Resting-state functional connectivity and presynaptic monoamine signaling in Alcohol Dependence

Human Brain Mapping

Volumn 36, Issue 12, 2015, Pages 4808-4818

  Zhu, Xi ^a   Dutta, Nisha ^a   Helton, Sarah G ^a   Schwandt, Melanie ^a   Yan, Jia ^a   Hodgkinson, Colin A ^a   Cortes, Carlos R ^a   Kerich, Mike ^a   Hall, Samuel ^a   Sun, Hui ^a   Phillips, Monte ^a   Momenan, Reza ^a   Lohoff, Falk W ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Genetics; Monoamine transporter; MPFC; Presynaptic; Resting state; SLC18A1

Indexed keywords

BRAIN MONOAMINE; ISOLEUCINE; THREONINE; VESICULAR MONOAMINE TRANSPORTER 1; OXYGEN; SLC18A1 PROTEIN, HUMAN; VESICULAR MONOAMINE TRANSPORTER;

ADULT; ALCOHOL DEPENDENCE SCALE; ALCOHOLISM; ALLELE; AMYGDALOID NUCLEUS; ANTERIOR CINGULATE; ARTICLE; BRAIN FUNCTION; BRAIN MAPPING; CONNECTOME; CONTROLLED STUDY; DEFAULT MODE NETWORK; DEMOGRAPHY; DISEASE PREDISPOSITION; EXECUTIVE FUNCTION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; HUMAN; INFERIOR FRONTAL GYRUS; KERNEL METHOD; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE ASSESSMENT; MIDDLE FRONTAL GYRUS; NUCLEAR MAGNETIC RESONANCE SCANNER; PREFRONTAL CORTEX; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; QUESTIONNAIRE; RESTING STATE NETWORK; SALIENCE NETWORK; SIGNAL TRANSDUCTION; STRUCTURED CLINICAL INTERVIEW FOR DSM DISORDERS; BIOLOGICAL MODEL; BLOOD; BRAIN; GENETICS; IMAGE PROCESSING; METABOLISM; MIDDLE AGED; MUTATION; NERVE TRACT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PRINCIPAL COMPONENT ANALYSIS; PSYCHOLOGICAL RATING SCALE; REST; VASCULARIZATION;

ADULT; ALCOHOLISM; BRAIN; FEMALE; GENOTYPE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MODELS, NEUROLOGICAL; MUTATION; NEURAL PATHWAYS; OXYGEN; PRINCIPAL COMPONENT ANALYSIS; PSYCHIATRIC STATUS RATING SCALES; REST; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 84956596946     PISSN: 10659471     EISSN: 10970193     Source Type: Journal    
DOI: 10.1002/hbm.22951     Document Type: Article

References (53)

1. Association AP (2013): Diagnostic and Statistical Manual of Mental Disorders, 5th ed. Washington, DC: American Psychiatric Association.
2. Becker HC, Mulholland PJ (2014): Neurochemical mechanisms of alcohol withdrawal. Handbook Clin Neurol 125:133-156.
3. Beckmann CF, DeLuca M, Devlin JT, Smith SM (2005): Investigations into resting-state connectivity using independent component analysis. Philos Trans R Soc Lond B Biol Sci 360:1001-1013.
4. Beckmann CF, Smith SM (2004): Probabilistic independent component analysis for functional magnetic resonance imaging. IEEE Trans Med Imaging 23:137-152.
5. Biswal B, Yetkin FZ, Haughton VM, Hyde JS (1995): Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 34:537-541.
6. Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe S, Dogonowski AM, Ernst M, Fair D, Hampson M, Hoptman MJ, Hyde JS, Kiviniemi VJ, Kotter R, Li SJ, Lin CP, Lowe MJ, Mackay C, Madden DJ, Madsen KH, Margulies DS, Mayberg HS, McMahon K, Monk CS, Mostofsky SH, Nagel BJ, Pekar JJ, Peltier SJ, Petersen SE, Riedl V, Rombouts SA, Rypma B, Schlaggar BL, Schmidt S, Seidler RD, Siegle GJ, Sorg C, Teng GJ, Veijola J, Villringer A, Walter M, Wang L, Weng XC, Whitfield-Gabrieli S, Williamson P, Windischberger C, Zang YF, Zhang HY, Castellanos FX, Milham MP (2010): Toward discovery science of human brain function. Proc Natl Acad Sci USA 107:4734-4739.
7. Bly M (2005): Mutation in the vesicular monoamine gene, SLC18A1, associated with schizophrenia. Schizophr Res 78:337-338.
8. Camchong J, Stenger A, Fein G (2013a): Resting-state synchrony during early alcohol abstinence can predict subsequent relapse. Cereb Cortex 23:2086-2099.
9. Camchong J, Stenger A, Fein G (2013b): Resting-state synchrony in long-term abstinent alcoholics. Alcohol, Clin Exp Res 37:75-85.
10. Chanraud S, Pitel AL, Pfefferbaum A, Sullivan EV (2011): Disruption of functional connectivity of the default-mode network in alcoholism. Cereb Cortex 21:2272-2281.
11. Charlet K, Beck A, Heinz A (2013): The dopamine system in mediating alcohol effects in humans. Curr Topic Behav Neurosci 13:461-488.
12. Chen SF, Chen CH, Chen JY, Wang YC, Lai IC, Liou YJ, Liao DL (2007): Support for association of the A277C single nucleotide polymorphism in human vesicular monoamine transporter 1 gene with schizophrenia. Schizophr Res 90:363-365.
13. Cole DM, Smith SM, Beckmann CF (2010): Advances and pitfalls in the analysis and interpretation of resting-state FMRI data. Front Syst Neurosci 4:8
14. Courtney KE, Ghahremani DG, Ray LA (2013): Fronto-striatal functional connectivity during response inhibition in alcohol dependence. Addict Biol 18:593-604.
15. Dager AD, Anderson BM, Stevens MC, Pulido C, Rosen R, Jiantonio-Kelly RE, Sisante JF, Raskin SA, Tennen H, Austad CS, Wood RM, Fallahi CR, Pearlson GD (2013): Influence of alcohol use and family history of alcoholism on neural response to alcohol cues in college drinkers. Alcohol Clin Exp Res 37(Suppl 1):E161-E171.
16. Durkee CA, Sarlls JE, Hommer DW, Momenan R (2013): White matter microstructure alterations: A study of alcoholics with and without post-traumatic stress disorder. PLoS One 8:e80952.
17. Fehr C, Sommerlad D, Sander T, Anghelescu I, Dahmen N, Szegedi A, Mueller C, Zill P, Soyka M, Preuss UW (2013): Association of VMAT2 gene polymorphisms with alcohol dependence. J Neural Transm 120:1161-1169.
18. First M, Spitzer RL, Gibbon M, Williams J. (1996) Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Clinician Version. Washington, DC: American Psychiatric Press.
19. Fon EA, Pothos EN, Sun BC, Killeen N, Sulzer D, Edwards RH (1997): Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron 19:1271-1283.
20. Fujimoto A, Nagao T, Ebara T, Sato M, Otsuki S (1983): Cerebrospinal fluid monoamine metabolites during alcohol withdrawal syndrome and recovered state. Biol Psychiatry 18:1141-1152.
21. Grodin EN, Lin H, Durkee CA, Hommer DW, Momenan R (2013): Deficits in cortical, diencephalic and midbrain gray matter in alcoholism measured by VBM: Effects of co-morbid substance abuse. NeuroImage Clin 2:469-476.
22. Hansson SR, Hoffman BJ, Mezey E (1998): Ontogeny of vesicular monoamine transporter mRNAs VMAT1 and VMAT2. I. The developing rat central nervous system. Brain Res Dev Brain Res 110:135-158.
23. Hodgkinson CA, Yuan Q, Xu K, Shen PH, Heinz E, Lobos EA, Binder EB, Cubells J, Ehlers CL, Gelernter J, Mann J, Riley B, Roy A, Tabakoff B, Todd RD, Zhou Z, Goldman D (2008): Addictions biology: Haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol 43:505-515.
24. Hyvarinen A (1999): Fast and robust fixed-point algorithms for independent component analysis. IEEE Trans Neural Network 10:626-634.
25. Jansen JM, van Holst RJ, van den Brink W, Veltman DJ, Caan MW, Goudriaan AE (2015): Brain function during cognitive flexibility and white matter integrity in alcohol-dependent patients, problematic drinkers and healthy controls. Addict Biol 20:979-989.
26. Jenkinson M, Bannister P, Brady M, Smith S (2002): Improved optimization for the robust and accurate linear registration and motion correction of brain images. NeuroImage 17:825-841.
27. Jenkinson M, Smith S (2001): A global optimisation method for robust affine registration of brain images. Med Image Anal 5:143-156.
28. Koob GF, Le Moal M (2001): Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24:97-129.
29. Krmpotich TD, Tregellas JR, Thompson LL, Banich MT, Klenk AM, Tanabe JL (2013): Resting-state activity in the left executive control network is associated with behavioral approach and is increased in substance dependence. Drug Alcohol Depend 129:1-7.
30. Lin Z, Walther D, Yu XY, Li S, Drgon T, Uhl GR (2005): SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism. Hum Mol Genet 14:1393-1404.
31. Lohoff FW, Dahl JP, Ferraro TN, Arnold SE, Gallinat J, Sander T, Berrettini WH (2006): Variations in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) are associated with bipolar i disorder. Neuropsychopharmacology 31:2739-2747.
32. Lohoff FW, Lautenschlager M, Mohr J, Ferraro TN, Sander T, Gallinat J (2008a): Association between variation in the vesicular monoamine transporter 1 gene on chromosome 8p and anxiety-related personality traits. Neurosci Lett 434:41-45.
33. Lohoff FW, Weller AE, Bloch PJ, Buono RJ, Doyle GA, Ferraro TN, Berrettini WH (2008b): Association between polymorphisms in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) on chromosome 8p and schizophrenia. Neuropsychobiology 57:55-60.
34. Lohoff FW, Hodge R, Narasimhan S, Nall A, Ferraro TN, Mickey BJ, Heitzeg MM, Langenecker SA, Zubieta JK, Bogdan R, Nikolova YS, Drabant E, Hariri AR, Bevilacqua L, Goldman D, Doyle GA (2014): Functional genetic variants in the vesicular monoamine transporter 1 modulate emotion processing. Mol Psychiatry 19:129-139.
35. Ma N, Liu Y, Li N, Wang CX, Zhang H, Jiang XF, Xu HS, Fu XM, Hu X, Zhang DR (2010): Addiction related alteration in resting-state brain connectivity. NeuroImage 49:738-744.
36. Momenan R, Steckler LE, Saad ZS, van Rafelghem S, Kerich MJ, Hommer DW (2012): Effects of alcohol dependence on cortical thickness as determined by magnetic resonance imaging. Psychiatry Res 204:101-111.
37. Muller-Oehring EM, Jung YC, Pfefferbaum A, Sullivan EV, Schulte T (2014): The Resting Brain of Alcoholics. Cereb Cortex doi: 10.1093/cercor/bhu134
38. Multani PK, Hodge R, Estevez MA, Abel T, Kung H, Alter M, Brookshire B, Lucki I, Nall AH, Talbot K, Doyle GA, Lohoff FW (2012): VMAT1 deletion causes neuronal loss in the hippocampus and neurocognitive deficits in spatial discrimination. Neuroscience 232C:32-44.
39. Need AC, Keefe RS, Ge D, Grossman I, Dickson S, McEvoy JP, Goldstein DB (2009): Pharmacogenetics of antipsychotic response in the CATIE trial: A candidate gene analysis. Eur J Hum Genet 17:946-957.
40. Orban C, McGonigle J, Kalk NJ, Erritzoe D, Waldman AD, Nutt DJ, Rabiner EA, Lingford-Hughes AR (2013): Resting state synchrony in anxiety-related circuits of abstinent alcohol-dependent patients. Am J Drug Alcohol Abuse 39:433-440.
41. Pfefferbaum A, Rosenbloom MJ, Adalsteinsson E, Sullivan EV (2007): Diffusion tensor imaging with quantitative fibre tracking in HIV infection and alcoholism comorbidity: Synergistic white matter damage. Brain 130:48-64.
42. Rogers BP, Parks MH, Nickel MK, Katwal SB, Martin PR (2012): Reduced fronto-cerebellar functional connectivity in chronic alcoholic patients. Alcohol Clin Exp Res 36:294-301.
43. Schwab SG, Franke PE, Hoefgen B, Guttenthaler V, Lichtermann D, Trixler M, Knapp M, Maier W, Wildenauer DB (2005): Association of DNA polymorphisms in the synaptic vesicular amine transporter gene (SLC18A2) with alcohol and nicotine dependence. Neuropsychopharmacology: Official publication of the American College of. Neuropsychopharmacology 30:2263-2268.
44. Seo D, Lacadie CM, Tuit K, Hong KI, Constable RT, Sinha R (2013): Disrupted ventromedial prefrontal function, alcohol craving, and subsequent relapse risk. JAMA Psychiatry 70:727-739.
45. Smith SM (2002): Fast robust automated brain extraction. Hum Brain Mapp 17:143-155.
46. Stahre M, Roeber J, Kanny D, Brewer RD, Zhang X (2014): Contribution of excessive alcohol consumption to deaths and years of potential life lost in the United States. Prevent Chronic Dis 11:E109
47. Takahashi N, Uhl G (1997): Murine vesicular monoamine transporter 2: Molecular cloning and genomic structure. Brain Res Mol Brain Res 49:7-14.
48. van den Heuvel MP, Mandl RC, Kahn RS, Hulshoff Pol HE (2009): Functionally linked resting-state networks reflect the underlying structural connectivity architecture of the human brain. Hum Brain Mapp 30:3127-3141.
49. Wang YM, Gainetdinov RR, Fumagalli F, Xu F, Jones SR, Bock CB, Miller GW, Wightman RM, Caron MG (1997): Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron 19:1285-1296.
50. Weiland BJ, Sabbineni A, Calhoun VD, Welsh RC, Bryan AD, Jung RE, Mayer AR, Hutchison KE (2014): Reduced left executive control network functional connectivity is associated with alcohol use disorders. Alcohol Clin Exp Res 38:2445-2453.
51. Yang X, Zhang H, Lai J (2014): [Alcohol dependence mediated by monoamine neurotransmitters in the central nervous system]. Yi Chuan 36:11-20.
52. Zhu X, Cortes C, Mathur K, Tomasi D, Momenan R (2015): Model-free functional connectivity and impulsivity correlates of alcohol dependence: A resting-state study. Addict Biol doi: 10.1111/adb.12272
53. Zuo XN, Kelly C, Adelstein JS, Klein DF, Castellanos FX, Milham MP (2010): Reliable intrinsic connectivity networks: Test-retest evaluation using ICA and dual regression approach. NeuroImage 49:2163-2177.