Effect of the efflux pump QepA2 combined with chromosomally mediated mechanisms on quinolone resistance and bacterial fitness in Escherichia coli

Journal of Antimicrobial Chemotherapy

Volumn 70, Issue 9, 2015, Pages 2524-2527

  Machuca, Jesús ^a   Briales, Alejandra ^b,c   Díaz de Alba, Paula ^b   Martínez Martínez, Luis ^c,d,e   Pascual, Álvaro ^a,b,c   Rodríguez Martínez, José Manuel ^b,c  

^a HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^e UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

E. coli; qepA; Resistance mechanisms

Indexed keywords

BACTERIAL PROTEIN; CIPROFLOXACIN; NORFLOXACIN; QEPA2 PROTEIN; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL FITNESS; BACTERIAL GENE; BROTH DILUTION; CHROMOSOME; CLINICAL EVALUATION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ELECTROPORATION; ESCHERICHIA COLI; GENE DELETION; GENE MUTATION; HEALTH CARE COST; MICROBIAL ACTIVITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIMARY PREVENTION; QEPA2 GENE; BACTERIAL CHROMOSOME; DRUG EFFECTS; GENETICS; MICROBIAL SENSITIVITY TEST; PHYSIOLOGY; PLASMID; VIRULENCE;

ANTI-BACTERIAL AGENTS; CHROMOSOMES, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; FLUOROQUINOLONES; GENES, BACTERIAL; MICROBIAL SENSITIVITY TESTS; PLASMIDS; VIRULENCE;

EID: 84954288758     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkv144     Document Type: Article

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