A prospective study of leisure-time physical activity and risk of incident epithelial ovarian cancer: Impact by menopausal status

International Journal of Cancer

Volumn 138, Issue 4, 2016, Pages 843-852

  Huang, Tianyi ^a,b   Eliassen, A Heather ^a,b   Hankinson, Susan E ^a,b,c   Okereke, Olivia I ^a,b   Kubzansky, Laura D ^b   Wang, Molin ^a,b   Poole, Elizabeth M ^a   Chavarro, Jorge E ^a,b   Tworoger, Shelley S ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

luteal progesterone; menopausal status; ovarian cancer; ovulation; physical activity

Indexed keywords

CAFFEINE; LACTOSE; ORAL CONTRACEPTIVE AGENT; PROGESTERONE;

ADULT; AGED; ARTICLE; BODY MASS; CANCER INCIDENCE; CANCER RISK; CASE CONTROL STUDY; CLINICAL STUDY; COHORT ANALYSIS; CONTROLLED STUDY; DEATH; EXERCISE INTENSITY; FEMALE; FOLLOW UP; HAZARD RATIO; HIGH RISK PATIENT; HUMAN; HUMAN TISSUE; LEISURE; MAJOR CLINICAL STUDY; METABOLIC EQUIVALENT; OBESITY; OVARY CARCINOMA; OVULATION; PHYSICAL ACTIVITY; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; QUESTIONNAIRE; UNDERWEIGHT; UNITED STATES; VALIDATION STUDY; WALKING; INCIDENCE; MIDDLE AGED; MOTOR ACTIVITY; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PHYSIOLOGY; RISK FACTOR;

ADULT; FEMALE; HUMANS; INCIDENCE; MIDDLE AGED; MOTOR ACTIVITY; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; POSTMENOPAUSE; PREMENOPAUSE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84954363227     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29834     Document Type: Article

References (43)

1. Warburton DE, Nicol CW, Bredin SS., Health benefits of physical activity: the evidence. CMAJ 2006; 174: 801-9.
2. McTiernan A., Mechanisms linking physical activity with cancer. Nat Rev Cancer 2008; 8: 205-11.
3. Siegel R, Naishadham D, Jemal A., Cancer statistics, 2013. CA Cancer J Clin 2013; 63: 11-30.
4. Cannioto RA, Moysich KB., Epithelial ovarian cancer and recreational physical activity: a review of the epidemiological literature and implications for exercise prescription. Gynecol Oncol 2015; 137: 559-73.
5. Zhong S, Chen L, Lv M, et al.,. Nonoccupational physical activity and risk of ovarian cancer: a meta-analysis. Tumour Biol 2014; 35: 11065-73.
6. Weiderpass E, Margolis KL, Sandin S, et al., Prospective study of physical activity in different periods of life and the risk of ovarian cancer. Int J Cancer 2006; 118: 3153-60.
7. Weiderpass E, Sandin S, Inoue M, et al., Risk factors for epithelial ovarian cancer in Japan-results from the Japan Public Health Center-based Prospective Study cohort. Int J Oncol 2012; 40: 21-30.
8. Patel AV, Rodriguez C, Pavluck AL, et al., Recreational physical activity and sedentary behavior in relation to ovarian cancer risk in a large cohort of US women. Am J Epidemiol 2006; 163: 709-16.
9. Xiao Q, Yang HP, Wentzensen N, et al., Physical activity in different periods of life, sedentary behavior, and the risk of ovarian cancer in the NIH-AARP Diet and Health Study. Cancer Epidemiol Biomarkers Prev 2013; 22: 2000-8.
10. Lahmann PH, Friedenreich C, Schulz M, et al., Physical activity and ovarian cancer risk: the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev 2009; 18: 351-4.
11. Leitzmann MF, Koebnick C, Moore SC, et al., Prospective study of physical activity and the risk of ovarian cancer. Cancer Causes Control 2009; 20: 765-73.
12. Hannan LM, Leitzmann MF, Lacey JV, et al., Physical activity and risk of ovarian cancer: a prospective cohort study in the United States. Cancer Epidemiol Biomarkers Prev 2004; 13: 765-70.
13. Bertone ER, Willett WC, Rosner BA, et al., Prospective study of recreational physical activity and ovarian cancer. J Natl Cancer Inst 2001; 93: 942-8.
14. Anderson JP, Ross JA, Folsom AR., Anthropometric variables, physical activity, and incidence of ovarian cancer: the Iowa Women's Health Study. Cancer 2004; 100: 1515-21.
15. Chionh F, Baglietto L, Krishnan K, et al., Physical activity, body size and composition, and risk of ovarian cancer. Cancer Causes Control 2010; 21: 2183-94.
16. Tung KH, Wilkens LR, Wu AH, et al., Effect of anovulation factors on pre- and postmenopausal ovarian cancer risk: revisiting the incessant ovulation hypothesis. Am J Epidemiol 2005; 161: 321-9.
17. Rich-Edwards JW, Spiegelman D, Garland M, et al., Physical activity, body mass index, and ovulatory disorder infertility. Epidemiology 2002; 13: 184-90.
18. Tworoger SS, Missmer SA, Eliassen AH, et al., Physical activity and inactivity in relation to sex hormone, prolactin, and insulin-like growth factor concentrations in premenopausal women-exercise and premenopausal hormones. Cancer Causes Control 2007; 18: 743-52.
19. De Souza MJ, Miller BE, Loucks AB, et al., High frequency of luteal phase deficiency and anovulation in recreational women runners: blunted elevation in follicle-stimulating hormone observed during luteal-follicular transition. J Clin Endocrinol Metab 1998; 83: 4220-32.
20. De Souza MJ, Van Heest J, Demers LM, et al., Luteal phase deficiency in recreational runners: evidence for a hypometabolic state. J Clin Endocrinol Metab 2003; 88: 337-46.
21. Ahrens KA, Vladutiu CJ, Mumford SL, et al., The effect of physical activity across the menstrual cycle on reproductive function. Ann Epidemiol 2014; 24: 127-34.
22. Lukanova A, Kaaks R., Endogenous hormones and ovarian cancer: epidemiology and current hypotheses. Cancer Epidemiol Biomarkers Prev 2005; 14: 98-107.
23. Wathen NC, Perry L, Lilford RJ, et al., Interpretation of single progesterone measurement in diagnosis of anovulation and defective luteal phase: observations on analysis of the normal range. Br Med J (Clin Res Ed) 1984; 288: 7-9.
24. Ainsworth BE, Haskell WL, Leon AS, et al., Compendium of physical activities: classification of energy costs of human physical activities. Med Sci Sports Exerc 1993; 25: 71-80.
25. Wolf AM, Hunter DJ, Colditz GA, et al., Reproducibility and validity of a self-administered physical activity questionnaire. Int J Epidemiol 1994; 23: 991-9.
26. Tworoger SS, Hecht JL, Giovannucci E, et al., Intake of folate and related nutrients in relation to risk of epithelial ovarian cancer. Am J Epidemiol 2006; 163: 1101-11.
27. Lunn M, McNeil D., Applying Cox regression to competing risks. Biometrics 1995; 51: 524-32.
28. Rosner B, Cook N, Portman R, et al., Determination of blood pressure percentiles in normal-weight children: some methodological issues. Am J Epidemiol 2008; 167: 653-66.
29. Carlberg K, Buckman M, Peake G, et al., A survey of menstrual function in athletes. Eur J Appl Physiol Occup Physiol 1983; 51: 211-22.
30. Bullen BA, Skrinar GS, Beitins IZ, et al., Induction of menstrual disorders by strenuous exercise in untrained women. N Engl J Med 1985; 312: 1349-53.
31. Russell JB, Mitchell D, Musey PI, et al., The relationship of exercise to anovulatory cycles in female athletes: hormonal and physical characteristics. Obstet Gynecol 1984; 63: 452-6.
32. Shangold M, Freeman R, Thysen B, et al., The relationship between long-distance running, plasma progesterone, and luteal phase length. Fertil Steril 1979; 31: 130-3.
33. Frisch RE, Gotz-Welbergen AV, McArthur JW, et al., Delayed menarche and amenorrhea of college athletes in relation to age of onset of training. JAMA 1981; 246: 1559-63.
34. Williams NI, Helmreich DL, Parfitt DB, et al., Evidence for a causal role of low energy availability in the induction of menstrual cycle disturbances during strenuous exercise training. J Clin Endocrinol Metab 2001; 86: 5184-93.
35. Loucks AB., Energy availability, not body fatness, regulates reproductive function in women. Exerc Sport Sci Rev 2003; 31: 144-8.
36. Williams NI, Caston-Balderrama AL, Helmreich DL, et al.,. Longitudinal changes in reproductive hormones and menstrual cyclicity in cynomolgus monkeys during strenuous exercise training: abrupt transition to exercise-induced amenorrhea. Endocrinology 2001; 142: 2381-9.
37. Bonen A., Recreational exercise does not impair menstrual cycles: a prospective study. Int J Sports Med 1992; 13: 110-20.
38. Rogol AD, Weltman A, Weltman JY, et al., Durability of the reproductive axis in eumenorrheic women during 1 yr of endurance training. J Appl Physiol (1985) 1992; 72: 1571-80.
39. Missmer SA, Spiegelman D, Bertone-Johnson ER, et al., Reproducibility of plasma steroid hormones, prolactin, and insulin-like growth factor levels among premenopausal women over a 2- to 3-year period. Cancer Epidemiol Biomarkers Prev 2006; 15: 972-8.
40. Riman T, Nilsson S, Persson IR., Review of epidemiological evidence for reproductive and hormonal factors in relation to the risk of epithelial ovarian malignancies. Acta Obstet Gynecol Scand 2004; 83: 783-95.
41. Schmid D, Behrens G, Keimling M, et al., A systematic review and meta-analysis of physical activity and endometrial cancer risk. Eur J Epidemiol 2015; 30: 397-412.
42. Poole EM, Lee IM, Ridker PM, et al.,. A prospective study of circulating C-reactive protein, interleukin-6, and tumor necrosis factor alpha receptor 2 levels and risk of ovarian cancer. Am J Epidemiol 2013; 178: 1256-64.
43. Clendenen TV, Lundin E, Zeleniuch-Jacquotte A, et al., Circulating inflammation markers and risk of epithelial ovarian cancer. Cancer Epidemiol Biomarkers Prev 2011; 20: 799-810.