Not just loading and age: The dynamics of osteoarthritis, obesity and inflammation

Medical Journal of Australia

Volumn 204, Issue 2, 2016, Pages 47-47.e1

  Cicuttini, Flavia M ^a   Wluka, Anita E ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; CYTOKINE; LEPTIN;

AGED; AGING; BODY COMPOSITION; CARDIOVASCULAR DISEASE; COMORBIDITY; DISEASE SEVERITY; EDITORIAL; HUMAN; INFLAMMATION; MORBIDITY; OBESITY; OSTEOARTHRITIS; PAIN ASSESSMENT; RISK FACTOR; BODY MASS; COMPLICATION; LIFESTYLE; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; WEIGHT GAIN;

BODY COMPOSITION; BODY MASS INDEX; HUMANS; INFLAMMATION; LIFE STYLE; MAGNETIC RESONANCE IMAGING; OBESITY; OSTEOARTHRITIS; RISK FACTORS; WEIGHT GAIN;

EID: 84956670117     PISSN: 0025729X     EISSN: 13265377     Source Type: Journal    
DOI: 10.5694/mja15.01069     Document Type: Editorial

References (10)

1. Mezhov V, Ciccuttini FM, Hanna FS, et al. Does obesity affect knee cartilage? A systematic review of magnetic resonance imaging data. Obes Rev 2014; 15: 143-157.
2. Urquhart DM, Berry P, Wluka AE, et al. 2011 Young Investigator Award winner: increased fat mass is associated with high levels of low back pain intensity and disability. Spine 2011; 36: 1320-1325.
3. Tanamas SK, Wluka AE, Berry P, et al. Relationship between obesity and foot pain and its association with fat mass, fat distribution, and muscle mass. Arthritis Care Res (Hoboken) 2012; 64: 262-268.
4. Gomez R, Lago F, Gomez-Reino J, et al. Adipokines in the skeleton: influence on cartilage function and joint degenerative diseases. J Mol Endocrinol 2009; 43: 11-18.
5. Pelletier JP, Raynauld JP, Caron J, et al. Decrease in serum level of matrix metalloproteinases is predictive of the disease-modifying effect of osteoarthritis drugs assessed by quantitative MRI in patients with knee osteoarthritis. Ann Rheum Dis 2010; 69: 2095-2101.
6. Roemer FW, Guermazi A, Felson DT, et al. Presence of MRIdetected joint effusion and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30-month follow-up: the MOST study. Ann Rheum Dis 2011; 70: 1804-1809.
7. Attur M, Krasnokutsky-Samuels S, Samuels J, Abramson SB. Prognostic biomarkers in osteoarthritis. Curr Opin Rheumatol 2013; 25: 136-144.
8. Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: a 26- year follow-up of participants in the Framingham Heart Study. Circulation 1983; 67: 968-977.
9. Lombard CB, Deeks AA, Teede HJ. A systematic review of interventions aimed at the prevention of weight gain in adults. Public Health Nutr 2009; 12: 2236-2246.
10. Messier SP, Mihalko SL, Legault C, et al. Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial. JAMA 2013; 310: 1263-1273.