Mycobacteria infect different cell types in the human lung and cause species dependent cellular changes in infected cells

BMC Pulmonary Medicine

Volumn 16, Issue 1, 2016, Pages

  Ganbat, Dariimaa ^a,b   Seehase, Sophie ^a,c   Richter, Elvira ^a,e   Vollmer, Ekkehard ^a,c   Reiling, Norbert ^a   Fellenberg, Kurt ^a   Gaede, Karoline I ^a,c   Kugler, Christian ^c,d   Goldmann, Torsten ^a,c  

^a RESEARCH CENTER BORSTEL   (Germany)

^b MONGOLIAN NATIONAL UNIVERSITY OF MEDICAL SCIENCES   (Mongolia)

^c German Center for Lung Research   (Germany)

^d LungenClinic Grosshansdorf   (Germany)

^e Labor Limbach   (Germany)

Author keywords

Cellular change; Ex vivo; HOPE fixation; Innate immunity; Intracellular infection; M. abscessus; M. avium; M. tuberculosis; Mycobacteria; STST model; Tissue viability; Tuberculosis

Indexed keywords

BACTERIAL DNA; NUCLEIC ACID;

ARTICLE; BACTERIAL STRAIN; CELL DAMAGE; CELL DEATH; CELL POPULATION; CONTROLLED STUDY; DNA DETERMINATION; EX VIVO STUDY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL; LUNG PARENCHYMA; MACROPHAGE; MICROENVIRONMENT; MONOCYTE; MYCOBACTERIOSIS; MYCOBACTERIUM ABSCESSUS; MYCOBACTERIUM AVIUM; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL; POLYMERASE CHAIN REACTION; SPECIES DIFFERENCE; TISSUE CULTURE; TUNEL ASSAY; ATYPICAL MYCOBACTERIOSIS; CELL NUCLEUS; GENETICS; IN VITRO STUDY; LUNG; LUNG ALVEOLUS EPITHELIUM CELL; LUNG ALVEOLUS MACROPHAGE; LUNG TUBERCULOSIS; LYMPHOCYTE; METABOLISM; MICROBIOLOGY; MYCOBACTERIUM; PATHOLOGY; TISSUE CULTURE TECHNIQUE; TISSUE SURVIVAL;

ALVEOLAR EPITHELIAL CELLS; CELL NUCLEUS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; IN VITRO TECHNIQUES; LUNG; LYMPHOCYTES; MACROPHAGES, ALVEOLAR; MONOCYTES; MYCOBACTERIUM; MYCOBACTERIUM AVIUM; MYCOBACTERIUM INFECTIONS, NONTUBERCULOUS; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHILS; POLYMERASE CHAIN REACTION; TISSUE CULTURE TECHNIQUES; TISSUE SURVIVAL; TUBERCULOSIS, PULMONARY;

EID: 84956580657     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/s12890-016-0185-5     Document Type: Article

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