Biomechanical properties and microstructural analysis of the human nonaneurysmal aorta as a function of age, gender and location: An autopsy study

Journal of Vascular Research

Volumn 52, Issue 4, 2016, Pages 257-264

  Ninomiya, Otavio Henrique ^a   Tavares Monteiro, José Augusto ^a   Higuchi, Maria De Lourdes ^a   Puech Leão, Pedro ^a   De Luccia, Nelson ^a   Raghavan, Madhavan Lakshmi ^b   Da Silva, Erasmo Simão ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b IA United States   (United States)

Author keywords

Biomechanics; Elasticity; Histology; Human aorta; Mechanical stress

Indexed keywords

COLLAGEN; ELASTIN;

ABDOMINAL AORTA; ADULT; AGE; AGED; AORTA; ARTICLE; AUTOPSY; BIOMECHANICS; BLOOD VESSEL TONE; BLOOD VESSEL WALL; CADAVER; CONTROLLED STUDY; CORRELATIONAL STUDY; ELASTIC FIBER; EXPERIMENTAL STUDY; FEMALE; GENDER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; MIDDLE AGED; PRIORITY JOURNAL; SEX DIFFERENCE; STRUCTURE ANALYSIS; THORACIC AORTA; TUNICA MEDIA; VERY ELDERLY; AGING; ARTERIAL STIFFNESS; COMPARATIVE STUDY; ELASTIC TISSUE; ELASTICITY; MECHANICAL STRESS; PATHOLOGY; PATHOPHYSIOLOGY;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; AORTA, ABDOMINAL; AORTA, THORACIC; AUTOPSY; BIOMECHANICAL PHENOMENA; ELASTIC TISSUE; ELASTICITY; FEMALE; HUMANS; MALE; MIDDLE AGED; SEX FACTORS; STRESS, MECHANICAL; VASCULAR STIFFNESS;

EID: 84955586147     PISSN: 10181172     EISSN: 14230135     Source Type: Journal    
DOI: 10.1159/000442979     Document Type: Article

References (27)

1. Hallock P, Benson IC. Studies on the elastic properties of human isolated aorta. J Clin Invest 1937; 16: 595-602
2. Sonesson B, Lanne T, Vernersson E, Hansen F: Sex difference in the mechanical properties of the abdominal aorta in human beings. J Vasc Surg 1994; 20: 959-969
3. Haskett D, Johnson G, Zhou A, Ultzinger U, Vande Geest J: Microstructural and biomechanical alterations of the human aorta as a function of age and location. Biomech Model Mechanobiol 2010; 9: 725-736
4. Lanne T, Sonesson B, Bergqvist D, Bengtsson H, Gustafsson D: Diameter and compliance in the male human abdominal aorta: influence of age and aortic diameter. Eur J Vasc Surg 1992; 6: 178-184
5. Astrand H, Ryden-Ahlgren A, Sandgren T, Lanne T: Age-related increase in wall stress of the human abdominal aorta: An in vivo study. J Vasc Surg 2005; 42: 926-931
6. Benvenuti LA, Onishi RY, Gutierrez PS, Higuchi ML. Different patterns of atherosclerotic remodeling in the thoracic and abdominal aorta. Clinics 2005; 60: 355-360
7. Schlatmann TJ, Becker AE. Histologic changes in the normal aging aorta: implications for dissecting aortic aneurysm. Am J Cardiol 1977; 39: 13-20
8. Dingemans KP, Jansen N, Becker AE. Ultrastructure of the normal human aortic media. Virchows Arch A Pathol Anat Histol 1981; 392: 199-216
9. Halloran BG, Davis VA, McManus BM, Lynch TG, Baxter BT. Localization of aortic disease is associated with intrinsic differences in aortic structure. J Surg Res 1995; 59: 17-22
10. Tsamis A, Krawiec JT, Vorp DA. Elastin and collagen fibre microstructure of the human aorta in ageing and disease: A review. J R Soc Interface 2013; 10: 1-22
11. Wolinsky H, Glagov S: Structural basis for the static mechanical properties of the aortic media. Circ Res 1964; 14: 400-413
12. Sherebrin MH, Hegney JE, Roach MR. Effects of age on the anisotropy of the descending human thoracic aorta determined by uniaxial tensile testing and digestion by NaOH under load. Can J Physiol Pharmacol 1989; 67: 871-878
13. Baxter BT, McGee GS, Shively VP, Drummond IA, Dixit SN, Yamauchi M., et al. Elastin content, cross-links, and mRNA in normal and aneurysmal human aorta. J Vasc Surg 1992; 16: 192-200
14. He CM, Roach MR. The composition and mechanical properties of abdominal aortic aneurysms. J Vasc Surg 1994; 20: 6-13
15. Mohan D, Melvin JW. Failure properties of passive human aortic tissue. I. Uniaxial tension tests. J Biomech 1982; 15: 887-902
16. Raghavan ML, Webster MW, Vorp DA. Ex vivo biomechanical behavior of abdominal aortic aneurysm: Assessment using a new mathematical model. Ann Biomed Eng 1996; 24: 573-582
17. Vorp DA, Raghavan ML, Muluk SC, Makaroun MS, Steed DL, Shapiro R., et al. Wall strength and stiffness of aneurysmal and nonaneurysmal abdominal aorta. Ann NY Acad Sci 1996; 800: 274-276
18. Xiong J, Wang SM, Zhou W, Wu JG. Measurement and analysis of ultimate mechanical properties, stress-strain curve fit, and elastic modulus formula of human abdominal aortic aneurysm and nonaneurysmal abdominal aorta. J Vasc Surg 2008; 48: 189-195
19. Sincos IR, Da Silva ES, Belczak SQ, Baptista Sincos AP, Higuchi ML, Gornati V., et al. Histologic analysis of stent graft oversizing in the thoracic aorta. J Vasc Surg 2013; 58: 1644-1651
20. Raghavan ML, Hanaoka MM, Kratzberg JA, Higuchi ML, Da Silva ES. Biomechanical failure properties and microstructural content of ruptured and unruptured abdominal aortic aneurysms. J Biomech 2011; 44: 2501-2507
21. Assoul N, Flaud P, Chaouat M, Letourneur D, Bataille I: Mechanical properties of rat thoracic and abdominal aortas. J Biomech 2008; 41: 2227-2236
22. Di Martino ES, Bohra A, Vande Geest JP, Gupta N, Makaroun MS, Vorp DA. Biomechanical properties of ruptured versus electively repaired abdominal aortic aneurysm wall tissue. J Vasc Surg 2006; 43: 570-576
23. Thubrikar MJ, Labrosse M, Robicsek F, Al- Soudi J, Fowler B: Mechanical properties of abdominal aortic aneurysm wall. J Med Eng Technol 2001; 25: 133-142
24. Raghavan ML, Kratzberg J, Castro de Tolosa EM, Hanaoka MM, Walker P, Da Silva ES. Regional distribution of wall thickness and failure properties of human abdominal aortic aneurysm. J Biomech 2006; 39: 3010-3016
25. Vande Geest JP, Dillavou ED, Di Martino ES, Oberdier M, Bohra A, Makaroun MS., et al. Gender-related differences in the tensile strength of abdominal aortic aneurysm. Ann NY Acad Sci 2006; 1085: 400-402
26. Tavares Monteiro JA, Da Silva ES, Raghavan ML, Puech-Leao P, Higuchi ML, Otoch JP. Histologic, histochemical and biomechanical properties of fragments isolated from the anterior wall of abdominal aortic aneurysms. J Vasc Surg 2014; 59: 1393-1401
27. Norman PE, Powell JT. Abdominal aortic aneurysm: the prognosis in women is worse than in men. Circulation 2007; 115: 2865-2869