Perioperative Dexamethasone Administration Does Not Increase the Incidence of Postoperative Infection in Total Hip and Knee Arthroplasty: A Retrospective Analysis

Journal of Arthroplasty

Volumn 31, Issue 8, 2016, Pages 1784-1787

  Richardson, Andrew B ^a   Bala, Abiram ^a   Wellman, Samuel S ^a   Attarian, David E ^b   Bolognesi, Michael P ^a   Grant, Stuart A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

anaesthesia; dexamethasone; periprosthetic infection; postoperative infection; retrospective

Indexed keywords

DEXAMETHASONE;

ADULT; ARTICLE; COAGULASE NEGATIVE STAPHYLOCOCCUS; DEBRIDEMENT; DRUG EFFICACY; DRUG RESPONSE; HUMAN; INCIDENCE; KNEE ARTHROPLASTY; MAJOR CLINICAL STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; PERIOPERATIVE PERIOD; PERIPROSTHETIC JOINT INFECTION; POSTOPERATIVE NAUSEA AND VOMITING; RETROSPECTIVE STUDY; STAPHYLOCOCCUS AUREUS; TOTAL HIP PROSTHESIS; TREATMENT OUTCOME; WOUND DEHISCENCE; WOUND DRAINAGE; AGED; FEMALE; HIP REPLACEMENT; INFECTION; KNEE REPLACEMENT; MALE; MIDDLE AGED; POSTOPERATIVE PERIOD; PROCEDURES;

AGED; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; DEXAMETHASONE; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PERIOPERATIVE PERIOD; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PERIOD; PROSTHESIS-RELATED INFECTIONS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84956913543     PISSN: 08835403     EISSN: 15328406     Source Type: Journal    
DOI: 10.1016/j.arth.2016.01.028     Document Type: Article

References (26)

1. 1 Callahan, C.M., Drake, B.G., Heck, D.A., et al. Patient outcomes following tricompartmental total knee replacement. A meta-analysis. JAMA, 271(17), 1994, 1349.
2. 2 Kurtz, S., Ong, K., Lau, E., et al. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am, 89(4), 2007, 780.
3. 3 Losina, E., Thornhill, T.S., Rome, B.N., et al. The dramatic increase in total knee replacement utilization rates in the United States cannot be fully explained by growth in population size and the obesity epidemic. J Bone Joint Surg Am, 94(3), 2012, 201.
4. 4 Capdevila, X., Barthelet, Y., Biboulet, P., et al. Effects of perioperative analgesic technique on the surgical outcome and duration of rehabilitation after major knee surgery. Anesthesiology, 91(1), 1999, 8.
5. 5 Dorr, L.D., Chao, L., The emotional state of the patient after total hip and knee arthroplasty. Clin Orthop Relat Res, 463, 2007, 7.
6. 6 Morrison, R.S., Magaziner, J., McLaughlin, M.A., et al. The impact of post-operative pain on outcomes following hip fracture. Pain, 103(3), 2003, 303.
7. 7 Parvizi, J., Miller, A.G., Gandhi, K., Multimodal pain management after total joint arthroplasty. J Bone Joint Surg Am, 93(11), 2011, 1075.
8. 8 den Hartog, Y.M., Mathijssen, N.M., Vehmeijer, S.B., Reduced length of hospital stay after the introduction of a rapid recovery protocol for primary THA procedures. Acta Orthop, 84(5), 2013, 444.
9. 9 Ibrahim, M.S., Twaij, H., Giebaly, D.E., et al. Enhanced recovery in total hip replacement: a clinical review. Bone Joint J, 95-b(12), 2013, 1587.
10. 10 Lamplot, J.D., Wagner, E.R., Manning, D.W., Multimodal pain management in total knee arthroplasty: a prospective randomized controlled trial. J Arthroplasty, 29(2), 2014, 329.
11. 11 Parvizi, J., Pain management following total joint arthroplasty: making strides. J Bone Joint Surg Am, 94(16), 2012, 1441.
12. 12 Parvizi, J., Bloomfield, M.R., Multimodal pain management in orthopedics: implications for joint arthroplasty surgery. Orthopedics, 36(2 Suppl), 2013, 7.
13. 13 Sculco, P.K., Pagnano, M.W., Perioperative solutions for rapid recovery joint arthroplasty: get ahead and stay ahead. J Arthroplasty, 30(4), 2015, 518.
14. 14 Stambough, J.B., Nunley, R.M., Curry, M.C., et al. Rapid recovery protocols for primary total hip arthroplasty can safely reduce length of stay without increasing readmissions. J Arthroplasty, 30(4), 2015, 521.
15. 15 De Oliveira, G.S. Jr., Castro-Alves, L.J., Ahmad, S., et al. Dexamethasone to prevent postoperative nausea and vomiting: an updated meta-analysis of randomized controlled trials. Anesth Analg, 116(1), 2013, 58.
16. 16 Koh, I.J., Chang, C.B., Lee, J.H., et al. Preemptive low-dose dexamethasone reduces postoperative emesis and pain after TKA: a randomized controlled study. Clin Orthop Relat Res, 471(9), 2013, 3010.
17. 17 Lunn, T.H., Kehlet, H., Perioperative glucocorticoids in hip and knee surgery—benefit vs. harm? A review of randomized clinical trials. Acta Anaesthesiol Scand, 57(7), 2013, 823.
18. 18 Lunn, T.H., Kristensen, B.B., Andersen, L.O., et al. Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial. Br J Anaesth, 106(2), 2011, 230.
19. 19 Waldron, N.H., Jones, C.A., Gan, T.J., et al. Impact of perioperative dexamethasone on postoperative analgesia and side-effects: systematic review and meta-analysis. Br J Anaesth, 110(2), 2013, 191.
20. 20 Corcoran, T.B., Edwards, T., A survey of antiemetic dexamethasone administration-frequency of use and perceptions of benefits and risks. Anaesth Intensive Care, 43(2), 2015, 167.
21. 21 Stahn, C., Buttgereit, F., Genomic and nongenomic effects of glucocorticoids. Nat Clin Pract Rheumatol, 4(10), 2008, 525.
22. 22 Short, T.G., Leslie, K., Dexamethasone-an effective antiemetic, but is it safe?. Anaesth Intensive Care, 43(2), 2015, 155.
23. 23 Backes, J.R., Bentley, J.C., Politi, J.R., et al. Dexamethasone reduces length of hospitalization and improves postoperative pain and nausea after total joint arthroplasty: a prospective, randomized controlled trial. J Arthroplasty, 28(8 Suppl), 2013, 11.
24. 24 Ikeuchi, M., Kamimoto, Y., Izumi, M., et al. Effects of dexamethasone on local infiltration analgesia in total knee arthroplasty: a randomized controlled trial. Knee Surg Sports Traumatol Arthrosc, 22(7), 2014, 1638.
25. 25 Wang, C., Cai, X.Z., Yan, S.G., Comparison of periarticular multimodal drug injection and femoral nerve block for postoperative pain management in total knee arthroplasty: a systematic review and meta-analysis. J Arthroplasty, 30(7), 2015, 1281.
26. 26 Yue, D.B., Wang, B.L., Liu, K.P., et al. Efficacy of multimodal cocktail periarticular injection with or without steroid in total knee arthroplasty. Chin Med J, 126(20), 2013, 3851.