The impact of maternal hypothyroidism during pregnancy on neonatal outcomes: A systematic review and meta-analysis

Gynecological Endocrinology

Volumn 32, Issue 1, 2016, Pages 9-13

  Hou, Jiatong ^a   Yu, Ping ^a   Zhu, Huijuan ^a   Pan, Hui ^a   Li, Naishi ^a   Yang, Hongbo ^a   Jiang, Yu ^b   Wang, Linjie ^a   Wang, Bo ^b   Wang, Yanhong ^b   You, Lili ^b   Chen, Shi ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Birth weight; hypothyroidism; neonatal outcomes; pregnancy

Indexed keywords

THYROXINE;

BIRTH WEIGHT; FEMALE; FETAL MACROSOMIA; HORMONE SUBSTITUTION; HUMAN; HYPOTHYROIDISM; LOW BIRTH WEIGHT; META ANALYSIS; NEWBORN; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY OUTCOME; PREMATURE BIRTH;

BIRTH WEIGHT; FEMALE; FETAL MACROSOMIA; HORMONE REPLACEMENT THERAPY; HUMANS; HYPOTHYROIDISM; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY OUTCOME; PREMATURE BIRTH; THYROXINE;

EID: 84955641446     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513590.2015.1104296     Document Type: Article

References (27)

1. Morreale de Escobar G, Obregon MJ, Escobar del Rey F. Role of thyroid hormone during early brain development. Eur J Endocrinol 2004; 151: U25-37
2. Poppe K, Velkeniers B, Glinoer D. The role of thyroid autoimmunity in fertility and pregnancy. Nat Clin Pract Endoc 2008; 4: 394-405
3. Blazer S, Moreh-Waterman Y, Miller-Lotan R, et al. Maternal hypothyroidism may affect fetal growth and neonatal thyroid function. Obstet Gynecol 2003; 102: 232-41
4. McIntire DD, Bloom SL, Casey BM, Leveno KJ. Birth weight in relation to morbidity and mortality among newborn infants. New Engl J Med 1999; 340: 1234-8
5. Krassas GE, Poppe K, Glinoer D. Thyroid function and human reproductive health. Endocr Rev 2010; 31: 702-55
6. Schneuer FJ, Nassar N, Tasevski V, et al. Association and predictive accuracy of high TSH serum levels in first trimester and adverse pregnancy outcomes. J Clin Endocr Metab 2012; 97: 3115-22
7. Karakosta P, Alegakis D, Georgiou V, et al. Hypothyroidism and autoantibodies in early pregnancy are associated with increased risk of gestational diabetes and adverse birth outcomes. J Clin Endocr Metab 2012; 97: 4464-72
8. Allan WC, Haddow JE, Palomaki GE, et al. Maternal thyroid deficiency and pregnancy complications: implications for population screening. J Med Screen 2000; 7: 127-30
9. Casey BM, Dashe JS, Wells CE, et al. Subclinical hypothyroidism and pregnancy outcomes. Obstet Gynecol 2005; 105: 239-45
10. Leung AS, Millar LK, Koonings PP, et al. Perinatal outcome in hypothyroid pregnancies. Obstet Gynecol 1993; 81: 349-53
11. Cleary-Goldman J, Malone FD, Lambert-Messerlian G, et al. Maternal thyroid hypofunction and pregnancy outcome. Obstet Gynecol 2008; 112: 85-92
12. Mannisto T, Vaarasmaki M, Pouta A, et al. Perinatal outcome of children born to mothers with hypothyroidism or antibodies: a prospective population-based cohort study. J Clin Endocr Metab 2009; 94: 772-9
13. Stagnaro-Green A. Thyroid antibodies and miscarriage: where are we at a generation later? J Thyroid Res 2011; 2011: 841949
14. Challis JR, Lockwood CJ, Myatt L, et al. Inflammation and pregnancy. Reprod Sci 2009; 16: 206-15
15. Stagnaro-Green A. Maternal thyroid disease and preterm delivery. J Clin Endocr Metab 2009; 94: 21-5
16. Condon JC, Jeyasuria P, Faust JM, Mendelson CR. Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition. Proc Natl Acad Sci USA 2004; 101: 4978-83
17. Salminen A, Vuolteenaho R, Paananen R, et al. Surfactant protein A modulates the lipopolysaccharide-induced inflammatory response related to preterm birth. Cytokine 2011; 56: 442-9
18. van Tuyl M, Blommaart PE, de Boer PA, et al. Prenatal exposure to thyroid hormone is necessary for normal postnatal development of murine heart and lungs. Dev Biol 2004; 272: 104-17
19. Ramadurai SM, Nielsen HC, Chen Y, et al. Differential effects in vivo of thyroid hormone on the expression of surfactant phospholipid, surfactant protein mRNA and antioxidant enzyme mRNA in fetal rat lung. Exp Lung Res 1988; 24: 641-57
20. Ciosek J, Drobnik J. Vasopressin and oxytocin release and the thyroid function. J Physiol Pharmacol 2004; 55: 423-41
21. Andersen SL, Olsen J, Wu CS, Laurberg P. Low birth weight in children born to mothers with hyperthyroidism and high birth weight in hypothyroidism, whereas preterm birth is common in both conditions: a Danish National Hospital Register Study. Eur Thyroid J 2013; 2: 135-44
22. Simas TA, Waring ME, Liao X, et al. Prepregnancy weight, gestational weight gain, and risk of growth affected neonates. J Womens Health 2012; 21: 410-17
23. Laurberg P, Knudsen N, Andersen S, et al. Thyroid function and obesity. Eur Thyroid J 2012; 1: 159-67
24. Wang S, Teng WP, Li JX, et al. Effects of maternal subclinical hypothyroidism on obstetrical outcomes during early pregnancy. J Endocrinol Invest 2012;35:322-5
25. Su PY, Huang K, Hao JH, et al. Maternal thyroid function in the first twenty weeks of pregnancy and subsequent fetal and infant development: a prospective population-based cohort study in China. J Clin Endocrinol Metab 2011;96:3234-41
26. Finken MJ, van Eijsden M, Loomans EM, et al. Maternal hypothyroxinemia in early pregnancy predicts reduced performance in reaction time tests in 5-To 6-year-old offspring. J Clin Endocrinol Metab 2013;98:1417-26
27. Matalon S, Sheiner E, Levy A, et al. Relationship of treated maternal hypothyroidism and perinatal outcome. J Reprod Med 2006;51:59-63