-
1
-
-
33748111665
-
Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance
-
PMID: 16952562
-
Tilg H, Hotamisligil GS. Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance. Gastroenterology 2006; 131: 934-945. PMID: 16952562.
-
(2006)
Gastroenterology
, vol.131
, pp. 934-945
-
-
Tilg, H.1
Hotamisligil, G.S.2
-
3
-
-
84863986988
-
Mutations in LPL, APOC2, APOA5, GPIHBP1 and LMF1 in patients with severe hypertriglyceridaemia
-
PMID: 22239554
-
Surendran RP, Visser ME, Heemelaar S, Wang J, Peter J, Defesche JC, et al. Mutations in LPL, APOC2, APOA5, GPIHBP1 and LMF1 in patients with severe hypertriglyceridaemia. J Intern Med 2012; 272: 185-196. doi:10.1111/j.1365-2796.2012.02516.x PMID: 22239554.
-
(2012)
J Intern Med
, vol.272
, pp. 185-196
-
-
Surendran, R.P.1
Visser, M.E.2
Heemelaar, S.3
Wang, J.4
Peter, J.5
Defesche, J.C.6
-
4
-
-
80055008025
-
Apolipoprotein A-V; a potent triglyceride reducer
-
PMID: 21831376
-
Nilsson SK, Heeren J, Olivecrona G, Merkel M. Apolipoprotein A-V; a potent triglyceride reducer. Atherosclerosis 2011; 219: 15-21. doi:10.1016/j.atherosclerosis.2011.07.019 PMID: 21831376.
-
(2011)
Atherosclerosis
, vol.219
, pp. 15-21
-
-
Nilsson, S.K.1
Heeren, J.2
Olivecrona, G.3
Merkel, M.4
-
5
-
-
84865142899
-
A new, powerful player in lipoprotein metabolism: Brown adipose tissue
-
Berl
-
Bartelt A, Merkel M, Heeren J. A new, powerful player in lipoprotein metabolism: brown adipose tissue. J Mol Med (Berl) 2012; 90: 887-893.
-
(2012)
J Mol Med
, vol.90
, pp. 887-893
-
-
Bartelt, A.1
Merkel, M.2
Heeren, J.3
-
6
-
-
46249093117
-
Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome
-
PMID: 18565848
-
Adiels M, Olofsson SO, Taskinen MR, Boren J. Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome. Arterioscler Thromb Vasc Biol 2008; 28: 1225-1236. doi:10.1161/ATVBAHA.107.160192 PMID: 18565848.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1225-1236
-
-
Adiels, M.1
Olofsson, S.O.2
Taskinen, M.R.3
Boren, J.4
-
7
-
-
84883266764
-
Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice
-
PMID: 23846497
-
Foley EM, Gordts PL, Stanford KI, Gonzales JC, Lawrence R, Stoddard N, et al. Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice. Arterioscler Thromb Vasc Biol 2013; 33: 2065-2074. doi:10.1161/ATVBAHA.113.301637 PMID: 23846497.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 2065-2074
-
-
Foley, E.M.1
Gordts, P.L.2
Stanford, K.I.3
Gonzales, J.C.4
Lawrence, R.5
Stoddard, N.6
-
8
-
-
67349108867
-
Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance
-
PMID: 18834984
-
Laatsch A, Merkel M, Talmud PJ, Grewal T, Beisiegel U, Heeren J. Insulin stimulates hepatic low density lipoprotein receptor-related protein 1 (LRP1) to increase postprandial lipoprotein clearance. Atherosclerosis 2009; 204: 105-111. doi:10.1016/j.atherosclerosis.2008.07.046 PMID: 18834984.
-
(2009)
Atherosclerosis
, vol.204
, pp. 105-111
-
-
Laatsch, A.1
Merkel, M.2
Talmud, P.J.3
Grewal, T.4
Beisiegel, U.5
Heeren, J.6
-
9
-
-
0022272793
-
Synthesis of apolipoprotein E by peripheral tissues. Potential functions in reverse cholesterol transport and cellular cholesterol metabolism
-
PMID: 3907463
-
Williams DL, Dawson PA, Newman TC, Rudel LL. Synthesis of apolipoprotein E by peripheral tissues. Potential functions in reverse cholesterol transport and cellular cholesterol metabolism. Ann N Y Acad Sci 1985; 454: 222-229. PMID: 3907463.
-
(1985)
Ann N Y Acad Sci
, vol.454
, pp. 222-229
-
-
Williams, D.L.1
Dawson, P.A.2
Newman, T.C.3
Rudel, L.L.4
-
10
-
-
0028641565
-
Role of HDL apolipoprotein E in cellular cholesterol efflux: Studies in apo E knockout transgenic mice
-
PMID: 7802634
-
Hayek T, Oiknine J, Brook JG, Aviram M. Role of HDL apolipoprotein E in cellular cholesterol efflux: studies in apo E knockout transgenic mice. Biochem Biophys Res Commun 1994; 205: 1072-1078. PMID: 7802634.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1072-1078
-
-
Hayek, T.1
Oiknine, J.2
Brook, J.G.3
Aviram, M.4
-
11
-
-
33646544088
-
Apolipoprotein E recycling: Implications for dyslipidemia and atherosclerosis
-
PMID: 16373604
-
Heeren J, Beisiegel U, Grewal T. Apolipoprotein E recycling: implications for dyslipidemia and atherosclerosis. Arterioscler Thromb Vasc Biol 2006; 26: 442-448. PMID: 16373604.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 442-448
-
-
Heeren, J.1
Beisiegel, U.2
Grewal, T.3
-
12
-
-
0026725757
-
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
-
PMID: 1423598
-
Plump AS, Smith JD, Hayek T, Aalto-Setala K, Walsh A, Verstuyft JG, et al. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 1992; 71: 343-353. PMID: 1423598.
-
(1992)
Cell
, vol.71
, pp. 343-353
-
-
Plump, A.S.1
Smith, J.D.2
Hayek, T.3
Aalto-Setala, K.4
Walsh, A.5
Verstuyft, J.G.6
-
13
-
-
2942520978
-
Atherosclerosis in the apolipoprotein-E-deficient mouse: A decade of progress
-
PMID: 15087308
-
Meir KS, Leitersdorf E. Atherosclerosis in the apolipoprotein-E-deficient mouse: A decade of progress. Arterioscler Thromb Vasc Biol 2004; 24: 1006-1014. PMID: 15087308.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1006-1014
-
-
Meir, K.S.1
Leitersdorf, E.2
-
14
-
-
0026592806
-
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
-
PMID: 1411543
-
Zhang SH, Reddick RL, Piedrahita JA, Maeda N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992; 258: 468-471. PMID: 1411543.
-
(1992)
Science
, vol.258
, pp. 468-471
-
-
Zhang, S.H.1
Reddick, R.L.2
Piedrahita, J.A.3
Maeda, N.4
-
15
-
-
0033544863
-
Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver
-
PMID: 10585451
-
Mensenkamp AR, Jong MC, van Goor H, van Luyn MJ, Bloks V, Havinga R, et al. Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver. J Biol Chem 1999; 274: 35711-35718. PMID: 10585451.
-
(1999)
J Biol Chem
, vol.274
, pp. 35711-35718
-
-
Mensenkamp, A.R.1
Jong, M.C.2
Van Goor, H.3
Van Luyn, M.J.4
Bloks, V.5
Havinga, R.6
-
16
-
-
0031467633
-
Impaired secretion of very low density lipoprotein- Triglycerides by apolipoprotein E- deficient mouse hepatocytes
-
PMID: 9389759
-
Kuipers F, Jong MC, Lin Y, Eck M, Havinga R, Bloks V, et al. Impaired secretion of very low density lipoprotein- Triglycerides by apolipoprotein E- deficient mouse hepatocytes. J Clin Invest 1997; 100: 2915- 2922. PMID: 9389759.
-
(1997)
J Clin Invest
, vol.100
, pp. 2915-2922
-
-
Kuipers, F.1
Jong, M.C.2
Lin, Y.3
Eck, M.4
Havinga, R.5
Bloks, V.6
-
17
-
-
15644366977
-
Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia
-
PMID: 9756870
-
Huang Y, Liu XQ, Rall SC Jr., Taylor JM, von Eckardstein A, Assmann G, et al. Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia. J Biol Chem 1998; 273: 26388- 26393. PMID: 9756870.
-
(1998)
J Biol Chem
, vol.273
, pp. 26388-26393
-
-
Huang, Y.1
Liu, X.Q.2
Rall, S.C.3
Taylor, J.M.4
Von, E.A.5
Assmann, G.6
-
18
-
-
38449108309
-
Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice
-
PMID: 17914034
-
Hofmann SM, Perez-Tilve D, Greer TM, Coburn BA, Grant E, Basford JE, et al. Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice. Diabetes 2008; 57: 5-12. PMID: 17914034.
-
(2008)
Diabetes
, vol.57
, pp. 5-12
-
-
Hofmann, S.M.1
Perez-Tilve, D.2
Greer, T.M.3
Coburn, B.A.4
Grant, E.5
Basford, J.E.6
-
19
-
-
77956408745
-
Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: Modulation by dietinduced obesity
-
PMID: 20633710
-
Bartelt A, Beil FT, Schinke T, Roeser K, Ruether W, Heeren J, et al. Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by dietinduced obesity. Bone 2010; 47: 736-745. doi:10.1016/j.bone.2010.07.002 PMID: 20633710.
-
(2010)
Bone
, vol.47
, pp. 736-745
-
-
Bartelt, A.1
Beil, F.T.2
Schinke, T.3
Roeser, K.4
Ruether, W.5
Heeren, J.6
-
20
-
-
80054692396
-
Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: Relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance
-
PMID: 21847582
-
Bartelt A, Orlando P, Mele C, Ligresti A, Toedter K, Scheja L, et al. Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance. Diabetologia 2011; 54: 2900-2910. doi:10.1007/s00125-011-2274-6 PMID: 21847582.
-
(2011)
Diabetologia
, vol.54
, pp. 2900-2910
-
-
Bartelt, A.1
Orlando, P.2
Mele, C.3
Ligresti, A.4
Toedter, K.5
Scheja, L.6
-
21
-
-
0019305073
-
Production of apolipoproteins E and A-I by rat hepatocytes in primary culture
-
PMID: 6769496
-
Dashti N, McConathy WJ, Ontko JA. Production of apolipoproteins E and A-I by rat hepatocytes in primary culture. Biochim Biophys Acta 1980; 618: 347-358. PMID: 6769496.
-
(1980)
Biochim Biophys Acta
, vol.618
, pp. 347-358
-
-
Dashti, N.1
McConathy, W.J.2
Ontko, J.A.3
-
22
-
-
0028944150
-
Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation
-
PMID: 7863332
-
Linton MF, Atkinson JB, Fazio S. Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation. Science 1995; 267: 1034-1037. PMID: 7863332.
-
(1995)
Science
, vol.267
, pp. 1034-1037
-
-
Linton, M.F.1
Atkinson, J.B.2
Fazio, S.3
-
23
-
-
0029081525
-
Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation
-
PMID: 7635947
-
Boisvert WA, Spangenberg J, Curtiss LK. Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation. J Clin Invest 1995; 96: 1118-1124. PMID: 7635947.
-
(1995)
J Clin Invest
, vol.96
, pp. 1118-1124
-
-
Boisvert, W.A.1
Spangenberg, J.2
Curtiss, L.K.3
-
24
-
-
0025821171
-
Apolipoprotein E gene expression in mouse 3T3-L1 adipocytes and human adipose tissue and its regulation by differentiation and lipid content
-
PMID: 1709937
-
Zechner R, Moser R, Newman TC, Fried SK, Breslow JL. Apolipoprotein E gene expression in mouse 3T3-L1 adipocytes and human adipose tissue and its regulation by differentiation and lipid content. J Biol Chem 1991; 266: 10583-10588. PMID: 1709937.
-
(1991)
J Biol Chem
, vol.266
, pp. 10583-10588
-
-
Zechner, R.1
Moser, R.2
Newman, T.C.3
Fried, S.K.4
Breslow, J.L.5
-
25
-
-
4143091289
-
Apolipoprotein E: Diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease
-
PMID: 15181247
-
Huang Y, Weisgraber KH, Mucke L, Mahley RW. Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease. J Mol Neurosci 2004; 23: 189- 204. PMID: 15181247.
-
(2004)
J Mol Neurosci
, vol.23
, pp. 189-204
-
-
Huang, Y.1
Weisgraber, K.H.2
Mucke, L.3
Mahley, R.W.4
-
26
-
-
33845535487
-
Endogenous ApoE expression modulates adipocyte triglyceride content and turnover
-
PMID: 17130485
-
Huang ZH, Reardon CA, Mazzone T. Endogenous ApoE expression modulates adipocyte triglyceride content and turnover. Diabetes 2006; 55: 3394-3402. PMID: 17130485.
-
(2006)
Diabetes
, vol.55
, pp. 3394-3402
-
-
Huang, Z.H.1
Reardon, C.A.2
Mazzone, T.3
-
27
-
-
66149148592
-
Role of adipocyte-derived apoE in modulating adipocyte size, lipid metabolism, and gene expression in vivo
-
PMID: 19223650
-
Huang ZH, Gu D, Mazzone T. Role of adipocyte-derived apoE in modulating adipocyte size, lipid metabolism, and gene expression in vivo. Am J Physiol Endocrinol Metab 2009; 296: E1110-E1119. doi:10.1152/ajpendo.90964.2008 PMID: 19223650.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, pp. E1110-E1119
-
-
Huang, Z.H.1
Gu, D.2
Mazzone, T.3
-
28
-
-
43149088247
-
Recycling of apolipoprotein E is not associated with cholesterol efflux in neuronal cells
-
PMID: 18359298
-
Rellin L, Heeren J, Beisiegel U. Recycling of apolipoprotein E is not associated with cholesterol efflux in neuronal cells. Biochim Biophys Acta 2008; 1781: 232-238. doi:10.1016/j.bbalip.2008.02.001 PMID: 18359298.
-
(2008)
Biochim Biophys Acta
, vol.1781
, pp. 232-238
-
-
Rellin, L.1
Heeren, J.2
Beisiegel, U.3
-
29
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
PMID: 11846609
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408. PMID: 11846609.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
30
-
-
0035742829
-
Hepatic steatosis and very low density lipoprotein secretion: The involvement of apolipoprotein E
-
PMID: 11738112
-
Mensenkamp AR, Havekes LM, Romijn JA, Kuipers F. Hepatic steatosis and very low density lipoprotein secretion: The involvement of apolipoprotein E. J Hepatol 2001; 35: 816-822. PMID: 11738112.
-
(2001)
J Hepatol
, vol.35
, pp. 816-822
-
-
Mensenkamp, A.R.1
Havekes, L.M.2
Romijn, J.A.3
Kuipers, F.4
-
31
-
-
49649110937
-
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
-
PMID: 18666236
-
Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, Lutjohann D, et al. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology 2008; 48: 474-486. doi:10.1002/hep.22363 PMID: 18666236.
-
(2008)
Hepatology
, vol.48
, pp. 474-486
-
-
Wouters, K.1
Van Gorp, P.J.2
Bieghs, V.3
Gijbels, M.J.4
Duimel, H.5
Lutjohann, D.6
-
32
-
-
79751503329
-
Brown adipose tissue activity controls triglyceride clearance
-
PMID: 21258337
-
Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, et al. Brown adipose tissue activity controls triglyceride clearance. Nat Med 2011; 17: 200-205. doi:10.1038/nm.2297 PMID: 21258337.
-
(2011)
Nat Med
, vol.17
, pp. 200-205
-
-
Bartelt, A.1
Bruns, O.T.2
Reimer, R.3
Hohenberg, H.4
Ittrich, H.5
Peldschus, K.6
-
33
-
-
84871234634
-
ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice
-
PMID: 23071294
-
Huang ZH, Reardon CA, Subbaiah PV, Getz GS, Mazzone T. ApoE derived from adipose tissue does not suppress atherosclerosis or correct hyperlipidemia in apoE knockout mice. J Lipid Res 2013; 54: 202-213. doi:10.1194/jlr.M031906 PMID: 23071294.
-
(2013)
J Lipid Res
, vol.54
, pp. 202-213
-
-
Huang, Z.H.1
Reardon, C.A.2
Subbaiah, P.V.3
Getz, G.S.4
Mazzone, T.5
-
34
-
-
84871750212
-
A novel adipose-specific gene deletion model demonstrates potential pitfalls of existing methods
-
PMID: 23192980
-
Mullican SE, Tomaru T, Gaddis CA, Peed LC, Sundaram A, Lazar MA. A novel adipose-specific gene deletion model demonstrates potential pitfalls of existing methods. Mol Endocrinol 2013; 27: 127-134. doi:10.1210/me.2012-1267 PMID: 23192980.
-
(2013)
Mol Endocrinol
, vol.27
, pp. 127-134
-
-
Mullican, S.E.1
Tomaru, T.2
Gaddis, C.A.3
Peed, L.C.4
Sundaram, A.5
Lazar, M.A.6
-
35
-
-
84923793571
-
Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells
-
PMID: 25458893
-
Krueger KC, Costa MJ, Du H, Feldman BJ. Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells. Stem Cell Reports 2014; 3: 1147-1158. doi:10.1016/j.stemcr.2014.10.009 PMID: 25458893.
-
(2014)
Stem Cell Reports
, vol.3
, pp. 1147-1158
-
-
Krueger, K.C.1
Costa, M.J.2
Du, H.3
Feldman, B.J.4
-
36
-
-
56749164791
-
Nutrient sensing and inflammation in metabolic diseases
-
PMID: 19029988
-
Hotamisligil GS, Erbay E. Nutrient sensing and inflammation in metabolic diseases. Nat Rev Immunol 2008; 8: 923-934. doi:10.1038/nri2449 PMID: 19029988.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 923-934
-
-
Hotamisligil, G.S.1
Erbay, E.2
|