-
1
-
-
42549093749
-
Terpenoids: Opportunities for biosynthesis of natural product drugs using engineered microorganisms
-
Ajikumar PK, Tyo K, Carlsen S, Mucha O, Phon TH, Stephanopoulos G (2008) Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms. Mol Pharm 5:167-190
-
(2008)
Mol Pharm
, vol.5
, pp. 167-190
-
-
Ajikumar, P.K.1
Tyo, K.2
Carlsen, S.3
Mucha, O.4
Phon, T.H.5
Stephanopoulos, G.6
-
2
-
-
1942532925
-
Origins and evolution of isoprenoid lipid biosynthesis in archaea
-
Boucher Y, Kamekura M, Doolittle WF (2004) Origins and evolution of isoprenoid lipid biosynthesis in archaea. Mol Microbiol 52:515-527
-
(2004)
Mol Microbiol
, vol.52
, pp. 515-527
-
-
Boucher, Y.1
Kamekura, M.2
Doolittle, W.F.3
-
4
-
-
42549100536
-
Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake
-
Brown AC, Parish T (2008) Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake. BMC Microbiol 8:78
-
(2008)
BMC Microbiol
, vol.8
, pp. 78
-
-
Brown, A.C.1
Parish, T.2
-
5
-
-
33749548848
-
Prokaryotic photosynthesis and phototrophy illuminated
-
Bryant DA, Frigaard NU (2006) Prokaryotic photosynthesis and phototrophy illuminated. Trends Microbiol 14:488-496
-
(2006)
Trends Microbiol
, vol.14
, pp. 488-496
-
-
Bryant, D.A.1
Frigaard, N.U.2
-
6
-
-
33750487491
-
Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase
-
Carretero-Paulet L, Cairó A, Botella-Pavía P et al (2006) Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase. Plant Mol Biol 62:683-695
-
(2006)
Plant Mol Biol
, vol.62
, pp. 683-695
-
-
Carretero-Paulet, L.1
Cairó, A.2
Botella-Pavía, P.3
-
7
-
-
73449092883
-
Characterization of thermophilic archaeal isopentenyl phosphate kinases
-
Chen M, Poulter CD (2010) Characterization of thermophilic archaeal isopentenyl phosphate kinases. Biochemistry 49:207-217
-
(2010)
Biochemistry
, vol.49
, pp. 207-217
-
-
Chen, M.1
Poulter, C.D.2
-
8
-
-
15544389776
-
Studies on biosynthetic genes and enzymes of isoprenoids produced by actinomycetes
-
Tokyo
-
Dairi J (2005) Studies on biosynthetic genes and enzymes of isoprenoids produced by actinomycetes. J Antibiot (Tokyo) 58:227-243
-
(2005)
J Antibiot
, vol.58
, pp. 227-243
-
-
Dairi, J.1
-
9
-
-
36249014291
-
An update on microbial carotenoid production: Application of recent metabolic engineering tools
-
Das A, Yoon SH, Lee SH, Kim JY, Oh DK, Kim SW (2007) An update on microbial carotenoid production: application of recent metabolic engineering tools. Appl Microbiol Biotechnol 77:505-512
-
(2007)
Appl Microbiol Biotechnol
, vol.77
, pp. 505-512
-
-
Das, A.1
Yoon, S.H.2
Lee, S.H.3
Kim, J.Y.4
Oh, D.K.5
Kim, S.W.6
-
10
-
-
50849124455
-
Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate
-
de Ruyck J, Pouyez J, Rothman SC, Poulter D, Wouters J (2008) Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate. Biochemistry 47:9051-9053
-
(2008)
Biochemistry
, vol.47
, pp. 9051-9053
-
-
De Ruyck, J.1
Pouyez, J.2
Rothman, S.C.3
Poulter, D.4
Wouters, J.5
-
11
-
-
28844484972
-
1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis: Towards understanding mycobacterial resistance to fosmidomycin
-
Dhiman RK, Schaeffer ML, Bailey AM, Testa CA, Scherman H, Crick DC (2005) 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis: towards understanding mycobacterial resistance to fosmidomycin. J Bacteriol 187:8395-8402
-
(2005)
J Bacteriol
, vol.187
, pp. 8395-8402
-
-
Dhiman, R.K.1
Schaeffer, M.L.2
Bailey, A.M.3
Testa, C.A.4
Scherman, H.5
Crick, D.C.6
-
12
-
-
17744398410
-
Crystal structure of isopentenyl diphosphate:Dimethylallyl diphosphate isomerase
-
Durbecq V, Sainz G, Oudjama Y et al (2001) Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase. EMBO J 20:1530-1537
-
(2001)
EMBO J
, vol.20
, pp. 1530-1537
-
-
Durbecq, V.1
Sainz, G.2
Oudjama, Y.3
-
15
-
-
0030579174
-
Cloning of a gene from Escherichia coli that confers resistance to fosmidomycin as a consequence of amplification
-
Fujisaki S, Ohnuma S, Horiuchi T et al (1996) Cloning of a gene from Escherichia coli that confers resistance to fosmidomycin as a consequence of amplification. Gene 175:83-87
-
(1996)
Gene
, vol.175
, pp. 83-87
-
-
Fujisaki, S.1
Ohnuma, S.2
Horiuchi, T.3
-
16
-
-
34548512297
-
Chlorophyll biosynthesis in bacteria: The origins of structural and functional diversity
-
Gomez Maqueo Chew A, Bryant DA (2007) Chlorophyll biosynthesis in bacteria: the origins of structural and functional diversity. Annu Rev Microbiol 61:113-129
-
(2007)
Annu Rev Microbiol
, vol.61
, pp. 113-129
-
-
Gomez Maqueo Chew, A.1
Bryant, D.A.2
-
17
-
-
33646238682
-
Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate
-
Grochowski LL, Xu H, White RH (2006) Methanocaldococcus jannaschii uses a modified mevalonate pathway for biosynthesis of isopentenyl diphosphate. J Bacteriol 188:3192-3198
-
(2006)
J Bacteriol
, vol.188
, pp. 3192-3198
-
-
Grochowski, L.L.1
Xu, H.2
White, R.H.3
-
18
-
-
0032811818
-
Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase
-
Hahn FM, Hurlburt AP, Poulter CD (1999) Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase. J Bacteriol 181:4499-4504
-
(1999)
J Bacteriol
, vol.181
, pp. 4499-4504
-
-
Hahn, F.M.1
Hurlburt, A.P.2
Poulter, C.D.3
-
19
-
-
33750048147
-
A cytosolic Arabidopsis D-xylulose kinase catalyzes the phosphorylation of 1-deoxy-D-xylulose into a precursor of the plastidial isoprenoid pathway
-
Hemmerlin A, Tritsch D, Hartmann M et al (2006) A cytosolic Arabidopsis D-xylulose kinase catalyzes the phosphorylation of 1-deoxy-D-xylulose into a precursor of the plastidial isoprenoid pathway. Plant Physiol 142:441-457
-
(2006)
Plant Physiol
, vol.142
, pp. 441-457
-
-
Hemmerlin, A.1
Tritsch, D.2
Hartmann, M.3
-
20
-
-
34547609909
-
The non-mevalonate pathway of iso-prenoid precursor biosynthesis
-
Hunter WN (2007) The non-mevalonate pathway of iso-prenoid precursor biosynthesis. J Biol Chem 282:21573-21577
-
(2007)
J Biol Chem
, vol.282
, pp. 21573-21577
-
-
Hunter, W.N.1
-
21
-
-
0033520336
-
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs
-
Jomaa H, Wiesner J, Sanderbrand S et al (1999) Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science 285:1573-1576
-
(1999)
Science
, vol.285
, pp. 1573-1576
-
-
Jomaa, H.1
Wiesner, J.2
Sanderbrand, S.3
-
22
-
-
0035970116
-
An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. Strain CL190
-
Kaneda K, Kuzuyama T, Takagi M, Hayakawa Y, Seto H (2001) An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190. Proc Natl Acad Sci USA 98:932-937
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 932-937
-
-
Kaneda, K.1
Kuzuyama, T.2
Takagi, M.3
Hayakawa, Y.4
Seto, H.5
-
23
-
-
0032943554
-
Hopanoid biosynthesis and function in bacteria
-
Kannenberg EL, Poralla K (1999) Hopanoid biosynthesis and function in bacteria. Naturwissenschaften 86: 168-176
-
(1999)
Naturwissenschaften
, vol.86
, pp. 168-176
-
-
Kannenberg, E.L.1
Poralla, K.2
-
24
-
-
0036965887
-
Biosynthesis, bioproduction and novel roles of ubiquinone
-
Kawamukai M (2002) Biosynthesis, bioproduction and novel roles of ubiquinone. J Biosci Bioeng 94: 511-517
-
(2002)
J Biosci Bioeng
, vol.94
, pp. 511-517
-
-
Kawamukai, M.1
-
25
-
-
48149106189
-
Metabolic engineering of microorganisms for isoprenoid production
-
Kirby J, Keasling JD (2008) Metabolic engineering of microorganisms for isoprenoid production. Nat Prod Rep 25:656-661
-
(2008)
Nat Prod Rep
, vol.25
, pp. 656-661
-
-
Kirby, J.1
Keasling, J.D.2
-
26
-
-
67651030513
-
Biosynthesis of plant isoprenoids: Perspectives for microbial engineering
-
Kirby J, Keasling JD (2009) Biosynthesis of plant isoprenoids: perspectives for microbial engineering. Annu Rev Plant Biol 60:335-355.
-
(2009)
Annu Rev Plant Biol
, vol.60
, pp. 335-355
-
-
Kirby, J.1
Keasling, J.D.2
-
27
-
-
35548954677
-
Engineering microbial cell factories for biosynthesis of isoprenoid molecules: Beyond lycopene
-
Klein-Marcuschamer D, Ajikumar PK, Stephanopoulos G (2007) Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene. Trends Biotechnol 25:417-424
-
(2007)
Trends Biotechnol
, vol.25
, pp. 417-424
-
-
Klein-Marcuschamer, D.1
Ajikumar, P.K.2
Stephanopoulos, G.3
-
28
-
-
33947425547
-
Biosynthesis of ether-type polar lipids in archaea and evolutionary considerations
-
Koga Y, Morii H (2007) Biosynthesis of ether-type polar lipids in archaea and evolutionary considerations. Microbiol Mol Biol Rev 71:97-120
-
(2007)
Microbiol Mol Biol Rev
, vol.71
, pp. 97-120
-
-
Koga, Y.1
Morii, H.2
-
29
-
-
14244257854
-
Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: Phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reductoisomerase
-
Kuntz L, Tritsch D, Grosdemange-Billiard C et al (2005) Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reductoisomerase. Biochem J 386:127-135
-
(2005)
Biochem J
, vol.386
, pp. 127-135
-
-
Kuntz, L.1
Tritsch, D.2
Grosdemange-Billiard, C.3
-
30
-
-
0037394552
-
Diversity of the biosynthesis of the isoprene units
-
Kuzuyama T, Seto H (2003) Diversity of the biosynthesis of the isoprene units. Nat Prod Rep 20:171-183
-
(2003)
Nat Prod Rep
, vol.20
, pp. 171-183
-
-
Kuzuyama, T.1
Seto, H.2
-
31
-
-
0032558613
-
Fosmidomycin, a specific inhibitor of 1-deoxy-D-xy-lulose 5-phosphate reductoisomerase in the nonme-valonate pathway for terpenoid biosynthesis
-
Kuzuyama T, Shimizu T, Takahashi S, Seto H (1998) Fosmidomycin, a specific inhibitor of 1-deoxy-D-xy-lulose 5-phosphate reductoisomerase in the nonme-valonate pathway for terpenoid biosynthesis. Tetrahedron Lett 39:7913-7916
-
(1998)
Tetrahedron Lett
, vol.39
, pp. 7913-7916
-
-
Kuzuyama, T.1
Shimizu, T.2
Takahashi, S.3
Seto, H.4
-
32
-
-
0034700150
-
Isoprenoid biosynthesis: The evolution of two ancient and distinct pathways across genomes
-
Lange BM, Rujan T, Martin W, Croteau R (2000) Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes. Proc Natl Acad Sci USA 97:13172-13177
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13172-13177
-
-
Lange, B.M.1
Rujan, T.2
Martin, W.3
Croteau, R.4
-
33
-
-
0034830836
-
Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis
-
Lange BM, Ketchum RE, Croteau RB (2001) Isoprenoid biosynthesis. Metabolite profiling of peppermint oil gland secretory cells and application to herbicide target analysis. Plant Physiol 127:305-314
-
(2001)
Plant Physiol
, vol.127
, pp. 305-314
-
-
Lange, B.M.1
Ketchum, R.E.2
Croteau, R.B.3
-
34
-
-
3042767995
-
Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways
-
Laupitz R, Hecht S, Amslinger S et al (2004) Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. Eur J Biochem 271:2658-2669
-
(2004)
Eur J Biochem
, vol.271
, pp. 2658-2669
-
-
Laupitz, R.1
Hecht, S.2
Amslinger, S.3
-
35
-
-
0037209731
-
Metabolic engineering towards biotechnological production of carotenoids in microorganisms
-
Lee PC, Schmidt-Dannert C (2002) Metabolic engineering towards biotechnological production of carotenoids in microorganisms. Appl Microbiol Biotechnol 60:1-11
-
(2002)
Appl Microbiol Biotechnol
, vol.60
, pp. 1-11
-
-
Lee, P.C.1
Schmidt-Dannert, C.2
-
36
-
-
0033513375
-
The 1-deoxy-D-xylulose-5-phosphate pathway of isoprenoid biosynthesis in plants
-
Lichtenthaler HK (1999) The 1-deoxy-D-xylulose-5-phosphate pathway of isoprenoid biosynthesis in plants. Annu Rev Plant Physiol Plant Mol Biol 50:47-65
-
(1999)
Annu Rev Plant Physiol Plant Mol Biol
, vol.50
, pp. 47-65
-
-
Lichtenthaler, H.K.1
-
37
-
-
78650467548
-
Origins and early evolution of the mevalonate pathway of isoprenoid biosynthesis in the three domains of life
-
Lombard J, Moreira D (2011) Origins and early evolution of the mevalonate pathway of isoprenoid biosynthesis in the three domains of life. Mol Biol Evol 28:87-99
-
(2011)
Mol Biol Evol
, vol.28
, pp. 87-99
-
-
Lombard, J.1
Moreira, D.2
-
38
-
-
77952843076
-
X-ray structures of isopentenyl phosphate kinase
-
Mabanglo MF, Schubert HL, Chen M, Hill CP, Poulter CD (2010) X-ray structures of isopentenyl phosphate kinase. ACS Chem Biol 5:517-527
-
(2010)
ACS Chem Biol
, vol.5
, pp. 517-527
-
-
Mabanglo, M.F.1
Schubert, H.L.2
Chen, M.3
Hill, C.P.4
Poulter, C.D.5
-
39
-
-
48349136893
-
The biochemical basis for structural diversity in the carotenoids of chlorophototrophic bacteria
-
Maresca JA, Graham JE, Bryant DA (2008) The biochemical basis for structural diversity in the carotenoids of chlorophototrophic bacteria. Photosynth Res 97: 121-140
-
(2008)
Photosynth Res
, vol.97
, pp. 121-140
-
-
Maresca, J.A.1
Graham, J.E.2
Bryant, D.A.3
-
40
-
-
78049310358
-
The herbicide ketoclomazone inhibits 1-deoxy-D-xylulose 5-phosphate synthase in the 2-C-methyl-D-erythritol 4-phosphate pathway and shows antibacterial activity against Haemophilus influenzae
-
Matsue Y, Mizuno H, Tomita T et al (2010) The herbicide ketoclomazone inhibits 1-deoxy-D-xylulose 5-phosphate synthase in the 2-C-methyl-D-erythritol 4-phosphate pathway and shows antibacterial activity against Haemophilus influenzae. J Antibiot (Tokyo) 63: 583-588
-
(2010)
J Antibiot (Tokyo)
, vol.63
, pp. 583-588
-
-
Matsue, Y.1
Mizuno, H.2
Tomita, T.3
-
41
-
-
0035949539
-
Ubiquinone biosynthesis in microorganisms
-
Meganathan R (2001) Ubiquinone biosynthesis in microorganisms. FEMS Microbiol Lett 203:131-139
-
(2001)
FEMS Microbiol Lett
, vol.203
, pp. 131-139
-
-
Meganathan, R.1
-
42
-
-
79957636478
-
Pathway engineering for functional isoprenoids
-
Misawa N (2011) Pathway engineering for functional isoprenoids. Curr Opin Biotechnol 22:1-7
-
(2011)
Curr Opin Biotechnol
, vol.22
, pp. 1-7
-
-
Misawa, N.1
-
43
-
-
0028152645
-
Biosynthesis and functional role of haem O and haem A
-
Mogi T, Saiki K, Anraku Y (1994) Biosynthesis and functional role of haem O and haem A. Mol Microbiol 14:391-398
-
(1994)
Mol Microbiol
, vol.14
, pp. 391-398
-
-
Mogi, T.1
Saiki, K.2
Anraku, Y.3
-
44
-
-
0034472991
-
Properties and inhibition of the first two enzymes of the non-mevalonate pathway of isoprenoid biosynthesis
-
Müller C, Schwender J, Zeidler J, Lichtenthaler HK (2000) Properties and inhibition of the first two enzymes of the non-mevalonate pathway of isoprenoid biosynthesis. Biochem Soc Trans 28:792-793
-
(2000)
Biochem Soc Trans
, vol.28
, pp. 792-793
-
-
Müller, C.1
Schwender, J.2
Zeidler, J.3
Lichtenthaler, H.K.4
-
45
-
-
79952799494
-
The methylerythritol phosphate (MEP) pathway for iso-prenoid biosynthesis as a target for the development of new drugs against tuberculosis
-
Obiol-Pardo C, Rubio-Martinez J, Imperial S (2011) The methylerythritol phosphate (MEP) pathway for iso-prenoid biosynthesis as a target for the development of new drugs against tuberculosis. Curr Med Chem 18:1325-1338
-
(2011)
Curr Med Chem
, vol.18
, pp. 1325-1338
-
-
Obiol-Pardo, C.1
Rubio-Martinez, J.2
Imperial, S.3
-
46
-
-
0019252768
-
Studies on new phosphonic acid antibiotics. Iii. Isolation and characterization of FR-31564, FR-32863 and FR-33289
-
Tokyo
-
Okuhara M, Kuroda Y, Goto T et al (1980) Studies on new phosphonic acid antibiotics. III. Isolation and characterization of FR-31564, FR-32863 and FR-33289. J Antibiot (Tokyo) 33:24-28
-
(1980)
J Antibiot
, vol.33
, pp. 24-28
-
-
Okuhara, M.1
Kuroda, Y.2
Goto, T.3
-
47
-
-
0028609454
-
Synthesis and function of isopentenyl adenosine derivatives in tRNA
-
Persson BC, Esberg B, Olafsson O, Bjork GR (1994) Synthesis and function of isopentenyl adenosine derivatives in tRNA. Biochimie 76:1152-1160
-
(1994)
Biochimie
, vol.76
, pp. 1152-1160
-
-
Persson, B.C.1
Esberg, B.2
Olafsson, O.3
Bjork, G.R.4
-
49
-
-
3042782938
-
The MEP pathway: A new target for the development of herbicides, antibiotics and antimalarial drugs
-
Rodríguez-Concepción M (2004) The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs. Curr Pharm Des 10: 2391-2400
-
(2004)
Curr Pharm Des
, vol.10
, pp. 2391-2400
-
-
Rodríguez-Concepción, M.1
-
50
-
-
0036851226
-
Elucidation of the methylerythritol phosphate pathway for iso-prenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomic
-
Rodríguez-Concepción M, Boronat A (2002) Elucidation of the methylerythritol phosphate pathway for iso-prenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomic. Plant Physiol 130:1079-1089
-
(2002)
Plant Physiol
, vol.130
, pp. 1079-1089
-
-
Rodríguez-Concepción, M.1
Boronat, A.2
-
51
-
-
0034685844
-
Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli
-
Rodríguez-Concepción M, Campos N, Lois ML et al (2000) Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. FEBS Lett 473:328-332
-
(2000)
FEBS Lett
, vol.473
, pp. 328-332
-
-
Rodríguez-Concepción, M.1
Campos, N.2
Lois, M.L.3
-
52
-
-
0033213706
-
The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants
-
Rohmer M (1999) The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants. Nat Prod Rep 16:565-574
-
(1999)
Nat Prod Rep
, vol.16
, pp. 565-574
-
-
Rohmer, M.1
-
53
-
-
57149136899
-
From molecular fossils of bacterial hopanoids to the formation of isoprene units: Discovery and elucidation of the methylerythritol phosphate pathway
-
Rohmer M (2008) From molecular fossils of bacterial hopanoids to the formation of isoprene units: discovery and elucidation of the methylerythritol phosphate pathway. Lipids 43:1095-1107
-
(2008)
Lipids
, vol.43
, pp. 1095-1107
-
-
Rohmer, M.1
-
55
-
-
41849091915
-
Type II isopentenyl diphosphate isomerase: Irreversible inactivation by covalent modification of flavin
-
Rothman SC, Johnston JB, Lee S, Walker JR, Poulter CD (2008) Type II isopentenyl diphosphate isomerase: irreversible inactivation by covalent modification of flavin. J Am Chem Soc 130:4906-4913
-
(2008)
J am Chem Soc
, vol.130
, pp. 4906-4913
-
-
Rothman, S.C.1
Johnston, J.B.2
Lee, S.3
Walker, J.R.4
Poulter, C.D.5
-
56
-
-
2842613801
-
Fosmidomycin resistance in adenylate cyclase deficient (Cya) mutants of Escherichia coli
-
Sakamoto Y, Furukawa S, Ogihara H, Yamasaki M (2003) Fosmidomycin resistance in adenylate cyclase deficient (cya) mutants of Escherichia coli. Biosci Biotechnol Biochem 67:2030-2033
-
(2003)
Biosci Biotechnol Biochem
, vol.67
, pp. 2030-2033
-
-
Sakamoto, Y.1
Furukawa, S.2
Ogihara, H.3
Yamasaki, M.4
-
57
-
-
77956282463
-
A new family of enzymes catalyzing the first committed step of the methylerythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in bacteria
-
Sangari FJ, Pérez-Gil J, Carretero-Paulet L, García-Lobo JM, Rodríguez-Concepción M (2010) A new family of enzymes catalyzing the first committed step of the methylerythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in bacteria. Proc Natl Acad Sci USA 107:14081-14086
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14081-14086
-
-
Sangari, F.J.1
Pérez-Gil, J.2
Carretero-Paulet, L.3
García-Lobo, J.M.4
Rodríguez-Concepción, M.5
-
58
-
-
0037675908
-
Identification of lethal mutations in Escherichia coli genes encoding enzymes of the methylerythritol phosphate pathway
-
Sauret-Güeto S, Ramos-Valdivia A, Ibáñez E, Boronat A, Rodríguez-Concepción M (2003) Identification of lethal mutations in Escherichia coli genes encoding enzymes of the methylerythritol phosphate pathway. Biochem Biophys Res Commun 307:408-415
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 408-415
-
-
Sauret-Güeto, S.1
Ramos-Valdivia, A.2
Ibáñez, E.3
Boronat, A.4
Rodríguez-Concepción, M.5
-
59
-
-
31444432723
-
A mutant pyruvate dehydrogenase E1 subunit allows survival of Escherichia coli strains defective in 1-deoxy-D-xylu-lose 5-phosphate synthase
-
Sauret-Güeto S, Urós EM, Ibáñez E, Boronat A, Rodríguez Concepción M (2006) A mutant pyruvate dehydrogenase E1 subunit allows survival of Escherichia coli strains defective in 1-deoxy-D-xylu-lose 5-phosphate synthase. FEBS Lett 580:736-740
-
(2006)
FEBS Lett
, vol.580
, pp. 736-740
-
-
Sauret-Güeto, S.1
Urós, E.M.2
Ibáñez, E.3
Boronat, A.4
Rodríguez Concepción, M.5
-
60
-
-
77954820591
-
Type II isopente-nyl diphosphate isomerase: Probing the mechanism with alkyne/allene diphosphate substrate analogues
-
Sharma NK, Pan JJ, Poulter CD (2010) Type II isopente-nyl diphosphate isomerase: probing the mechanism with alkyne/allene diphosphate substrate analogues. Biochemistry 49:6228-6233
-
(2010)
Biochemistry
, vol.49
, pp. 6228-6233
-
-
Sharma, N.K.1
Pan, J.J.2
Poulter, C.D.3
-
61
-
-
0024421915
-
Inhibition of bacterial isoprenoid synthesis by fosmidomycin, a phosphonic acid-containing antibiotic
-
Shigi Y (1989) Inhibition of bacterial isoprenoid synthesis by fosmidomycin, a phosphonic acid-containing antibiotic. J Antimicrob Chemother 24:131-145
-
(1989)
J Antimicrob Chemother
, vol.24
, pp. 131-145
-
-
Shigi, Y.1
-
62
-
-
0037868855
-
Crystal structure of the type II isopentenyl diphosphate:Dimethylallyl diphosphate isomerase from Bacillus subtilis
-
Steinbacher S, Kaiser J, Gerhardt S, Eisenreich W, Huber R, Bacher A, Rohdich F (2003a) Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis. J Mol Biol 329:973-982
-
(2003)
J Mol Biol
, vol.329
, pp. 973-982
-
-
Steinbacher, S.1
Kaiser, J.2
Gerhardt, S.3
Eisenreich, W.4
Huber, R.5
Bacher, A.6
Rohdich, F.7
-
63
-
-
0038043258
-
Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development
-
Steinbacher S, Kaiser J, Eisenreich W, Huber R, Bacher A, Rohdich F (2003b) Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development. J Biol Chem 278:18401-18407
-
(2003)
J Biol Chem
, vol.278
, pp. 18401-18407
-
-
Steinbacher, S.1
Kaiser, J.2
Eisenreich, W.3
Huber, R.4
Bacher, A.5
Rohdich, F.6
-
64
-
-
66149104732
-
New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase
-
Unno H, Yamashita S, Ikeda Y et al (2009) New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase. J Biol Chem 284:9160-9167
-
(2009)
J Biol Chem
, vol.284
, pp. 9160-9167
-
-
Unno, H.1
Yamashita, S.2
Ikeda, Y.3
-
66
-
-
0038485617
-
Catalytic mechanism of E. Coli isopentenyl diphosphate isomerase involves Cys67, Glu116 and Tyr104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors
-
Wouters J, Oudjama Y, Barkley SJ, Tricot C, Stalon V, Droogmans L, Poulter CD (2003) Catalytic mechanism of E. coli isopentenyl diphosphate isomerase involves Cys67, Glu116 and Tyr104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors. J Biol Chem 278:11903-11908
-
(2003)
J Biol Chem
, vol.278
, pp. 11903-11908
-
-
Wouters, J.1
Oudjama, Y.2
Barkley, S.J.3
Tricot, C.4
Stalon, V.5
Droogmans, L.6
Poulter, C.D.7
-
67
-
-
0034832084
-
Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli
-
Wungsintaweekul J, Herz S, Hecht S, Eisenreich W, Feicht R, Rohdich F, Bacher A, Zenk MH (2001) Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli. Eur J Biochem 268:310-316
-
(2001)
Eur J Biochem
, vol.268
, pp. 310-316
-
-
Wungsintaweekul, J.1
Herz, S.2
Hecht, S.3
Eisenreich, W.4
Feicht, R.5
Rohdich, F.6
Bacher, A.7
Zenk, M.H.8
-
68
-
-
0032439587
-
Inhibition of the non-mevalonate 1-deoxy-D-xylulose-5-phosphate pathway of plant isoprenoid biosynthesis by fosmid-omycin
-
Zeidler J, Schwender J, Müller C et al (1998) Inhibition of the non-mevalonate 1-deoxy-D-xylulose-5-phosphate pathway of plant isoprenoid biosynthesis by fosmid-omycin. Z Naturforsch 53c:980-986
-
(1998)
Z Naturforsch
, vol.53c
, pp. 980-986
-
-
Zeidler, J.1
Schwender, J.2
Müller, C.3
-
69
-
-
0034471574
-
The non-mevalonate isoprenoid biosynthesis of plants as a test system for drugs against malaria and pathogenic bacteria
-
Zeidler J, Schwender J, Müller C, Lichtenthaler HK (2000) The non-mevalonate isoprenoid biosynthesis of plants as a test system for drugs against malaria and pathogenic bacteria. Biochem Soc Trans 28:796-798
-
(2000)
Biochem Soc Trans
, vol.28
, pp. 796-798
-
-
Zeidler, J.1
Schwender, J.2
Müller, C.3
Lichtenthaler, H.K.4
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