N-acetylcysteine effectively mitigates cadmium-induced oxidative damage and cell death in Leydig cells in vitro

Drug and Chemical Toxicology

Volumn 39, Issue 1, 2016, Pages 74-80

  Khanna, Smita ^a   Mitra, Sumonto ^a   Lakhera, Pramesh C ^b   Khandelwal, Shashi ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b H N B GARHWAL UNIVERSITY   (India)

Author keywords

Cadmium; extracellular signal regulated kinase; Leydig cells; N acetylcysteine; oxidative stress

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ACETYLCYSTEINE; CADMIUM CHLORIDE; CALCIUM ION; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT; CADMIUM; CALCIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CELL ISOLATION; CELL POLARITY; CELL PROTECTION; CELL VIABILITY; CHEMICAL ANALYSIS; CHEMICAL PARAMETERS; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; IN VITRO STUDY; IN VIVO STUDY; LEYDIG CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEPLETION; PROTEIN EXPRESSION; RAT; ANIMAL; DRUG EFFECTS; METABOLISM; MITOCHONDRIAL MEMBRANE; TIME FACTOR; WISTAR RAT;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CADMIUM; CALCIUM; CELL DEATH; GLUTATHIONE; LEYDIG CELLS; MALE; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; TIME FACTORS;

EID: 84954284929     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2015.1028068     Document Type: Article

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