Evaluation of brain targeting efficiency of intranasal microemulsion containing olanzapine: Pharmacodynamic and pharmacokinetic consideration

Drug Delivery

Volumn 23, Issue 1, 2016, Pages 307-315

  Patel, Rashmin B ^a   Patel, Mrunali R ^b   Bhatt, Kashyap K ^b   Patel, Bharat G ^c   Gaikwad, Rajiv V ^d  

^a AR Patel and GH Patel Institute of Pharmacy   (India)

^b Indukaka Ipcowala College of Pharmacy   (India)

^c CHAROTAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

^d BOMBAY VETERINARY COLLEGE   (India)

Author keywords

Brain scintigraphy; microemulsion; olanzapine; pharmacodynamic study; pharmacokinetic study

Indexed keywords

CARBIDOPA; DISTILLED WATER; HALOPERIDOL; LEVODOPA; OLANZAPINE; OLANZAPINE TC 99; TRACER; UNCLASSIFIED DRUG; APOMORPHINE; BENZODIAZEPINE DERIVATIVE; EMULSION; NEUROLEPTIC AGENT; TECHNETIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN SCINTISCANNING; COMPULSION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG STABILITY; DRUG TARGETING; DRUG TRANSPORT; FEMALE; IN VIVO STUDY; LOCOMOTION; MALE; MICROEMULSION; MOUSE; MUCOADHESIVE MICROEMULSION; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; STEREOTYPY; ANIMAL; CHEMICALLY INDUCED; COMPULSIVE BEHAVIOR; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEM; DRUG EFFECTS; EMULSION; INTRANASAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; MOTOR ACTIVITY; PSYCHOLOGY; SCINTISCANNING; TISSUE DISTRIBUTION; WISTAR RAT;

ADMINISTRATION, INTRANASAL; ADMINISTRATION, INTRAVENOUS; ANIMALS; ANTIPSYCHOTIC AGENTS; APOMORPHINE; BENZODIAZEPINES; BRAIN; CHEMISTRY, PHARMACEUTICAL; COMPULSIVE BEHAVIOR; DRUG DELIVERY SYSTEMS; EMULSIONS; MALE; MICE; MOTOR ACTIVITY; RABBITS; RADIONUCLIDE IMAGING; RATS; RATS, WISTAR; TECHNETIUM; TISSUE DISTRIBUTION;

EID: 84954307062     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2014.912694     Document Type: Article

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