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Volumn 1995, Issue 10, 1995, Pages 1017-1020

Solid Phase Synthesis of Bicyclo[22.2]octane Derivatives via Tandem Michael Addition Reactions and Subsequent Reductive Amination

Author keywords

Reductive Amination; Solid Phase Synthesis; Tandem Michael Addition

Indexed keywords


EID: 84955066834     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-1995-5164     Document Type: Article
Times cited : (89)

References (47)
  • 39
    • 85066068055 scopus 로고    scopus 로고
    • The resin used was purchased from Sigma (p-Alkoxybenzyl Alcohol Resin 0. 69 mmol per g resin, Cat. # A3039) 9. 3'-Th = 3'-Thiophene adduct, 2'-Th = 2'-Thiophene adduct and 3'Fu = 3'-furan adduct
    • The resin used was purchased from Sigma (p-Alkoxybenzyl Alcohol Resin 0. 69 mmol per g resin, Cat. # A3039) 9. 3'-Th = 3'-Thiophene adduct, 2'-Th = 2'-Thiophene adduct and 3'Fu = 3'-furan adduct.
  • 40
    • 85066088130 scopus 로고    scopus 로고
    • All reactions were monitored by ir and gel-phase 13c nmr. Gel-phase 13c nmr spectra were obtained in cd2ci2
    • All reactions were monitored by IR and gel-phase 13C NMR. Gel-phase 13c NMR spectra were obtained in CD2CI2.
  • 43
    • 85066075036 scopus 로고    scopus 로고
    • So far, we have made no attempts to optimise this reaction, although we are aware of the fact that this yield is hardly applicable for solid phase synthesis
    • So far, we have made no attempts to optimise this reaction, although we are aware of the fact that this yield is hardly applicable for solid phase synthesis.
  • 44
    • 85066091466 scopus 로고    scopus 로고
    • Attemps to influence the endo/exo ratio in the preparation of compounds 22 and 23 in solution using excess enolate in the condensation reaction failed
    • Attemps to influence the endo/exo ratio in the preparation of compounds 22 and 23 in solution using excess enolate in the condensation reaction failed.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.