-
1
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC etal. EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
-
2
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R etal. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
3
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M etal. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004; 101: 13306-13311.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
4
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S etal. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009; 361: 947-957.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
5
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
-
Mitsudomi T, Morita S, Yatabe Y etal. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial. Lancet Oncol 2010; 11: 121-128.
-
(2010)
Lancet Oncol
, vol.11
, pp. 121-128
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
-
6
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
-
Zhou C, Wu YL, Chen G etal. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011; 12: 735-742.
-
(2011)
Lancet Oncol
, vol.12
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
-
7
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
-
Rosell R, Carcereny E, Gervais R etal. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012; 13: 239-246.
-
(2012)
Lancet Oncol
, vol.13
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
-
8
-
-
80055009292
-
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
-
Stacey SN, Sulem P, Jonasdottir A etal. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet 2011; 43: 1098-1103.
-
(2011)
Nat Genet
, vol.43
, pp. 1098-1103
-
-
Stacey, S.N.1
Sulem, P.2
Jonasdottir, A.3
-
9
-
-
84865569656
-
Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients
-
Xiong D, Li G, Li K etal. Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients. Carcinogenesis 2012; 33: 1797-1805.
-
(2012)
Carcinogenesis
, vol.33
, pp. 1797-1805
-
-
Xiong, D.1
Li, G.2
Li, K.3
-
10
-
-
84865168855
-
Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing
-
Liu P, Morrison C, Wang L etal. Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis 2012; 33: 1270-1276.
-
(2012)
Carcinogenesis
, vol.33
, pp. 1270-1276
-
-
Liu, P.1
Morrison, C.2
Wang, L.3
-
11
-
-
84905660513
-
Next-generation sequencing reveals a Novel NSCLC ALK F1174V mutation and confirms ALK G1202R mutation confers high-level resistance to alectinib (CH5424802/RO5424802) in ALK-rearranged NSCLC patients who progressed on crizotinib
-
Ignatius Ou SH, Azada M, Hsiang DJ etal. Next-generation sequencing reveals a Novel NSCLC ALK F1174V mutation and confirms ALK G1202R mutation confers high-level resistance to alectinib (CH5424802/RO5424802) in ALK-rearranged NSCLC patients who progressed on crizotinib. J Thorac Oncol 2014; 9: 549-553.
-
(2014)
J Thorac Oncol
, vol.9
, pp. 549-553
-
-
Ignatius Ou, S.H.1
Azada, M.2
Hsiang, D.J.3
-
12
-
-
33745560074
-
The US Food and Drug Administration perspective on cancer biomarker development
-
Gutman S, Kessler LG. The US Food and Drug Administration perspective on cancer biomarker development. Nat Rev Cancer 2006; 6: 565-571.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 565-571
-
-
Gutman, S.1
Kessler, L.G.2
-
13
-
-
79952015320
-
US FDA perspective on challenges in co-developing in vitro companion diagnostics and targeted cancer therapeutics
-
Philip R, Carrington L, Chan M. US FDA perspective on challenges in co-developing in vitro companion diagnostics and targeted cancer therapeutics. Bioanalysis 2011; 3: 383-389.
-
(2011)
Bioanalysis
, vol.3
, pp. 383-389
-
-
Philip, R.1
Carrington, L.2
Chan, M.3
-
14
-
-
65949099336
-
A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro
-
Daniel VC, Marchionni L, Hierman JS etal. A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro. Cancer Res 2009; 69: 3364-3373.
-
(2009)
Cancer Res
, vol.69
, pp. 3364-3373
-
-
Daniel, V.C.1
Marchionni, L.2
Hierman, J.S.3
-
15
-
-
0141566685
-
Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models
-
Voskoglou-Nomikos T, Pater JL, Seymour L. Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models. Clin Cancer Res 2003; 9: 4227-4239.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4227-4239
-
-
Voskoglou-Nomikos, T.1
Pater, J.L.2
Seymour, L.3
-
16
-
-
68749085806
-
Patient-derived xenografts of non-small-cell lung cancer: A pre-clinical model to evaluate adjuvant chemotherapy?
-
Merk J, Rolff J, Becker M, Leschber G, Fichtner I. Patient-derived xenografts of non-small-cell lung cancer: A pre-clinical model to evaluate adjuvant chemotherapy? Eur J Cardiothorac Surg 2009; 36: 454-459.
-
(2009)
Eur J Cardiothorac Surg
, vol.36
, pp. 454-459
-
-
Merk, J.1
Rolff, J.2
Becker, M.3
Leschber, G.4
Fichtner, I.5
-
17
-
-
84897030891
-
Patient-derived sialyl-Tn-positive invasive bladder cancer xenografts in nude mice: An exploratory model study
-
Bernardo C, Costa C, Amaro T etal. Patient-derived sialyl-Tn-positive invasive bladder cancer xenografts in nude mice: An exploratory model study. Anticancer Res 2014; 34: 735-744.
-
(2014)
Anticancer Res
, vol.34
, pp. 735-744
-
-
Bernardo, C.1
Costa, C.2
Amaro, T.3
-
18
-
-
84887096419
-
Molecular characterization of patient-derived human pancreatic tumor xenograft models for preclinical and translational development of cancer therapeutics
-
Mattie M, Christensen A, Chang MS etal. Molecular characterization of patient-derived human pancreatic tumor xenograft models for preclinical and translational development of cancer therapeutics. Neoplasia 2013; 15: 1138-1150.
-
(2013)
Neoplasia
, vol.15
, pp. 1138-1150
-
-
Mattie, M.1
Christensen, A.2
Chang, M.S.3
-
19
-
-
84894275509
-
High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development
-
Lin D, Wyatt AW, Xue H etal. High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development. Cancer Res 2014; 74: 1272-1283.
-
(2014)
Cancer Res
, vol.74
, pp. 1272-1283
-
-
Lin, D.1
Wyatt, A.W.2
Xue, H.3
-
20
-
-
84880028845
-
Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: Useful tools for preclinical studies of targeted therapies
-
Zhang XC, Zhang J, Li M etal. Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: Useful tools for preclinical studies of targeted therapies. J Transl Med 2013; 11: 168.
-
(2013)
J Transl Med
, vol.11
, pp. 168
-
-
Zhang, X.C.1
Zhang, J.2
Li, M.3
-
21
-
-
84915797007
-
Suitability of surgical tumor tissues, biopsy, or cytology samples for epidermal growth factor receptor mutation testing in non-small cell lung carcinoma based on Chinese population
-
Han X, Zhang Z, Wu D etal. Suitability of surgical tumor tissues, biopsy, or cytology samples for epidermal growth factor receptor mutation testing in non-small cell lung carcinoma based on Chinese population. Transl Oncol 2014; 7: 795-799.
-
(2014)
Transl Oncol
, vol.7
, pp. 795-799
-
-
Han, X.1
Zhang, Z.2
Wu, D.3
-
22
-
-
84927578869
-
Clinical likelihood of sporadic primary EGFR T790M mutation in EGFR-mutant lung cancer
-
Lee Y, Lee GK, Hwang JA, Yun T, Kim HT, Lee JS. Clinical likelihood of sporadic primary EGFR T790M mutation in EGFR-mutant lung cancer. Clin Lung Cancer 2015; 16: 46-50.
-
(2015)
Clin Lung Cancer
, vol.16
, pp. 46-50
-
-
Lee, Y.1
Lee, G.K.2
Hwang, J.A.3
Yun, T.4
Kim, H.T.5
Lee, J.S.6
-
23
-
-
84924362694
-
Clinicopathological characteristics of patients with non-small-cell lung cancer who harbor EML4-ALK fusion gene: A meta-analysis
-
Zhao F, Xu M, Lei H etal. Clinicopathological characteristics of patients with non-small-cell lung cancer who harbor EML4-ALK fusion gene: A meta-analysis. PLoS ONE 2015; 10 (2): e0117333.
-
(2015)
PLoS ONE
, vol.10
, Issue.2
, pp. e0117333
-
-
Zhao, F.1
Xu, M.2
Lei, H.3
-
24
-
-
84897018525
-
Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients
-
Kim Y, Hammerman PS, Kim J etal. Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients. J Clin Oncol 2014; 32: 121-128.
-
(2014)
J Clin Oncol
, vol.32
, pp. 121-128
-
-
Kim, Y.1
Hammerman, P.S.2
Kim, J.3
-
25
-
-
66849091226
-
Epidermal growth factor receptor mutations in plasma DNA samples predict tumor response in Chinese patients with stages IIIB to IV non-small-cell lung cancer
-
Bai H, Mao L, Wang HS etal. Epidermal growth factor receptor mutations in plasma DNA samples predict tumor response in Chinese patients with stages IIIB to IV non-small-cell lung cancer. J Clin Oncol 2009; 27: 2653-2659.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2653-2659
-
-
Bai, H.1
Mao, L.2
Wang, H.S.3
-
26
-
-
84865442609
-
Influence of chemotherapy on EGFR mutation status among patients with non-small-cell lung cancer
-
Bai H, Wang Z, Chen K etal. Influence of chemotherapy on EGFR mutation status among patients with non-small-cell lung cancer. J Clin Oncol 2012; 30: 3077-3083.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3077-3083
-
-
Bai, H.1
Wang, Z.2
Chen, K.3
-
27
-
-
76749151984
-
Potential clinical significance of a plasma-based KRAS mutation analysis in patients with advanced non-small cell lung cancer
-
Wang S, An T, Wang J etal. Potential clinical significance of a plasma-based KRAS mutation analysis in patients with advanced non-small cell lung cancer. Clin Cancer Res 2010; 16: 1324-1330.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1324-1330
-
-
Wang, S.1
An, T.2
Wang, J.3
-
28
-
-
58149186087
-
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers
-
Fichtner I, Rolff J, Soong R etal. Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers. Clin Cancer Res 2008; 14: 6456-6468.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6456-6468
-
-
Fichtner, I.1
Rolff, J.2
Soong, R.3
-
29
-
-
79958001559
-
Chemoresistance in non-small-cell lung cancer: Can multidrug resistance markers predict the response of xenograft lung cancer models to chemotherapy?
-
Merk J, Rolff J, Dorn C, Leschber G, Fichtner I. Chemoresistance in non-small-cell lung cancer: Can multidrug resistance markers predict the response of xenograft lung cancer models to chemotherapy? Eur J Cardiothorac Surg 2011; 40: e29-33.
-
(2011)
Eur J Cardiothorac Surg
, vol.40
, pp. e29-e33
-
-
Merk, J.1
Rolff, J.2
Dorn, C.3
Leschber, G.4
Fichtner, I.5
-
30
-
-
78751471036
-
The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer
-
John T, Kohler D, Pintilie M etal. The ability to form primary tumor xenografts is predictive of increased risk of disease recurrence in early-stage non-small cell lung cancer. Clin Cancer Res 2011; 17: 134-141.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 134-141
-
-
John, T.1
Kohler, D.2
Pintilie, M.3
-
31
-
-
77954347979
-
Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
Sorensen M, Pijls-Johannesma M, Felip E. Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010; 21: v120-125.
-
(2010)
Ann Oncol
, vol.21
, pp. v120-v125
-
-
Sorensen, M.1
Pijls-Johannesma, M.2
Felip, E.3
-
32
-
-
0346667037
-
Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: A clinicopathologic and immunohistochemical study of 75 cases
-
Rossi G, Cavazza A, Sturm N etal. Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: A clinicopathologic and immunohistochemical study of 75 cases. Am J Surg Pathol 2003; 27: 311-324.
-
(2003)
Am J Surg Pathol
, vol.27
, pp. 311-324
-
-
Rossi, G.1
Cavazza, A.2
Sturm, N.3
-
34
-
-
84879885432
-
EML4-ALK translocation in both metachronous second primary lung sarcomatoid carcinoma and lung adenocarcinoma: A case report
-
Ali G, Proietti A, Niccoli C etal. EML4-ALK translocation in both metachronous second primary lung sarcomatoid carcinoma and lung adenocarcinoma: A case report. Lung Cancer 2013; 81: 297-301.
-
(2013)
Lung Cancer
, vol.81
, pp. 297-301
-
-
Ali, G.1
Proietti, A.2
Niccoli, C.3
-
35
-
-
84880894511
-
Transformation to sarcomatoid carcinoma in ALK-rearranged adenocarcinoma, which developed acquired resistance to crizotinib and received subsequent chemotherapies
-
Kobayashi Y, Sakao Y, Ito S etal. Transformation to sarcomatoid carcinoma in ALK-rearranged adenocarcinoma, which developed acquired resistance to crizotinib and received subsequent chemotherapies. J Thorac Oncol 2013; 8: e75-78.
-
(2013)
J Thorac Oncol
, vol.8
, pp. e75-e78
-
-
Kobayashi, Y.1
Sakao, Y.2
Ito, S.3
-
36
-
-
78650451788
-
Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
-
Weiss J, Sos ML, Seidel D etal. Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med 2010; 2: 62ra93.
-
(2010)
Sci Transl Med
, vol.2
, pp. 62ra93
-
-
Weiss, J.1
Sos, M.L.2
Seidel, D.3
-
37
-
-
84874888512
-
Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer
-
Kim HR, Kim DJ, Kang DR etal. Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer. J Clin Oncol 2013; 31: 731-737.
-
(2013)
J Clin Oncol
, vol.31
, pp. 731-737
-
-
Kim, H.R.1
Kim, D.J.2
Kang, D.R.3
-
38
-
-
84896333670
-
Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing
-
McFadden DG, Papagiannakopoulos T, Taylor-Weiner A etal. Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing. Cell 2014; 156: 1298-1311.
-
(2014)
Cell
, vol.156
, pp. 1298-1311
-
-
McFadden, D.G.1
Papagiannakopoulos, T.2
Taylor-Weiner, A.3
-
39
-
-
84861550476
-
The life history of 21 breast cancers
-
Nik-Zainal S, Van Loo P, Wedge DC etal. The life history of 21 breast cancers. Cell 2012; 149: 994-1007.
-
(2012)
Cell
, vol.149
, pp. 994-1007
-
-
Nik-Zainal, S.1
Van Loo, P.2
Wedge, D.C.3
|