No added value of interferon-ã release to a prediction model for childhood tuberculosis

European Respiratory Journal

Volumn 47, Issue 1, 2016, Pages 223-232

  Togun, Toyin O ^a   Egere, Uzochukwu ^a   Gomez, Marie P ^a   Sillah, Abdou K ^a   Daramy, Mohammed ^a   Tientcheu, Leopold D ^a   Sutherland, Jayne S ^a   Hill, Philip C ^b   Kampmann, Beate ^a,c  

^a MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; GAMMA INTERFERON; TUBERCULOSTATIC AGENT;

ADOLESCENT; AGE; ARTICLE; CHILD; CLINICAL FEATURE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE CLASSIFICATION; EXPOSURE; FEMALE; HUMAN; INFANT; LYMPHADENOPATHY; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; ONSET AGE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPIRATORY TRACT INFECTION; STATISTICAL MODEL; TREATMENT DURATION; TREATMENT RESPONSE; TUBERCULIN TEST; TUBERCULOSIS; ALGORITHM; AREA UNDER THE CURVE; COMPLICATION; CONTACT EXAMINATION; COUGH; DECISION SUPPORT SYSTEM; FEVER; INTERFERON GAMMA RELEASE ASSAY; PRESCHOOL CHILD; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; TUBERCULOSIS, PULMONARY; WEIGHT REDUCTION;

ADOLESCENT; AGE FACTORS; ALGORITHMS; AREA UNDER CURVE; CHILD; CHILD, PRESCHOOL; CONTACT TRACING; COUGH; DECISION SUPPORT TECHNIQUES; FEMALE; FEVER; HUMANS; INFANT; INTERFERON-GAMMA RELEASE TESTS; LOGISTIC MODELS; LYMPHADENOPATHY; MALE; PROSPECTIVE STUDIES; RISK ASSESSMENT; ROC CURVE; TUBERCULOSIS; TUBERCULOSIS, PULMONARY; WEIGHT LOSS;

EID: 84954306311     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/13993003.00890-2015     Document Type: Article

References (30)

1. Graham SM, Sismanidis C, Menzies HJ, et al. Importance of tuberculosis control to address child survival. Lancet 2014; 383: 1605-1607.
2. Nelson LJ, Wells CD. Global epidemiology of childhood tuberculosis. Int J Tuberc Lung Dis 2004; 8: 636-647.
3. Guwatudde D, Nakakeeto M, Jones-Lopez EC, et al. Tuberculosis in household contacts of infectious cases in Kampala, Uganda. Am J Epidemiol 2003; 158: 887-898.
4. Marais BJ, Gie RP, Schaaf HS, et al. The clinical epidemiology of childhood pulmonary tuberculosis: A critical review of literature from the pre-chemotherapy era. Int J Tuberc Lung Dis 2004; 8: 278-285.
5. Perez-Velez CM, Marais BJ. Tuberculosis in children. N Engl J Med 2012; 367: 348-361.
6. Newton SM, Brent AJ, Anderson S, et al. Paediatric tuberculosis. Lancet Infect Dis 2008; 8: 498-510.
7. Marais BJ, Gie RP, Hesseling AC, et al. A refined symptom-based approach to diagnose pulmonary tuberculosis in children. Pediatrics 2006; 118: E1350-e1359.
8. Pai M, Zwerling A, Menzies D. Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: An update. Ann Intern Med 2008; 149: 177-184.
9. Rangaka MX, Wilkinson KA, Glynn JR, et al. Predictive value of interferon- release assays for incident active tuberculosis: A systematic review and meta-analysis. Lancet Infect Dis 2012; 12: 45-55.
10. Pollock L, Basu Roy R, Kampmann B. How to use: Interferon release assays for tuberculosis. Arch Dis Child Educ Pract Ed 2013; 98: 99-105.
11. Moons KG, Grobbee DE. Diagnostic studies as multivariable, prediction research. J Epidemiol Community Health 2002; 56: 337-338.
12. Moons KG, van Es GA, Michel BC, et al. Redundancy of single diagnostic test evaluation. Epidemiology 1999; 10: 276-281.
13. Adetifa IM, Ota MO, Jeffries DJ, et al. Commercial interferon gamma release assays compared to the tuberculin skin test for diagnosis of latent Mycobacterium tuberculosis infection in childhood contacts in the Gambia. Pediatr Infect Dis J 2010; 29: 439-443.
14. Hill PC, Brookes RH, Adetifa IM, et al. Comparison of enzyme-linked immunospot assay and tuberculin skin test in healthy children exposed to Mycobacterium tuberculosis. Pediatrics 2006; 117: 1542-1548.
15. World Health Organization. Global Tuberculosis Report 2014. http://apps.who.int/iris/bitstream/10665/137094/1/9789241564809-eng.pdfua=1 Date last accessed: March 1, 2015.
16. UNAIDS. Global Report: UNAIDS Report on the Global AIDS Epidemic 2013. www.unaids.org/sites/default/files/media-asset/UNAIDS-Global-Report-2013-en-1.pdf Date last accessed: December 4, 2014.
17. World Health Organization. WHO Child Growth Standards: Methods and Development. Length/Height for Age, Weight for Age, Weight for Length, Weight for Height and Body Mass Index for Age. Geneva, World Health Organization, 2007.
18. World Health Organization. Definitions and Reporting Framework for Tuberculosis-2013 Revision. www.who. int/iris/bitstream/10665/79199/1/9789241505345-eng.pdf Date last accessed: December 3, 2014. Date last updated: December 2014.
19. Gambian National Leprosy and Tuberculosis Control Programme. Gambian National Leprosy and Tuberculosis Control Programme: National Guidelines for the Management of Tuberculosis. Banjul, Department of State for Health, The Gambia, 2012.
20. Black GF, Thiel BA, Ota MO, et al. Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa. Clin Vaccine Immunol 2009; 16: 1203-1212.
21. Sutherland JS, Lalor MK, Black GF, et al. Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. PLoS One 2013; 8: E74080.
22. Kassa D, Ran L, Geberemeskel W, et al. Analysis of immune responses against a wide range of Mycobacterium tuberculosis antigens in patients with active pulmonary tuberculosis. Clin Vaccine Immunol 2012; 19: 1907-1915.
23. Schaaf HS, Beyers N, Gie RP, et al. Respiratory tuberculosis in childhood: The diagnostic value of clinical features and special investigations. Pediatr Infect Dis J 1995; 14: 189-194.
24. Marais BJ, Gie RP, Obihara CC, et al. Well defined symptoms are of value in the diagnosis of childhood pulmonary tuberculosis. Arch Dis Child 2005; 90: 1162-1165.
25. Moons KG, Kengne AP, Woodward M, et al. Risk prediction models: I. Development, internal validation, and assessing the incremental value of a new (bio)marker. Heart 2012; 98: 683-690.
26. Marais BJ, Obihara CC, Gie RP, et al. The prevalence of symptoms associated with pulmonary tuberculosis in randomly selected children from a high burden community. Arch Dis Child 2005; 90: 1166-1170.
27. Lewinsohn DA, Zalwango S, Stein CM, et al. Whole blood interferon-gamma responses to Mycobacterium tuberculosis antigens in young household contacts of persons with tuberculosis in Uganda. PLoS One 2008; 3: E3407.
28. Critselis E, Amanatidou V, Syridou G, et al. The effect of age on whole blood interferon-gamma release assay response among children investigated for latent tuberculosis infection. J Pediatr 2012; 161: 632-638.
29. Machingaidze S, Wiysonge CS, Gonzalez-Angulo Y, et al. The utility of an interferon gamma release assay for diagnosis of latent tuberculosis infection and disease in children: A systematic review and meta-analysis. Pediatr Infect Dis J 2011; 30: 694-700.
30. Graham SM, Ahmed T, Amanullah F, et al. Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel. J Infect Dis 2012; 205: Suppl. 2, S199-S208.