Comparison of Toxicity between Intensity-Modulated Radiotherapy and 3-Dimensional Conformal Radiotherapy for Locally Advanced Non-small-cell Lung Cancer

Clinical Lung Cancer

Volumn 17, Issue 1, 2016, Pages 18-23

  Ling, Diane C ^a   Hess, Clayton B ^a   Chen, Allen M ^b   Daly, Megan E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Elective nodal irradiation; Esophagitis; IMRT; Non small cell lung cancer; Pneumonitis

Indexed keywords

CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; ETOPOSIDE; PACLITAXEL;

3 DIMENSIONAL CONFORMAL RADIOTHERAPY; ACUTE TOXICITY; ADULT; ADVANCED CANCER; AGED; ARTICLE; COHORT ANALYSIS; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; DOSIMETRY; ESOPHAGITIS; EVALUATION STUDY; FEMALE; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MAJOR CLINICAL STUDY; MALE; NON SMALL CELL LUNG CANCER; OVERALL SURVIVAL; PERCUTANEOUS ENDOSCOPIC GASTROSTOMY; PNEUMONIA; RETROSPECTIVE STUDY; SURVIVAL; TREATMENT OUTCOME; TREND STUDY; WEIGHT REDUCTION; ADENOCARCINOMA; ADVERSE EFFECTS; CANCER STAGING; CARCINOMA, LARGE CELL; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CHEMORADIOTHERAPY; COMPARATIVE STUDY; CONFORMAL RADIOTHERAPY; FOLLOW UP; LUNG NEOPLASMS; MIDDLE AGED; ORGANS AT RISK; PATHOLOGY; PROGNOSIS; RADIATION RESPONSE; RADIATION TOLERANCE; RADIOTHERAPY DOSAGE; VERY ELDERLY;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, LARGE CELL; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CHEMORADIOTHERAPY; FEMALE; FOLLOW-UP STUDIES; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; ORGANS AT RISK; PROGNOSIS; RADIATION TOLERANCE; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; RADIOTHERAPY, INTENSITY-MODULATED; RETROSPECTIVE STUDIES;

EID: 84953273898     PISSN: 15257304     EISSN: 19380690     Source Type: Journal    
DOI: 10.1016/j.cllc.2015.07.006     Document Type: Article

References (16)

1. O. Chapet, B.A. Fraass, and R.K. Ten Haken Multiple fields may offer better esophagus sparing without increased probability of lung toxicity in optimized IMRT of lung tumors Int J Radiat Oncol Biol Phys 65 2006 255 265
2. I.S. Grills, D. Yan, A.A. Martinez, and et al. Potential for reduced toxicity and dose escalation in the treatment of inoperable non-small-cell lung cancer: a comparison of intensity-modulated radiation therapy (IMRT), 3D conformal radiation, and elective nodal irradiation Int J Radiat Oncol Biol Phys 57 2003 875 890
3. H.H. Liu, X. Wang, L. Dong, and et al. Feasibility of sparing lung and other thoracic structures with intensity-modulated radiotherapy for non-small-cell lung cancer Int J Radiat Oncol Biol Phys 58 2004 1268 1279
4. M. Schwarz, J. Van der Geer, M. Van Herk, and et al. Impact of geometrical uncertainties on 3D CRT and IMRT dose distributions for lung cancer treatment Int J Radiat Oncol Biol Phys 65 2006 1260 1269
5. J.P. Harris, J.D. Murphy, A.L. Hanlon, and et al. A population-based comparative effectiveness study of radiation therapy techniques in stage III non-small cell lung cancer Int J Radiat Oncol Biol Phys 88 2014 872 884
6. Z.X. Liao, R.R. Komaki, H.D. Thames Jr., and et al. Influence of technologic advances on outcomes in patients with unresectable, locally advanced non-small-cell lung cancer receiving concomitant chemoradiotherapy Int J Radiat Oncol Biol Phys 76 2010 775 781
7. S.M. Shirvani, A. Juloori, P.K. Allen, and et al. Comparison of 2 common radiation therapy techniques for definitive treatment of small cell lung cancer Int J Radiat Oncol Biol Phys 87 2013 139 147
8. S.S. Yom, Z. Liao, H.H. Liu, and et al. Initial evaluation of treatment-related pneumonitis in advanced-stage non-small-cell lung cancer patients treated with concurrent chemotherapy and intensity-modulated radiotherapy Int J Radiat Oncol Biol Phys 68 2007 94 102
9. S.M. Shirvani, J. Jiang, D.R. Gomez, and et al. Intensity modulated radiotherapy for stage III non-small cell lung cancer in the United States: predictors of use and association with toxicities Lung Cancer 82 2013 252 259
10. A.T. Fernandes, J. Shen, J. Finlay, and et al. Elective nodal irradiation (ENI) vs involved field radiotherapy (IFRT) for locally advanced non-small cell lung cancer (NSCLC): a comparative analysis of toxicities and clinical outcomes Radiother Oncol 95 2010 178 184
11. E.P. Sulman, R. Komaki, A.H. Klopp, and et al. Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer Radiat Oncol 4 2009 5
12. C.S. Chui, E. Yorke, and L. Hong The effects of intra-fraction organ motion on the delivery of intensity-modulated field with a multileaf collimator Med Phys 30 2003 1736 1746
13. L.E. Court, M. Wagar, D. Ionascu, and et al. Management of the interplay effect when using dynamic MLC sequences to treat moving targets Med Phys 35 2008 1926 1931
14. S.B. Jiang, C. Pope, K.M. Al Jarrah, and et al. An experimental investigation on intra-fractional organ motion effects in lung IMRT treatments Phys Med Biol 48 2003 1773 1784
15. B. Movsas, C. Hu, J. Sloan, and et al. Quality of life (QOL) analysis of the randomized radiation (RT) dose escalation NSCLC trial (RTOG 0617): the rest of the story Int J Radiat Oncol Biol Phys 87 2013 S1 S2
16. J.D. Bradley, R. Paulus, R. Komaki, and et al. Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study Lancet Oncol 16 2015 187 199