메뉴 건너뛰기




Volumn 55, Issue 1, 2016, Pages 64-76

Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma

Author keywords

Apoptosis; Hepatocellular carcinoma; Oncogene; Prognosis; UBE4B

Indexed keywords

MESSENGER RNA; PROTEIN P53; SMALL INTERFERING RNA; UBIQUITIN; UBIQUITINATION FACTOR E4B; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBE4B PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

EID: 84954228281     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22259     Document Type: Article
Times cited : (23)

References (31)
  • 1
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132:2557-2576.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 3
    • 0034223661 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • discussion1098-1102.
    • Nakakura EK, Choti MA. Management of hepatocellular carcinoma. Oncology (Williston Park) 2000; 14:1085-1098. discussion1098-1102.
    • (2000) Oncology (Williston Park) , vol.14 , pp. 1085-1098
    • Nakakura, E.K.1    Choti, M.A.2
  • 5
    • 0035980094 scopus 로고    scopus 로고
    • U box proteins as a new family of ubiquitin-protein ligases
    • Hatakeyama S, Yada M, Matsumoto M, et al. U box proteins as a new family of ubiquitin-protein ligases. J Biol Chem 2001; 276:33111-33120.
    • (2001) J Biol Chem , vol.276 , pp. 33111-33120
    • Hatakeyama, S.1    Yada, M.2    Matsumoto, M.3
  • 6
    • 0033525589 scopus 로고    scopus 로고
    • A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly
    • Koegl M, Hoppe T, Schlenker S, et al. A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell 1999; 96:635-644.
    • (1999) Cell , vol.96 , pp. 635-644
    • Koegl, M.1    Hoppe, T.2    Schlenker, S.3
  • 8
    • 0029119522 scopus 로고
    • A proteolytic pathway that recognizes ubiquitin as a degradation signal
    • Johnson ES, Ma PC, Ota IM, Varshavsky A. A proteolytic pathway that recognizes ubiquitin as a degradation signal. J Biol Chem 1995; 270:17442-17456.
    • (1995) J Biol Chem , vol.270 , pp. 17442-17456
    • Johnson, E.S.1    Ma, P.C.2    Ota, I.M.3    Varshavsky, A.4
  • 9
    • 27144526164 scopus 로고    scopus 로고
    • Orchestra for assembly and fate of polyubiquitin chains
    • Kuhlbrodt K, Mouysset J, Hoppe T. Orchestra for assembly and fate of polyubiquitin chains. Essays Biochem 2005; 41:1-14.
    • (2005) Essays Biochem , vol.41 , pp. 1-14
    • Kuhlbrodt, K.1    Mouysset, J.2    Hoppe, T.3
  • 11
    • 70450270900 scopus 로고    scopus 로고
    • Awakening guardian angels: drugging the p53 pathway
    • Brown CJ, Lain S, Verma CS, et al. Awakening guardian angels: drugging the p53 pathway. Nat Rev Cancer 2009; 9:862-873.
    • (2009) Nat Rev Cancer , vol.9 , pp. 862-873
    • Brown, C.J.1    Lain, S.2    Verma, C.S.3
  • 12
    • 79952453180 scopus 로고    scopus 로고
    • UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53
    • Wu H, Pomeroy SL, Ferreira M, et al. UBE4B promotes Hdm2-mediated degradation of the tumor suppressor p53. Nat Med 2011; 17:347-355.
    • (2011) Nat Med , vol.17 , pp. 347-355
    • Wu, H.1    Pomeroy, S.L.2    Ferreira, M.3
  • 13
    • 79959217794 scopus 로고    scopus 로고
    • UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation
    • Wu H, Leng RP. UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation. Cell Cycle 2011; 10:1912-1915.
    • (2011) Cell Cycle , vol.10 , pp. 1912-1915
    • Wu, H.1    Leng, R.P.2
  • 14
    • 70349488818 scopus 로고    scopus 로고
    • CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53
    • Shi D, Pop MS, Kulikov R, et al. CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53. Proc Natl Acad Sci USA 2009; 106:16275-16280.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16275-16280
    • Shi, D.1    Pop, M.S.2    Kulikov, R.3
  • 15
    • 38949189642 scopus 로고    scopus 로고
    • Ubiquitin-mediated proteasomal degradation in normal and malignant hematopoiesis
    • Heuze ML, Lamsoul I, Moog-Lutz C, Lutz PG. Ubiquitin-mediated proteasomal degradation in normal and malignant hematopoiesis. Blood Cells Mol Dis 2008; 40:200-210.
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 200-210
    • Heuze, M.L.1    Lamsoul, I.2    Moog-Lutz, C.3    Lutz, P.G.4
  • 16
    • 84896385598 scopus 로고    scopus 로고
    • Regulation of p53 level by UBE4B in breast cancer
    • Zhang Y, Lv Y, Zhang Y, Gao H. Regulation of p53 level by UBE4B in breast cancer. PLoS ONE 2014; 9:e90154.
    • (2014) PLoS ONE , vol.9
    • Zhang, Y.1    Lv, Y.2    Zhang, Y.3    Gao, H.4
  • 17
    • 27944506944 scopus 로고    scopus 로고
    • UFD2a mediates the proteasomal turnover of p73 without promoting p73 ubiquitination
    • Hosoda M, Ozaki T, Miyazaki K, et al. UFD2a mediates the proteasomal turnover of p73 without promoting p73 ubiquitination. Oncogene 2005; 24:7156-7169.
    • (2005) Oncogene , vol.24 , pp. 7156-7169
    • Hosoda, M.1    Ozaki, T.2    Miyazaki, K.3
  • 18
    • 44349118583 scopus 로고    scopus 로고
    • U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha
    • Chatterjee A, Upadhyay S, Chang X, et al. U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha. Cell Cycle 2008; 7:1231-1237.
    • (2008) Cell Cycle , vol.7 , pp. 1231-1237
    • Chatterjee, A.1    Upadhyay, S.2    Chang, X.3
  • 19
    • 18244392443 scopus 로고    scopus 로고
    • Cell death independent of caspases: A review
    • Broker LE, Kruyt FA, Giaccone G. Cell death independent of caspases: A review. Clin Cancer Res 2005; 11:3155-3162.
    • (2005) Clin Cancer Res , vol.11 , pp. 3155-3162
    • Broker, L.E.1    Kruyt, F.A.2    Giaccone, G.3
  • 20
    • 0031987277 scopus 로고    scopus 로고
    • Regulation of p53 downstream genes
    • el-Deiry WS. Regulation of p53 downstream genes. Semin Cancer Biol 1998; 8:345-357.
    • (1998) Semin Cancer Biol , vol.8 , pp. 345-357
    • el-Deiry, W.S.1
  • 21
    • 0028238213 scopus 로고
    • Immediate early up-regulation of bax expression by p53 but not TGF beta 1: A paradigm for distinct apoptotic pathways
    • Selvakumaran M, Lin HK, Miyashita T, et al. Immediate early up-regulation of bax expression by p53 but not TGF beta 1: A paradigm for distinct apoptotic pathways. Oncogene 1994; 9:1791-1798.
    • (1994) Oncogene , vol.9 , pp. 1791-1798
    • Selvakumaran, M.1    Lin, H.K.2    Miyashita, T.3
  • 22
    • 71749086813 scopus 로고    scopus 로고
    • The ubiquitin pathway: An emerging drug target in cancer therapy
    • Ande SR, Chen J, Maddika S. The ubiquitin pathway: An emerging drug target in cancer therapy. Eur J Pharmacol 2009; 625:199-205.
    • (2009) Eur J Pharmacol , vol.625 , pp. 199-205
    • Ande, S.R.1    Chen, J.2    Maddika, S.3
  • 23
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser M. Ubiquitin-dependent protein degradation. Annu Rev Genet 1996; 30:405-439.
    • (1996) Annu Rev Genet , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 24
    • 0029162583 scopus 로고
    • Selective protein degradation: a journey's end within the proteasome
    • Jentsch S, Schlenker S. Selective protein degradation: a journey's end within the proteasome. Cell 1995; 82:881-884.
    • (1995) Cell , vol.82 , pp. 881-884
    • Jentsch, S.1    Schlenker, S.2
  • 25
    • 0028898424 scopus 로고
    • Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade
    • Scheffner M, Nuber U, Huibregtse JM. Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature 1995; 373:81-83.
    • (1995) Nature , vol.373 , pp. 81-83
    • Scheffner, M.1    Nuber, U.2    Huibregtse, J.M.3
  • 26
    • 84873363964 scopus 로고    scopus 로고
    • UBE4B levels are correlated with clinical outcomes in neuroblastoma patients and with altered neuroblastoma cell proliferation and sensitivity to epidermal growth factor receptor inhibitors
    • Zage PE, Sirisaengtaksin N, Liu Y, et al. UBE4B levels are correlated with clinical outcomes in neuroblastoma patients and with altered neuroblastoma cell proliferation and sensitivity to epidermal growth factor receptor inhibitors. Cancer 2013; 119:915-923.
    • (2013) Cancer , vol.119 , pp. 915-923
    • Zage, P.E.1    Sirisaengtaksin, N.2    Liu, Y.3
  • 27
    • 26844489696 scopus 로고    scopus 로고
    • A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation
    • Caren H, Ejeskar K, Fransson S, et al. A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation. Mol Cancer 2005; 4:10.
    • (2005) Mol Cancer , vol.4 , pp. 10
    • Caren, H.1    Ejeskar, K.2    Fransson, S.3
  • 28
    • 0038670768 scopus 로고    scopus 로고
    • Screening for gene mutations in a 500kb neuroblastoma tumor suppressor candidate region in chromosome 1p; mutation and stage-specific expression in UBE4B/UFD2
    • Krona C, Ejeskar K, Abel F, et al. Screening for gene mutations in a 500kb neuroblastoma tumor suppressor candidate region in chromosome 1p; mutation and stage-specific expression in UBE4B/UFD2. Oncogene 2003; 22:2343-2351.
    • (2003) Oncogene , vol.22 , pp. 2343-2351
    • Krona, C.1    Ejeskar, K.2    Abel, F.3
  • 29
    • 84863267267 scopus 로고    scopus 로고
    • Frameshift mutations of ubiquitination-related genes HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B in gastric and colorectal carcinomas with microsatellite instability
    • Yoo NJ, Park SW, Lee SH. Frameshift mutations of ubiquitination-related genes HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B in gastric and colorectal carcinomas with microsatellite instability. Pathology 2011; 43:753-755.
    • (2011) Pathology , vol.43 , pp. 753-755
    • Yoo, N.J.1    Park, S.W.2    Lee, S.H.3
  • 30
    • 58149174212 scopus 로고    scopus 로고
    • Fine deletion analysis of 1p36 chromosomal region in oral squamous cell carcinomas
    • Lefeuvre M, Gunduz M, Nagatsuka H, et al. Fine deletion analysis of 1p36 chromosomal region in oral squamous cell carcinomas. J Oral Pathol Med 2009; 38:94-98.
    • (2009) J Oral Pathol Med , vol.38 , pp. 94-98
    • Lefeuvre, M.1    Gunduz, M.2    Nagatsuka, H.3
  • 31
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.