Relationship between IFNA1, IFNA5, IFNA10, and IFNA17 gene polymorphisms and Crimean-Congo hemorrhagic fever prognosis in a Turkish population range

Journal of Medical Virology

Volumn 88, Issue 7, 2016, Pages 1159-1167

  Elaldi, Nazif ^a   Yilmaz, Meral ^a   Bagci, Binnur ^a   Yelkovan, Izzet ^a   Bagci, Gokhan ^a   Gozel, Mustafa Gokhan ^a   Engin, Aynur ^a   Bakir, Mehmet ^a   Dokmetas, Ilyas ^b  

^a CUMHURIYET UNIVERSITY   (Turkey)

^b SISLI ETFAL TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

CCHF; Gene polymorphism; IFNA1; IFNA17; Turkish population range

Indexed keywords

ALPHA INTERFERON; ALPHA1 INTERFERON; ALPHA10 INTERFERON; ALPHA17 INTERFERON; ALPHA5 INTERFERON; UNCLASSIFIED DRUG; IFNA1 PROTEIN, HUMAN; IFNA10 PROTEIN, HUMAN; IFNA17 PROTEIN, HUMAN; IFNA5 PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ARTICLE; CONTROLLED STUDY; CRIMEAN CONGO HEMORRHAGIC FEVER; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE PREDISPOSITION; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE INTERACTION; GENOTYPE; HAPLOTYPE; HEREDITY; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; IFNA1 GENE; IFNA10 GENE; IFNA17 GENE; IFNA5 GENE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PROGNOSIS; PROSPECTIVE STUDY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVOR; TURKISH CITIZEN; VERY ELDERLY; VIRUS GENE; ALLELE; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MIDDLE AGED; MORTALITY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEMORRHAGIC FEVER, CRIMEAN; HUMANS; INTERFERON-ALPHA; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; TURKEY; YOUNG ADULT;

EID: 84953931343     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.24456     Document Type: Article

References (44)

1. Akahoshi M, Ishihara M, Remus N, Uno K, Miyake K, Hirota T, Nakashima K, Matsuda A, Kanda M, Enomoto T, Ohno S, Nakashima H, Casanova JL, Hopkin JM, Tamari M, Mao XQ, Shirakawa T. 2004. Association between IFNA genotype and the risk of sarcoidosis. Hum Genet 114:503-509.
2. Akinci E, Bodur H, Leblebicioglu H. 2013. Pathogenesis of Crimean-Congo hemorrhagic fever. Vector Borne Zoonotic Dis 13:429-437.
3. Alcaïs A, Abel L, Casanova JL. 2009. Human genetics of infectious diseases: Between proof of principle and paradigm. J Clin Invest 119:2506-2514.
4. Andersson I, Karlberg H, Mousavi-Jazi M, Martínez-Sobrido L, Weber F, Mirazimi A. 2008. Crimean-Congo hemorrhagic fever virus delays activation of the innate immune response. J Med Virol 80:1397-1404.
5. Arslan S, Engin A. 2012. Relationship between NF-κB1 and NF-κBIA genetic polymorphisms and Crimean-Congo hemorrhagic fever. Scand J Infect Dis 44:138-143.
6. Arslan S, Engin A, Özbilum N, Bakir M. 2015. Toll-like receptor 7 Gln11Leu, c.4-151A/G, and +1817G/T polymorphisms in Crimean Congo hemorrhagic fever. J Med Virol 87:1090-1095.
7. Bakir M, Ugurlu M, Dokuzoguz B, Bodur H, Tasyaran MA, Vahaboglu H. 2005. Crimean-Congo haemorrhagic fever outbreak in Middle Anatolia: A multicentre study of clinical features and outcome measures. J Med Microbiol 54:385-389.
8. Bakir M, Bakir S, Sari I, Celik VK, Gozel MG, Engin A. 2013. Evaluation of the relationship between serum levels of VEGF and sVEGFR1 with mortality and prognosis in patients with Crimean-Congo hemorrhagic fever. J Med Virol 85:1794-1801.
9. Bente DA, Alimonti JB, Shieh WJ, Camus G, Ströher U, Zaki S, Jones SM. 2010. Pathogenesis and immune response of Crimean-Congo hemorrhagic fever virus in a STAT-1 knockout mouse model. J Virol 84:11089-11100.
10. Bereczky S, Lindegren G, Karlberg H, Akerström S, Klingström J, Mirazimi A. 2010. Crimean-Congo hemorrhagic fever virus infection is lethal for adult type I interferon receptor-knockout mice. J Gen Virol 91:1473-1477.
11. Bowick GC, Airo AM, Bente DA. 2012. Expression of interferon-induced antiviral genes is delayed in a STAT1 knockout mouse model of Crimean-Congo hemorrhagic fever. Virol J 19:122.
12. Cevik MA, Erbay A, Bodur H, Eren SS, Akinci E, Sener K. 2007. Viral load as a predictor of outcome in Crimean-Congo hemorrhagic fever. Clin Infect Dis 45:96-100.
13. Chan A, Newman DL, Shon AM, Schneider DH, Kuldanek S, Ober C. 2006. Variation in the type I interferon gene cluster on 9p21 influences susceptibility to asthma and atopy. Genes Immun 7:169-178.
14. Chinikar S, Ghiasi SM, Hewson R, Moradi M, Haeri A. 2010. Crimean-Congo hemorrhagic fever in Iran and neighboring countries. J Clin Virol 47:110-114.
15. Connolly-Andersen AM, Douagi I, Kraus AA, Mirazimi A. 2009. Crimean Congo hemorrhagic fever virus infects human monocyte-derived dendritic cells. Virology 390:157-162.
16. Connolly-Andersen AM, Moll G, Andersson C, Åkerström S, Karlberg H, Douagi I, Mirazimi A. 2011. Crimean-Congo hemorrhagic fever virus activates endothelial cells. J Virol 85:7766-7774.
17. Elaldi N, Bodur H, Ascioglu S, Celikbas A, Ozkurt Z, Vahaboglu H, Leblebicioglu H, Yilmaz N, Engin A, Sencan M, Aydin K, Dokmetas I, Cevik MA, Dokuzoguz B, Tasyaran MA, Ozturk R, Bakir M, Uzun R. 2009. Efficacy of oral ribavirin treatment in Crimean-Congo haemorrhagic fever: A quasi-experimental study from Turkey. J Infect 58:238-244.
18. Elaldi N, Kaya S. 2014. Crimean-Congo hemorrhagic fever. J Microbiol Infect Dis (Special Issue 1):S1-S9.
19. Engin A, Arslan S, Kizildag S, Oztürk H, Elaldi N, Dökmetas I, Bakir M. 2010. Toll-like receptor 8 and 9 Polymorphisms in Crimean-Congo hemorrhagic fever. Microbes Infect 12:1071-1078.
20. Fellay J, Shianna KV, Ge D, Colombo S, Ledergerber B, Weale M, Zhang K, Gumbs C, Castagna A, Cossarizza A, Cozzi-Lepri A, De Luca A, Easterbrook P, Francioli P, Mallal S, Martinez-Picado J, Miro JM, Obel N, Smith JP, Wyniger J, Descombes P, Antonarakis SE, Letvin NL, McMichael AJ, Haynes BF, Telenti A, Goldstein DB. 2007. A whole-genome association study of major determinants for host control of HIV-1. Science 317:944-947.
21. Gibbert K, Schlaak JF, Yang D, Dittmer U. 2013. IFN-α subtypes: Distinct biological activities in anti-viral therapy. Br J Pharmacol 168:1048-1058.
22. Golovleva I, Kandefer-Szerszen M, Beckman L, Lundgren E. 1996. Polymorphism in the interferon-α gene family. Am J Hum Genet 59:570-578.
23. Golovleva I, Birgander R, Sjalander A, Lundgren E, Beckman L. 1997. Interferon-α and p53 alleles involved in nasopharngeal carcinoma. Carcinogenesis 18:645-647.
24. Gunes T, Engin A, Poyraz O, Elaldi N, Kaya S, Dokmetas I, Bakir M, Cinar Z. 2009. Crimean-Congo hemorrhagic fever virus in high-risk population, Turkey. Emerg Infect Dis 15:461-464.
25. Hirankarn N, Tangwattanachuleeporn M, Wongpiyabovorn J, Wongchinsri J, Avihingsanon Y. 2008. Genetic association of interferon-alpha subtypes 1, 2 and 5 in systemic lupus erythematosus. Tissue Antigens 72:588-592.
26. Jouanguy E, Zhang SY, Chapgier A, Sancho-Shimizu V, Puel A, Picard C, Boissun-Dupuis S, Abel L, Casanova JL. 2007. Human primary immunodeficiencies of type I interferons. Biochimie 89:878-683.
27. Kaya S, Elaldi N, Kubar A, Gursoy N, Yilmaz M, Karakus G, Gunes T, Polat Z, Gozel MG, Engin A, Dokmetas I, Bakir M, Yilmaz N, Sencan M. 2014. Sequential determination of serum viral titers, virus-specific IgG antibodies, and TNF-α, IL-6, IL-10, and IFN-γ levels in patients with Crimean-Congo hemorrhagic fever. BMC Infect Dis 14:416.
28. Kim JW, Roh JW, Song YS, Kang SB, Lee HP. 2003. Interferon, alpha 17 (IFNA17) Ile184Arg polymorphism and cervical cancer risk. Cancer Lett 189:183-188.
29. Leblebicioglu H. 2010. Crimean-Congo haemorrhagic fever in Eurasia. Int J Antimicrob Agents 36:S43-S46.
30. Leblebicioglu H, Bodur H, Dokuzoguz B, Elaldi N, Guner R, Koksal I, Kurt H, Senturk GC. 2012. Case management and supportive treatment for patients with Crimean-Congo hemorrhagic fever. Vector Borne Zoonotic Dis 12:805-811.
31. Makrythanasis P, Tzetis M, Rapti Papatheodorou AA, Tsipi M, Kitsiou S, Tsiamouri A, Poulou M, Roussos C, Kanavakis E. 2010. Cystic fibrosis conductance regulator, tumor necrosis factor, interferon alpha-10, interferon alpha-17, and interferon gamma genotyping as potential risk markers in pulmonary sarcoidosis pathogenesis in Greek patients. Genet Test Mol Biomarkers 14:577-584.
32. Malmgaard L. 2004. Induction and regulation of IFNs during viral infections. J Interferon Cytokine Res 24:439-454.
33. Mertens M, Schmidt K, Ozkul A, Groschup MH. 2013. The impact of Crimean-Congo hemorrhagic fever virus on public health. Antiviral Res 98:248-260.
34. Nakashima H, Matsuno S, Akahoshi M, Miyake K, Inoue Y, Tanaka Y, Ninomiya I, Shimizu S, Igawa T, Sadanaga A, Otsuka T, Harada M. 2005. Association between IFNA genotype and the risk of systemic lupus erythematosus. Clin Rheumatol 24:38-40.
35. Saksida A, Duh D, Wraber B, Dedushaj I, Ahmeti S, Avsic-Zupanc T. 2010. Interacting roles of immune mechanisms and viral load in the pathogenesis of Crimean-Congo hemorrhagic fever. Clin Vaccine Immunol 17:1086-1093.
36. Sarathy VV, White M, Li L, Gorder SR, Pyles RB, Campbell GA, Milligan GN, Bourne N, Barrett AD. 2015. A lethal murine infection model for dengue virus 3 in AG129 mice deficient in type I and II interferon receptors leads to systemic disease. J Virol 89:1254-1266.
37. Song le H, Toan NL, Xuan NT, Uhlemann AC, Boldt AB, Duy DN, Binh VQ, Kremsner PG, Kun JF. 2006. A promoter polymorphism in the interferon α-2 gene is associated with the clinical presentation of hepatitis B. Mutat Res 601:137-143.
38. Swanepoel R, Gill DE, Shepherd AJ, Leman PA, Mynhardt JH, Harvey S. 1989. The clinical pathology of Crimean-Congo hemorrhagic fever. Rev Infect Dis 11:S794-S800.
39. Tena-Tomás C, de Messias-Reason I, Song le H, Tomiuk J, Kemsner PG, Kun JF. 2008. A globally occurring indel polymorphism in the promoter of the IFNA2 gene is not associated with severity of malaria but with the positivity rate of HCV. BMC Genet 9:80.
40. Trinchieri G. 2010. Type I interferon: Friend or foe? J Exp Med 207:2053-2063.
41. Vorou R, Pierroutsakos IN, Maltezou HC. 2007. Crimean-Congo hemorrhagic fever. Curr Opinion Infect Dis 20:495-500.
42. Whitehouse CA. 2004. Crimean-Congo hemorrhagic fever. Antiviral Res 64:145-160.
43. Yapar M, Aydogan H, Pahsa A, Besirbellioglu BA, Bodur H, Basustaoglu AC, Guney C, Avci IY, Sener K, Setteh MH, Kubar A. 2005. Rapid and quantitative detection of Crimean-Congo hemorrhagic fever virus by one-step real-time reverse transcriptase-PCR. Jpn J Infect Dis 58:358-362.
44. Yilmaz M, Elaldi N, Bagci B, Sari I, Gümüs E, Yelkovan I. 2015. Effect of tumour necrosis factor-alpha and interleukin-6 promoter polymorphisms on course of Crimean-Congo hemorrhagic fever in Turkish patients. J Vector Borne Dis 52:30-35.