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Volumn 2, Issue 10, 2015, Pages 978-983

Dimethyl fumarate inhibits integrin α4 expression in multiple sclerosis models

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTEGRIN; FINGOLIMOD; FUMARIC ACID DIMETHYL ESTER; TRANSCRIPTION FACTOR NRF2;

EID: 84955460360     PISSN: None     EISSN: 23289503     Source Type: Journal    
DOI: 10.1002/acn3.251     Document Type: Article
Times cited : (28)

References (20)
  • 1
    • 84878284582 scopus 로고    scopus 로고
    • BG-12 in multiple sclerosis
    • Phillips JT, Fox RJ. BG-12 in multiple sclerosis. Semin Neurol 2013;33:56–65.
    • (2013) Semin Neurol , vol.33 , pp. 56-65
    • Phillips, J.T.1    Fox, R.J.2
  • 2
    • 38149083332 scopus 로고    scopus 로고
    • Dimethylfumarate reduces leukocyte rolling in vivo through modulation of adhesion molecule expression
    • Rubant SA, Ludwig RJ, Diehl S, et al. Dimethylfumarate reduces leukocyte rolling in vivo through modulation of adhesion molecule expression. J Invest Dermatol 2008;128:326–331.
    • (2008) J Invest Dermatol , vol.128 , pp. 326-331
    • Rubant, S.A.1    Ludwig, R.J.2    Diehl, S.3
  • 3
    • 84927144781 scopus 로고    scopus 로고
    • PML in a patient without severe lymphocytopenia receiving dimethyl fumarate
    • Nieuwkamp DJ, Murk JL, van Oosten BW, et al. PML in a patient without severe lymphocytopenia receiving dimethyl fumarate. N Engl J Med 2015;372:1474–1476.
    • (2015) N Engl J Med , vol.372 , pp. 1474-1476
    • Nieuwkamp, D.J.1    Murk, J.L.2    van Oosten, B.W.3
  • 4
    • 84927155177 scopus 로고    scopus 로고
    • PML in a patient with lymphocytopenia treated with dimethyl fumarate
    • Rosenkranz T, Novas M, Terborg C. PML in a patient with lymphocytopenia treated with dimethyl fumarate. N Engl J Med 2015;372:1476–1478.
    • (2015) N Engl J Med , vol.372 , pp. 1476-1478
    • Rosenkranz, T.1    Novas, M.2    Terborg, C.3
  • 5
    • 33646373639 scopus 로고    scopus 로고
    • Natalizumab: immune effects and implications for therapy
    • Hauser SL, Weiner HL. Natalizumab: immune effects and implications for therapy. Ann Neurol 2006;59:731–732.
    • (2006) Ann Neurol , vol.59 , pp. 731-732
    • Hauser, S.L.1    Weiner, H.L.2
  • 6
    • 33746825429 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy revisited: has the disease outgrown its name?
    • Koralnik IJ. Progressive multifocal leukoencephalopathy revisited: has the disease outgrown its name? Ann Neurol 2006;60:162–173.
    • (2006) Ann Neurol , vol.60 , pp. 162-173
    • Koralnik, I.J.1
  • 7
    • 76049115808 scopus 로고    scopus 로고
    • Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis
    • Kihara Y, Matsushita T, Kita Y, et al. Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis. Proc Natl Acad Sci USA 2009;106:21807–21812.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 21807-21812
    • Kihara, Y.1    Matsushita, T.2    Kita, Y.3
  • 8
    • 84876119766 scopus 로고    scopus 로고
    • Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy
    • Groves A, Kihara Y, Chun J. Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy. J Neurol Sci 2013;328:9–18.
    • (2013) J Neurol Sci , vol.328 , pp. 9-18
    • Groves, A.1    Kihara, Y.2    Chun, J.3
  • 9
    • 84916898900 scopus 로고    scopus 로고
    • The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells
    • Turley AE, Zagorski JW, Rockwell CE. The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells. Cytokine 2015;71:289–295.
    • (2015) Cytokine , vol.71 , pp. 289-295
    • Turley, A.E.1    Zagorski, J.W.2    Rockwell, C.E.3
  • 10
    • 84928138268 scopus 로고    scopus 로고
    • B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity
    • Lehmann-Horn K, Sagan SA, Bernard CC, et al. B-cell very late antigen-4 deficiency reduces leukocyte recruitment and susceptibility to central nervous system autoimmunity. Ann Neurol 2015;77:902–908.
    • (2015) Ann Neurol , vol.77 , pp. 902-908
    • Lehmann-Horn, K.1    Sagan, S.A.2    Bernard, C.C.3
  • 11
    • 33745728404 scopus 로고    scopus 로고
    • How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis
    • Steinman L, Zamvil SS. How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis. Ann Neurol 2006;60:12–21.
    • (2006) Ann Neurol , vol.60 , pp. 12-21
    • Steinman, L.1    Zamvil, S.S.2
  • 12
    • 84941778910 scopus 로고    scopus 로고
    • Integrin alpha L controls the homing of regulatory T cells during CNS autoimmunity in the absence of integrin alpha 4
    • Glatigny S, Duhen R, Arbelaez C, et al. Integrin alpha L controls the homing of regulatory T cells during CNS autoimmunity in the absence of integrin alpha 4. Sci Rep 2015;5:7834.
    • (2015) Sci Rep , vol.5 , pp. 7834
    • Glatigny, S.1    Duhen, R.2    Arbelaez, C.3
  • 13
    • 84899722143 scopus 로고    scopus 로고
    • Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE
    • Chen H, Assmann JC, Krenz A, et al. Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE. J Clin Invest 2014;124:2188–2192.
    • (2014) J Clin Invest , vol.124 , pp. 2188-2192
    • Chen, H.1    Assmann, J.C.2    Krenz, A.3
  • 14
    • 84884339141 scopus 로고    scopus 로고
    • Clinical efficacy of BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: subgroup analyses of the DEFINE study
    • Bar-Or A, Gold R, Kappos L, et al. Clinical efficacy of BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: subgroup analyses of the DEFINE study. J Neurol 2013;260:2297–2305.
    • (2013) J Neurol , vol.260 , pp. 2297-2305
    • Bar-Or, A.1    Gold, R.2    Kappos, L.3
  • 15
    • 84884337463 scopus 로고    scopus 로고
    • Clinical efficacy of BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: subgroup analyses of the CONFIRM study
    • Hutchinson M, Fox RJ, Miller DH, et al. Clinical efficacy of BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: subgroup analyses of the CONFIRM study. J Neurol 2013;260:2286–2296.
    • (2013) J Neurol , vol.260 , pp. 2286-2296
    • Hutchinson, M.1    Fox, R.J.2    Miller, D.H.3
  • 16
    • 77951210258 scopus 로고    scopus 로고
    • Age-related differences in integrin expression in peripheral blood lymphocytes
    • Crooks CV, Cross ML, Wall CR. Age-related differences in integrin expression in peripheral blood lymphocytes. Immun Ageing 2010;7:5.
    • (2010) Immun Ageing , vol.7 , pp. 5
    • Crooks, C.V.1    Cross, M.L.2    Wall, C.R.3
  • 17
    • 24144441807 scopus 로고    scopus 로고
    • Downregulation of VLA-4 on T cells as a marker of long term treatment response to interferon beta-1a in MS
    • Soilu-Hanninen M, Laaksonen M, Hanninen A, et al. Downregulation of VLA-4 on T cells as a marker of long term treatment response to interferon beta-1a in MS. J Neuroimmunol 2005. 167:175–182.
    • (2005) J Neuroimmunol , vol.167 , pp. 175-182
    • Soilu-Hanninen, M.1    Laaksonen, M.2    Hanninen, A.3
  • 18
    • 0035052096 scopus 로고    scopus 로고
    • Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis
    • Theien BE, Vanderlugt CL, Eagar TN, et al. Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis. J Clin Invest 2001;107:995–1006.
    • (2001) J Clin Invest , vol.107 , pp. 995-1006
    • Theien, B.E.1    Vanderlugt, C.L.2    Eagar, T.N.3
  • 19
    • 84925535538 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy after interferon beta-1a monotherapy
    • Lehmann HC, Kruger K, Fink GR, Schroeter M. Progressive multifocal leukoencephalopathy after interferon beta-1a monotherapy. J Neurol 2015;262:771–773.
    • (2015) J Neurol , vol.262 , pp. 771-773
    • Lehmann, H.C.1    Kruger, K.2    Fink, G.R.3    Schroeter, M.4
  • 20
    • 0027529932 scopus 로고
    • Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma
    • Baron JL, Madri JA, Ruddle NH, et al. Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J Exp Med 1993;177:57–68.
    • (1993) J Exp Med , vol.177 , pp. 57-68
    • Baron, J.L.1    Madri, J.A.2    Ruddle, N.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.