Recent research progress and potential uses of the amphibian xenopus as a biomedical and immunological model system

Resources

Volumn 2, Issue 3, 2013, Pages 167-183

  Edholm, Eva Stina ^a   Robert, Jacques ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Biomedical model; Transgenesis; Xenopus

Indexed keywords

EID: 84955398135     PISSN: None     EISSN: 20799276     Source Type: Journal    
DOI: 10.3390/resources2030167     Document Type: Review

References (63)

1. Robert, J., Ohta, Y. Comparative and developmental study of the immune system in Xenopus. Dev. Dyn. 2009, 238, 1249-1270.
2. Du Pasquier, L., Schwager, J., Flajnik, M.F. The immune system of Xenopus. Annu. Rev. Immunol. 1989, 7, 251-275.
3. Khokha, M.K. Xenopus white papers and resources: Folding functional genomics and genetics into the frog. Genesis 2012, 50, 133-142.
4. Hellsten, U., Harland, R.M., Gilchrist, M.J., Hendrix, D., Jurka, J., Kapitonov, V., Ovcharenko, I., Putnam, N.H., Shu, S., Taher, L., et al. The genome of the western clawed frog Xenopus tropicalis. Science 2010, 328, 633-636.
5. Xenopus laevis Genome Resources Web Page. Available online: http://www.xenbase.org/genomes/ static/laevis.jsp (accessed on 9 July 2013).
6. University of Rochester Medical Center Web Page. Xenopus laevis Research Resource for Immunobiology. Available online: http://www.urmc.rochester.edu/mbi/resources/Xenopus (accessed on 9 July 2013).
7. Hsu, E. Mutation, selection, and memory in B lymphocytes of exothermic vertebrates. Immunol. Rev. 1998, 162, 25-36.
8. Du Pasquier, L., Robert, J., Courtet, M., Mussmann, R. B-cell development in the amphibian Xenopus. Immunol. Rev. 2000, 175, 201-213.
9. Barlow, E.H., Cohen, N. The thymus dependency of transplantation allotolerance in the metamorphosing frog Xenopus laevis. Transplantation 1983, 35, 612-619.
10. Nedelkovska, H., Robert, J. Comparative Study of Skin Graft Tolerance and Rejection in the Frog Xenopus laevis. In Skin Grafts-Indications, Applications and Current Research; Spear, S., Ed., InTech: New York, NY, USA, 2011. Available online: http://www.intechopen.com/books/skingrafts-indications-applications-and-current-research/comparative-study-of-skin-graft-tolerance-andrejection-in-the-frog-Xenopus-laevis (accessed on 10 July 2013).
11. Chardonnens, X., Du Pasquier, L. Induction of skin allograft tolerance during metamorphosis of the toad Xenopus laevis: A possible model for studying generation of self tolerance to histocompatibility antigens. Eur. J. Immunol. 1973, 3, 569-573.
12. Horton, J.D., Horton, T.L., Ritchie, P. Incomplete tolerance induced in Xenopus by larval tissue allografting: Evidence from immunohistology and mixed leucocyte culture. Dev. Comp. Immunol. 1993, 17, 249-262.
13. Turpen, J.B., Smith, P.B. Precursor immigration and thymocyte succession during larval development and metamorphosis in Xenopus. J. Immunol. 1989, 142, 41-47.
14. Flajnik, M.F., Kaufman, J.F., Hsu, E., Manes, M., Parisot, R., Du Pasquier, L. Major histocompatibility complex-encoded class I molecules are absent in immunologically competent Xenopus before metamorphosis. J. Immunol. 1986, 137, 3891-3899.
15. Salter-Cid, L., Nonaka, M., Flajnik, M.F. Expression of MHC class Ia and class Ib during ontogeny: High expression in epithelia and coregulation of class Ia and lmp7 genes. J. Immunol. 1998, 160, 2853-2861.
16. Rollins-Smith, L.A., Flajnik, M.F., Blair, P.J., Davis, A.T., Green, W.F. Involvement of thyroid hormones in the expression of MHC class I antigens during ontogeny in Xenopus. Dev. Immunol. 1997, 5, 133-144.
17. Du Pasquier, L., Flajnik, M.F. Expression of MHC class II antigens during Xenopus development. Dev. Immunol. 1990, 1, 85-95.
18. Horton, J.D., Horton, T.L., Dzialo, R., Gravenor, I., Minter, R., Ritchie, P., Gartland, L., Watson, M.D., Cooper, M.D. T-cell and natural killer cell development in thymectomized Xenopus. Immunol. Rev. 1998, 166, 245-258.
19. Robert, J., Gantress, J., Cohen, N., Maniero, G.D. Xenopus as an experimental model for studying evolution of hsp-Immune system interactions. Methods 2004, 32, 42-53.
20. Du Pasquier, L., Chardonnens, C. Genetic aspects of the tolerance to allografts induced at metamorphosis in the toad Xenopus laevis. Immunogenetics 1975, 2, 431-440.
21. Tochinai, S.K., Katagiri, C. Complete abrogation of immune responses to skin allografts and rabbit erythrocytes in the early thymectomized Xenopus. Dev. Growth Differ. 1975, 17, 383-394.
22. Xenbase Home Page. Available online: http://www.xenbase.org (accessed on 9 July 2013).
23. Kobel, H.R., Du Pasquier, L. Production of large clones of histocompatible, fully identical clawed toads (Xenopus). Immunogenetics 1975, 2, 7-91.
24. Nedelkovska, H., Cruz-Luna, T., McPherson, P., Robert, J. Comparative in vivo study of gp96 adjuvanticity in the frog Xenopus laevis. J. Vis. Exp. 2010, 43, 2026:1-2026:5.
25. Robert, J., Cohen, N. Evolution of immune surveillance and tumor immunity: Studies in Xenopus. Immunol. Rev. 1998, 166, 231-243.
26. Goyos, A., Robert, J. Tumorigenesis and anti-tumor immune responses in Xenopus. Front. Biosci. 2009, 14, 167-176.
27. Du Pasquier, L., Robert, J. In vitro growth of thymic tumor cell lines from Xenopus. Dev. Immunol. 1992, 2, 295-307.
28. Robert, J., Guiet, C., Du Pasquier, L. Lymphoid tumors of Xenopus laevis with different capacities for growth in larvae and adults. Dev. Immunol. 1994, 3, 297-307.
29. Robert, J., Cohen, N. Ontogeny of CTX expression in Xenopus. Dev. Comp. Immunol. 1998, 22, 605-612.
30. Robert, J., Guiet, C., Du Pasquier, L. Ontogeny of the alloimmune response against a transplanted tumor in Xenopus laevis. Differentiation 1995, 59, 135-144.
31. Goyos, A., Guselnikov, S., Chida, A.S., Sniderhan, L.F., Maggirwar, S.B., Nedelkovska, H., Robert, J. Involvement of nonclassical MHC class Ib molecules in heat shock protein-mediated anti-tumor responses. Eur. J. Immunol. 2007, 37, 1494-1501.
32. Goyos, A., Ohta, Y., Guselnikov, S., Robert, J. Novel nonclassical MHC class Ib genes associated with CD8 T cell development and thymic tumors. Mol. Immunol. 2009, 46, 1775-1786.
33. Zitvogel, L., Tesniere, A., Kroemer, G. Cancer despite immunosurveillance: Immunoselection and immunosubversion. Nat. Rev. Immunol. 2006, 6, 715-727.
34. Yie, S.M., Yang, H., Ye, S.R., Li, K., Dong, D.D., Lin, X.M. Expression of human leucocyte antigen G (HLA-G) is associated with prognosis in non-small cell lung cancer. Lung Cancer 2007, 58, 267-274.
35. De Kruijf, E.M., Sajet, A., van Nes, J.G., Natanov, R., Putter, H., Smit, V.T., Liefers, G.J., van den Elsen, P.J., van de Velde, C.J., Kuppen, P.J. HLA-E and HLA-G expression in classical HLA class I-negative tumors is of prognostic value for clinical outcome of early breast cancer patients. J. Immunol. 2010, 185, 7452-7459.
36. Chesneau, A., Sachs, L.M., Chai, N., Chen, Y., Du Pasquier, L., Loeber, J., Pollet, N., Reilly, M., Weeks, D.L., Bronchain, O.J. Transgenesis procedures in Xenopus. Biol. Cell 2008, 100, 503-521.
37. Kroll, K.L., Amaya, E. Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Development 1996, 122, 3173-3183.
38. Amaya, E., Kroll, K.L. A method for generating transgenic frog embryos. Methods Mol. Biol. 1999, 97, 393-414.
39. Allen, B.G., Weeks, D.L. Transgenic Xenopus laevis embryos can be generated using phiC31 integrase. Nat. Methods 2005, 2, 975-979.
40. Sinzelle, L., Vallin, J., Coen, L., Chesneau, A., Du Pasquier, D., Pollet, N., Demeneix, B., Mazabraud, A. Generation of trangenic Xenopus laevis using the Sleeping Beauty transposon system. Transgenic Res. 2006, 15, 751-760.
41. Ogino, H., McConnell, W.B., Grainger, R.M. High-throughput transgenesis in Xenopus using I-SceI meganuclease. Nat. Protoc. 2006, 1, 1703-1710.
42. Ogino, H., McConnell, W.B., Grainger, R.M. Highly efficient transgenesis in Xenopus tropicalis using I-SceI meganuclease. Mech. Dev. 2006, 123, 103-113.
43. Pan, F.C., Chen, Y., Loeber, J., Henningfeld, K., Pieler, T. I-SceI meganuclease-mediated transgenesis in Xenopus. Dev. Dyn. 2006, 235, 247-252.
44. Allen, B.G., Weeks, D.L. Bacteriophage phiC31 integrase mediated transgenesis in Xenopus laevis for protein expression at endogenous levels. Methods Mol. Biol. 2009, 518, 113-122.
45. Groth, A.C., Olivares, E.C., Thyagarajan, B., Calos, M.P. A phage integrase directs efficient site-specific integration in human cells. Proc. Natl. Acad. Sci. USA 2000, 97, 5995-6000.
46. Yergeau, D.A., Kelley, C.M., Zhu, H., Kuliyev, E., Mead, P.E. Transposon transgenesis in Xenopus. Methods 2010, 51, 92-100.
47. Hamlet, M.R., Yergeau, D.A., Kuliyev, E., Takeda, M., Taira, M., Kawakami, K., Mead, P.E. Tol2 transposon-mediated transgenesis in Xenopus tropicalis. Genesis 2006, 44, 438-445.
48. Miskey, C., Izsvak, Z., Plasterk, R.H., Ivics, Z. The Frog Prince: A reconstructed transposon from Rana pipiens with high transpositional activity in vertebrate cells. Nucleic Acids Res. 2003, 31, 6873-6881.
49. Nedelkovska, H., Robert, J. Optimized transgenesis in Xenopus laevis/gilli isogenetic clones for immunological studies. Genesis 2012, 50, 300-306.
50. Sifuentes-Romero, I., Milton, S.L., Garcia-Gasca, A. Post-transcriptional gene silencing by RNA interference in non-mammalian vertebrate systems: Where do we stand? Mutat. Res. 2011, 728, 158-171.
51. Lei, Y., Guo, X., Liu, Y., Cao, Y., Deng, Y., Chen, X., Cheng, C.H., Dawid, I.B., Chen, Y., Zhao, H. Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proc. Natl. Acad. Sci. USA 2012, 109, 17484-17489.
52. Ishibashi, S., Cliffe, R., Amaya, E. Highly efficient bi-allelic mutation rates using TALENs in Xenopus tropicalis. Biol. Open 2012, 1, 1273-1276.
53. Young, J.J., Cherone, J.M., Doyon, Y., Ankoudinova, I., Faraji, F.M., Lee, A.H., Ngo, C., Guschin, D.Y., Paschon, D.E., Miller, J.C., et al. Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. Proc. Natl. Acad. Sci. USA 2011, 108, 7052-7057.
54. Nedelkovska, H., Edholm, E.S., Haynes, N., Robert, J. Effective RNAi-mediated beta2-microglobulin loss of function by transgenesis in Xenopus laevis. Biol. Open 2013, 2, 335-342.
55. National Center for Biotechnology Information (NCBI) Web Page. UniGene. Available online: http://www.ncbi.nlm.nih.gov/unigene (accessed on 9 July 2013).
56. Kobel, H.R., Tinsley, R.C. Xenopus Species and Ecology 2: The Extant Species. In The Biology of Xenopus; Clarendon: Oxford, UK, 1996; pp. 9-31.
57. Evans, B.J. Genome evolution and speciation genetics of clawed frogs (Xenopus and Silurana). Front. Biosci. 2008, 13, 4687-4706.
58. Kobel, H.R., Du Pasquier, L. Genetics of polyploidy Xenopus. Trends Genet. 1986, 2, 310-315.
59. Flajnik, M.F., Kasahara, M. Comparative genomics of the MHC: Glimpses into the evolution of the adaptive immune system. Immunity 2001, 15, 351-362.
60. Hellsten, U., Khokha, M.K., Grammer, T.C., Harland, R.M., Richardson, P., Rokhsar, D.S. Accelerated gene evolution and subfunctionalization in the pseudotetraploid frog Xenopus laevis. BMC Biol. 2007, 5, doi:10.1186/1741-7007-5-31.
61. Hughes, M.K., Hughes, A.L. Evolution of duplicate genes in a tetraploid animal, Xenopus laevis. Mol. Biol. Evol. 1993, 10, 1360-1369.
62. Shum, B.P., Avila, D., Du Pasquier, L., Kasahara, M., Flajnik, M.F. Isolation of a classical MHC class I cDNA from an amphibian. Evidence for only one class I locus in the Xenopus MHC. J. Immunol. 1993, 151, 5376-5386.
63. Courtet, M., Flajnik, M., Du Pasquier, L. Major histocompatibility complex and immunoglobulin loci visualized by in situ hybridization on Xenopus chromosomes. Dev. Comp. Immunol. 2001, 25, 149-157.