Unintentional Continuation of Medications Intended for Acute Illness After Hospital Discharge: A Population-Based Cohort Study

Journal of General Internal Medicine

Volumn 31, Issue 2, 2016, Pages 196-202

  Scales, Damon C ^a,b,c,d   Fischer, Hadas D ^c   Li, Ping ^c   Bierman, Arlene S ^b,c,d,g,h   Fernandes, Olavo ^d,h,i   Mamdani, Muhammad ^c,d,g,h   Rochon, Paula ^b,c,d,f   Urbach, David R ^c,d,h   Bell, Chaim M ^b,c,d,e  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c INSTITUTE FOR CLINICAL EVALUATIVE SCIENCES   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e MOUNT SINAI HOSPITAL   (United States)

^f WOMEN S COLLEGE HOSPITAL   (Canada)

^g ST MICHAEL'S HOSPITAL   (Canada)

^h UNIVERSITY OF TORONTO   (Canada)

ⁱ UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

aged; cohort studies; continuity of patient care; hospitalizations; medication errors; polypharmacy; prescriptions

Indexed keywords

BENZODIAZEPINE DERIVATIVE; BRONCHODILATING AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; NEUROLEPTIC AGENT; PROTON PUMP INHIBITOR; STEROID;

ACUTE DISEASE; AGED; ARTICLE; CANADA; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; FOLLOW UP; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT CARE; PRESCRIPTION; RISK FACTOR; FACTUAL DATABASE; MEDICATION ERROR; ONTARIO; POLYPHARMACY; SOCIOECONOMICS; STANDARDS; STATISTICS AND NUMERICAL DATA; VERY ELDERLY;

ACUTE DISEASE; AGED; AGED, 80 AND OVER; COHORT STUDIES; CONTINUITY OF PATIENT CARE; DATABASES, FACTUAL; DRUG PRESCRIPTIONS; FEMALE; HOSPITALIZATION; HUMANS; MALE; MEDICATION ERRORS; ONTARIO; PATIENT DISCHARGE; POLYPHARMACY; RISK FACTORS; SOCIOECONOMIC FACTORS;

EID: 84955170389     PISSN: 08848734     EISSN: 15251497     Source Type: Journal    
DOI: 10.1007/s11606-015-3501-5     Document Type: Article

References (37)

1. Cook RI, Render M, Woods DD. Gaps in the continuity of care and progress on patient safety. BMJ. 2000;320(7237):791–794.
2. van der Kam WJ, de Meyboom JB, Tromp TF, Moorman PW, van der Lei J. Effects of electronic communication between the GP and the pharmacist. The quality of medication data on admission and after discharge. Fam Pract. 2001;18(6):605–609.
3. van Walraven C, Seth R, Austin PC. A. L. Effect of discharge summary availability during post-discharge visits on hospital readmission. J Gen Intern Med. 2002;17(3):186–192.
4. van Walraven C, Mamdani M, Fang J. PC. A. Continuity of care and patient outcomes after hospital discharge. J Gen Intern Med. 2004;19(6):624–631.
5. Branger PJ, van der Wouden JC, Schudel BR. Electronic communication between providers of primary and secondary care. BMJ. 1992;305(6861):1068–1070.
6. van Walraven C. E. R. What is necessary for high-quality discharge summaries? Am J Med Qual. 1999;14(4):160–169.
7. van Walraven C, Laupacis A, Seth R, Wells GF. Dictated versus database-generated discharge summaries: a randomized clinical trial. CMAJ Can Med Assoc J. 1999;160(3):319–326.
8. van Walraven C. AL. W. Quality assessment of a discharge summary system. CMAJ Can Med Assoc J. 1995;152(9):1437–1442.
9. Kripalani S, LeFevre F, Phillips CO, Williams MV, Basaviah P, Baker DW. Deficits in communication and information transfer between hospital-based and primary care physicians: implications for patient safety and continuity of care 1. JAMA. 2007;297(8):831–841.
10. Kripalani S, Jackson AT, Schnipper JL, Coleman EA. Promoting effective transitions of care at hospital discharge: a review of key issues for hospitalists. [Review] [108 refs]. J Hospital Med (Online). 2007;2(5):314–323.
11. Institute for Health I. Getting Started Kit: Prevent Adverse Drug Events (Medication Reconciliation). 2005; http://www.ihi.org/resources/Pages/Tools/HowtoGuidePreventAdverseDrugEvents.aspx. Accessed July 31, 2015.
12. Schnipper JL, Hamann C, Ndumele CD, et al. Effect of an electronic medication reconciliation application and process redesign on potential adverse drug events: a cluster-randomized trial. Arch Intern Med. 2009;169(8):771–780.
13. Boockvar KS, Carlson LH, Giambanco V, Fridman B, Siu A. Medication reconciliation for reducing drug-discrepancy adverse events. Am J Geriatric Pharmacother. 2006;4(3):236–243.
14. Pronovost P, Weast B, Schwarz M, et al. Medication reconciliation: a practical tool to reduce the risk of medication errors. J Crit Care. 2003;18(4):201–205.
15. Cullen DJ, Sweitzer BJ, Bates DW, Burdick E, Edmondson A, Leape LL. Preventable adverse drug events in hospitalized patients: a comparative study of intensive care and general care units. Crit Care Med. 1997;25(8):1289–1297.
16. Rothschild JM, Landrigan CP, Cronin JW, et al. The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care. Crit Care Med. 2005;33(8):1694–1700.
17. Bell CM, Brener SS, Gunraj N, et al. Association of ICU or hospital admission with unintentional discontinuation of medications for chronic diseases 1. JAMA. 2011;306(8):840–847.
18. Bronskill SE, Gill SS, Paterson JM, Bell CM, Anderson GM, Rochon PA. Exploring variation in rates of polypharmacy across long term care homes. J Am Med Dir Assoc. 2012;13(3):309 e315–321.
19. Naylor CD, Anderson GM, Goel V. Patterns of health care in Ontario. Toronto: Institute for Clinical Evaluative Sciences; 1994.
20. Williams JI, Young W. A summary of studies on the quality of health care administrative databases in Canada. In: Goel V, Williams JI, Anderson GM, Blackerstein-Hersch P, Fooks C, Naylor CD, eds. Vol 2nd. Ottawa: Canadian Medical Association; 1996:339–345.
21. Juurlink D, Preyra C, Croxford R, et al. Canadian Institute for Health Information Discharge Abstract Database: A Validation Study. Toronto: Institute for Clinical Evaluative Sciences; 2006.
22. Sevransky JE, Levy MM, Marini JJ. Mechanical ventilation in sepsis-induced acute lung injury/acute respiratory distress syndrome: an evidence-based review. Crit Care Med. 2004;32(11 Suppl):S548–553.
23. Jacobi J, Fraser GL, Coursin DB, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med. 2002;30(1):119–141.
24. Heyland DK, Dhaliwal R, Drover JW, Gramlich L, Dodek P. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN. J Parenter Enter Nutr. 2003;27(5):355–373.
25. Cook D, Guyatt G, Marshall J, et al. A comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group. N.Engl.J.Med. 1998;338(12):791–797.
26. Bell CM, Fischer HD, Gill SS, et al. Initiation of benzodiazepines in the elderly after hospitalization. J Gen Intern Med. 2007;22(7):1024–1029.
27. Jackevicius CA, Mamdani M, Tu JV. Adherence with statin therapy in elderly patients with and without acute coronary syndromes. JAMA. 2002;288(4):462–467.
28. Alam A, Gomes T, Zheng H, Mandani M. Long-term analgesic use after low-risk surgery. Arch Intern Med. 2012;172:425–430.
29. Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45(6):613–9.
30. Schneeweiss S, Maclure M, Soumerai SB, Walker AM, Glynn RJ. Quasi-experimental longitudinal designs to evaluate drug benefit policy changes with low policy compliance. J Clin Epidemiol. 2002;55(8):833–841.
31. Schneeweiss S, Seeger JD, Maclure M, Wang PS, Avorn J, Glynn RJ. Performance of comorbidity scores to control for confounding in epidemiologic studies using claims data. Am J Epidemiol. 2001;154(9):854–864.
32. Jasiak KD, Middleton EA, Camamo JM, Erstad BL, Snyder LS, Huckleberry YC. Evaluation of discontinuation of atypical antipsychotics prescribed for ICU delirium. J Pharm Pract. 2013;26(3):253–256.
33. Wohlt PD, Hansen LA, Fish JT. Inappropriate continuation of stress ulcer prophylactic therapy after discharge. Ann Pharmacother. 2007;41(10):1611–1616.
34. Ong SW, Fernandes OA, Cesta A, Bajcar JM. Drug-related problems on hospital admission: relationship to medication information transfer. Ann Pharmacother. 2006;40(3):408–413.
35. Bajcar JM, Kennie N, Einarson TR. Collaborative medication management in a team-based primary care practice: an explanatory conceptual framework. Res Social Adm Pharm. 2005;1(3):408–429.
36. Cassel CK, Guest JA. Choosing wisely: helping physicians and patients make smart decisions about their care. JAMA: J Am Med Assoc. 2012;307(17):1801–1802.
37. Brody H. Medicine’s ethical responsibility for health care reform--the Top Five list. N Engl J Med. 2010;362(4):283–285.