Real-Time Recording of Circadian Per1 and Per2 Expression in the Suprachiasmatic Nucleus of Freely Moving Rats

Journal of Biological Rhythms

Volumn 31, Issue 1, 2016, Pages 108-111

  Yamaguchi, Yoshiaki ^a,b   Okada, Kazuki ^a   Mizuno, Takanobu ^a   Ota, Takumi ^a   Yamada, Hiroyuki ^a   Doi, M A S A O ^a,b   Kobayashi, Masaki ^c   Tei, Hajime ^d   Shigeyoshi, Yasufumi ^e   Okamura, Hitoshi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOHOKU INSTITUTE OF TECHNOLOGY   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e KINKI UNIVERSITY   (Japan)

Author keywords

circadian; clock gene; optical fiber; period; real time monitoring; suprachiasmatic nucleus

Indexed keywords

CIRCADIAN RHYTHM SIGNALING PROTEIN; LUCIFERASE; PER1 PROTEIN, RAT; PER2 PROTEIN, RAT; TRANSCRIPTION FACTOR;

ANIMAL; CIRCADIAN RHYTHM; CYTOLOGY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; NERVE CELL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SUPRACHIASMATIC NUCLEUS;

ANIMALS; CIRCADIAN RHYTHM; GENE EXPRESSION; GENE EXPRESSION PROFILING; LUCIFERASES; NEURONS; PERIOD CIRCADIAN PROTEINS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; SUPRACHIASMATIC NUCLEUS; TRANSCRIPTION FACTORS;

EID: 84954151533     PISSN: 07487304     EISSN: 15524531     Source Type: Journal    
DOI: 10.1177/0748730415621412     Document Type: Article

References (20)

1. Brancaccio M, Maywood Elizabeth S, Chesham Johanna E, Loudon Andrew SI, Hastings Michael H, (2013) A Gq-Ca2+ axis controls circuit-level encoding of circadian time in the suprachiasmatic nucleus. Neuron 78: 714-728.
2. Hastings MH, Maywood ES, Reddy AB, (2008) Two decades of circadian time. J Neuroendocrinol 20: 812-819.
3. Husse J, Zhou X, Shostak A, Oster H, Eichele G, (2011) Synaptotagmin10-Cre, a driver to disrupt clock genes in the SCN. J Biol Rhythms 26: 379-389.
4. Lee IT, Chang AS, Manandhar M, Shan Y, Fan J, Izumo M, Ikeda Y, Motoike T, Dixon S, Seinfeld JE, et al. (2015) Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms. Neuron 85: 1086-1102.
5. Mieda M, Ono D, Hasegawa E, Okamoto H, Honma K-i, Honma S, Sakurai T, (2015) Cellular clocks in AVP neurons of the SCN are critical for interneuronal coupling regulating circadian behavior rhythm. Neuron 85: 1103-1116.
6. Mohawk JA, Green CB, Takahashi JS, (2012) Central and peripheral circadian clocks in mammals. Annu Rev Neurosci 35: 445-462.
7. Moore RY, Eichler VB, (1972) Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Res 42: 201-206.
8. Okamura H, (2004) Clock genes in cell clocks: roles, actions, and mysteries. J Biol Rhythms 19: 388-399.
9. Ono D, Honma K, Honma S, (2015) Circadian and ultradian rhythms of clock gene expression in the suprachiasmatic nucleus of freely moving mice. Sci Rep 5: 12310.
10. Ralph MR, Foster RG, Davis FC, Menaker M, (1990) Transplanted suprachiasmatic nucleus determines circadian period. Science 247: 975-978.
11. Reppert SM, Weaver DR, (2001) Molecular analysis of mammalian circadian rhythms. Annu Rev Physiol 63: 647-676.
12. Saini C, Liani A, Curie T, Gos P, Kreppel F, Emmenegger Y, Bonacina L, Wolf JP, Poget YA, Franken P, et al. (2013) Real-time recording of circadian liver gene expression in freely moving mice reveals the phase-setting behavior of hepatocyte clocks. Genes Dev 27: 1526-1536.
13. Silver R, Kriegsfeld LJ, (2014) Circadian rhythms have broad implications for understanding brain and behavior. Eur J Neurosci 39: 1866-1880.
14. Stephan FK, Zucker I, (1972) Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions. Proc Natl Acad Sci USA 69: 1583-1586.
15. Sujino M, Masumoto KH, Yamaguchi S, van der Horst GT, Okamura H, Inouye ST, (2003) Suprachiasmatic nucleus grafts restore circadian behavioral rhythms of genetically arrhythmic mice. Curr Biol 13: 664-668.
16. Takahashi JS, Hong HK, Ko CH, McDearmon EL, (2008) The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nature Rev Genet 9: 764-775.
17. Travnickova-Bendova Z, Cermakian N, Reppert SM, Sassone-Corsi P, (2002) Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity. Proc Natl Acad Sci USA 99: 7728-7733.
18. Yamaguchi S, Kobayashi M, Mitsui S, Ishida Y, van der Horst GT, Suzuki M, Shibata S, Okamura H, (2001) View of a mouse clock gene ticking. Nature 409: 684.
19. Yamaguchi S, Mitsui S, Miyake S, Yan L, Onishi H, Yagita K, Suzuki M, Shibata S, Kobayashi M, Okamura H, (2000) The 5′ upstream region of mPer1 gene contains two promoters and is responsible for circadian oscillation. Curr Biol 10: 873-876.
20. Yan L, Takekida S, Shigeyoshi Y, Okamura H, (1999) Per1 and Per2 gene expression in the rat suprachiasmatic nucleus: circadian profile and the compartment-specific response to light. Neuroscience 94: 141-150.