Pharmacokinetics and brain penetration of carbapenems in mice

Journal of Infection and Chemotherapy

Volumn 22, Issue 5, 2016, Pages 346-349

  Matsumoto, Kazuaki ^a   Kurihara, Yuji ^a,b   Kuroda, Yuko ^a   Hori, Seiji ^c   Kizu, Junko ^a  

^a KEIO UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Brain penetration; Carbapenems; Pharmacokinetics

Indexed keywords

BIAPENEM; CARBAPENEM DERIVATIVE; CILASTATIN; DORIPENEM; IMIPENEM; MEROPENEM; ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BRAIN; BRAIN TISSUE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG PENETRATION; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MOUSE; NONHUMAN; ANIMAL; BRAIN CHEMISTRY; DRUG EFFECTS; METABOLISM; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BRAIN; BRAIN CHEMISTRY; CARBAPENEMS; INJECTIONS, SUBCUTANEOUS; MICE;

EID: 84956899643     PISSN: 1341321X     EISSN: 14377780     Source Type: Journal    
DOI: 10.1016/j.jiac.2015.11.010     Document Type: Article

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