Impact of severe ADAMTS13 deficiency on clinical presentation and outcomes in patients with thrombotic microangiopathies: The experience of the Harvard TMA Research Collaborative

British Journal of Haematology

Volumn 171, Issue 5, 2015, Pages 836-844

  Bendapudi, Pavan K ^a,b   Li, Ang ^a,b   Hamdan, Ayad ^b,c   Uhl, Lynne ^b,c   Kaufman, Richard ^b,d   Stowell, Christopher ^a,b   Dzik, Walter ^a,b   Makar, Robert S ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

ADAMTS13; Autoimmune thrombotic thrombocytopenic purpura; Plasma exchange; Thrombotic microangiopathy

Indexed keywords

FRESH FROZEN PLASMA; VON WILLEBRAND FACTOR CLEAVING PROTEINASE; ADAM PROTEIN; ADAMTS13 PROTEIN, HUMAN;

ADULT; AGE DISTRIBUTION; ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; CRYOPRECIPITATE; DISEASE ASSOCIATION; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; ENZYME ANALYSIS; ENZYME DEFICIENCY; FEMALE; HUMAN; LABORATORY TEST; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PLASMAPHERESIS; PRIORITY JOURNAL; SEX DIFFERENCE; SURVIVAL TIME; THROMBOTIC THROMBOCYTOPENIC PURPURA; TREATMENT RESPONSE; VON WILLEBRAND FACTOR CLEAVING PROTEINASE DEFICIENCY; AGED; CLINICAL TRIAL; DEFICIENCY; MIDDLE AGED; MULTICENTER STUDY; PROCEDURES; PURPURA, THROMBOTIC THROMBOCYTOPENIC; THROMBOTIC MICROANGIOPATHIES; TREATMENT OUTCOME;

ADAM PROTEINS; ADULT; AGED; FEMALE; HUMANS; LENGTH OF STAY; MALE; MIDDLE AGED; PLASMA EXCHANGE; PURPURA, THROMBOTIC THROMBOCYTOPENIC; THROMBOTIC MICROANGIOPATHIES; TREATMENT OUTCOME;

EID: 84955361858     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13658     Document Type: Article

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