Suppression of transcriptional drift extends C. Elegans lifespan by postponing the onset of mortality

eLife

Volumn 4, Issue DECEMBER2015, 2015, Pages

  Rangaraju, Sunitha ^a   Solis, Gregory M ^a   Thompson, Ryan C ^a   Gomez Amaro, Rafael L ^a   Kurian, Leo ^b   Encalada, Sandra E ^a   Niculescu, Alexander B ^c   Salomon, Daniel R ^a   Petrascheck, Michael ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MIANSERIN; PROTEASOME; SEROTONIN RECEPTOR; TRANSCRIPTOME; SEROTONIN ANTAGONIST; SEROTONIN;

ADULT; AGING; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; GENE EXPRESSION; GENE ONTOLOGY; GENE SEQUENCE; GENETIC DRIFT; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LIFESPAN; LONGEVITY; MORTALITY; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTIONAL DRIFT; ANIMAL; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; PHYSIOLOGY; AGE; AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SIGNAL TRANSDUCTION; STOICHIOMETRY; SURVIVAL; UPREGULATION; VERY ELDERLY;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LONGEVITY; MIANSERIN; SEROTONIN ANTAGONISTS; TRANSCRIPTION, GENETIC;

EID: 84955283754     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.08833.001     Document Type: Article

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