Long-term postoperative azithromycin in patients with chronic rhinosinusitis: A randomized clinical trial

American Journal of Rhinology and Allergy

Volumn 29, Issue 6, 2015, Pages 421-424

  Amali, Amin ^a   Saedi, Babak ^a   Rahavi Ezabadi, Sara ^a   Ghazavi, Hossein ^a   Hassanpoor, Narges ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; FLUTICASONE; PLACEBO; ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHRONIC RHINOSINUSITIS; CHRONIC SINUSITIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; COUGHING; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ENDOSCOPIC SINUS SURGERY; FATIGUE; FEMALE; FOLLOW UP; HEADACHE; HUMAN; LONG TERM CARE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; NASAL LAVAGE; NOSE DISEASE; NOSE OBSTRUCTION; OUTCOME ASSESSMENT; POSTOPERATIVE CARE; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SIDE EFFECT; SLEEP DISORDER; TREATMENT DURATION; CHRONIC DISEASE; DOSE RESPONSE; DRUG ADMINISTRATION; ENDOSCOPY; MIDDLE AGED; PROCEDURES; RECURRENT DISEASE; RETROSPECTIVE STUDY; RHINITIS; SINUSITIS; TIME FACTOR; TREATMENT OUTCOME; YOUNG ADULT;

ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; CHRONIC DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; ENDOSCOPY; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; POSTOPERATIVE CARE; RECURRENCE; RETROSPECTIVE STUDIES; RHINITIS; SINUSITIS; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84954090154     PISSN: 19458924     EISSN: 19458932     Source Type: Journal    
DOI: 10.2500/ajra.2015.29.4244     Document Type: Article

References (24)

1. Pleis JR, Ward BW, and Lucas JW. Summary health statistics for U.S. adults: National Health Interview Survey, 2009. Vital Health Stat 10 (249):1-207, 2010.
2. Gliklich RE, and Metson R. Economic implications of chronic sinusitis. Otolaryngol Head Neck Surg 118:344-349, 1998.
3. Rosenfeld RM, Andes D, Bhattacharyya N, et al. Clinical practice guideline: Adult sinusitis. Otolaryngol Head Neck Surg 137:365-377, 2007.
4. Senior BA, Kennedy DW, Tanabodee J, et al. Long-term results of functional endoscopic sinus surgery. Laryngoscope 108:151-157, 1998.
5. Hopkins C, Slack R, Lund V, et al. Long-term outcomes from the English national comparative audit of surgery for nasal polyposis and chronic rhinosinusitis. Laryngoscope 119:2459-2465, 2009.
6. Levine HL. Functional endoscopic sinus surgery: Evaluation, surgery, and follow-up of 250 patients. Laryngoscope 100:79-84, 1990.
7. Tamaoki J. The effects of macrolides on inflammatory cells. Chest 125(suppl.):41S-50S; quiz 51S, 2004.
8. Suzuki H, Shimomura A, Ikeda K, et al. Inhibitory effect of macro-lides on interleukin-8 secretion from cultured human nasal epithelial cells. Laryngoscope 107:1661-1666, 1997.
9. Bobacheva T. The treatment of chronic polypous rhinosinusitis in the postoperative period with low doses of clarithromycin [in Russian with English abstract]. Vestn Otorinolaringol 4:68-72, 2012.
10. Nakamura Y, Suzuki M, Yokota M, et al. Optimal duration of mac-rolide treatment for chronic sinusitis after endoscopic sinus surgery. Auris Nasus Larynx 40:366-372, 2013.
11. Lund VJ, and Mackay IS. Staging in rhinosinusitis. Rhinology 31:183-184, 1993.
12. Hopkins C, Gillett S, Slack R, et al. Psychometric validity of the 22-item Sinonasal Outcome Test. Clin Otolaryngol 34:447-454, 2009.
13. Kwiatkowska B, and Maslinska M. Macrolide therapy in chronic inflammatory diseases. Mediators Inflamm 2012:636157, 2012.
14. Wong C, Jayaram L, Karalus N, et al. Azithromycin for prevention of exacerbations in non-cystic fibrosis bronchiectasis (EMBRACE): A randomised, double-blind, placebo-controlled trial. Lancet 380:660-667, 2012.
15. Cervin A, and Wallwork B. Anti-inflammatory effects of macrolide antibiotics in the treatment of chronic rhinosinusitis. Otolaryngol Clin North Am 38:1339-1350, 2005.
16. Harvey RJ, Wallwork BD, and Lund VJ. Anti-inflammatory effects of macrolides: Applications in chronic rhinosinusitis. Immunol Allergy Clin North Am 29:689-703, 2009.
17. Majima Y. Clinical implications of the immunomodulatory effects of macrolides on sinusitis. Am J Med 117(suppl. 9A):20S-25S, 2004.
18. Aboud SK, Husain S, and Gendeh BS. Evaluation on quality of life in patients with nasal polyposis managed with optimal medical therapy. Allergy Rhinol (Providence) 5:2-8, 2014.
19. Maniakas A, and Desrosiers M. Azithromycin add-on therapy in high-risk postendoscopic sinus surgery patients failing corticosteroid irrigations: A clinical practice audit. Am J Rhinol Allergy 28:151-155, 2014.
20. Pynnonen MA, Venkamatran G, and Davis GE. Macrolide therapy for chronic rhinosinusitis: A meta-analysis. Otolaryngol Head Neck Surg 148:366-373, 2013.
21. Wallwork B, Coman W, Mackay-Sim A, et al. A double-blind, randomized, placebo-controlled trial of macrolide in the treatment of chronic rhinosinusitis. Laryngoscope 116:189-193, 2006.
22. Amini M, Yarmohammadi M, and Izadi P. A comparing study of clarithromycin XL with co-amoxiclav for treatment of chronic sinusitis: A clinical trial. Iranian J Clin Infect Dis 4:197-201, 2009.
23. Videler WJ, Badia L, Harvey RJ, et al. Lack of efficacy of long-term, low-dose azithromycin in chronic rhinosinusitis: A randomized controlled trial. Allergy 66:1457-1468, 2011.
24. Browne JP, Hopkins C, Slack R, and Cano SJ. The Sino-Nasal Outcome Test (SNOT): Can we make it more clinically meaningful? Otolaryngol Head Neck Surg 136:736-741, 2007.