Risks of Death and Stroke in Patients Undergoing Hemodialysis with New-Onset Atrial Fibrillation: A Competing-Risk Analysis of a Nationwide Cohort

Circulation

Volumn 133, Issue 3, 2016, Pages 265-272

  Shih, Chia Jen ^a,b,c   Ou, Shuo Ming ^a,b   Chao, Pei Wen ^d,e   Kuo, Shu Chen ^a,b,f   Lee, Yi Jung ^a,g   Yang, Chih Yu ^a,b   Tarng, Der Cherng ^a,b   Lin, Chih Ching ^a,b   Huang, Po Hsun ^a,b   Li, Szu Yuan ^a,b   Chen, Yung Tai ^a,g  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c Deran Clinic   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^f NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^g TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

Atrial fibrillation; death; dialysis; epidemiology; risk; stroke

Indexed keywords

AGED; ATRIAL FIBRILLATION; COHORT ANALYSIS; FEMALE; FOLLOW UP; HEALTH SURVEY; HOSPITAL MORTALITY; HUMAN; MALE; MIDDLE AGED; MORTALITY; RENAL REPLACEMENT THERAPY; RETROSPECTIVE STUDY; RISK FACTOR; STATISTICS; STROKE; TAIWAN; TRENDS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ATRIAL FIBRILLATION; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; POPULATION SURVEILLANCE; RENAL DIALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; STATISTICS AS TOPIC; STROKE; TAIWAN;

EID: 84955647296     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.115.018294     Document Type: Article

References (40)

1. Winkelmayer WC, Patrick AR, Liu J, Brookhart MA, Setoguchi S, The increasing prevalence of atrial fibrillation among hemodialysis patients. J Am Soc Nephrol 2011 22 349 357. doi: 10.1681/ASN.2010050459
2. Goldstein BA, Arce CM, Hlatky MA, Turakhia M, Setoguchi S, Winkelmayer WC, Trends in the incidence of atrial fibrillation in older patients initiating dialysis in the United States. Circulation 2012 126 2293 2301. doi: 10.1161/CIRCULATIONAHA.112.099606
3. Liao JN, Chao TF, Liu CJ, Wang KL, Chen SJ, Lin YJ, Chang SL, Lo LW, Hu YF, Tuan TC, Chung FP, Chen TJ, Chen SA, Incidence and risk factors for new-onset atrial fibrillation among patients with end-stage renal disease undergoing renal replacement therapy. Kidney Int 2015 87 1209 1215. doi: 10.1038/ki.2014.393
4. Genovesi S, Vincenti A, Rossi E, Pogliani D, Acquistapace I, Stella A, Valsecchi MG, Atrial fibrillation and morbidity and mortality in a cohort of long-Term hemodialysis patients. Am J Kidney Dis 2008 51 255 262. doi: 10.1053/j.ajkd.2007.10.034
5. Vázquez E, Sánchez-Perales C, Borrego F, Garcia-Cortés MJ, Lozano C, Guzmán M, Gil JM, Borrego MJ, Pérez V, Influence of atrial fibrillation on the morbido-mortality of patients on hemodialysis. Am Heart J 2000 140 886 890
6. Zimmerman D, Sood MM, Rigatto C, Holden RM, Hiremath S, Clase CM, Systematic review and meta-Analysis of incidence, prevalence and outcomes of atrial fibrillation in patients on dialysis. Nephrol Dial Transplant 2012 27 3816 3822. doi: 10.1093/ndt/gfs416
7. Murray AM, Seliger S, Lakshminarayan K, Herzog CA, Solid CA, Incidence of stroke before and after dialysis initiation in older patients. J Am Soc Nephrol 2013 24 1166 1173. doi: 10.1681/ASN.2012080841
8. Vazquez E, Sanchez-Perales C, Garcia-Garcia F, Castellano P, Garcia-Cortes MJ, Liebana A, Lozano C, Atrial fibrillation in incident dialysis patients. Kidney Int 2009 76 324 330. doi: 10.1038/ki.2009.185
9. Chou CY, Kuo HL, Wang SM, Liu JH, Lin HH, Liu YL, Huang CC, Outcome of atrial fibrillation among patients with end-stage renal disease. Nephrol Dial Transplant 2010 25 1225 1230. doi: 10.1093/ndt/gfp589
10. January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW, ACC/AHA Task Force Members 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society. Circulation 2014 130 2071 2104. doi: 10.1161/CIR.0000000000000040
11. Winkelmayer WC, Liu J, Setoguchi S, Choudhry NK, Effectiveness and safety of warfarin initiation in older hemodialysis patients with incident atrial fibrillation. Clin J Am Soc Nephrol 2011 6 2662 2668. doi: 10.2215/CJN.04550511
12. Shah M, Avgil Tsadok M, Jackevicius CA, Essebag V, Eisenberg MJ, Rahme E, Humphries KH, Tu JV, Behlouli H, Guo H, Pilote L, Warfarin use and the risk for stroke and bleeding in patients with atrial fibrillation undergoing dialysis. Circulation 2014 129 1196 1203. doi: 10.1161/CIRCULATIONAHA.113.004777
13. Chen JJ, Lin LY, Yang YH, Hwang JJ, Chen PC, Lin JL, Anti-platelet or anti-coagulant agent for the prevention of ischemic stroke in patients with end-stage renal disease and atrial fibrillation-A nation-wide database analyses. Int J Cardiol 2014 177 1008 1011. doi: 10.1016/j.ijcard.2014.09.140
14. Sood MM, Larkina M, Thumma JR, Tentori F, Gillespie BW, Fukuhara S, Mendelssohn DC, Chan K, de Sequera P, Komenda P, Rigatto C, Robinson BM, Major bleeding events and risk stratification of antithrombotic agents in hemodialysis: results from the DOPPS. Kidney Int 2013 84 600 608. doi: 10.1038/ki.2013.170
15. Wizemann V, Tong L, Satayathum S, Disney A, Akiba T, Fissell RB, Kerr PG, Young EW, Robinson BM, Atrial fibrillation in hemodialysis patients: clinical features and associations with anticoagulant therapy. Kidney Int 2010 77 1098 1106. doi: 10.1038/ki.2009.477
16. Chan KE, Lazarus JM, Thadhani R, Hakim RM, Warfarin use associates with increased risk for stroke in hemodialysis patients with atrial fibrillation. J Am Soc Nephrol 2009 20 2223 2233. doi: 10.1681/ASN.2009030319
17. Olesen JB, Lip GY, Kamper AL, Hommel K, Køber L, Lane DA, Lindhardsen J, Gislason GH, Torp-Pedersen C, Stroke and bleeding in atrial fibrillation with chronic kidney disease. N Engl J Med 2012 367 625 635. doi: 10.1056/NEJMoa1105594
18. Reinecke H, Brand E, Mesters R, Schäbitz WR, Fisher M, Pavenstädt H, Breithardt G, Dilemmas in the management of atrial fibrillation in chronic kidney disease. J Am Soc Nephrol 2009 20 705 711. doi: 10.1681/ASN.2007111207
19. Shih CJ, Chu H, Chao PW, Lee YJ, Kuo SC, Li SY, Tarng DC, Yang CY, Yang WC, Ou SM, Chen YT, Long-Term clinical outcome of major adverse cardiac events in survivors of infective endocarditis: a nationwide population-based study. Circulation 2014 130 1684 1691. doi: 10.1161/CIRCULATIONAHA.114.012717
20. Chao PW, Shih CJ, Lee YJ, Tseng CM, Kuo SC, Shih YN, Chou KT, Tarng DC, Li SY, Ou SM, Chen YT, Association of postdischarge rehabilitation with mortality in intensive care unit survivors of sepsis. Am J Respir Crit Care Med 2014 190 1003 1011. doi: 10.1164/rccm.201406-1170OC
21. Fischer KG, Essentials of anticoagulation in hemodialysis. Hemodial Int 2007 11 178 189. doi: 10.1111/j.1542-4758.2007.00166.x
22. Davenport A, What are the anticoagulation options for intermittent hemodialysis? Nat Rev Nephrol 2011 7 499 508. doi: 10.1038/nrneph.2011.88
23. Chang CH, Lee YC, Tsai CT, Chang SN, Chung YH, Lin MS, Lin JW, Lai MS, Continuation of statin therapy and a decreased risk of atrial fibrillation/flutter in patients with and without chronic kidney disease. Atherosclerosis 2014 232 224 230. doi: 10.1016/j.atherosclerosis.2013.11.036
24. Lin LJ, Cheng MH, Lee CH, Wung DC, Cheng CL, Kao Yang YH, Compliance with antithrombotic prescribing guidelines for patients with atrial fibrillation-A nationwide descriptive study in Taiwan. Clin Ther 2008 30 1726 1736. doi: 10.1016/j.clinthera.2008.09.010
25. Tsai WC, Chen CY, Kuo HF, Wu MT, Tang WH, Chu CS, Lin TH, Su HM, Hsu PC, Jhuo SJ, Lin MY, Lee KT, Sheu SH, Lai WT, Areca nut chewing and risk of atrial fibrillation in Taiwanese men: a nationwide ecological study. Int J Med Sci 2013 10 804 811. doi: 10.7150/ijms.5998
26. Charlson ME, Pompei P, Ales KL, MacKenzie CR, A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987 40 373 383
27. Cheng CL, Kao YH, Lin SJ, Lee CH, Lai ML, Validation of the National Health Insurance Research Database with ischemic stroke cases in Taiwan. Pharmacoepidemiol Drug Saf 2011 20 236 242. doi: 10.1002/pds.2087
28. Hsieh CY, Chen CH, Li CY, Lai ML, Validating the diagnosis of acute ischemic stroke in a National Health Insurance claims database. J Formos Med Assoc 2015 114 254 259. doi: 10.1016/j.jfma.2013.09.009
29. Cheng CL, Lee CH, Chen PS, Li YH, Lin SJ, Yang YH, Validation of acute myocardial infarction cases in the national health insurance research database in taiwan. J Epidemiol 2014 24 500 507
30. Fine JP, Gray RJ, A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 1999 94 496 509
31. Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ, Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA 2001 285 2864 2870
32. Lip GY, Nieuwlaat R, Pisters R, Lane DA, Crijns HJ, Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest 2010 137 263 272. doi: 10.1378/chest.09-1584
33. Quinn RR, Naimark DM, Oliver MJ, Bayoumi AM, Should hemodialysis patients with atrial fibrillation undergo systemic anticoagulation? A cost-utility analysis. Am J Kidney Dis 2007 50 421 432. doi: 10.1053/j.ajkd.2007.05.019
34. Chao TF, Liu CJ, Wang KL, Lin YJ, Chang SL, Lo LW, Hu YF, Tuan TC, Chung FP, Liao JN, Chen TJ, Lip GY, Chen SA, Incidence and prediction of ischemic stroke among atrial fibrillation patients with end-stage renal disease requiring dialysis. Heart Rhythm 2014 11 1752 1759. doi: 10.1016/j.hrthm.2014.06.021
35. Lin CC, Lai MS, Syu CY, Chang SC, Tseng FY, Accuracy of diabetes diagnosis in health insurance claims data in Taiwan. J Formos Med Assoc 2005 104 157 163
36. Takeda K, Harada A, Okuda S, Fujimi S, Oh Y, Hattori F, Motomura K, Hirakata H, Fujishima M, Sudden death in chronic dialysis patients. Nephrol Dial Transplant 1997 12 952 955
37. Hart RG, Pearce LA, Rothbart RM, McAnulty JH, Asinger RW, Halperin JL, Stroke with intermittent atrial fibrillation: incidence and predictors during aspirin therapy. Stroke Prevention in Atrial Fibrillation Investigators. J Am Coll Cardiol 2000 35 183 187
38. Hohnloser SH, Pajitnev D, Pogue J, Healey JS, Pfeffer MA, Yusuf S, Connolly SJ, ACTIVE W Investigators Incidence of stroke in paroxysmal versus sustained atrial fibrillation in patients taking oral anticoagulation or combined antiplatelet therapy: an ACTIVE W Substudy. J Am Coll Cardiol 2007 50 2156 2161. doi: 10.1016/j.jacc.2007.07.076
39. Patel MR, Mahaffey KW, Garg J, Pan G, Singer DE, Hacke W, Breithardt G, Halperin JL, Hankey GJ, Piccini JP, Becker RC, Nessel CC, Paolini JF, Berkowitz SD, Fox KA, Califf RM, ROCKET AF Investigators Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 2011 365 883 891. doi: 10.1056/NEJMoa1009638
40. Giugliano RP, Ruff CT, Braunwald E, Murphy SA, Wiviott SD, Halperin JL, Waldo AL, Ezekowitz MD, Weitz JI, Špinar J, Ruzyllo W, Ruda M, Koretsune Y, Betcher J, Shi M, Grip LT, Patel SP, Patel I, Hanyok JJ, Mercuri M, Antman EM, ENGAGE AF-TIMI 48 Investigators Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2013 369 2093 2104. doi: 10.1056/NEJMoa1310907