple system atrophy. J Neurol Sci 240:107-110
-
(2006)
J Neurol Sci
, vol.240
, pp. 107-110
-
-
Soma, H.1
Yabe, I.2
Takei, A.3
Fujiki, N.4
Yanagihara, T.5
Sasaki, H.6
-
141
-
-
52649084153
-
Associations between multiple system atrophy and polymorphisms of SLC1A4, SQSTM1, and EIF4EBP1 genes
-
Soma H, Yabe I, Takei A, Fujiki N, Yanagihara T, Sasaki H (2008) Associations between multiple system atrophy and polymorphisms of SLC1A4, SQSTM1, and EIF4EBP1 genes. Mov Disord 23:1161-1167
-
(2008)
Mov Disord
, vol.23
, pp. 1161-1167
-
-
Soma, H.1
Yabe, I.2
Takei, A.3
Fujiki, N.4
Yanagihara, T.5
Sasaki, H.6
-
142
-
-
35348909482
-
Jensen PH (2007) p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy
-
Song YJ, Lundvig DM, Huang Y, Gai WP, Blumbergs PC, Hojrup P, Otzen D, Halliday GM, Jensen PH (2007) p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy. Am J Pathol 171:1291-1303
-
Am J Pathol
, vol.171
, pp. 1291-1303
-
-
Song, Y.J.1
Lundvig, D.M.2
Huang, Y.3
Gai, W.P.4
Blumbergs, P.C.5
Hojrup, P.6
Otzen, D.7
Halliday, G.M.8
-
143
-
-
0032584686
-
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson’s disease and dementia with Lewy bodies
-
Spillantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, Goedert M (1998) Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson’s disease and dementia with Lewy bodies. Neurosci Lett 251:205-208
-
(1998)
Neurosci Lett
, vol.251
, pp. 205-208
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Cairns, N.J.4
Lantos, P.L.5
Goedert, M.6
-
144
-
-
0035449454
-
Glial cell death induced by overexpression of alpha-synuclein
-
Stefanova N, Klimaschewski L, Poewe W, Wenning GK, Reindl M (2001) Glial cell death induced by overexpression of alpha-synuclein. J Neurosci Res 65:432-438
-
(2001)
J Neurosci Res
, vol.65
, pp. 432-438
-
-
Stefanova, N.1
Klimaschewski, L.2
Poewe, W.3
Wenning, G.K.4
Reindl, M.5
-
145
-
-
14644417871
-
Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy
-
Stefanova N, Reindl M, Neumann M, Haass C, Poewe W, Kahle PJ, Wenning GK (2005a) Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy. Am J Pathol 166:869-876
-
(2005)
Am J Pathol
, vol.166
, pp. 869-876
-
-
Stefanova, N.1
Reindl, M.2
Neumann, M.3
Haass, C.4
Poewe, W.5
Kahle, P.J.6
Wenning, G.K.7
-
147
-
-
23944510851
-
Animal models of multiple system atrophy
-
Stefanova N, Tison F, Reindl M, Poewe W, Wenning GK (2005c) Animal models of multiple system atrophy. Trends Neurosci 28:501-506
-
(2005)
Trends Neurosci
, vol.28
, pp. 501-506
-
-
Stefanova, N.1
Tison, F.2
Reindl, M.3
Poewe, W.4
Wenning, G.K.5
-
148
-
-
36949032824
-
Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy: Implications for multiple system atrophy
-
Stefanova N, Reindl M, Neumann M, Kahle PJ, Poewe W, Wenning GK (2007) Microglial activation mediates neurodegeneration related to oligodendroglial alpha-synucleinopathy: implications for multiple system atrophy. Mov Disord 22:2196-2203
-
(2007)
Mov Disord
, vol.22
, pp. 2196-2203
-
-
Stefanova, N.1
Reindl, M.2
Neumann, M.3
Kahle, P.J.4
Poewe, W.5
Wenning, G.K.6
-
150
-
-
84862762387
-
Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: Implications for multiple system atrophy
-
Stefanova N, Kaufmann WA, Humpel C, Poewe W, Wenning GK (2012) Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy. Acta Neuropathol 124:51-65
-
(2012)
Acta Neuropathol
, vol.124
, pp. 51-65
-
-
Stefanova, N.1
Kaufmann, W.A.2
Humpel, C.3
Poewe, W.4
Wenning, G.K.5
-
153
-
-
51449099473
-
Synuclein activates microglia in a model of Parkinson’s disease
-
Su X, Maguire-Zeiss KA, Giuliano R, Prifti L, Venkatesh K, Federoff HJ (2008) Synuclein activates microglia in a model of Parkinson’s disease. Neurobiol Aging 29:1690-1701
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1690-1701
-
-
Su, X.1
Maguire-Zeiss, K.A.2
Giuliano, R.3
Prifti, L.4
Venkatesh, K.5
Federoff, H.J.6
-
154
-
-
70349917814
-
Mutant alpha-synuclein overexpression mediates early proinflammatory activity
-
Su X, Federoff HJ, Maguire-Zeiss KA (2009) Mutant alpha-synuclein overexpression mediates early proinflammatory activity. Neurotox Res 16:238-254
-
(2009)
Neurotox Res
, vol.16
, pp. 238-254
-
-
Su, X.1
Federoff, H.J.2
Maguire-Zeiss, K.A.3
-
155
-
-
0025769484
-
A novel brain-specific 25 kDa protein (P25) is phosphorylated by a Ser/Thr-Pro kinase (TPK II) from tau protein kinase fractions
-
Takahashi M, Tomizawa K, Ishiguro K, Sato K, Omori A, Sato S, Shiratsuchi A, Uchida T, Imahori K (1991) A novel brain-specific 25 kDa protein (p25) is phosphorylated by a Ser/Thr-Pro kinase (TPK II) from tau protein kinase fractions. FEBS Lett 289:37-43
-
(1991)
FEBS Lett
, vol.289
, pp. 37-43
-
-
Takahashi, M.1
Tomizawa, K.2
Ishiguro, K.3
Sato, K.4
Omori, A.5
Sato, S.6
Shiratsuchi, A.7
Uchida, T.8
Imahori, K.9
-
156
-
-
0030611366
-
Tau immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy
-
Takeda A, Arai N, Komori T, Iseki E, Kato S, Oda M (1997) Tau immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy. Neurosci Lett 234:63-66
-
(1997)
Neurosci Lett
, vol.234
, pp. 63-66
-
-
Takeda, A.1
Arai, N.2
Komori, T.3
Iseki, E.4
Kato, S.5
Oda, M.6
-
157
-
-
0028904035
-
Ubiquitinated alpha B-crystallin in glial cytoplasmic inclusions from the brain of a patient with multiple system atrophy
-
Tamaoka A, Mizusawa H, Mori H, Shoji S (1995) Ubiquitinated alpha B-crystallin in glial cytoplasmic inclusions from the brain of a patient with multiple system atrophy. J Neurol Sci 129:192-198
-
(1995)
J Neurol Sci
, vol.129
, pp. 192-198
-
-
Tamaoka, A.1
Mizusawa, H.2
Mori, H.3
Shoji, S.4
-
158
-
-
33746870719
-
Analysis of 14 LRRK2 mutations in Parkinson’s plus syndromes and late-onset Parkinson’s disease
-
Tan EK, Skipper L, Chua E, Wong MC, Pavanni R, Bonnard C, Kolatkar P, Liu JJ (2006) Analysis of 14 LRRK2 mutations in Parkinson’s plus syndromes and late-onset Parkinson’s disease. Mov Disord 21:997-1001
-
(2006)
Mov Disord
, vol.21
, pp. 997-1001
-
-
Tan, E.K.1
Skipper, L.2
Chua, E.3
Wong, M.C.4
Pavanni, R.5
Bonnard, C.6
Kolatkar, P.7
Liu, J.J.8
-
160
-
-
0033142961
-
Review: Tau protein pathology in Alzheimer’s disease and related disorders
-
Tolnay M, Probst A (1999) Review: Tau protein pathology in Alzheimer’s disease and related disorders. Neuropathol Appl Neurobiol 25:171-187
-
(1999)
Neuropathol Appl Neurobiol
, vol.25
, pp. 171-187
-
-
Tolnay, M.1
Probst, A.2
-
161
-
-
74249111692
-
Brain alpha-synuclein accumulation in multiple system atrophy, Parkinson’s disease and progressive supranuclear palsy: A comparative investigation
-
Tong J, Wong H, Guttman M, Ang LC, Forno LS, Shimadzu M, Rajput AH, Muenter MD, Kish SJ, Hornykiewicz O, Furukawa Y (2010) Brain alpha-synuclein accumulation in multiple system atrophy, Parkinson’s disease and progressive supranuclear palsy: a comparative investigation. Brain 133:172-188
-
(2010)
Brain
, vol.133
, pp. 172-188
-
-
Tong, J.1
Wong, H.2
Guttman, M.3
Ang, L.C.4
Forno, L.S.5
Shimadzu, M.6
Rajput, A.H.7
Muenter, M.D.8
Kish, S.J.9
Hornykiewicz, O.10
Furukawa, Y.11
-
162
-
-
35948994645
-
Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy
-
Trojanowski JQ, Revesz T (2007) Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy. Neuropathol Appl Neurobiol 33:615-620
-
(2007)
Neuropathol Appl Neurobiol
, vol.33
, pp. 615-620
-
-
Trojanowski, J.Q.1
Revesz, T.2
-
163
-
-
19444388207
-
Alpha-synuclein overexpression in oligodendrocytic cells results in impaired adhesion to fibronectin and cell death
-
Tsuboi K, Grzesiak JJ, Bouvet M, Hashimoto M, Masliah E, Shults CW (2005) Alpha-synuclein overexpression in oligodendrocytic cells results in impaired adhesion to fibronectin and cell death. Mol Cell Neurosci 29:259-268
-
(2005)
Mol Cell Neurosci
, vol.29
, pp. 259-268
-
-
Tsuboi, K.1
Grzesiak, J.J.2
Bouvet, M.3
Hashimoto, M.4
Masliah, E.5
Shults, C.W.6
-
164
-
-
0031713491
-
Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein
-
Tu PH, Galvin JE, Baba M, Giasson B, Tomita T, Leight S, Nakajo S, Iwatsubo T, Trojanowski JQ, Lee VM (1998) Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein. Ann Neurol 44:415-422
-
(1998)
Ann Neurol
, vol.44
, pp. 415-422
-
-
Tu, P.H.1
Galvin, J.E.2
Baba, M.3
Giasson, B.4
Tomita, T.5
Leight, S.6
Nakajo, S.7
Iwatsubo, T.8
Trojanowski, J.Q.9
Lee, V.M.10
-
165
-
-
70449478417
-
Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy
-
Ubhi K, Lee PH, Adame A, Inglis C, Mante M, Rockenstein E, Stefanova N, Wenning GK, Masliah E (2009) Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. J Neurosci Res 87:2728-2739
-
(2009)
J Neurosci Res
, vol.87
, pp. 2728-2739
-
-
Ubhi, K.1
Lee, P.H.2
Adame, A.3
Inglis, C.4
Mante, M.5
Rockenstein, E.6
Stefanova, N.7
Wenning, G.K.8
Masliah, E.9
-
166
-
-
77954941829
-
Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy
-
Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, Masliah E (2010a) Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy. Neuroreport 21:457-462
-
(2010)
Neuroreport
, vol.21
, pp. 457-462
-
-
Ubhi, K.1
Rockenstein, E.2
Mante, M.3
Inglis, C.4
Adame, A.5
Patrick, C.6
Masliah, E.7
-
167
-
-
77958553537
-
Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors
-
Ubhi K, Rockenstein E, Mante M, Inglis C, Adame A, Patrick C, Whitney K, Masliah E (2010b) Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors. J Neurosci 30:6236-6246
-
(2010)
J Neurosci
, vol.30
, pp. 6236-6246
-
-
Ubhi, K.1
Rockenstein, E.2
Mante, M.3
Inglis, C.4
Adame, A.5
Patrick, C.6
Whitney, K.7
Masliah, E.8
-
168
-
-
82455205801
-
Multiple system atrophy: A clinical and neuropathological perspective
-
Ubhi K, Low P, Masliah E (2011) Multiple system atrophy: a clinical and neuropathological perspective. Trends Neurosci 34:581-590
-
(2011)
Trends Neurosci
, vol.34
, pp. 581-590
-
-
Ubhi, K.1
Low, P.2
Masliah, E.3
-
169
-
-
20144367968
-
Case-control study of multiple system atrophy
-
Vanacore N, Bonifati V, Fabbrini G, Colosimo C, de Michele G, Marconi R, Stocchi F, Nicholl D, Bonuccelli U, de Mari M, Vieregge P, Meco G (2005) Case-control study of multiple system atrophy. Mov Disord 20:158-163
-
(2005)
Mov Disord
, vol.20
, pp. 158-163
-
-
Vanacore, N.1
Bonifati, V.2
Fabbrini, G.3
Colosimo, C.4
De Michele, G.5
Marconi, R.6
Stocchi, F.7
Nicholl, D.8
Bonuccelli, U.9
De Mari, M.10
Vieregge, P.11
Meco, G.12
-
170
-
-
77955922489
-
Familial aggregation in atypical Parkinson’s disease: A case control study in multiple system atrophy and progressive supranuclear palsy
-
Vidal JS, Vidailhet M, Derkinderen P, Tzourio C, Alperovitch A (2010) Familial aggregation in atypical Parkinson’s disease: a case control study in multiple system atrophy and progressive supranuclear palsy. J Neurol 257:1388-1393
-
(2010)
J Neurol
, vol.257
, pp. 1388-1393
-
-
Vidal, J.S.1
Vidailhet, M.2
Derkinderen, P.3
Tzourio, C.4
Alperovitch, A.5
-
171
-
-
33745268155
-
Transcriptional changes in multiple system atrophy and Parkinson’s disease putamen
-
Vogt IR, Lees AJ, Evert BO, Klockgether T, Bonin M, Wullner U (2006) Transcriptional changes in multiple system atrophy and Parkinson’s disease putamen. Exp Neurol 199:465-478
-
(2006)
Exp Neurol
, vol.199
, pp. 465-478
-
-
Vogt, I.R.1
Lees, A.J.2
Evert, B.O.3
Klockgether, T.4
Bonin, M.5
Wullner, U.6
-
172
-
-
33746108503
-
Cellular pathology in multiple system atrophy
-
Wakabayashi K, Takahashi H (2006) Cellular pathology in multiple system atrophy. Neuropathology 26:338-345
-
(2006)
Neuropathology
, vol.26
, pp. 338-345
-
-
Wakabayashi, K.1
Takahashi, H.2
-
173
-
-
0032539785
-
Multiple system atrophy with severe involvement of the motor cortical areas and cerebral white matter
-
Wakabayashi K, Ikeuchi T, Ishikawa A, Takahashi H (1998) Multiple system atrophy with severe involvement of the motor cortical areas and cerebral white matter. J Neurol Sci 156:114-117
-
(1998)
J Neurol Sci
, vol.156
, pp. 114-117
-
-
Wakabayashi, K.1
Ikeuchi, T.2
Ishikawa, A.3
Takahashi, H.4
-
174
-
-
24344475263
-
An autopsy case of early (“minimal change”) olivopontocerebellar atrophy (multiple system atrophy-cerebellar)
-
Wakabayashi K, Mori F, Nishie M, Oyama Y, Kurihara A, Yoshimoto M, Kuroda N (2005) An autopsy case of early (“minimal change”) olivopontocerebellar atrophy (multiple system atrophy-cerebellar). Acta Neuropathol 110:185-190
-
(2005)
Acta Neuropathol
, vol.110
, pp. 185-190
-
-
Wakabayashi, K.1
Mori, F.2
Nishie, M.3
Oyama, Y.4
Kurihara, A.5
Yoshimoto, M.6
Kuroda, N.7
-
177
-
-
0028218344
-
Minimal change
-
Mov Disord
-
Wenning GK, Quinn N, Magalhaes M, Mathias C, Daniel SE (1994) “Minimal change” multiple system atrophy. Mov Disord 9:161-166
-
(1994)
Multiple System Atrophy
, vol.9
, pp. 161-166
-
-
Wenning, G.K.1
Quinn, N.2
Magalhaes, M.3
Mathias, C.4
Daniel, S.E.5
-
178
-
-
54849425351
-
Multiple system atrophy: A primary oligodendrogliopathy
-
Wenning GK, Stefanova N, Jellinger KA, Poewe W, Schlossmacher MG (2008) Multiple system atrophy: a primary oligodendrogliopathy. Ann Neurol 64:239-246
-
(2008)
Ann Neurol
, vol.64
, pp. 239-246
-
-
Wenning, G.K.1
Stefanova, N.2
Jellinger, K.A.3
Poewe, W.4
Schlossmacher, M.G.5
-
180
-
-
0038452761
-
Oligodendrocytes promote neuronal survival and axonal length by distinct intracellular mechanisms: A novel role for oligodendrocyte-derived glial cell line-derived neurotrophic factor
-
Wilkins A, Majed H, Layfield R, Compston A, Chandran S (2003) Oligodendrocytes promote neuronal survival and axonal length by distinct intracellular mechanisms: a novel role for oligodendrocyte-derived glial cell line-derived neurotrophic factor. J Neurosci 23:4967-4974
-
(2003)
J Neurosci
, vol.23
, pp. 4967-4974
-
-
Wilkins, A.1
Majed, H.2
Layfield, R.3
Compston, A.4
Chandran, S.5
-
181
-
-
77955664249
-
Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson’s disease brains with and without dementia
-
Wills J, Jones J, Haggerty T, Duka V, Joyce JN, Sidhu A (2010) Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson’s disease brains with and without dementia. Exp Neurol 225:210-218
-
(2010)
Exp Neurol
, vol.225
, pp. 210-218
-
-
Wills, J.1
Jones, J.2
Haggerty, T.3
Duka, V.4
Joyce, J.N.5
Sidhu, A.6
-
182
-
-
81455160328
-
A tangled web - tau and sporadic Parkinson’s disease
-
Wray S, Lewis PA (2010) A tangled web - tau and sporadic Parkinson’s disease. Front Psychiatry 1:150
-
(2010)
Front Psychiatry
, vol.1
, pp. 150
-
-
Wray, S.1
Lewis, P.A.2
-
183
-
-
2442694184
-
Probable multiple system atrophy in a German family
-
Wullner U, Abele M, Schmitz-Huebsch T, Wilhelm K, Benecke R, Deuschl G, Klockgether T (2004) Probable multiple system atrophy in a German family. J Neurol Neurosurg Psychiatry 75:924-925
-
(2004)
J Neurol Neurosurg Psychiatry
, vol.75
, pp. 924-925
-
-
Wullner, U.1
Abele, M.2
Schmitz-Huebsch, T.3
Wilhelm, K.4
Benecke, R.5
Deuschl, G.6
Klockgether, T.7
-
184
-
-
64749083242
-
Definite multiple system atrophy in a German family
-
Wullner U, Schmitt I, Kammal M, Kretzschmar HA, Neumann M (2009) Definite multiple system atrophy in a German family. J Neurol Neurosurg Psychiatry 80:449-450
-
(2009)
J Neurol Neurosurg Psychiatry
, vol.80
, pp. 449-450
-
-
Wullner, U.1
Schmitt, I.2
Kammal, M.3
Kretzschmar, H.A.4
Neumann, M.5
-
185
-
-
77956699395
-
New insights into the role of mitochondrial dysfunction and protein aggregation in Parkinson’s disease
-
Xie W, Wan OW, Chung KK (2010) New insights into the role of mitochondrial dysfunction and protein aggregation in Parkinson’s disease. Biochim Biophys Acta 1802:935-941
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 935-941
-
-
Xie, W.1
Wan, O.W.2
Chung, K.K.3
-
186
-
-
12744262948
-
No association between FMR1 premutations and multiple system atrophy
-
Yabe I, Soma H, Takei A, Fujik N, Sasaki H (2004) No association between FMR1 premutations and multiple system atrophy. J Neurol 251:1411-1412
-
(2004)
J Neurol
, vol.251
, pp. 1411-1412
-
-
Yabe, I.1
Soma, H.2
Takei, A.3
Fujik, N.4
Sasaki, H.5
-
187
-
-
15444376598
-
Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration
-
Yazawa I, Giasson BI, Sasaki R, Zhang B, Joyce S, Uryu K, Trojanowski JQ, Lee VM (2005) Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration. Neuron 45:847-859
-
(2005)
Neuron
, vol.45
, pp. 847-859
-
-
Yazawa, I.1
Giasson, B.I.2
Sasaki, R.3
Zhang, B.4
Joyce, S.5
Uryu, K.6
Trojanowski, J.Q.7
Lee, V.M.8
-
188
-
-
34648813113
-
Multiple system atrophy: Alpha-synuclein and neuronal degeneration
-
Yoshida M (2007) Multiple system atrophy: alpha-synuclein and neuronal degeneration. Neuropathology 27:484-493
-
(2007)
Neuropathology
, vol.27
, pp. 484-493
-
-
Yoshida, M.1
-
189
-
-
76149123541
-
The spectrum of mutations in progranulin: A collaborative study screening 545 cases of neurodegeneration
-
Yu CE, Bird TD, Bekris LM, Montine TJ, Leverenz JB, Steinbart E, Galloway NM, Feldman H, Woltjer R, Miller CA, Wood EM, Grossman M, Mc Cluskey L, Clark CM, Neumann M, Danek A, Galasko DR, Arnold SE, Chen-Plotkin A, Karydas A, Miller BL, Trojanowski JQ, Lee VM, Schellenberg GD, van Deerlin VM (2010) The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. Arch Neurol 67:161-170
-
(2010)
Arch Neurol
, vol.67
, pp. 161-170
-
-
Yu, C.E.1
Bird, T.D.2
Bekris, L.M.3
Montine, T.J.4
Leverenz, J.B.5
Steinbart, E.6
Galloway, N.M.7
Feldman, H.8
Woltjer, R.9
Miller, C.A.10
Wood, E.M.11
Grossman, M.12
Mc Cluskey, L.13
Clark, C.M.14
Neumann, M.15
Danek, A.16
Galasko, D.R.17
Arnold, S.E.18
Chen-Plotkin, A.19
Karydas, A.20
Miller, B.L.21
Trojanowski, J.Q.22
Lee, V.M.23
Schellenberg, G.D.24
Van Deerlin, V.M.25
more..
-
190
-
-
0036131896
-
The mitochondrial common deletion in Parkinson’s disease and related movement disorders
-
Zhang J, Montine TJ, Smith MA, Siedlak SL, Gu G, Robertson D, Perry G (2002) The mitochondrial common deletion in Parkinson’s disease and related movement disorders. Parkinsonism Relat Disord 8:165-170
-
(2002)
Parkinsonism Relat Disord
, vol.8
, pp. 165-170
-
-
Zhang, J.1
Montine, T.J.2
Smith, M.A.3
Siedlak, S.L.4
Gu, G.5
Robertson, D.6
Perry, G.7
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