The Effect of Deworming on Growth in One-Year-Old Children Living in a Soil-Transmitted Helminth-Endemic Area of Peru: A Randomized Controlled Trial

PLoS Neglected Tropical Diseases

Volumn 9, Issue 10, 2015, Pages

  Joseph, Serene A ^a,b   Casapía, Martín ^c   Montresor, Antonio ^d   Rahme, Elham ^a,b   Ward, Brian J ^b,e   Marquis, Grace S ^f   Pezo, Lidsky ^c   Blouin, Brittany ^a,b   Maheu Giroux, Mathieu ^g   Gyorkos, Theresa W ^a,b,e  

^a MCGILL UNIVERSITY   (Canada)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c ASOCIACIÓN CIVIL SELVA AMAZÓNICA   (Peru)

^d WORLD HEALTH ORGANIZATION   (Switzerland)

^e MCGILL UNIVERSITY   (Canada)

^f MCGILL UNIVERSITY   (Canada)

^g ST MARY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MEBENDAZOLE; PLACEBO; SOIL;

ANTHROPOMETRIC PARAMETERS; ARTICLE; ASCARIS LUMBRICOIDES; CHILD; CHILD GROWTH; DOUBLE BLIND PROCEDURE; FECES ANALYSIS; FEMALE; FOLLOW UP; HELMINTHIASIS; HOOKWORM; HUMAN; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OUTCOME ASSESSMENT; PARALLEL DESIGN; PATIENT COMPLIANCE; PERU; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TREATMENT OUTCOME; TRICHURIS TRICHIURA; WEIGHT GAIN; BODY HEIGHT; BODY WEIGHT; CONTROLLED STUDY; ENDEMIC DISEASE; FECES; INFANT; PARASITOLOGY; PATHOPHYSIOLOGY; SOIL; TIME FACTOR;

BODY HEIGHT; BODY WEIGHT; DOUBLE-BLIND METHOD; ENDEMIC DISEASES; FECES; FEMALE; HELMINTHIASIS; HUMANS; INFANT; MALE; PATIENT COMPLIANCE; SOIL; TIME FACTORS;

EID: 84955579234     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0004020     Document Type: Article

References (38)

1. Pullan RL, Smith JL, Jasrasaria R, Brooker SJ, (2014) Global numbers of infection and disease burden of soil transmitted helminth infections in 2010. Parasit Vectors7: 37. doi: 10.1186/1756-3305-7-3724447578
2. Stephenson LS, (1987) The impact of helminth infections on human nutrition: Schistosomes and soil-transmitted helminths. London: Taylor & Francis Ltd.
3. Crompton DW, (2000) The public health importance of hookworm diseases. Parasitology121: 39–50.
4. WHO (2005) Deworming for health and development. Geneva, Switzerland: World Health Organization. WHO/CDS/CPE/PVC/2005.14.
5. WHO (2006) Preventive chemotherapy in human helminthiasis—Coordinated use of anthelminthic drugs in control interventions: a manual for health professionals and programme managers. Geneva, Switzerland: World Health Organization. 62 p.
6. Hall A, Hewitt G, Tuffrey V, de Silva N, (2008) A review and meta-analysis of the impact of intestinal worms on child growth and nutrition. Matern Child Nutr4: 118–236. doi: 10.1111/j.1740-8709.2007.00127.x18289159
7. WHO (2014) Soil-transmitted helminthiases: number of children treated in 2012. Wkly Epidemiol Rec89: 133–140. 24707519
8. WHO (2011) Soil-transmitted helminthiases: estimates of the number of children needing preventive chemotherapy and number treated, 2009. Wkly Epidemiol Rec86: 257–268. 21706909
9. WHO (2002) Report of the WHO informal consultation on the use of Praziquantel during pregnancy/lactation and Albendazole/Mebendazole in children under 24 months. Geneva, Switzerland: WHO/CDS/CPE/PVC. 49 p.
10. Allen HE, Crompton DW, de Silva N, LoVerde PT, Olds GR, (2002) New policies for using anthelmintics in high risk groups. Trends Parasitol18: 381–382. 12377247
11. Montresor A, Awasthi S, Crompton DWT, (2003) Use of benzimidazoles in children younger than 24 months for the treatment of soil-transmitted helminthiasis. Acta Trop86: 223–232. 12745139
12. Stoltzfus RJ, Chway HM, Montresor A, Tielsch JM, Jape JK, et al. (2004) Low dose daily iron supplementation improves iron status and appetite but not anemia, whereas quarterly anthelminthic treatment improves growth, appetite and anemia in Zanzibari preschool children. J Nutr134: 348–356. 14747671
13. Gyorkos TW, Maheu-Giroux M, Casapía M, Joseph SA, Creed-Kanashiro H, (2011) Stunting and helminth infection in early preschool-age children in a resource-poor community in the Amazon lowlands of Peru. Trans R Soc Trop Med Hyg105: 204–208. doi: 10.1016/j.trstmh.2010.12.00321349565
14. Joseph SA, Casapia M, Blouin B, Maheu-Giroux M, Rahme E, et al. (2014) Risk factors associated with malnutrition in one-year-old children living in the Peruvian Amazon. PLoS Negl Trop Dis8: e3369. doi: 10.1371/journal.pntd.000336925503381
15. Menzies SK, Rodriguez A, Chico M, Sandoval C, Broncano N, et al. (2014) Risk factors for soil-transmitted helminth infections during the first 3 years of life in the tropics; findings from a birth cohort. PLoS Negl Trop Dis8: e2718. doi: 10.1371/journal.pntd.000271824587469
16. Victora CG, de Onis M, Hallal PC, Blössner M, Shrimpton R, (2010) Worldwide timing of growth faltering: revisiting implications for interventions. Pediatrics125: 473–480.
17. Bryce J, Coitinho D, Darnton-Hill I, Pelletier D, Pinstrup-Andersen P, et al. (2008) Maternal and child undernutrition: effective action at national level. Lancet371: 510–526. doi: 10.1016/S0140-6736(07)61694-818206224
18. Taylor-Robinson DC, Jones AP, Garner P, (2007) Deworming drugs for treating soil-transmitted intestinal worms in children: effects on growth and school performance. Cochrane Database Syst Rev7: CD000371.
19. Taylor-Robinson DC, Maayan N, Soares-Weiser K, Donegan S, Garner P, (2012) Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin and school performance. Cochrane Database Syst Rev11: CD000371. doi: 10.1002/14651858.CD000371.pub523152203
20. Awasthi S, Peto R, Pande VK, Fletcher RH, Read S, et al. (2008) Effects of deworming on malnourished preschool children in India: an open-labelled, cluster-randomized trial. PLoS Negl Trop Dis2: e223. doi: 10.1371/journal.pntd.000022318414647
21. Awasthi S, Peto R, Read S, Richards SM, Pande V, et al. (2013) Population deworming every 6 months with albendazole in 1 million pre-school children in North India: DEVTA, a cluster-randomised trial. Lancet381: 1478–1486. doi: 10.1016/S0140-6736(12)62126-623498850
22. Ndibazza J, Mpairwe H, Webb EL, Mawa PA, Nampijja M, et al. (2012) Impact of anthelminthic treatment in pregnancy and childhood on immunisations, infections and eczema in childhood: a randomised controlled trial. PLoS One7: e50325. doi: 10.1371/journal.pone.005032523236367
23. Albonico M, Allen H, Chitsulo L, Engels D, Gabrielli A-F, et al. (2008) Controlling soil-transmitted helminthiasis in pre-school-age children through preventive chemotherapy. PLoS Negl Trop Dis2: e126. doi: 10.1371/journal.pntd.000012618365031
24. MINSA (2011) Norma técnica de salud para el control del crecimiento y desarrollo de la niña y el niño menor de cinco años.: Lima, Peru. Ministerio de Salud. Dirección General de Salud de las Personas. 150 p.
25. Larocque R, Casapia M, Gotuzzo E, MacLean JD, Soto JC, et al. (2006) A double-blind randomized controlled trial of antenatal mebendazole to reduce low birthweight in a hookworm-endemic area of Peru. Trop Med Int Health11: 1485–1495. 17002722
26. Blouin B, Penny ME, Maheu-Giroux M, Casapia M, Aguilar E, et al. (2013) Timing of umbilical cord-clamping and infant anaemia: the role of maternal anaemia. Paediatr Int Child Health33: 79–85. doi: 10.1179/2046905512Y.000000003623925280
27. Efird J, (2011) Blocked randomization with randomly selected block sizes. International journal of environmental research and public health8: 15–20. doi: 10.3390/ijerph801001521318011
28. de Onis M, Onyango AW, Van den Broeck J, Chumlea WC, Martorell R, (2004) Measurement and standardization protocols for anthropometry used in the construction of a new international growth reference. Food Nutr Bull25: S27–36. 15069917
29. WHO Multicentre Growth Reference Study Group (2006) Reliability of anthropometric measurements in the WHO Multicentre Growth Reference Study. Acta Paediatr Suppl450: 38–46. 16817677
30. Ulijaszek SJ, Kerr DA, (1999) Anthropometric measurement error and the assessment of nutritional status. Br J Nutr82: 165–177. 10655963
31. Montresor A, Crompton DW, Bundy DAP, Hall A, Savioli L (1998) Guidelines for the evaluation of soil-transmitted helminthiasis and schistosomiasis at community level—A guide for managers of control programmes. Geneva, Switzerland: World Health Organization—WHO/CTD/SIP/98.1. 45 p.
32. Tarafder MR, Carabin H, Joseph L, Balolong E, Jr.Olveda R, et al. (2010) Estimating the sensitivity and specificity of Kato-Katz stool examination technique for detection of hookworms, Ascaris lumbricoides and Trichuris trichiura infections in humans in the absence of a 'gold standard'. Int J Parasitol40: 399–404. doi: 10.1016/j.ijpara.2009.09.00319772859
33. WHO (2002) Prevention and Control of Schistosomiasis and Soil-Transmitted Helminthiasis. Geneva, Switzerland: Report of a WHO Expert Committee, Technical Report Series, No 912—World Health Organization. 63 p.
34. Gyorkos TW, Maheu-Giroux M, Blouin B, Casapia M, (2013) Impact of health education on soil-transmitted helminth infections in schoolchildren of the Peruvian Amazon: a cluster-randomized controlled trial. PLoS Negl Trop Dis7: e2397. doi: 10.1371/journal.pntd.000239724069469
35. Filmer D, Pritchett LH, (2001) Estimating wealth effects without expenditure data—or tears: an application to educational enrollments in states of India. Demography38: 115–132. 11227840
36. de Onis M, Garza C, Onyango AW, Rolland-Cachera MF, le Comité de nutrition de la Société française de pédiatrie (2009) WHO growth standards for infants and young children [in French]. Arch Pediatr16: 47–53. doi: 10.1016/j.arcped.2008.10.01019036567
37. Knopp S, Mgeni AF, Khamis IS, Steinmann P, Stothard JR, et al. (2008) Diagnosis of soil-transmitted helminths in the era of preventive chemotherapy: effect of multiple stool sampling and use of different diagnostic techniques. PLoS Negl Trop Dis2: e331. doi: 10.1371/journal.pntd.000033118982057
38. Montresor A, Stoltzfus RJ, Albonico M, Tielsch JM, Rice AL, et al. (2002) Is the exclusion of children under 24 months from anthelmintic treatment justifiable?Trans R Soc Trop Med Hyg96: 197–199. 12055814