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Volumn 173, Issue 1, 2016, Pages 60-68

Dysregulated ErbB4 splicing in schizophrenia: Selective effects on parvalbumin expression

Author keywords

[No Author keywords available]

Indexed keywords

CALRETININ; EPIDERMAL GROWTH FACTOR RECEPTOR 4; MESSENGER RNA; MYOCARDIAL INFARCTION ASSOCIATED TRANSCRIPT; PARVALBUMIN; UNCLASSIFIED DRUG; UNTRANSLATED RNA; ERBB4 PROTEIN, HUMAN;

EID: 84954305428     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2015.15020150     Document Type: Article
Times cited : (71)

References (40)
  • 1
    • 79957590910 scopus 로고    scopus 로고
    • Neuregulin signaling, cortical circuitry development and schizophrenia
    • Rico B, Marín O: Neuregulin signaling, cortical circuitry development and schizophrenia. Curr Opin Genet Dev 2011;21:262-270
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 262-270
    • Rico, B.1    Marín, O.2
  • 2
    • 84903650231 scopus 로고    scopus 로고
    • Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases
    • Mei L, Nave KA: Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases. Neuron 2014;83:27-49
    • (2014) Neuron , vol.83 , pp. 27-49
    • Mei, L.1    Nave, K.A.2
  • 4
    • 33846589304 scopus 로고    scopus 로고
    • Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia
    • Law AJ, Kleinman JE, Weinberger DR, et al: Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia. Hum Mol Genet 2007;16:129-141
    • (2007) Hum Mol Genet , vol.16 , pp. 129-141
    • Law, A.J.1    Kleinman, J.E.2    Weinberger, D.R.3
  • 5
    • 84897422927 scopus 로고    scopus 로고
    • Elevated ErbB4 mRNA is related to interneuron deficit in prefrontal cortex in schizophrenia
    • Joshi D, Fullerton JM, Weickert CS: Elevated ErbB4 mRNA is related to interneuron deficit in prefrontal cortex in schizophrenia. J Psychiatr Res 2014;53:125-132
    • (2014) J Psychiatr Res , vol.53 , pp. 125-132
    • Joshi, D.1    Fullerton, J.M.2    Weickert, C.S.3
  • 6
    • 84864340439 scopus 로고    scopus 로고
    • Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110d inhibition as a potential therapeutic strategy
    • Law AJ, Wang Y, Sei Y, et al: Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110d inhibition as a potential therapeutic strategy. Proc Natl Acad Sci USA 2012;109:12165-12170
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 12165-12170
    • Law, A.J.1    Wang, Y.2    Sei, Y.3
  • 7
    • 84897108067 scopus 로고    scopus 로고
    • The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing
    • Barry G, Briggs JA, Vanichkina DP, et al: The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing. Mol Psychiatry 2014;19:486-494
    • (2014) Mol Psychiatry , vol.19 , pp. 486-494
    • Barry, G.1    Briggs, J.A.2    Vanichkina, D.P.3
  • 8
    • 80051764374 scopus 로고    scopus 로고
    • Function of ERBB4 is determined by alternative splicing
    • Veikkolainen V, Vaparanta K, Halkilahti K, et al: Function of ERBB4 is determined by alternative splicing. Cell Cycle 2011;10:2647-2657
    • (2011) Cell Cycle , vol.10 , pp. 2647-2657
    • Veikkolainen, V.1    Vaparanta, K.2    Halkilahti, K.3
  • 9
    • 77958550106 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the human ErbB4 gene: Identification of novel splice isoforms in the developing and adult brain
    • Tan W, Dean M, Law AJ: Molecular cloning and characterization of the human ErbB4 gene: identification of novel splice isoforms in the developing and adult brain. PLoS ONE 2010;5:e12924
    • (2010) PLoS ONE , vol.5 , pp. e12924
    • Tan, W.1    Dean, M.2    Law, A.J.3
  • 10
    • 0034616385 scopus 로고    scopus 로고
    • Tumor necrosis factor-alphaconverting enzyme is required for cleavage of erbB4/HER4
    • Rio C, Buxbaum JD, Peschon JJ, et al: Tumor necrosis factor-alphaconverting enzyme is required for cleavage of erbB4/HER4. J Biol Chem 2000;275:10379-10387
    • (2000) J Biol Chem , vol.275 , pp. 10379-10387
    • Rio, C.1    Buxbaum, J.D.2    Peschon, J.J.3
  • 11
    • 0037155219 scopus 로고    scopus 로고
    • Presenilin-dependent gammasecretaselike intramembrane cleavage of ErbB4
    • Lee HJ, Jung KM, Huang YZ, et al: Presenilin-dependent gammasecretaselike intramembrane cleavage of ErbB4. J Biol Chem 2002;277:6318-6323
    • (2002) J Biol Chem , vol.277 , pp. 6318-6323
    • Lee, H.J.1    Jung, K.M.2    Huang, Y.Z.3
  • 12
    • 0035824391 scopus 로고    scopus 로고
    • G-Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
    • Ni CY, Murphy MP, Golde TE, et al: g-Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science 2001;294:2179-2181
    • (2001) Science , vol.294 , pp. 2179-2181
    • Ni, C.Y.1    Murphy, M.P.2    Golde, T.E.3
  • 13
    • 0034351216 scopus 로고    scopus 로고
    • Erbb4 and its isoforms: Selective regulation of growth factor responses by naturally occurring receptor variants
    • Junttila TT, Sundvall M, Määttä JA, et al: Erbb4 and its isoforms: selective regulation of growth factor responses by naturally occurring receptor variants. Trends Cardiovasc Med 2000;10:304-310
    • (2000) Trends Cardiovasc Med , vol.10 , pp. 304-310
    • Junttila, T.T.1    Sundvall, M.2    Määttä, J.A.3
  • 14
    • 77951879644 scopus 로고    scopus 로고
    • Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling
    • Fazzari P, Paternain AV, Valiente M, et al: Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling. Nature 2010;464:1376-1380
    • (2010) Nature , vol.464 , pp. 1376-1380
    • Fazzari, P.1    Paternain, A.V.2    Valiente, M.3
  • 15
    • 84884266306 scopus 로고    scopus 로고
    • Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes
    • Del Pino I, García-Frigola C, Dehorter N, et al: Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes. Neuron 2013;79:1152-1168
    • (2013) Neuron , vol.79 , pp. 1152-1168
    • Del Pino, I.1    García-Frigola, C.2    Dehorter, N.3
  • 16
    • 78650860729 scopus 로고    scopus 로고
    • Neuregulin 1 promotes excitatory synapse development and function in GABAergic interneurons
    • Ting AK, Chen Y, Wen L, et al: Neuregulin 1 promotes excitatory synapse development and function in GABAergic interneurons. J Neurosci 2011;31:15-25
    • (2011) J Neurosci , vol.31 , pp. 15-25
    • Ting, A.K.1    Chen, Y.2    Wen, L.3
  • 17
    • 73949136265 scopus 로고    scopus 로고
    • Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes
    • Belforte JE, Zsiros V, Sklar ER, et al: Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nat Neurosci 2010;13:76-83
    • (2010) Nat Neurosci , vol.13 , pp. 76-83
    • Belforte, J.E.1    Zsiros, V.2    Sklar, E.R.3
  • 18
    • 84862898614 scopus 로고    scopus 로고
    • Activity-dependent regulation of inhibition via GAD67
    • Lau CG, Murthy VN: Activity-dependent regulation of inhibition via GAD67. J Neurosci 2012;32:8521-8531
    • (2012) J Neurosci , vol.32 , pp. 8521-8531
    • Lau, C.G.1    Murthy, V.N.2
  • 19
    • 32544436072 scopus 로고    scopus 로고
    • A specific role for NR2AcontainingNMDAreceptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons
    • Kinney JW, Davis CN, Tabarean I, et al: A specific role for NR2AcontainingNMDAreceptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons. J Neurosci 2006;26:1604-1615
    • (2006) J Neurosci , vol.26 , pp. 1604-1615
    • Kinney, J.W.1    Davis, C.N.2    Tabarean, I.3
  • 20
    • 0037705995 scopus 로고    scopus 로고
    • Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia
    • Hashimoto T, Volk DW, Eggan SM, et al: Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia. J Neurosci 2003;23:6315-6326
    • (2003) J Neurosci , vol.23 , pp. 6315-6326
    • Hashimoto, T.1    Volk, D.W.2    Eggan, S.M.3
  • 21
    • 67349117808 scopus 로고    scopus 로고
    • Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia
    • Mellios N, Huang HS, Baker SP, et al: Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia. Biol Psychiatry 2009;65:1006-1014
    • (2009) Biol Psychiatry , vol.65 , pp. 1006-1014
    • Mellios, N.1    Huang, H.S.2    Baker, S.P.3
  • 22
    • 77955277280 scopus 로고    scopus 로고
    • Expression of interneuron markers in the dorsolateral prefrontal cortex of the developing human and in schizophrenia
    • Fung SJ, Webster MJ, Sivagnanasundaram S, et al: Expression of interneuron markers in the dorsolateral prefrontal cortex of the developing human and in schizophrenia. Am J Psychiatry 2010;167:1479-1488
    • (2010) Am J Psychiatry , vol.167 , pp. 1479-1488
    • Fung, S.J.1    Webster, M.J.2    Sivagnanasundaram, S.3
  • 23
    • 84865307957 scopus 로고    scopus 로고
    • Deficits in transcriptional regulators of cortical parvalbumin neurons in schizophrenia
    • Volk DW, Matsubara T, Li S, et al: Deficits in transcriptional regulators of cortical parvalbumin neurons in schizophrenia. Am J Psychiatry 2012;169:1082-1091
    • (2012) Am J Psychiatry , vol.169 , pp. 1082-1091
    • Volk, D.W.1    Matsubara, T.2    Li, S.3
  • 24
    • 84891157330 scopus 로고    scopus 로고
    • Altered parvalbumin basket cell inputs in the dorsolateral prefrontal cortex of schizophrenia subjects
    • Glausier JR, Fish KN, Lewis DA: Altered parvalbumin basket cell inputs in the dorsolateral prefrontal cortex of schizophrenia subjects. Mol Psychiatry 2014;19:30-36
    • (2014) Mol Psychiatry , vol.19 , pp. 30-36
    • Glausier, J.R.1    Fish, K.N.2    Lewis, D.A.3
  • 25
    • 80052449957 scopus 로고    scopus 로고
    • Cortical deficits of glutamic acid decarboxylase 67 expression in schizophrenia: Clinical, protein, and cell type-specific features
    • Curley AA, Arion D, Volk DW, et al: Cortical deficits of glutamic acid decarboxylase 67 expression in schizophrenia: clinical, protein, and cell type-specific features. Am J Psychiatry 2011;168:921-929
    • (2011) Am J Psychiatry , vol.168 , pp. 921-929
    • Curley, A.A.1    Arion, D.2    Volk, D.W.3
  • 26
    • 80052863881 scopus 로고    scopus 로고
    • Conserved interneuronspecific ErbB4 expression in frontal cortex of rodents, monkeys, and humans: Implications for schizophrenia
    • Neddens J, Fish KN, Tricoire L, et al: Conserved interneuronspecific ErbB4 expression in frontal cortex of rodents, monkeys, and humans: implications for schizophrenia. Biol Psychiatry 2011;70:636-645
    • (2011) Biol Psychiatry , vol.70 , pp. 636-645
    • Neddens, J.1    Fish, K.N.2    Tricoire, L.3
  • 27
    • 0036792159 scopus 로고    scopus 로고
    • Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins
    • Beasley CL, Zhang ZJ, Patten I, et al: Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins. Biol Psychiatry 2002;52:708-715
    • (2002) Biol Psychiatry , vol.52 , pp. 708-715
    • Beasley, C.L.1    Zhang, Z.J.2    Patten, I.3
  • 28
    • 84946494256 scopus 로고    scopus 로고
    • Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder
    • Epub ahead of print, Jan 6, 2015
    • Arion D, Corradi JP, Tang S, et al: Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder. Mol Psychiatry (Epub ahead of print, Jan 6, 2015)
    • Mol Psychiatry
    • Arion, D.1    Corradi, J.P.2    Tang, S.3
  • 29
    • 43349105701 scopus 로고    scopus 로고
    • Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia
    • Hashimoto T, Bazmi HH, Mirnics K, et al: Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Am J Psychiatry 2008;165:479-489
    • (2008) Am J Psychiatry , vol.165 , pp. 479-489
    • Hashimoto, T.1    Bazmi, H.H.2    Mirnics, K.3
  • 30
    • 84939870346 scopus 로고    scopus 로고
    • Chemokine receptors and cortical interneuron dysfunction in schizophrenia
    • Epub ahead of print, Nov. 11, 2014
    • Volk DW, Chitrapu A, Edelson JR, et al: Chemokine receptors and cortical interneuron dysfunction in schizophrenia. Schizophr Res (Epub ahead of print, Nov. 11, 2014)
    • Schizophr Res
    • Volk, D.W.1    Chitrapu, A.2    Edelson, J.R.3
  • 31
    • 84891714555 scopus 로고    scopus 로고
    • Lower gene expression for KCNS3 potassium channel subunit in parvalbumin-containing neurons in the prefrontal cortex in schizophrenia
    • Georgiev D, Arion D, Enwright JF, et al: Lower gene expression for KCNS3 potassium channel subunit in parvalbumin-containing neurons in the prefrontal cortex in schizophrenia. Am J Psychiatry 2014;171:62-71
    • (2014) Am J Psychiatry , vol.171 , pp. 62-71
    • Georgiev, D.1    Arion, D.2    Enwright, J.F.3
  • 32
    • 84866518216 scopus 로고    scopus 로고
    • An anatomically comprehensive atlas of the adult human brain transcriptome
    • Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, et al: An anatomically comprehensive atlas of the adult human brain transcriptome. Nature 2012;489:391-399
    • (2012) Nature , vol.489 , pp. 391-399
    • Hawrylycz, M.J.1    Lein, E.S.2    Guillozet-Bongaarts, A.L.3
  • 33
    • 0035179603 scopus 로고    scopus 로고
    • The human temporal cortex: Characterization of neurons expressing nitric oxide synthase, neuropeptides and calcium-binding proteins, and their glutamate receptor subunit profiles
    • González-Albo MC, Elston GN, DeFelipe J: The human temporal cortex: characterization of neurons expressing nitric oxide synthase, neuropeptides and calcium-binding proteins, and their glutamate receptor subunit profiles. Cereb Cortex 2001;11:1170-1181
    • (2001) Cereb Cortex , vol.11 , pp. 1170-1181
    • González-Albo, M.C.1    Elston, G.N.2    DeFelipe, J.3
  • 34
    • 38349091354 scopus 로고    scopus 로고
    • Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia
    • Hashimoto T, Arion D, Unger T, et al: Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia. Mol Psychiatry 2008;13:147-161
    • (2008) Mol Psychiatry , vol.13 , pp. 147-161
    • Hashimoto, T.1    Arion, D.2    Unger, T.3
  • 35
    • 79955775947 scopus 로고    scopus 로고
    • Neuregulin-1 signals from the periphery regulate AMPA receptor sensitivity and expression in GABAergic interneurons in developing neocortex
    • Abe Y, Namba H, Kato T, et al: Neuregulin-1 signals from the periphery regulate AMPA receptor sensitivity and expression in GABAergic interneurons in developing neocortex. J Neurosci 2011;31:5699-5709
    • (2011) J Neurosci , vol.31 , pp. 5699-5709
    • Abe, Y.1    Namba, H.2    Kato, T.3
  • 36
    • 84856293318 scopus 로고    scopus 로고
    • Neuregulin1 regulatesexcitability of fastspiking neurons through Kv1.1 and acts in epilepsy
    • Li KX, Lu YM, Xu ZH, et al: Neuregulin1 regulatesexcitability of fastspiking neurons through Kv1.1 and acts in epilepsy. Nat Neurosci 2012;15:267-273
    • (2012) Nat Neurosci , vol.15 , pp. 267-273
    • Li, K.X.1    Lu, Y.M.2    Xu, Z.H.3
  • 37
    • 84888386051 scopus 로고    scopus 로고
    • ErbB4 reduces synaptic GABAA currents independent of its receptor tyrosine kinase activity
    • Mitchell RM, Janssen MJ, Karavanova I, et al: ErbB4 reduces synaptic GABAA currents independent of its receptor tyrosine kinase activity. Proc Natl Acad Sci USA 2013;110:19603-19608
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 19603-19608
    • Mitchell, R.M.1    Janssen, M.J.2    Karavanova, I.3
  • 38
    • 66649110345 scopus 로고    scopus 로고
    • Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
    • Sohal VS, Zhang F, Yizhar O, et al: Parvalbumin neurons and gamma rhythms enhance cortical circuit performance. Nature 2009;459:698-702
    • (2009) Nature , vol.459 , pp. 698-702
    • Sohal, V.S.1    Zhang, F.2    Yizhar, O.3
  • 39
    • 67650264268 scopus 로고    scopus 로고
    • Neuronal gamma-band synchronization as a fundamental process in cortical computation
    • Fries P: Neuronal gamma-band synchronization as a fundamental process in cortical computation. Annu Rev Neurosci 2009;32:209-224
    • (2009) Annu Rev Neurosci , vol.32 , pp. 209-224
    • Fries, P.1
  • 40
    • 33845945707 scopus 로고    scopus 로고
    • Impairments in frontal cortical gamma synchrony and cognitive control in schizophrenia
    • Cho RY, Konecky RO, Carter CS: Impairments in frontal cortical gamma synchrony and cognitive control in schizophrenia. Proc Natl Acad Sci USA 2006;103:19878-19883
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 19878-19883
    • Cho, R.Y.1    Konecky, R.O.2    Carter, C.S.3


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