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Volumn 46, Issue 1, 2016, Pages 112-124

Genetic associations with viral respiratory illnesses and asthma control in children

Author keywords

Allergic sensitization; Asthma; Children; Cold symptoms; Genetic association; Human rhinovirus; Viral respiratory illness; Wheezing

Indexed keywords

ARTICLE; ASTHMA; AUTUMN; CHILD; COHORT ANALYSIS; DDX58 GENE; DISEASE EXACERBATION; DISEASE SEVERITY; EIF2AK2 GENE; FEMALE; GENE; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; JAK2 GENE; MAJOR CLINICAL STUDY; MALE; MX1 GENE; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STAT4 GENE; VDR GENE; VIRAL RESPIRATORY TRACT INFECTION; WHEEZING; AGE; ALLELE; COMPLICATION; DISEASE COURSE; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOTYPE; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PROGNOSIS; REPRODUCIBILITY; RESPIRATORY TRACT INFECTIONS; VIROLOGY;

EID: 84955283551     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.12642     Document Type: Article
Times cited : (35)

References (57)
  • 1
    • 0022589125 scopus 로고
    • Risk of primary infection and reinfection with respiratory syncytial virus
    • Glezen WP, Taber LH, Frank AL, Kasel JA. Risk of primary infection and reinfection with respiratory syncytial virus. Am J Dis Child 1986; 140:543-6.
    • (1986) Am J Dis Child , vol.140 , pp. 543-546
    • Glezen, W.P.1    Taber, L.H.2    Frank, A.L.3    Kasel, J.A.4
  • 3
    • 77950988249 scopus 로고    scopus 로고
    • The role of rhinovirus infections in the development of early childhood asthma
    • Jackson DJ. The role of rhinovirus infections in the development of early childhood asthma. Curr Opin Allergy Clin Immunol 2010; 10:133-8.
    • (2010) Curr Opin Allergy Clin Immunol , vol.10 , pp. 133-138
    • Jackson, D.J.1
  • 4
    • 79959354875 scopus 로고    scopus 로고
    • Rhinoviruses, allergic inflammation, and asthma
    • Gavala ML, Bertics PJ, Gern JE. Rhinoviruses, allergic inflammation, and asthma. Immunol Rev 2011; 242:69-90.
    • (2011) Immunol Rev , vol.242 , pp. 69-90
    • Gavala, M.L.1    Bertics, P.J.2    Gern, J.E.3
  • 5
    • 52749097374 scopus 로고    scopus 로고
    • Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children
    • Jackson DJ, Gangnon RE, Evans MD et al. Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children. Am J Respir Crit Care Med 2008; 178:667-72.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 667-672
    • Jackson, D.J.1    Gangnon, R.E.2    Evans, M.D.3
  • 7
    • 80052235990 scopus 로고    scopus 로고
    • Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthma
    • Guilbert TW, Singh AM, Danov Z et al. Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthma. J Allergy Clin Immunol 2011; 128:532.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 532
    • Guilbert, T.W.1    Singh, A.M.2    Danov, Z.3
  • 9
    • 0028990124 scopus 로고
    • Community study of role of viral infections in exacerbations of asthma in 9-11 year-old children
    • Johnston SL, Pattemore PK, Sanderson G et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year-old children. Br Med J 1995; 310:1225-9.
    • (1995) Br Med J , vol.310 , pp. 1225-1229
    • Johnston, S.L.1    Pattemore, P.K.2    Sanderson, G.3
  • 10
    • 3142707105 scopus 로고    scopus 로고
    • Cytokine response patterns, exposure to viruses, and respiratory infections in the first year of life
    • Copenhaver CC, Gern JE, Li ZH et al. Cytokine response patterns, exposure to viruses, and respiratory infections in the first year of life. Am J Respir Crit Care Med 2004; 170:175-80.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 175-180
    • Copenhaver, C.C.1    Gern, J.E.2    Li, Z.H.3
  • 11
    • 84875932548 scopus 로고    scopus 로고
    • Rhinovirus wheezing illness and genetic risk of childhood-onset asthma
    • Caliskan M, Bochkov YA, Kreiner-Moller E et al. Rhinovirus wheezing illness and genetic risk of childhood-onset asthma. N Engl J Med 2013; 368:1398-407.
    • (2013) N Engl J Med , vol.368 , pp. 1398-1407
    • Caliskan, M.1    Bochkov, Y.A.2    Kreiner-Moller, E.3
  • 13
    • 73349104638 scopus 로고    scopus 로고
    • Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses
    • Wang Q, Nagarkar DR, Bowman ER et al. Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses. J Immunol 2009; 183:6989-97.
    • (2009) J Immunol , vol.183 , pp. 6989-6997
    • Wang, Q.1    Nagarkar, D.R.2    Bowman, E.R.3
  • 14
    • 79251492014 scopus 로고    scopus 로고
    • Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium
    • Slater L, Bartlett NW, Haas JJ et al. Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium. PLoS Pathog 2010; 6:e1001178.
    • (2010) PLoS Pathog , vol.6 , pp. e1001178
    • Slater, L.1    Bartlett, N.W.2    Haas, J.J.3
  • 16
    • 84969416970 scopus 로고    scopus 로고
    • Increased H1N1 infection rate in asthmatic children
    • Kloepfer KM, Olenec JP, Lee W et al. Increased H1N1 infection rate in asthmatic children. J Allergy Clin Immunol 2011; 127:1275-9.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1275-1279
    • Kloepfer, K.M.1    Olenec, J.P.2    Lee, W.3
  • 17
    • 77951665666 scopus 로고    scopus 로고
    • Weekly monitoring of children with asthma for infections and illness during common cold seasons
    • e1001.
    • Olenec JP, Kim WK, Lee WM et al. Weekly monitoring of children with asthma for infections and illness during common cold seasons. J Allergy Clin Immunol 2010; 125:1001-6. e1001.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 1001-1006
    • Olenec, J.P.1    Kim, W.K.2    Lee, W.M.3
  • 18
    • 0038548251 scopus 로고    scopus 로고
    • Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: results of 2 double-blind, randomized, placebo-controlled trials
    • Pleconaril Respiratory Infection Study G.
    • Hayden FG, Herrington DT, Coats TL et al., Pleconaril Respiratory Infection Study G. Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: results of 2 double-blind, randomized, placebo-controlled trials. Clin Infect Dis 2003; 36:1523-32.
    • (2003) Clin Infect Dis , vol.36 , pp. 1523-1532
    • Hayden, F.G.1    Herrington, D.T.2    Coats, T.L.3
  • 20
    • 34548087592 scopus 로고    scopus 로고
    • High-throughput, sensitive, and accurate multiplex PCR-microsphere flow cytometry system for large-scale comprehensive detection of respiratory viruses
    • Lee WM, Grindle K, Pappas T et al. High-throughput, sensitive, and accurate multiplex PCR-microsphere flow cytometry system for large-scale comprehensive detection of respiratory viruses. J Clin Microbiol 2007; 45:2626-34.
    • (2007) J Clin Microbiol , vol.45 , pp. 2626-2634
    • Lee, W.M.1    Grindle, K.2    Pappas, T.3
  • 21
    • 41549169185 scopus 로고    scopus 로고
    • A diverse group of previously unrecognized human rhinoviruses are common causes of respiratory illnesses in infants
    • Lee WM, Kiesner C, Pappas T et al. A diverse group of previously unrecognized human rhinoviruses are common causes of respiratory illnesses in infants. PLoS ONE 2007; 2:e966.
    • (2007) PLoS ONE , vol.2 , pp. e966
    • Lee, W.M.1    Kiesner, C.2    Pappas, T.3
  • 23
    • 84891372721 scopus 로고    scopus 로고
    • A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations
    • Bonnelykke K, Sleiman P, Nielsen K et al. A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nat Genet 2014; 46:51-5.
    • (2014) Nat Genet , vol.46 , pp. 51-55
    • Bonnelykke, K.1    Sleiman, P.2    Nielsen, K.3
  • 24
    • 84892392750 scopus 로고    scopus 로고
    • Deep phenotyping of the unselected COPSAC2010 birth cohort study
    • Bisgaard H, Vissing NH, Carson CG et al. Deep phenotyping of the unselected COPSAC2010 birth cohort study. Clin Exp Allergy 2013; 43:1384-94.
    • (2013) Clin Exp Allergy , vol.43 , pp. 1384-1394
    • Bisgaard, H.1    Vissing, N.H.2    Carson, C.G.3
  • 25
    • 0036964029 scopus 로고    scopus 로고
    • The childhood origins of asthma (COAST) study
    • Lemanske RF. The childhood origins of asthma (COAST) study. Pediatr Allergy Immunol 2002; 13:38-43.
    • (2002) Pediatr Allergy Immunol , vol.13 , pp. 38-43
    • Lemanske, R.F.1
  • 26
    • 80052263017 scopus 로고    scopus 로고
    • IFNG genotype and sex interact to influence risk of childhood asthma
    • Loisel DA, Zheng T, Tisler C et al. IFNG genotype and sex interact to influence risk of childhood asthma. J Allergy Clin Immunol 2011; 128:524.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 524
    • Loisel, D.A.1    Zheng, T.2    Tisler, C.3
  • 27
    • 84865712382 scopus 로고    scopus 로고
    • Annotation of functional variation in personal genomes using RegulomeDB
    • Boyle AP, Hong EL, Hariharan M et al. Annotation of functional variation in personal genomes using RegulomeDB. Genome Res 2012; 22:1790-7.
    • (2012) Genome Res , vol.22 , pp. 1790-1797
    • Boyle, A.P.1    Hong, E.L.2    Hariharan, M.3
  • 28
    • 84858779229 scopus 로고    scopus 로고
    • HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
    • Ward LD, Kellis M. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res 2012; 40:D930-4.
    • (2012) Nucleic Acids Res , vol.40 , pp. D930-D934
    • Ward, L.D.1    Kellis, M.2
  • 29
    • 77951640946 scopus 로고    scopus 로고
    • A method and server for predicting damaging missense mutations
    • Adzhubei IA, Schmidt S, Peshkin L et al. A method and server for predicting damaging missense mutations. Nat Methods 2010; 7:248-9.
    • (2010) Nat Methods , vol.7 , pp. 248-249
    • Adzhubei, I.A.1    Schmidt, S.2    Peshkin, L.3
  • 30
    • 34547458187 scopus 로고    scopus 로고
    • Polymorphisms of STAT-6, STAT-4 and IFN-gamma genes and the risk of asthma in Chinese population
    • Li Y, Wu B, Xiong H, Zhu C, Zhang L. Polymorphisms of STAT-6, STAT-4 and IFN-gamma genes and the risk of asthma in Chinese population. Respir Med 2007; 101:1977-81.
    • (2007) Respir Med , vol.101 , pp. 1977-1981
    • Li, Y.1    Wu, B.2    Xiong, H.3    Zhu, C.4    Zhang, L.5
  • 31
    • 20944440739 scopus 로고    scopus 로고
    • Association analysis of signal transducer and activator of transcription 4 (STAT4) polymorphisms with asthma
    • Park BL, Cheong HS, Kim LH et al. Association analysis of signal transducer and activator of transcription 4 (STAT4) polymorphisms with asthma. J Hum Genet 2005; 50:133-8.
    • (2005) J Hum Genet , vol.50 , pp. 133-138
    • Park, B.L.1    Cheong, H.S.2    Kim, L.H.3
  • 32
    • 19944427870 scopus 로고    scopus 로고
    • Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes
    • Pykalainen M, Kinos R, Valkonen S et al. Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes. J Allergy Clin Immunol 2005; 115:80-7.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 80-87
    • Pykalainen, M.1    Kinos, R.2    Valkonen, S.3
  • 33
    • 15844396183 scopus 로고    scopus 로고
    • Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
    • Thierfelder WE, van Deursen JM, Yamamoto K et al. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells. Nature 1996; 382:171-4.
    • (1996) Nature , vol.382 , pp. 171-174
    • Thierfelder, W.E.1    van Deursen, J.M.2    Yamamoto, K.3
  • 34
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
    • Kaplan MH, Sun YL, Hoey T, Grusby MJ. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 1996; 382:174-7.
    • (1996) Nature , vol.382 , pp. 174-177
    • Kaplan, M.H.1    Sun, Y.L.2    Hoey, T.3    Grusby, M.J.4
  • 35
    • 29544445309 scopus 로고    scopus 로고
    • Bidirectional interactions between viral respiratory illnesses and cytokine responses in the first year of life
    • Gern JE, Brooks GD, Meyer P et al. Bidirectional interactions between viral respiratory illnesses and cytokine responses in the first year of life. J Allergy Clin Immunol 2006; 117:72-8.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 72-78
    • Gern, J.E.1    Brooks, G.D.2    Meyer, P.3
  • 36
    • 0034521180 scopus 로고    scopus 로고
    • Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infection
    • Gern JE, Vrtis R, Grindle KA, Swenson C, Busse WW. Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infection. Am J Respir Crit Care Med 2000; 162:2226-31.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 2226-2231
    • Gern, J.E.1    Vrtis, R.2    Grindle, K.A.3    Swenson, C.4    Busse, W.W.5
  • 37
    • 84896742056 scopus 로고    scopus 로고
    • Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
    • Fairfax BP, Humburg P, Makino S et al. Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Science 2014; 343:1246949.
    • (2014) Science , vol.343 , pp. 1246949
    • Fairfax, B.P.1    Humburg, P.2    Makino, S.3
  • 38
    • 84890476408 scopus 로고    scopus 로고
    • Mx proteins: antiviral gatekeepers that restrain the uninvited
    • Verhelst J, Hulpiau P, Saelens X. Mx proteins: antiviral gatekeepers that restrain the uninvited. Microbiol Mol Biol Rev 2013; 77:551-66.
    • (2013) Microbiol Mol Biol Rev , vol.77 , pp. 551-566
    • Verhelst, J.1    Hulpiau, P.2    Saelens, X.3
  • 39
    • 84901020479 scopus 로고    scopus 로고
    • A genetic model of differential susceptibility to human respiratory syncytial virus (RSV) infection
    • Ciencewicki JM, Wang X, Marzec J et al. A genetic model of differential susceptibility to human respiratory syncytial virus (RSV) infection. FASEB J 2014; 28:1947-56.
    • (2014) FASEB J , vol.28 , pp. 1947-1956
    • Ciencewicki, J.M.1    Wang, X.2    Marzec, J.3
  • 40
    • 79952103287 scopus 로고    scopus 로고
    • Gene-environment interactions in human disease: nuisance or opportunity?
    • Ober C, Vercelli D. Gene-environment interactions in human disease: nuisance or opportunity? Trends Genet 2011; 27:107-15.
    • (2011) Trends Genet , vol.27 , pp. 107-115
    • Ober, C.1    Vercelli, D.2
  • 42
    • 67349208909 scopus 로고    scopus 로고
    • Analyses of associations with asthma in four asthma population samples from Canada and Australia
    • Daley D, Lemire M, Akhabir L et al. Analyses of associations with asthma in four asthma population samples from Canada and Australia. Hum Genet 2009; 125:445-59.
    • (2009) Hum Genet , vol.125 , pp. 445-459
    • Daley, D.1    Lemire, M.2    Akhabir, L.3
  • 43
    • 84872613440 scopus 로고    scopus 로고
    • Association of vitamin D receptor gene polymorphisms with susceptibility to asthma in Tunisian children: a case control study
    • Maalmi H, Sassi FH, Berraies A, Ammar J, Hamzaoui K, Hamzaoui A. Association of vitamin D receptor gene polymorphisms with susceptibility to asthma in Tunisian children: a case control study. Hum Immunol 2013; 74:234-40.
    • (2013) Hum Immunol , vol.74 , pp. 234-240
    • Maalmi, H.1    Sassi, F.H.2    Berraies, A.3    Ammar, J.4    Hamzaoui, K.5    Hamzaoui, A.6
  • 44
    • 8444222000 scopus 로고    scopus 로고
    • Association of vitamin D receptor gene polymorphisms with childhood and adult asthma
    • Raby BA, Lazarus R, Silverman EK et al. Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. Am J Respir Crit Care Med 2004; 170:1057-65.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 1057-1065
    • Raby, B.A.1    Lazarus, R.2    Silverman, E.K.3
  • 45
    • 7044253544 scopus 로고    scopus 로고
    • Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy
    • Poon AH, Laprise C, Lemire M et al. Association of vitamin D receptor genetic variants with susceptibility to asthma and atopy. Am J Respir Crit Care Med 2004; 170:967-73.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 967-973
    • Poon, A.H.1    Laprise, C.2    Lemire, M.3
  • 46
    • 68149091687 scopus 로고    scopus 로고
    • Association study between vitamin D receptor gene polymorphisms and asthma in the Chinese Han population: a case-control study
    • Saadi A, Gao G, Li H, Wei C, Gong Y, Liu Q. Association study between vitamin D receptor gene polymorphisms and asthma in the Chinese Han population: a case-control study. BMC Med Genet 2009; 10:71.
    • (2009) BMC Med Genet , vol.10 , pp. 71
    • Saadi, A.1    Gao, G.2    Li, H.3    Wei, C.4    Gong, Y.5    Liu, Q.6
  • 47
    • 84856500098 scopus 로고    scopus 로고
    • Associations between genetic variants in vitamin D metabolism and asthma characteristics in young African Americans: a pilot study
    • Pillai DK, Iqbal SF, Benton AS et al. Associations between genetic variants in vitamin D metabolism and asthma characteristics in young African Americans: a pilot study. J Investig Med 2011; 59:938-46.
    • (2011) J Investig Med , vol.59 , pp. 938-946
    • Pillai, D.K.1    Iqbal, S.F.2    Benton, A.S.3
  • 48
    • 40549095701 scopus 로고    scopus 로고
    • Vitamin D receptor polymorphisms and the risk of acute lower respiratory tract infection in early childhood
    • Roth DE, Jones AB, Prosser C, Robinson JL, Vohra S. Vitamin D receptor polymorphisms and the risk of acute lower respiratory tract infection in early childhood. J Infect Dis 2008; 197:676-80.
    • (2008) J Infect Dis , vol.197 , pp. 676-680
    • Roth, D.E.1    Jones, A.B.2    Prosser, C.3    Robinson, J.L.4    Vohra, S.5
  • 49
    • 80051582182 scopus 로고    scopus 로고
    • Confirmation of an association between single nucleotide polymorphisms in the VDR gene with respiratory syncytial virus related disease in South African children
    • Kresfelder TL, Janssen R, Bont L, Venter M. Confirmation of an association between single nucleotide polymorphisms in the VDR gene with respiratory syncytial virus related disease in South African children. J Med Virol 2011; 83:1834-40.
    • (2011) J Med Virol , vol.83 , pp. 1834-1840
    • Kresfelder, T.L.1    Janssen, R.2    Bont, L.3    Venter, M.4
  • 50
    • 79961005836 scopus 로고    scopus 로고
    • Vitamin D binding protein variants associate with asthma susceptibility in the Chinese Han population
    • Li F, Jiang L, Willis-Owen SA, Zhang Y, Gao J. Vitamin D binding protein variants associate with asthma susceptibility in the Chinese Han population. BMC Med Genet 2011; 12:103.
    • (2011) BMC Med Genet , vol.12 , pp. 103
    • Li, F.1    Jiang, L.2    Willis-Owen, S.A.3    Zhang, Y.4    Gao, J.5
  • 52
    • 4344675303 scopus 로고    scopus 로고
    • Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene
    • Nejentsev S, Godfrey L, Snook H et al. Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene. Hum Mol Genet 2004; 13:1633-9.
    • (2004) Hum Mol Genet , vol.13 , pp. 1633-1639
    • Nejentsev, S.1    Godfrey, L.2    Snook, H.3
  • 53
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst J, Kheradpour P, Mikkelsen TS et al. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 2011; 473:43-9.
    • (2011) Nature , vol.473 , pp. 43-49
    • Ernst, J.1    Kheradpour, P.2    Mikkelsen, T.S.3
  • 54
    • 79956314622 scopus 로고    scopus 로고
    • Immune signaling by RIG-I-like receptors
    • Loo YM, Gale M. Immune signaling by RIG-I-like receptors. Immunity 2011; 34:680-92.
    • (2011) Immunity , vol.34 , pp. 680-692
    • Loo, Y.M.1    Gale, M.2
  • 55
    • 77956195791 scopus 로고    scopus 로고
    • A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells
    • Hu JZ, Nistal-Villan E, Voho A et al. A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells. J Immunol 2010; 185:424-32.
    • (2010) J Immunol , vol.185 , pp. 424-432
    • Hu, J.Z.1    Nistal-Villan, E.2    Voho, A.3
  • 56
    • 70449568252 scopus 로고    scopus 로고
    • Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response
    • Pothlichet J, Burtey A, Kubarenko AV et al. Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response. PLoS ONE 2009; 4:e7582.
    • (2009) PLoS ONE , vol.4 , pp. e7582
    • Pothlichet, J.1    Burtey, A.2    Kubarenko, A.V.3
  • 57
    • 80052832530 scopus 로고    scopus 로고
    • Genetics of sputum gene expression in chronic obstructive pulmonary disease
    • Qiu W, Cho MH, Riley JH et al. Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS ONE 2011; 6:e24395.
    • (2011) PLoS ONE , vol.6 , pp. e24395
    • Qiu, W.1    Cho, M.H.2    Riley, J.H.3


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