Adenosinergic immunosuppression by human mesenchymal stromal cells requires co-operation with T cells

Stem Cells

Volumn 34, Issue 3, 2016, Pages 781-790

  Kerkelä, Erja ^a   Laitinen, Anita ^a   Räbinä, Jarkko ^a   Valkonen, Sami ^b   Takatalo, Maarit ^b   Larjo, Antti ^a   Veijola, Johanna ^c,d,e   Lampinen, Milla ^a   Siljander, Pia ^b   Lehenkari, Petri ^c,d,e   Alfthan, Kaija ^a   Laitinen, Saara ^a  

^a FINNISH RED CROSS BLOOD SERVICE   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c Institute of Clinical Medicine   (Finland)

^d UNIVERSITY OF OULU   (Finland)

^e OULU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Adenosine; CD73; Immunosuppression; Mesenchymal stromal cells; T cells

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CD39 ANTIGEN; APYRASE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; LEUKOCYTE ANTIGEN; NT5E PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; EXOSOME; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MESENCHYMAL STROMA CELL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; BIOSYNTHESIS; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM;

5'-NUCLEOTIDASE; ADENOSINE; ADENOSINE MONOPHOSPHATE; ANIMALS; ANTIGENS, CD; APYRASE; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; EXTRACELLULAR VESICLES; GPI-LINKED PROTEINS; HUMANS; IMMUNE TOLERANCE; IMMUNOSUPPRESSION; LYMPHOCYTE ACTIVATION; MESENCHYMAL STROMAL CELLS;

EID: 84956615274     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2280     Document Type: Article

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