Discordance between Iothalamate and Iohexol Urinary Clearances

American Journal of Kidney Diseases

Volumn 67, Issue 1, 2016, Pages 49-55

  Seegmiller, Jesse C ^a   Burns, Bradley E ^b   Schinstock, Carrie A ^b   Lieske, John C ^b   Larson, Timothy S ^b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

exogenous filtration marker; Glomerular filtration rate (GFR); iohexol; iothalamate; kidney function; liquid chromatography tandem mass spectrometry (LC MS MS); measured GFR (mGFR); plasma; renal clearance; urine

Indexed keywords

CREATININE; IOHEXOL; MEGLUMINE IOTALAMATE; IOTALAMIC ACID;

ADULT; AGE; AGED; ARTICLE; BONE MARROW TRANSPLANTATION; CHRONIC KIDNEY DISEASE; CLINICAL EVALUATION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CREATININE CLEARANCE; DRUG BLOOD LEVEL; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; MEASUREMENT ACCURACY; ORGAN TRANSPLANTATION; PROTEIN BINDING; RENAL CLEARANCE; STAGING; TANDEM MASS SPECTROMETRY; BLOOD EXAMINATION; KIDNEY FUNCTION TEST; MIDDLE AGED; PROSPECTIVE STUDY; REPRODUCIBILITY; URINALYSIS; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; CHROMATOGRAPHY, LIQUID; FEMALE; GLOMERULAR FILTRATION RATE; HEMATOLOGIC TESTS; HUMANS; IOHEXOL; IOTHALAMIC ACID; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; URINALYSIS; YOUNG ADULT;

EID: 84954451086     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2015.08.020     Document Type: Article

References (20)

1. E.M. Sigman, C.M. Elwood, and F. Knox The measurement of glomerular filtration rate in man with sodium iothalamate 131-I (Conray) J Nucl Med 7 1965 60 68
2. 125I-sodium iothalamate (Conray) Br J Radiol 40 1967 581 583
3. F.T. Maher, N.G. Nolan, and L.R. Elveback Comparison of simultaneous clearances of 125-I-labeled sodium iothalamate (Glofil) and of inulin Mayo Clin Proc 46 1971 690 691
4. J. Milutinovic, R.E. Cutler, P. Hoover, B. Meijsen, and B.H. Scribner Measurement of residual glomerular filtration rate in the patient receiving repetitive hemodialysis Kidney Int 8 1975 185 190
5. Y. Isaka, S. Yamamoto, Y. Fujiwara, and et al. [A new analytical method for simultaneous measurement of iothalamate and iohexol] Rinsho Byori 40 1992 703 707
6. F.T. Maher, and W.N. Tauxe Renal clearance in man of pharmaceuticals containing radioactive iodine JAMA 207 1969 97 104
7. S.C. Brown, and P.H. O'Reilly Iohexol clearance for the determination of glomerular filtration rate in clinical practice: evidence for a new gold standard J Urol 146 1991 675 679
8. S.E. Back, E. Krutzen, and P. Nilsson-Ehle Contrast media as markers for glomerular filtration: a pharmacokinetic comparison of four agents Scand J Clin Lab Invest 48 1988 247 253
9. S.E. Back, E. Krutzen, and P. Nilsson-Ehle Contrast media and glomerular filtration: dose dependence of clearance for three agents J Pharm Sci 77 1988 765 767
10. 125I iothalamate an ideal marker for glomerular filtration? Kidney Int 27 1985 9 16
11. C. Zurth Mechanism of renal excretion of various x-ray contrast materials in rabbits Invest Radiol 19 1984 110 115
12. R. Masereeuw, M.M. Moons, P. Smits, and F.G. Russel Glomerular filtration and saturable absorption of iohexol in the rat isolated perfused kidney Br J Pharmacol 119 1996 57 64
13. B. Olsson, A. Aulie, K. Sveen, and E. Andrew Human pharmacokinetics of iohexol. A new nonionic contrast medium Invest Radiol 18 1983 177 182
14. D.M. Wilson, J.H. Bergert, T.S. Larson, and R.R. Liedtke GFR determined by nonradiolabeled iothalamate using capillary electrophoresis Am J Kidney Dis 30 1997 646 652
15. J.C. Seegmiller, B.E. Burns, A.H. Fauq, N. Mukhtar, J.C. Lieske, and T.S. Larson Iothalamate quantification by tandem mass spectrometry to measure glomerular filtration rate Clin Chem 56 2010 568 574
16. I. Soveri, U.B. Berg, J. Bjork, and et al. Measuring GFR: a systematic review Am J Kidney Dis 64 2014 411 424
17. E. Krutzen, S.E. Back, I. Nilsson-Ehle, and P. Nilsson-Ehle Plasma clearance of a new contrast agent, iohexol: a method for the assessment of glomerular filtration rate J Lab Clin Med 104 1984 955 961
18. K.W. Florijn, J.N. Barendregt, E.G. Lentjes, and et al. Glomerular filtration rate measurement by "single-shot" injection of inulin Kidney Int 46 1994 252 259
19. 51Cr-labelled ethylenediaminetetra-acetate and inulin in man Clin Sci (Lond) 66 1984 613 619
20. L.A. Inker, C.A. Schmid, H. Tighiouart, and et al. Estimating glomerular filtration rate from serum creatinine and cystatin C N Engl J Med 367 2012 20 29