Effects of aging on circadian patterns of gene expression in the human prefrontal cortex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 1, 2016, Pages 206-211

  Chen, Cho Yi ^a   Logan, Ryan W ^b   Ma, Tianzhou ^a   Lewis, David A ^b   Tseng, George C ^a   Sibille, Etienne ^b,c,d   McClung, Colleen A ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Aging; Circadian rhythms; Gene expression; Postmortem; Prefrontal cortex

Indexed keywords

TRANSCRIPTION FACTOR CLOCK;

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; BRAIN; BRAIN REGION; CIRCADIAN RHYTHM; COGNITION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENOME; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; MICROARRAY ANALYSIS; MIDDLE AGED; MOOD; PREFRONTAL CORTEX; PRIORITY JOURNAL; SLEEP; TIME OF DEATH; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN GENOME; PATHOPHYSIOLOGY; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; CIRCADIAN RHYTHM; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREFRONTAL CORTEX; SLEEP; TRANSCRIPTION, GENETIC; YOUNG ADULT;

EID: 84953288973     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1508249112     Document Type: Article

References (60)

1. Patel VR, Eckel-Mahan K, Sassone-Corsi P, Baldi P (2014) How pervasive are circadian oscillations? Trends Cell Biol 24(6):329-331.
2. Baron KG, Reid KJ (2014) Circadian misalignment and health. Int Rev Psychiatry 26(2): 139-154.
3. Foster RG, Kreitzman L (2014) The rhythms of life: What your body clock means to you! Exp Physiol 99(4):599-606.
4. Reppert SM, Weaver DR (2001) Molecular analysis of mammalian circadian rhythms. Annu Rev Physiol 63:647-676.
5. Hogenesch JB, Panda S, Kay S, Takahashi JS (2003) Circadian transcriptional output in the SCN and liver of the mouse. Novartis Found Symp 253:171-180; discussion 52-55, 102-109, 180-183 passim.
6. Albrecht U (2012) Timing to perfection: The biology of central and peripheral circadian clocks. Neuron 74(2):246-260.
7. Logan RW, Williams WP, 3rd, McClung CA (2014) Circadian rhythms and addiction: Mechanistic insights and future directions. Behav Neurosci 128(3):387-412.
8. Mukherjee S, et al. (2010) Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior. Biol Psychiatry 68(6):503-511.
9. Sidor MM, et al. (2015) Daytime spikes in dopaminergic activity drive rapid moodcycling in mice. Mol Psychiatry 20(11):1406-1419.
10. Cho K, Ennaceur A, Cole JC, Suh CK (2000) Chronic jet lag produces cognitive deficits. J Neurosci 20(6):RC66.
11. Marquié JC, Tucker P, Folkard S, Gentil C, Ansiau D (2015) Chronic effects of shift work on cognition: Findings from the VISAT longitudinal study. Occup Environ Med 72(4):258-264.
12. Rouch I, Wild P, Ansiau D, Marquié JC (2005) Shiftwork experience, age and cognitive performance. Ergonomics 48(10):1282-1293.
13. Anderson JA, Campbell KL, Amer T, Grady CL, Hasher L (2014) Timing is everything: Age differences in the cognitive control network are modulated by time of day. Psychol Aging 29(3):648-657.
14. Walsh CM, et al. (2014) Weaker circadian activity rhythms are associated with poorer executive function in older women. Sleep 37(12):2009-2016.
15. Mulder CK, Gerkema MP, Van der Zee EA (2013) Circadian clocks and memory: Timeplace learning. Front Mol Neurosci 6:8.
16. Mulder CK, Papantoniou C, Gerkema MP, Van Der Zee EA (2014) Neither the SCN nor the adrenals are required for circadian time-place learning in mice. Chronobiol Int 31(9):1075-1092.
17. Roedel A, Storch C, Holsboer F, Ohl F (2006) Effects of light or dark phase testing on behavioural and cognitive performance in DBA mice. Lab Anim 40(4):371-381.
18. Karatsoreos IN, Bhagat S, Bloss EB, Morrison JH, McEwen BS (2011) Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proc Natl Acad Sci USA 108(4):1657-1662.
19. Youngstedt SD, Kripke DF, Elliott JA, Klauber MR (2001) Circadian abnormalities in older adults. J Pineal Res 31(3):264-272.
20. Yoon IY, et al. (2003) Age-related changes of circadian rhythms and sleep-wake cycles. J Am Geriatr Soc 51(8):1085-1091.
21. Hofman MA, Swaab DF (2006) Living by the clock: The circadian pacemaker in older people. Ageing Res Rev 5(1):33-51.
22. Daneault V, et al. (2014) Aging reduces the stimulating effect of blue light on cognitive brain functions. Sleep 37(1):85-96.
23. Pagani L, et al. (2011) Serum factors in older individuals change cellular clock properties. Proc Natl Acad Sci USA 108(17):7218-7223.
24. Li JZ, et al. (2013) Circadian patterns of gene expression in the human brain and disruption in major depressive disorder. Proc Natl Acad Sci USA 110(24):9950-9955.
25. Seney ML, et al. (2013) The role of genetic sex in affect regulation and expression of GABA-related genes across species. Front Psychiatry 4:104.
26. Chang LC, Lin HM, Sibille E, Tseng GC (2013) Meta-analysis methods for combining multiple expression profiles: Comparisons, statistical characterization and an application guideline. BMC Bioinformatics 14:368.
27. Storey JD (2003) The positive false discovery rate: A Bayesian interpretation and the q-value. Ann Stat 31(6):2013-2035.
28. Goriki A, et al. (2014) A novel protein, CHRONO, functions as a core component of the mammalian circadian clock. PLoS Biol 12(4):e1001839.
29. Annayev Y, et al. (2014) Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression. J Biol Chem 289(8):5013-5024.
30. Panda S, et al. (2002) Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109(3):307-320.
31. Hughes ME, et al. (2009) Harmonics of circadian gene transcription in mammals. PLoS Genet 5(4):e1000442.
32. Pagani M, et al. (2007) Imaging the neurobiological substrate of atypical depression by SPECT. Eur J Nucl Med Mol Imaging 34(1):110-120.
33. Nebel K, et al. (2005) On the neural basis of focused and divided attention. Brain Res Cogn Brain Res 25(3):760-776.
34. Dunlap JC (1999) Molecular bases for circadian clocks. Cell 96(2):271-290.
35. Houl JH, Yu W, Dudek SM, Hardin PE (2006) Drosophila CLOCK is constitutively expressed in circadian oscillator and non-oscillator cells. J Biol Rhythms 21(2):93-103.
36. Harbour VL, Weigl Y, Robinson B, Amir S (2014) Phase differences in expression of circadian clock genes in the central nucleus of the amygdala, dentate gyrus, and suprachiasmatic nucleus in the rat. PLoS One 9(7):e103309.
37. Lamont EW, Robinson B, Stewart J, Amir S (2005) The central and basolateral nuclei of the amygdala exhibit opposite diurnal rhythms of expression of the clock protein Period2. Proc Natl Acad Sci USA 102(11):4180-4184.
38. + channel family members localized in human telencephalon. J Biol Chem 274(35): 25018-25025.
39. Sewduth RN, et al. (2014) The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling. Nat Commun 5:4832.
40. Honda T, Yamamoto H, Ishii A, Inui M (2010) PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling. Mol Biol Cell 21(18):3269-3277.
41. Allen CN, et al. (1999) Orphanin-FQ/nociceptin (OFQ/N) modulates the activity of suprachiasmatic nucleus neurons. J Neurosci 19(6):2152-2160.
42. Miyakawa K, et al. (2007) ORL1 receptor-mediated down-regulation of mPER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle. Neuropharmacology 52(3):1055-1064.
43. Burger AM, et al. (2010) Role of the BCA2 ubiquitin E3 ligase in hormone responsive breast cancer. Open Cancer J 3(1):116-123.
44. Stevens RG, Brainard GC, Blask DE, Lockley SW, Motta ME (2014) Breast cancer and circadian disruption from electric lighting in the modern world. CA Cancer J Clin 64(3): 207-218.
45. Stojkovic K, Wing SS, Cermakian N (2014) A central role for ubiquitination within a circadian clock protein modification code. Front Mol Neurosci 7:69.
46. Myers BL, Badia P (1995) Changes in circadian rhythms and sleep quality with aging: Mechanisms and interventions. Neurosci Biobehav Rev 19(4):553-571.
47. Abe T, et al. (2011) Relation between morningness-eveningness score and depressive symptoms among patients with delayed sleep phase syndrome. Sleep Med 12(7): 680-684.
48. Adan A (1994) Chronotype and personality factors in the daily consumption of alcohol and psychostimulants. Addiction 89(4):455-462.
49. Giglio LM, et al. (2010) Circadian preference in bipolar disorder. Sleep Breath 14(2): 153-155.
50. Merikanto I, et al. (2013) Evening types are prone to depression. Chronobiol Int 30(5): 719-725.
51. Bachman D, Rabins P (2006) "Sundowning" and other temporally associated agitation states in dementia patients. Annu Rev Med 57:499-511.
52. Klaffke S, Staedt J (2006) Sundowning and circadian rhythm disorders in dementia. Acta Neurol Belg 106(4):168-175.
53. Tiribuzi R, et al. (2014) miR128 up-regulation correlates with impaired amyloid β(1-42) degradation in monocytes from patients with sporadic Alzheimer's disease. Neurobiol Aging 35(2):345-356.
54. Jin M, et al. (2014) miRNA-128 suppresses prostate cancer by inhibiting BMI-1 to inhibit tumor-initiating cells. Cancer Res 74(15):4183-4195.
55. Guo S, et al. (2014) miR-15a inhibits cell proliferation and epithelial to mesenchymal transition in pancreatic ductal adenocarcinoma by down-regulating Bmi-1 expression. Cancer Lett 344(1):40-46.
56. Bekris LM, et al. (2013) MicroRNA in Alzheimer's disease: An exploratory study in brain, cerebrospinal fluid and plasma. Biomarkers 18(5):455-466.
57. Terzibasi Tozzini E, et al. (2014) Regulation of microRNA expression in the neuronal stem cell niches during aging of the short-lived annual fish Nothobranchius furzeri. Front Cell Neurosci 8:51.
58. Eckel-Mahan KL, et al. (2013) Reprogramming of the circadian clock by nutritional challenge. Cell 155(7):1464-1478.
59. Stelzer G, et al. (2011) In-silico human genomics with GeneCards. Hum Genomics 5(6): 709-717.
60. Safran M, et al. (2010) GeneCards Version 3: The human gene integrator. Database (Oxford) 2010:baq020.