Potentially inappropriate prescribing in two populations with differing socio-economic profiles: A cross-sectional database study using the PROMPT criteria

European Journal of Clinical Pharmacology

Volumn 72, Issue 5, 2016, Pages 583-591

  Cooper, Janine A ^a,b   Moriarty, Frank ^b   Ryan, Cristín ^b   Smith, Susan M ^b   Bennett, Kathleen ^c   Fahey, Tom ^b   Wallace, Emma ^b   Cahir, Caitriona ^c,d   Williams, David ^b   Teeling, Mary ^c   Hughes, Carmel M ^a,b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^c ST JAMES S HOSPITAL   (Ireland)

^d ECONOMIC AND SOCIAL RESEARCH INSTITUTE   (Ireland)

Author keywords

Explicit criteria; Middle age; Polypharmacy; Potentially inappropriate prescribing; PROMPT

Indexed keywords

ANTIHISTAMINIC AGENT; BENZODIAZEPINE DERIVATIVE; HYPNOTIC AGENT; LAXATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PROTON PUMP INHIBITOR;

ADULT; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DATA BASE; FEMALE; GROUPS BY AGE; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; POLYPHARMACY; POPULATION; POTENTIALLY INAPPROPRIATE MEDICATION; PREVALENCE; PRIORITY JOURNAL; REIMBURSEMENT; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEX DIFFERENCE; SOCIOECONOMICS; UNITED KINGDOM; FACTUAL DATABASE; INAPPROPRIATE PRESCRIBING; IRELAND; NORTHERN IRELAND; STATISTICS AND NUMERICAL DATA;

CROSS-SECTIONAL STUDIES; DATABASES, FACTUAL; FEMALE; HUMANS; INAPPROPRIATE PRESCRIBING; IRELAND; MALE; MIDDLE AGED; NORTHERN IRELAND; POLYPHARMACY; PREVALENCE; RETROSPECTIVE STUDIES; SOCIOECONOMIC FACTORS;

EID: 84955600179     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-015-2003-z     Document Type: Article

References (31)

1. Guthrie B, Payne K, Alderson P, et al. (2012) Adapting clinical guidelines to take account of multimorbidity. BMJ 345:e6341. doi: 10.1136/bmj.e6341
2. Barnett K, Mercer SW, Norbury M, et al. (2012) Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet 380:37-43. doi: 10.1016/S0140-6736(12)60240-2
3. Mangoni AA, Jackson SHD (2003) Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol 57:6-14. doi: 10.1046/j.1365-2125.2003.02007.x
4. Marengoni A, Angleman S, Melis R, et al. (2011) Aging with multimorbidity: a systematic review of the literature. Ageing Res Rev 10:430-439. doi: 10.1016/j.arr.2011.03.003
5. Fried TR, O'Leary J, Towle V, et al. (2014) Health outcomes associated with polypharmacy in community-dwelling older adults: a systematic review. J Am Geriatr Soc 62:2261-2272. doi: 10.1111/jgs.13153
6. Hughes C, Cooper J, Ryan C (2014) Going beyond the numbers - a call to redefine polypharmacy. Br J Clin Pharmacol 77:915-916. doi: 10.1002/14651858
7. O'Connor MN, Gallagher P, O'Mahony D (2012) Inappropriate prescribing. Criteria, detection and prevention. Drugs Aging 29:437-452
8. Cooper JA, Ryan C, Smith SM, et al. (2014) The development of the PROMPT (PRescribing optimally in middle-aged people's treatments) criteria. BMC Health Serv Res 14:484. doi: 10.1186/s12913-014-0484-6
9. American Geriatrics Society (2015) Beers criteria update expert panel (2015) American geriatrics society 2015 updated beers criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. doi: 10.1111/jgs.13702
10. O'Mahony D, O'Sullivan D, Byrne S, et al. (2015) STOPP/START criteria for potentially inappropriate prescribing in older people: version 2. Age Ageing 44:213-218. doi: 10.1093/ageing/afu145
11. Laroche M-L, Charmes J-P, Merle L (2007) Potentially inappropriate medications in the elderly: a French consensus panel list. Eur J Clin Pharmacol 63:725-731. doi: 10.1007/s00228-007-0324-2
12. McLeod PJ, Huang AR, Tamblyn RM, Gayton DC (1997) Defining inappropriate practices in prescribing for elderly people: a national consensus panel. Can Med Assoc J 156:385-391
13. Hanlon JT, Schmader KE, Samsa GP, et al. (1992) A method for assessing drug therapy appropriateness. J Clin Epidemiol 45:1045-1051. doi: 10.1016/0895-4356(92)90144-C
14. Bradley MC, Fahey T, Cahir C, et al. (2012) Potentially inappropriate prescribing and cost outcomes for older people: a cross-sectional study using the Northern Ireland enhanced prescribing database. Eur J Clin Pharmacol 68:1425-1433. doi: 10.1007/s00228-012-1249-y
15. Northern Ireland Statistics and Research Agency (2012) Census 2011. Population and household estimates by local government district for Northern Ireland. Belfast
16. Health Service Executive (2012) Primary care reimbursement service annual report. Dublin
17. Central Statistics Office Population estimates. http://www.cso.ie/px/pxeirestat/Statire/SelectVarVal/Define.asp?maintable=PEA01&PLanguage=0. Accessed 10 Mar 2015
18. Bradley MC, Motterlini N, Padmanabhan S, et al. (2014) Potentially inappropriate prescribing among older people in the United Kingdom. BMC Geriatr 14:72. doi: 10.1186/1471-2318-14-72
19. Patterson S, Cadogan C, Kerse N, et al. (2014) Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev CD008165. doi: 10.1002/14651858.CD008165.pub3
20. Smith SK, Dixon A, Trevena L, et al. (2009) Exploring patient involvement in healthcare decision making across different education and functional health literacy groups. Soc Sci Med 69:1805-1812. doi: 10.1016/j.socscimed.2009.09.056
21. Willems S, De Maesschalck S, Deveugele M, et al. (2005) Socio-economic status of the patient and doctor-patient communication: does it make a difference? Patient Educ Couns 56:139-146. doi: 10.1016/j.pec.2004.02.011
22. Mercer SW, Watt GC (2007) The inverse care law: clinical primary care encounters in deprived and affluent areas of Scotland. Ann Fam Med 5:503-510. doi: 10.1370/afm.778
23. McLean G, Gunn J, Wyke S, et al. (2014) The influence of socioeconomic deprivation on multimorbidity at different ages: a cross-sectional study. Br J Gen Pract 64:e440-e447. doi: 10.3399/bjgp14X680545
24. Charlton J, Rudisill C, Bhattarai N, Gulliford M (2013) Impact of deprivation on occurrence, outcomes and health care costs of people with multiple morbidity. J Health Serv Res Policy 18:215-223. doi: 10.1177/1355819613493772
25. Payne R, Avery A, Duerden M, et al. (2014) Prevalence of polypharmacy in a Scottish primary care population. Eur J Clin Pharmacol 70:575-581. doi: 10.1007/s00228-013-1639-9
26. Richardson K, Moore P, Peklar J, et al. (2012) TILDA: polypharmacy in adults over 50 in Ireland: opportunities for cost saving and improved healthcare. Dublin
27. Odubanjo E, Bennett K, Feely J (2004) Influence of socioeconomic status on the quality of prescribing in the elderly - a population based study. Br J Clin Pharmacol 58:496-502. doi: 10.1111/j.1365-2125.2004.02179.x
28. Guthrie B, McCowan C, Davey P, et al. (2011) High risk prescribing in primary care patients particularly vulnerable to adverse drug events: cross sectional population database analysis in Scottish general practice. BMJ 342:d3514. doi: 10.1136/bmj.d3514
29. Busfield J (2010) "A pill for every ill": explaining the expansion in medicine use. Soc Sci Med 70:934-941. doi: 10.1016/j.socscimed.2009.10.068
30. Gallagher P, Ryan C, Byrne S, et al. (2008) STOPP (screening tool of older person's prescriptions) and START (screening tool to alert doctors to right treatment). consensus validation. Int J Clin Pharmacol Ther 46:72-83
31. Cahir C, Fahey T, Teeling M, et al. (2010) Potentially inappropriate prescribing and cost outcomes for older people: a national population study. Br J Clin Pharmacol 69:543-552. doi: 10.1111/j.1365-2125.2010.03628.x