-
1
-
-
84872735966
-
Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells
-
Mayer ML, Blohmke CJ, FalsafiR, Fjell CD, Madera L, Turvey SE, Hancock RE. Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells. J Immunol 2013; 190:1227-38.
-
(2013)
J Immunol
, vol.190
, pp. 1227-1238
-
-
Mayer, M.L.1
Blohmke, C.J.2
Falsafi, R.3
Fjell, C.D.4
Madera, L.5
Turvey, S.E.6
Hancock, R.E.7
-
2
-
-
0033831270
-
Exaggerated activation of nuclear factor-kappab and altered ikappab-beta processing in cystic fibrosis bronchial epithelial cells
-
Venkatakrishnan A, Stecenko AA, King G, Blackwell TR, Brigham KL, Christman JW, Blackwell TS. Exaggerated activation of nuclear factor-kappab and altered ikappab-beta processing in cystic fibrosis bronchial epithelial cells. Am J Respir Cell Mol Biol 2000; 23:396-403.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, pp. 396-403
-
-
Venkatakrishnan, A.1
Stecenko, A.A.2
King, G.3
Blackwell, T.R.4
Brigham, K.L.5
Christman, J.W.6
Blackwell, T.S.7
-
4
-
-
84878640144
-
Contribution of CFTR to alveolar fluid clearance by lipoxin a4 via pi3k/AKT pathway in LPS-induced acute lung injury
-
Yang Y, Cheng Y, Lian QQ, Yang L, Qi W, Wu DR, et al. Contribution of CFTR to alveolar fluid clearance by lipoxin a4 via pi3k/AKT pathway in LPS-induced acute lung injury. Mediators Inflamm 2013; 2013:862628.
-
(2013)
Mediators Inflamm
, vol.2013
-
-
Yang, Y.1
Cheng, Y.2
Lian, Q.Q.3
Yang, L.4
Qi, W.5
Wu, D.R.6
-
5
-
-
84868322168
-
Absence of the cystic fibrosis transmembrane regulator (CFTR) from myeloid-derived cells slows resolution of inflammation and infection
-
Bonfield TL, Hodges CA, Cotton CU, Drumm ML. Absence of the cystic fibrosis transmembrane regulator (CFTR) from myeloid-derived cells slows resolution of inflammation and infection. J Leukoc Biol 2012; 92:1111-22.
-
(2012)
J Leukoc Biol
, vol.92
, pp. 1111-1122
-
-
Bonfield, T.L.1
Hodges, C.A.2
Cotton, C.U.3
Drumm, M.L.4
-
6
-
-
79960641412
-
Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis
-
Sorio C, Buffelli M, Angiari C, Ettorre M, Johansson J, Vezzalini M, et al. Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis. PLoS One 2011; 6:e22212.
-
(2011)
PLoS One
, vol.6
-
-
Sorio, C.1
Buffelli, M.2
Angiari, C.3
Ettorre, M.4
Johansson, J.5
Vezzalini, M.6
-
7
-
-
80051663317
-
Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice
-
Su X, Looney MR, Su HE, Lee JW, Song Y, Matthay MA. Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice. Inflamm Res 2011; 60:619-32.
-
(2011)
Inflamm Res
, vol.60
, pp. 619-632
-
-
Su, X.1
Looney, M.R.2
Su, H.E.3
Lee, J.W.4
Song, Y.5
Matthay, M.A.6
-
8
-
-
84893189031
-
Important role of platelets in modulating endotoxin-induced lung inflammation in CFTR-deficient mice
-
Zhao C, Su EM, Yang X, Gao Z, Li L, Wu H, et al. Important role of platelets in modulating endotoxin-induced lung inflammation in CFTR-deficient mice. PLoS One 2013; 8:e82683.
-
(2013)
PLoS One
, vol.8
-
-
Zhao, C.1
Su, E.M.2
Yang, X.3
Gao, Z.4
Li, L.5
Wu, H.6
-
9
-
-
84899797428
-
Lipoxin a4 and platelet activating factor are involved in E. coli or LPS-induced lung inflammation in CFTR-deficient mice
-
Wu H, Yang J, Su EM, Li L, Zhao C, Yang X, et al. Lipoxin a4 and platelet activating factor are involved in E. coli or LPS-induced lung inflammation in CFTR-deficient mice. PLoS One 2014; 9: e93003.
-
(2014)
PLoS One
, vol.9
-
-
Wu, H.1
Yang, J.2
Su, E.M.3
Li, L.4
Zhao, C.5
Yang, X.6
-
10
-
-
33748146503
-
CFTR regulates phagosome acidification in macrophages and alters bactericidal activity
-
Di A, Brown ME, Deriy LV, Li C, Szeto FL, Chen Y, et al. CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. Nat Cell Biol 2006; 8:933-44.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 933-944
-
-
Di, A.1
Brown, M.E.2
Deriy, L.V.3
Li, C.4
Szeto, F.L.5
Chen, Y.6
-
11
-
-
20444431221
-
Platelet activation in cystic fibrosis
-
O'Sullivan BP, Linden MD, Frelinger AL 3rd, Barnard MR, Spencer-Manzon M, Morris JE, et al. Platelet activation in cystic fibrosis. Blood 2005; 105:4635-41.
-
(2005)
Blood
, vol.105
, pp. 4635-4641
-
-
O'Sullivan, B.P.1
Linden, M.D.2
Frelinger, A.L.3
Barnard, M.R.4
Spencer-Manzon, M.5
Morris, J.E.6
-
12
-
-
77957853687
-
Cystic fibrosis transmembrane conductance regulator (CFTR) expression in human platelets: impact on mediators and mechanisms of the inflammatory response
-
Mattoscio D, Evangelista V, De Cristofaro R, Recchiuti A, PandolfiA, Di Silvestre S, et al. Cystic fibrosis transmembrane conductance regulator (CFTR) expression in human platelets: impact on mediators and mechanisms of the inflammatory response. FASEB J 2010; 24:3970-80.
-
(2010)
FASEB J
, vol.24
, pp. 3970-3980
-
-
Mattoscio, D.1
Evangelista, V.2
De Cristofaro, R.3
Recchiuti, A.4
Pandolfi, A.5
Di Silvestre, S.6
-
13
-
-
0035148744
-
Septic shock and acute lung injury in rabbits with peritonitis: failure of the neutrophil response to localized infection
-
Matute-Bello G, Frevert CW, Kajikawa O, Skerrett SJ, Goodman RB, Park DR, et al. Septic shock and acute lung injury in rabbits with peritonitis: failure of the neutrophil response to localized infection. Am J Respir Crit Care Med 2001; 163:234-43.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 234-243
-
-
Matute-Bello, G.1
Frevert, C.W.2
Kajikawa, O.3
Skerrett, S.J.4
Goodman, R.B.5
Park, D.R.6
-
14
-
-
4143050532
-
Direct visual instillation as a method for efficient delivery of fluid into the distal airspaces of anesthetized mice
-
Su X, Looney M, Robriquet L, Fang X, Matthay MA. Direct visual instillation as a method for efficient delivery of fluid into the distal airspaces of anesthetized mice. Exp Lung Res 2004; 30:479-93.
-
(2004)
Exp Lung Res
, vol.30
, pp. 479-493
-
-
Su, X.1
Looney, M.2
Robriquet, L.3
Fang, X.4
Matthay, M.A.5
-
15
-
-
73949141883
-
Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury
-
Su X, Matthay MA, Malik AB. Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury. J Immunol 2010; 184:401-10.
-
(2010)
J Immunol
, vol.184
, pp. 401-410
-
-
Su, X.1
Matthay, M.A.2
Malik, A.B.3
-
16
-
-
34547867437
-
Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats
-
Su X, Lee JW, Matthay ZA, Mednick G, Uchida T, Fang X, et al. Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats. Am J Respir Cell Mol Biol 2007; 37: 186-92.
-
(2007)
Am J Respir Cell Mol Biol
, vol.37
, pp. 186-192
-
-
Su, X.1
Lee, J.W.2
Matthay, Z.A.3
Mednick, G.4
Uchida, T.5
Fang, X.6
-
17
-
-
84866406357
-
Leading neutrophils to the alveoli: who is the guider?
-
Su X. Leading neutrophils to the alveoli: who is the guider? Am J Respir Crit Care Med 2012; 186:472-3.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 472-473
-
-
Su, X.1
-
19
-
-
30944432774
-
Calcium-dependent regulation of nf-(kappa)b activation in cystic fibrosis airway epithelial cells
-
Tabary O, Boncoeur E, de Martin R, Pepperkok R, Clement A, Schultz C, et al. Calcium-dependent regulation of nf-(kappa)b activation in cystic fibrosis airway epithelial cells. Cell Signal 2006; 18:652-60.
-
(2006)
Cell Signal
, vol.18
, pp. 652-660
-
-
Tabary, O.1
Boncoeur, E.2
de Martin, R.3
Pepperkok, R.4
Clement, A.5
Schultz, C.6
-
20
-
-
84859620802
-
Cystic fibrosis: a mucosal immunodeficiency syndrome
-
Cohen TS, Prince A. Cystic fibrosis: a mucosal immunodeficiency syndrome. Nat Med 2012; 18:509-19.
-
(2012)
Nat Med
, vol.18
, pp. 509-519
-
-
Cohen, T.S.1
Prince, A.2
-
21
-
-
34247557545
-
Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways
-
Verhaeghe C, Remouchamps C, Hennuy B, Vanderplasschen A, Chariot A, Tabruyn SP, et al. Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. Biochem Pharmacol 2007; 73:1982-94.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 1982-1994
-
-
Verhaeghe, C.1
Remouchamps, C.2
Hennuy, B.3
Vanderplasschen, A.4
Chariot, A.5
Tabruyn, S.P.6
-
22
-
-
61549139061
-
Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/-mice
-
Bruscia EM, Zhang PX, Ferreira E, Caputo C, Emerson JW, Tuck D, et al. Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/-mice. Am J Respir Cell Mol Biol 2009; 40:295-304.
-
(2009)
Am J Respir Cell Mol Biol
, vol.40
, pp. 295-304
-
-
Bruscia, E.M.1
Zhang, P.X.2
Ferreira, E.3
Caputo, C.4
Emerson, J.W.5
Tuck, D.6
-
23
-
-
84920412587
-
Cystic fibrosis foundation pulmonary clinical practice guidelines C. Cystic fibrosis foundation pulmonary guideline. Pharmacologic approaches to prevention and eradication of initial pseudomonas aeruginosa infection
-
Mogayzel PJ Jr, Naureckas ET, Robinson KA, Brady C, Guill M, Lahiri T, et al. Cystic fibrosis foundation pulmonary clinical practice guidelines C. Cystic fibrosis foundation pulmonary guideline. Pharmacologic approaches to prevention and eradication of initial pseudomonas aeruginosa infection. Ann Am Thorac Soc 2014; 11:1640-50.
-
(2014)
Ann Am Thorac Soc
, vol.11
, pp. 1640-1650
-
-
Mogayzel, P.J.1
Naureckas, E.T.2
Robinson, K.A.3
Brady, C.4
Guill, M.5
Lahiri, T.6
-
24
-
-
84928943687
-
A novel regulator of lung inflammation and immunity: pulmonary parasympathetic inflammatory reflex
-
Yang X, Zhao C, Gao Z, Su X. A novel regulator of lung inflammation and immunity: pulmonary parasympathetic inflammatory reflex. QJM 2014; 107:789-92.
-
(2014)
QJM
, vol.107
, pp. 789-792
-
-
Yang, X.1
Zhao, C.2
Gao, Z.3
Su, X.4
-
25
-
-
2942544512
-
Toll-like receptors in normal and cystic fibrosis airway epithelial cells
-
Muir A, Soong G, Sokol S, Reddy B, Gomez MI, Van Heeckeren A, et al. Toll-like receptors in normal and cystic fibrosis airway epithelial cells. Am J Respir Cell Mol Biol 2004; 30:777-83.
-
(2004)
Am J Respir Cell Mol Biol
, vol.30
, pp. 777-783
-
-
Muir, A.1
Soong, G.2
Sokol, S.3
Reddy, B.4
Gomez, M.I.5
Van Heeckeren, A.6
-
26
-
-
84874594757
-
Toll-like receptor 4 is not targeted to the lysosome in cystic fibrosis airway epithelial cells
-
Kelly C, Canning P, Buchanan PJ, Williams MT, Brown V, Gruenert DC, et al. Toll-like receptor 4 is not targeted to the lysosome in cystic fibrosis airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 2013; 304:L371-82.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.304
, pp. L371-L382
-
-
Kelly, C.1
Canning, P.2
Buchanan, P.J.3
Williams, M.T.4
Brown, V.5
Gruenert, D.C.6
-
27
-
-
77954603744
-
Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to pseudomonas aeruginosa
-
Berube J, Roussel L, Nattagh L, Rousseau S. Loss of cystic fibrosis transmembrane conductance regulator function enhances activation of p38 and ERK MAPKs, increasing interleukin-6 synthesis in airway epithelial cells exposed to pseudomonas aeruginosa. J Biol Chem 2010; 285: 22299-307.
-
(2010)
J Biol Chem
, vol.285
, pp. 22299-22307
-
-
Berube, J.1
Roussel, L.2
Nattagh, L.3
Rousseau, S.4
-
28
-
-
84869785004
-
Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 mapkmediated innate immune responses
-
Blohmke CJ, Mayer ML, Tang AC, Hirschfeld AF, Fjell CD, Sze MA, et al. Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 mapkmediated innate immune responses. J Immunol 2012; 189: 5467-75.
-
(2012)
J Immunol
, vol.189
, pp. 5467-5475
-
-
Blohmke, C.J.1
Mayer, M.L.2
Tang, A.C.3
Hirschfeld, A.F.4
Fjell, C.D.5
Sze, M.A.6
-
29
-
-
84864288310
-
CFTR is a negative regulator of nfkappab mediated innate immune response
-
Vij N, Mazur S, Zeitlin PL. CFTR is a negative regulator of nfkappab mediated innate immune response. PLoS One 2009; 4:e4664.
-
(2009)
PLoS One
, vol.4
-
-
Vij, N.1
Mazur, S.2
Zeitlin, P.L.3
-
30
-
-
0037083448
-
Functional IL-10 deficiency in the lung of cystic fibrosis (CFTR(-/-)) and IL-10 knockout mice causes increased expression and function of b7 costimulatory molecules on alveolar macrophages
-
Soltys J, Bonfield T, Chmiel J, Berger M. Functional IL-10 deficiency in the lung of cystic fibrosis (CFTR(-/-)) and IL-10 knockout mice causes increased expression and function of b7 costimulatory molecules on alveolar macrophages. J Immunol 2002; 168:1903-10.
-
(2002)
J Immunol
, vol.168
, pp. 1903-1910
-
-
Soltys, J.1
Bonfield, T.2
Chmiel, J.3
Berger, M.4
-
31
-
-
0028784322
-
Inflammatory cytokines in cystic fibrosis lungs
-
Bonfield TL, Panuska JR, Konstan MW, Hilliard KA, Hilliard JB, Ghnaim H, et al. Inflammatory cytokines in cystic fibrosis lungs. Am J Respir Crit Care Med 1995; 152:2111-8.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 2111-2118
-
-
Bonfield, T.L.1
Panuska, J.R.2
Konstan, M.W.3
Hilliard, K.A.4
Hilliard, J.B.5
Ghnaim, H.6
-
32
-
-
0029372481
-
Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis
-
Bonfield TL, Konstan MW, Burfeind P, Panuska JR, Hilliard JB, Berger M. Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis. Am J Respir Cell Mol Biol 1995; 13:257-61.
-
(1995)
Am J Respir Cell Mol Biol
, vol.13
, pp. 257-261
-
-
Bonfield, T.L.1
Konstan, M.W.2
Burfeind, P.3
Panuska, J.R.4
Hilliard, J.B.5
Berger, M.6
-
33
-
-
33751177801
-
Azithromycin reduces spontaneous and induced inflammation in deltaf508 cystic fibrosis mice
-
Legssyer R, Huaux F, Lebacq J, Delos M, Marbaix E, Lebecque P, et al. Azithromycin reduces spontaneous and induced inflammation in deltaf508 cystic fibrosis mice. Respir Res 2006; 7:134.
-
(2006)
Respir Res
, vol.7
, pp. 134
-
-
Legssyer, R.1
Huaux, F.2
Lebacq, J.3
Delos, M.4
Marbaix, E.5
Lebecque, P.6
-
34
-
-
84920724791
-
Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment
-
Lavin Y, Winter D, Blecher-Gonen R, David E, Keren-Shaul H, Merad M, et al. Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell 2014; 159:1312-26.
-
(2014)
Cell
, vol.159
, pp. 1312-1326
-
-
Lavin, Y.1
Winter, D.2
Blecher-Gonen, R.3
David, E.4
Keren-Shaul, H.5
Merad, M.6
-
35
-
-
84920724792
-
Environment drives selection and function of enhancers controlling tissue-specific macrophage identities
-
Gosselin D, Link VM, Romanoski CE, Fonseca GJ, Eichenfield DZ, Spann NJ, et al. Environment drives selection and function of enhancers controlling tissue-specific macrophage identities. Cell 2014; 159:1327-40.
-
(2014)
Cell
, vol.159
, pp. 1327-1340
-
-
Gosselin, D.1
Link, V.M.2
Romanoski, C.E.3
Fonseca, G.J.4
Eichenfield, D.Z.5
Spann, N.J.6
-
36
-
-
84861951340
-
Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and Nf-kB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury
-
Lee YJ, Han JY, Byun J, Park HJ, Park EM, Chong YH, et al. Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and Nf-kB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury. J Leukoc Biol 2012; 91:921-32.
-
(2012)
J Leukoc Biol
, vol.91
, pp. 921-932
-
-
Lee, Y.J.1
Han, J.Y.2
Byun, J.3
Park, H.J.4
Park, E.M.5
Chong, Y.H.6
-
37
-
-
78650645373
-
Ceramide and ceramide 1-phosphate are negative regulators of TNF-alpha production induced by lipopolysaccharide
-
Jozefowski S, Czerkies M, Lukasik A, Bielawska A, Bielawski J, Kwiatkowska K, et al. Ceramide and ceramide 1-phosphate are negative regulators of TNF-alpha production induced by lipopolysaccharide. J Immunol 2010; 185:6960-73.
-
(2010)
J Immunol
, vol.185
, pp. 6960-6973
-
-
Jozefowski, S.1
Czerkies, M.2
Lukasik, A.3
Bielawska, A.4
Bielawski, J.5
Kwiatkowska, K.6
|