Toll-like receptor-4 is upregulated in plaque debris of patients with acute coronary syndrome more than Toll-like receptor-2

Heart and Vessels

Volumn 31, Issue 1, 2016, Pages 1-5

  Satoh, Shinji ^a   Yada, Ryoko ^a   Inoue, Hiroko ^a   Omura, Soichiro ^a   Ejima, Emiko ^a   Mori, Takahiro ^a   Takenaka, Katsuhiko ^a   Kawamura, Natsumi ^a   Numaguchi, Kotaro ^a   Mori, Etsuo ^a   Asoh, Akemi ^a   Nakamura, Toshihiro ^a   Hiyamuta, Koji ^a  

^a NATIONAL HOSPITAL ORGANIZATION KYUSHU MEDICAL CENTER   (Japan)

Author keywords

Acute coronary syndrome; Atherogenesis; Distal protection; Inflammation; Toll like receptor

Indexed keywords

MESSENGER RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ACUTE CORONARY SYNDROME; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; ATHEROGENESIS; CONTROLLED STUDY; EMBOLIC PROTECTION FILTER; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PATHOPHYSIOLOGY; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN ANALYSIS; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SEX RATIO; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; STABLE ANGINA PECTORIS; UNSTABLE ANGINA PECTORIS; UPREGULATION; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; GENETICS; JAPAN; METABOLISM; MIDDLE AGED;

ACUTE CORONARY SYNDROME; AGED; ANGINA, STABLE; ATHEROSCLEROSIS; FEMALE; HUMANS; JAPAN; MALE; MIDDLE AGED; PERCUTANEOUS CORONARY INTERVENTION; PLAQUE, ATHEROSCLEROTIC; PROSPECTIVE STUDIES; REAL-TIME POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 84952923487     PISSN: 09108327     EISSN: 16152573     Source Type: Journal    
DOI: 10.1007/s00380-014-0565-9     Document Type: Article

References (17)

1. Libby P (2002) Inflammation in atherosclerosis. Nature 420:868–874
2. Fuster V, Badimon L, Badimon JJ, Chesebro JH (1992) The pathogenesis of coronary artery disease and the acute coronary syndromes (first of two parts). N Engl J Med 326:242–250
3. Cole JE, Georgiou E, Monaco C (2010) The expression and functions of Toll-like receptors in atherosclerosis. Mediators Inflamm 393946:393918. doi:10.1155/2010/393946
4. Hodgkinson CP, Ye S (2011) Toll-like receptors, their ligands, and atherosclerosis. Sci World J 11:437–453
5. Katoh S, Honda S, Watanabe T, Suzuki S, Ishino M, Kitahara T, Funayama A, Netsu S, Sasaki T, Shishido T, Miyamoto T, Sadahiro M, Kubota I (2014) Atrial endothelial impairment through Toll-like receptor 4 signaling causes atrial thrombogenesis. Heart Vessels 29:263–272
6. Chao W (2009) Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart. Am J Physiol Heart Circ Physiol 296:H1–H12
7. Arslan F, Keogh B, McGuirk P, Parker AE (2010) TLR2 and TLR4 in ischemia reperfusion injury. Mediators Inflamm 704202:704208. doi:10.1155/2010/704202
8. Shao L, Zhang P, Zhang Y, Lu Q, Ma A (2013) TLR3 and TLR4 as potential clinically biomarkers of cardiovascular risk in coronary artery disease (CAD) patients. Heart Vessels. doi:10.1007/s00380-00013-00421-00383
9. Ward JR, Wilson HL, Francis SE, Crossman DC, Sabroe I (2009) Translational mini-review Series on immunology of vascular disease: inflammation, infections and Toll-like receptors in cardiovascular disease. Clin Exp Immunol 156:386–394
10. Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DEJ, Chavey WEN, Fesmire FM, Hochman JS, Levin TN, Lincoff AM, Peterson ED, Theroux P, Wenger NK, Wright RS, Smith SCJ, Jacobs AK, Halperin JL, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura R, Ornato JP, Page RL, Riegel B (2007) ACC/AHA 2007 guidelines for the management of patients with unstable angina/non–ST-elevation myocardial infarction. A report of the American College of Cardiology/American Heart Association task force on practice guidelines (writing committee to revise the 2002 guidelines for the management of patients with unstable angina/non–ST-elevation myocardial infarction). Circulation 116:803–877
11. Silber S, Albertsson P, Avilés FF, Camici PG, Colombo A, Hamm C, Jørgensen E, Marco J, Nordrehaug JE, Ruzyllo W, Urban P, Stone GW, Wijns W (2005) Guidelines for percutaneous coronary interventions. The task force for percutaneous coronary interventions of the European Society of Cardiology. Eur Heart J 26:804–847
12. Maier W, Altwegg LA, Corti R, Gay S, Hersberger M, Maly FE, Sütsch SG, Roffi M, Neidhart M, Eberli FR, Tanner FC, Gobbi S, von Eckardstein A, Lüscher TF (2005) Inflammatory markers at the site of ruptured plaque in acute myocardial infarction. Locally increased interleukin-6 and serum amyloid A but decreased C-reactive protein. Circulation 111:1355–1361
13. Van’t Hof AWJ, Liem A, Suryapranata H, Hoorntje JCA, de Boer M-J, Zijilstra F, Group obotZMIS (1998) Angiographic assessment of myocardial reperfusion in patients treated with primary angioplasy for acute myocardial infarction. myocardial blush grade. Circulation 97:2302–2306
14. TIMI Study Group (1985) The thrombolysis in myocardial infarction (TIMI) trial: phase I findings. N Engl J Med 312:932–936
15. Mabin T, Holmes DRJ, Smith HC, Vlietstra RE, Bove AA, Reeder GS, Chesebro JH, Bresnahan JF, Orszulak TA (1985) Intracoronary thrombus: role in coronary occlusion complicating percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 5:198–202
16. Chao W (2009) Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart. Am J Physiol Heart Circ Physiol 296:H1–H12
17. Riad A, Jäger S, Sobirey M, Escher F, Yaulema-Riss A, Westermann D, Karatas A, Heimesaat MM, Bereswill S, Dragun D, Pauschinger M, Schultheiss HP, Tschöpe C (2008) Toll-like receptor-4 modulates survival by induction of left ventricular remodeling after myocardial infarction in mice. J Immunol 180:6954–6961