Lipid-based nutrient supplements for pregnant women reduce newborn stunting in a cluster-randomized controlled effectiveness trial in Bangladesh

American Journal of Clinical Nutrition

Volumn 103, Issue 1, 2016, Pages 236-249

  Mridha, Malay K ^a,c   Matias, Susana L ^a   Chaparro, Camila M ^d   Paul, Rina R ^c,f   Hussain, Sohrab ^c,g   Vosti, Stephen A ^a   Harding, Kassandra L ^a   Cummins, Joseph R ^b   Day, Louise T ^e   Saha, Stacy L ^e   Peerson, Janet M ^a   Dewey, Kathryn G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

^d Consultant ^*  (United States)

^e LAMB   (Bangladesh)

^f CARE (Cooperative for Assistance and Relief Everywhere) Bangladesh   (Bangladesh)

^g SAVE THE CHILDREN   (United Kingdom)

Author keywords

Head circumference; Iron and folic acid; Lipid based nutrient supplements; Low birth weight; Newborn stunting

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CALCIUM; COPPER; CYANOCOBALAMIN; ESSENTIAL FATTY ACID; FAT; FOLIC ACID; IODINE; IRON; LINOLEIC ACID; LINOLENIC ACID; MAGNESIUM; MANGANESE; NICOTINIC ACID; PANTOTHENIC ACID; PHOSPHORUS; POTASSIUM; PYRIDOXINE; RETINOL; SELENIUM; THIAMINE; TRACE ELEMENT; VITAMIN D; VITAMIN K GROUP; ZINC; FAT INTAKE;

ADULT; ARTICLE; BANGLADESH; BIRTH WEIGHT; BODY HEIGHT; BODY MASS; CEPHALOMETRY; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; COMPARATIVE STUDY; CONTROLLED STUDY; DIET SUPPLEMENTATION; EDUCATIONAL STATUS; FEMALE; FOLLOW UP; FOOD INSECURITY; FOOD SECURITY; GESTATIONAL AGE; HEAD CIRCUMFERENCE; HUMAN; INFANT; IRON THERAPY; LIPID BASED NUTRIENT SUPPLEMENT; LIVE BIRTH; MALNUTRITION; MATERNAL AGE; MATERNAL MORTALITY; MATERNAL NUTRITION; NEWBORN DISEASE; NEWBORN MORTALITY; NEWBORN STUNTING; NUTRITIONAL STATUS; PATIENT COMPLIANCE; PREGNANCY OUTCOME; PREGNANT WOMAN; PREMATURE LABOR; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; STILLBIRTH; STUNTING; YOUNG ADULT; ADOLESCENT; COMPLICATION; CONTROLLED CLINICAL TRIAL; DIETARY SUPPLEMENT; DRUG EFFECTS; FAT INTAKE; FETAL GROWTH RETARDATION; FETUS DEVELOPMENT; GROWTH DISORDERS; LACTATION; NEWBORN; PHARMACOLOGY; PREGNANCY; THERAPEUTIC USE;

ADOLESCENT; ADULT; BANGLADESH; BIRTH WEIGHT; BODY HEIGHT; DIETARY FATS; DIETARY SUPPLEMENTS; FEMALE; FETAL DEVELOPMENT; FETAL GROWTH RETARDATION; GROWTH DISORDERS; HUMANS; INFANT, NEWBORN; LACTATION; MALNUTRITION; MICRONUTRIENTS; PREGNANCY; PRENATAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; YOUNG ADULT;

EID: 84953854013     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.115.111336     Document Type: Article

References (38)

1. Christian P, Lee SE, Donahue Angel M, Adair LS, Arifeen SE, Ashorn P, Barros FC, Fall CH, Fawzi WW, Hao W, et al. Risk of childhood undernutrition related to small-for-gestational age and preterm birth in low-and middle-income countries. Int J Epidemiol 2013;42: 1340-55.
2. National Low Birth Weight Survey of Bangladesh, 2003-2004. Dhaka (Bangladesh): Bangladesh Bureau of Statistics and United Nations Children's Fund; 2005.
3. Bangladesh Demographic and Health Survey 2014: key indicators. Dhaka (Bangladesh) and Rockville (MD): National Institute of Population Research and Training, Mitra and Associates, and ICF International; 2015.
4. Alam DS. Prevention of low birthweight. Nestle Nutr Workshop Ser Pediatr Program 2009;63:209-21; discussion: 21-5, 59-68.
5. Alderman H, Behrman JR. Estimated economic benefits of reducing low birth weight in low-income countries. Washington (DC): The World Bank; 2004. Contract No.: 35548.
6. Abu-Saad K, Fraser D. Maternal nutrition and birth outcomes. Epidemiol Rev 2010;32:5-25.
7. Arsenault JE, Yakes EA, Islam MM, Hossain MB, Ahmed T, Hotz C, Lewis B, Rahman AS, Jamil KM, Brown KH. Very low adequacy of micronutrient intakes by young children and women in rural Bangla-desh is primarily explained by low food intake and limited diversity. J Nutr 2013;143:197-203.
8. Peña-Rosas JP, De-Regil LM, Dowswell T, Viteri FE. Intermittent oral iron supplementation during pregnancy. Cochrane Database Syst Rev 2012;7:CD009997.
9. Imdad A, Bhutta ZA. Maternal nutrition and birth outcomes: effect of balanced protein-energy supplementation. Paediatr Perinat Epidemiol 2012;26(Suppl 1):178-90.
10. Ramakrishnan U, Grant FK, Goldenberg T, Bui V, Imdad A, Bhutta ZA. Effect of multiple micronutrient supplementation on pregnancy and infant outcomes: a systematic review. Paediatr Perinat Epidemiol 2012;26 (Suppl 1):153-67.
11. West KP Jr., Shamim AA, Mehra S, Labrique AB, Ali H, Shaikh S, Klemm RDW, Wu LSF, Mitra M, Haque R, et al. Effect of maternal multiple micronutrient vs iron-folic acid supplementation on infant mortality and adverse birth outcomes in rural Bangladesh: the JiVitA-3 randomized trial. JAMA 2014;312:2649-58.
12. Arimond M, Zeilani M, Jungjohann S, Brown KH, Ashorn P, Allen LH, Dewey KG. Considerations in developing lipid-based nutrient supplements for prevention of undernutrition: experience from the International Lipid-Based Nutrient Supplements (iLiNS) Project. Matern Child Nutr 2013 May 6 (Epub ahead of print; DOI: 10.1111/mcn.12049).
13. Adu-Afarwuah S, Lartey A, Brown KH, Zlotkin S, Briend A, Dewey KG. Randomized comparison of 3 types of micronutrient supplements for home fortification of complementary foods in Ghana: effects on growth and motor development. Am J Clin Nutr 2007;86: 412-20.
14. Adu-Afarwuah S, Lartey A, Brown KH, Zlotkin S, Briend A, Dewey KG. Home fortification of complementary foods with micronutrient sup-plements is well accepted and has positive effects on infant iron status in Ghana. Am J Clin Nutr 2008;87:929-38.
15. Mridha MK, Chaparro CM, Matias SL, Hussain S, Munira S, Saha S, Day LT, Dewey KG. Acceptability of lipid-based nutrient supplements and micronutrient powders among pregnant and lactat-ing women and infants and young children in Bangladesh and their perceptions about malnutrition and nutrient supplements. Washington (DC): University of California, Davis; FANTA-2 Bridge; ICDDR, B; World Mission Prayer League (LAMB Hospital); 2012.
16. Bangladesh Population and Housing Census [Internet]. [cited 2014 Jun 6]. Bangladesh Bureau of Statistics; 2011. Available from: http://203.112.218.66/PageWebMenuContent.aspx?MenuKey=480 and http://203.112.218.66/PageWebMenuContent.aspx?MenuKey=474.
17. Sebayang SK, Dibley MJ, Kelly PJ, Shankar AV, Shankar AH. De-terminants of low birthweight, small-for-gestational-age and preterm birth in Lombok, Indonesia: analyses of the birthweight cohort of the SUMMIT trial. Trop Med Int Health 2012;17:938-50.
18. Kaestel P, Michaelsen KF, Aaby P, Friis H. Effects of prenatal multi-micronutrient supplements on birth weight and perinatal mortality: a randomised, controlled trial in Guinea-Bissau. Eur J Clin Nutr 2005; 59:1081-9.
19. World Health Organization. WHO guidelines: daily iron and folic acid supplementation in pregnant women. Geneva (Switzerland): World Health Organization; 2012.
20. Centers for Disease Control and Prevention. Cronobacter [updated 2014 Feb 12; cited 2014 Jun 6]. Available from: http://www.cdc.gov/cronobacter/technical.html.
21. de Onis M, Onyango AW, Van den Broeck J, Chumlea WC, Martorell R. Measurement and standardization protocols for anthropometry used in the construction of a new international growth reference. Food Nutr Bull 2004;25(1 Suppl):S27-36.
22. World Health Organization. WHO Child Growth Standards. WHO Anthro (version 3.2.2, January 2011) and macros [cited 2014 Jun 6]. Available from: http://www.who.int/childgrowth/software/en/.
23. World Health Organization. WHO Child Growth Standards. Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. Geneva (Switzerland): World Health Organization; 2006.
24. Alexander GR, Himes JH, Kaufman RB, Mor J, Kogan M. A United States national reference for fetal growth. Obstet Gynecol 1996;87: 163-8.
25. Coates J, Swindale A, Bilinsky P. Household Food Insecurity Access Scale (HFIAS) for Measurement of Household Food Access: Indicator Guide. Version 3. Washington (DC): Food and Nutrition Technical Assistance Project, Academy for Educational Development; 2007.
26. Streiner DL. Best (but oft-forgotten) practices: the multiple problems of multiplicity-whether and how to correct for many statistical tests. Am J Clin Nutr 2015;102:721-8.
27. Harding KL, Matias SL, Moniruzzaman M, Stewart CP, Mridha MK, Vosti SA, Dewey KG. Rang-Din Nutrition Study: assessment of participant adherence to lipid-based nutrient and iron-folic acid supplements among pregnant and lactating women in the context of a study on the effectiveness of supplements in Bangladesh. Washington (DC): Family Health International 360/Food and Nutrition Technical Assistance; 2014.
28. de Onis M, Dewey KG, Borghi E, Onyango AW, Blossner M, Daelmans B, Piwoz E, Branca F. The World Health Organization's global target for reducing childhood stunting by 2025: rationale and proposed actions. Matern Child Nutr 2013;9(Suppl 2):6-26.
29. Martorell R, Zongrone A. Intergenerational influences on child growth and undernutrition. Paediatr Perinat Epidemiol 2012;26(Suppl 1):302-14.
30. Fall CH, Fisher DJ, Osmond C, Margetts BM. Multiple micronutrient supplementation during pregnancy in low-income countries: a meta-analysis of effects on birth size and length of gestation. Food Nutr Bull 2009;30(4 Suppl):S533-46.
31. Kramer MS, Kakuma R. Energy and protein intake in pregnancy. Cochrane Database Syst Rev 2003;4:CD000032.
32. Huybregts L, Roberfroid D, Lanou H, Menten J, Meda N, Van Camp J, Kolsteren P. Prenatal food supplementation fortified with multiple micronutrients increases birth length: a randomized controlled trial in rural Burkina Faso. Am J Clin Nutr 2009;90:1593-600.
33. Lorenz JM, Whitaker AH, Feldman JF, Yudkin PL, Shen S, Blond A, Pinto-Martin JA, Paneth N. Indices of body and brain size at birth and at the age of 2 years: relations to cognitive outcome at the age of 16 years in low birth weight infants. J Dev Behav Pediatr 2009;30:535-43.
34. Bhutta ZA, Rizvi A, Raza F, Hotwani S, Zaidi S, Moazzam Hossain S, Soofi S, Bhutta S. A comparative evaluation of multiple micro-nutrient and iron-folic acid supplementation during pregnancy in Pakistan: impact on pregnancy outcomes. Food Nutr Bull 2009;30(4 Suppl): S496-505.
35. Sunawang, Utomo B, Hidayat A, Kusharisupeni, Subarkah. Preventing low birthweight through maternal multiple micro-nutrient supplementation: a cluster-randomized, controlled trial in Indramayu, West Java. Food Nutr Bull 2009;30(4 Suppl): S488-95.
36. Lu WP, Lu MS, Li ZH, Zhang CX. Effects of multimicronutrient supplementation during pregnancy on postnatal growth of children under 5 years of age: a meta-analysis of randomized controlled trials. PLoS One 2014;9:e88496.
37. Rah JH, Christian P, Shamim AA, Arju UT, Labrique AB, Rashid M. Pregnancy and lactation hinder growth and nutritional status of ado-lescent girls in rural Bangladesh. J Nutr 2008;138:1505-11.
38. King JC. The risk of maternal nutritional depletion and poor out-comes increases in early or closely spaced pregnancies. J Nutr 2003; 133(5 Suppl 2):1732S-6S.