Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes

American Journal of Human Genetics

Volumn 98, Issue 1, 2016, Pages 5-21

  Deschamps, Matthieu ^a,b,c   Laval, Guillaume ^a,b   Fagny, Maud ^a,b,c   Itan, Yuval ^d   Abel, Laurent ^d,e   Casanova, Jean Laurent ^d,e,f,g   Patin, Etienne ^a,b   Quintana Murci, Lluis ^a,b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d ROCKEFELLER UNIVERSITY   (United States)

^e IMAGINE INSTITUTE   (France)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^g HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

STAT1 PROTEIN; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 6; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3;

ARTICLE; GENE; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC VARIABILITY; HAPLOTYPE; HOMO NEANDERTHALENSIS; IMMUNE DEFICIENCY; INNATE IMMUNITY; INNATE IMMUNITY GENE; INTROGRESSION; LOCAL ADAPTATION; NEXT GENERATION SEQUENCING; NONHUMAN; PRIORITY JOURNAL; PURIFYING SELECTION; ADAPTATION; ANIMAL; GENETIC SELECTION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; IMMUNOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; IMMUNITY, INNATE; NEANDERTHALS; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION, GENETIC;

EID: 84954288326     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.11.014     Document Type: Article

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